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Search results 4201 to 4300 out of 4757 for Apoe

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Hits by Strain

Type Details Score
Genotype
Symbol: Apoe/Apoe Hdl5/Hdl5
Background: involves: C3H/HeJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Tg(Eno2-APP*751)10Cord/?
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Lipg/Lipg
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Lgals3/Lgals3
Background: involves: 129/Sv * C57BL/6 * SJL
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Il1rn/Il1rn
Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Rag2/Rag2
Background: involves: 129P2/OlaHsd * 129S/SvEv
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Rag2/Rag2<+>
Background: involves: 129P2/OlaHsd * 129S/SvEv
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Igs7/?
Background: involves: 129S1/Sv * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Tnfsf4/Tnfsf4
Background: involves: C3H/HeJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Csf1/Csf1
Background: involves: 129P2/OlaHsd * C3HeB/Fe * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Lcat/Lcat
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Nceh1/Nceh1
Background: B6.129-Nceh1 Apoe
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Mmp9/Mmp9
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Clcn7/Clcn7 Tg(APOE-cre)VITew/?
Background: B6.Cg-Clcn7 Tg(APOE-cre)VITew
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Cdkn1a/Cdkn1a
Background: B6.129-Apoe Cdkn1a
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Ncf1/Ncf1
Background: involves: 129P2/OlaHsd * 129S2/SvPas
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Itgb3/Itgb3
Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Ccr2/Ccr2<+>
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Ccr2/Ccr2
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Ccr2/Ccr2
Background: B6.Cg-Apoe Ccr2
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Ifng/Ifng
Background: B6.129-Apoe Ifng
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Cxcl10/Cxcl10
Background: B6.129-Cxcl10 Apoe
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Crp/Crp
Background: B6.Cg-Crp Apoe
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(APOE-ABCA1)30Ssf/?
Background: C57BL/6N-Tg(APOE-ABCA1)30Ssf
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Ccr1/Ccr1
Background: involves: 129P2/OlaHsd * 129S4/SvJae
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Cyp19a1/Cyp19a1
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(APOE-FGF23*R176Q)#Ack/?
Background: involves: C57BL/6J * CBA
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Hsd11b1/Hsd11b1
Background: B6.129-Hsd11b1 Apoe
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Fasl/Fasl
Background: B6.Cg-Fasl Apoe
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Klf15/Klf15
Background: involves: 129P2/OlaHsd * 129X1/SvJ
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Glg1/Glg1<+>
Background: B6J.129P2-Apoe Glg1
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Sprr3/Sprr3
Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J * SJL
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Tg(APPSWE)2576Kha/?
Background: involves: C57BL/6 * C57BL/6N * SJL
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Svep1/Svep1
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Thbs4/Thbs4
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoa1/Apoa1 Apoe/Apoe
Background: involves: 129P2/OlaHsd
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Lrp1/Lrp1
Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Lrp1/Lrp1
Background: involves: 129P2/OlaHsd
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe
Background: B6(SJL)-Apoe/J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Tg(Sry)2Ei/?
Background: B6.129P2-Apoe Tg(Sry)2Ei
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Sry/Sry<+>
Background: B6.129-Apoe Sry
Zygosity: cx
Has Mutant Allele: true
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Ribas V
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Myeloid-specific estrogen receptor alpha deficiency impairs metabolic homeostasis and accelerates atherosclerotic lesion development.
Volume: 108
Issue: 39
Pages: 16457-62
Publication
First Author: Dulabon L
Year: 2000
Journal: Neuron
Title: Reelin binds alpha3beta1 integrin and inhibits neuronal migration.
Volume: 27
Issue: 1
Pages: 33-44
Publication  
First Author: Barthelson K
Year: 2022
Journal: Dis Model Mech
Title: Brain transcriptomes of zebrafish and mouse Alzheimer's disease knock-in models imply early disrupted energy metabolism.
Volume: 15
Issue: 1
Publication
First Author: Liu Q
Year: 2007
Journal: Neuron
Title: Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1.
Volume: 56
Issue: 1
Pages: 66-78
Publication
First Author: Hsich E
Year: 2000
Journal: Circulation
Title: Vascular effects following homozygous disruption of p47(phox) : An essential component of NADPH oxidase.
Volume: 101
Issue: 11
Pages: 1234-6
Publication  
First Author: Choi HY
Year: 2013
Journal: Elife
Title: APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice.
Volume: 2
Pages: e00220
Publication
First Author: Yang C
Year: 2019
Journal: J Exp Med
Title: Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques.
Volume: 216
Issue: 5
Pages: 1182-1198
Publication
First Author: Kress GJ
Year: 2018
Journal: J Exp Med
Title: Regulation of amyloid-β dynamics and pathology by the circadian clock.
Volume: 215
Issue: 4
Pages: 1059-1068
Publication
First Author: Fernandes GW
Year: 2018
Journal: Cell Rep
Title: The Foxo1-Inducible Transcriptional Repressor Zfp125 Causes Hepatic Steatosis and Hypercholesterolemia.
Volume: 22
Issue: 2
Pages: 523-534
Publication
First Author: Heimerl S
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Caveolin-1 deficiency alters plasma lipid and lipoprotein profiles in mice.
Volume: 367
Issue: 4
Pages: 826-33
Publication
First Author: Cramer PE
Year: 2012
Journal: Science
Title: ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models.
Volume: 335
Issue: 6075
Pages: 1503-6
Publication
First Author: Chakrabarty P
Year: 2015
Journal: Neuron
Title: IL-10 alters immunoproteostasis in APP mice, increasing plaque burden and worsening cognitive behavior.
Volume: 85
Issue: 3
Pages: 519-33
Publication
First Author: Wang S
Year: 2012
Journal: Nat Med
Title: Activation of AMP-activated protein kinase α2 by nicotine instigates formation of abdominal aortic aneurysms in mice in vivo.
Volume: 18
Issue: 6
Pages: 902-10
Publication
First Author: Liu CC
Year: 2017
Journal: Neuron
Title: ApoE4 Accelerates Early Seeding of Amyloid Pathology.
Volume: 96
Issue: 5
Pages: 1024-1032.e3
Publication
First Author: Hedrick CC
Year: 1993
Journal: J Biol Chem
Title: Influence of mouse apolipoprotein A-II on plasma lipoproteins in transgenic mice.
Volume: 268
Issue: 27
Pages: 20676-82
Publication
First Author: Savas JN
Year: 2017
Journal: Cell Rep
Title: Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer's Disease-like Pathology.
Volume: 21
Issue: 9
Pages: 2614-2627
Publication
First Author: Audrain M
Year: 2021
Journal: Alzheimers Dement
Title: Reactive or transgenic increase in microglial TYROBP reveals a TREM2-independent TYROBP-APOE link in wild-type and Alzheimer's-related mice.
Volume: 17
Issue: 2
Pages: 149-163
Publication  
First Author: Liu T
Year: 2020
Journal: J Exp Med
Title: Multi-omic comparison of Alzheimer's variants in human ESC-derived microglia reveals convergence at APOE.
Volume: 217
Issue: 12
Publication      
First Author: Hou X
Year: 2023
Journal: Neuron
Title: Differential and substrate-specific inhibition of γ-secretase by the C-terminal region of ApoE2, ApoE3, and ApoE4.
Publication
First Author: Yılmaz S
Year: 2024
Journal: iScience
Title: Exploring temporal and sex-linked dysregulation in Alzheimer disease phosphoproteome.
Volume: 27
Issue: 10
Pages: 110941
Publication
First Author: Parhizkar S
Year: 2019
Journal: Nat Neurosci
Title: Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE.
Volume: 22
Issue: 2
Pages: 191-204
Publication
First Author: Rothstein NM
Year: 2001
Journal: J Infect Dis
Title: Effect of azithromycin on murine arteriosclerosis exacerbated by Chlamydia pneumoniae.
Volume: 183
Issue: 2
Pages: 232-238
Publication
First Author: Law SW
Year: 1985
Journal: Biochem Biophys Res Commun
Title: Human ApoB-100 gene resides in the p23----pter region of chromosome 2.
Volume: 131
Issue: 2
Pages: 1003-12
Publication
First Author: Yerle M
Year: 1990
Journal: Cytogenet Cell Genet
Title: Localization on pig chromosome 6 of markers GPI, APOE, and ENO1, carried by human chromosomes 1 and 19, using in situ hybridization.
Volume: 54
Issue: 1-2
Pages: 86-91
Publication
First Author: de Knijff P
Year: 1991
Journal: Atherosclerosis
Title: Apolipoprotein E polymorphism affects plasma levels of lipoprotein(a).
Volume: 90
Issue: 2-3
Pages: 169-74
Publication
First Author: Shi W
Year: 2002
Journal: Arterioscler Thromb Vasc Biol
Title: Atherosclerosis in C3H/HeJ mice reconstituted with apolipoprotein E-null bone marrow.
Volume: 22
Issue: 4
Pages: 650-5
Publication
First Author: Kang DE
Year: 2000
Journal: J Clin Invest
Title: Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway.
Volume: 106
Issue: 9
Pages: 1159-66
Publication
First Author: Smith JD
Year: 1990
Journal: J Biol Chem
Title: Accumulation of human apolipoprotein E in the plasma of transgenic mice.
Volume: 265
Issue: 25
Pages: 14709-12
Publication
First Author: Smith JD
Year: 1998
Journal: Neurobiol Aging
Title: Human apolipoprotein E allele-specific brain expressing transgenic mice.
Volume: 19
Issue: 5
Pages: 407-13
Publication
First Author: Kim J
Year: 2009
Journal: Neuron
Title: The role of apolipoprotein E in Alzheimer's disease.
Volume: 63
Issue: 3
Pages: 287-303
Publication    
First Author: Gao J
Year: 2017
Journal: Elife
Title: The E3 ubiquitin ligase IDOL regulates synaptic ApoER2 levels and is important for plasticity and learning.
Volume: 6
Publication
First Author: Moser VA
Year: 2021
Journal: iScience
Title: Microglial transcription profiles in mouse and human are driven by APOE4 and sex.
Volume: 24
Issue: 11
Pages: 103238
Publication  
First Author: Xu Y
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Autophagy deficiency modulates microglial lipid homeostasis and aggravates tau pathology and spreading.
Volume: 118
Issue: 27
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Köster A
Year: 2005
Journal: Endocrinology
Title: Transgenic angiopoietin-like (angptl)4 overexpression and targeted disruption of angptl4 and angptl3: regulation of triglyceride metabolism.
Volume: 146
Issue: 11
Pages: 4943-50
Publication
First Author: Faber K
Year: 2006
Journal: Mol Endocrinol
Title: Megalin is a receptor for apolipoprotein M, and kidney-specific megalin-deficiency confers urinary excretion of apolipoprotein M.
Volume: 20
Issue: 1
Pages: 212-8
Publication
First Author: Kaseda R
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Megalin-mediated endocytosis of cystatin C in proximal tubule cells.
Volume: 357
Issue: 4
Pages: 1130-4
Strain
Attribute String: targeted mutation, mutant strain, congenic
Strain
Attribute String: targeted mutation, congenic
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: targeted mutation, mutant strain, congenic
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: targeted mutation, mutant stock
Strain
Attribute String: congenic, targeted mutation
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: targeted mutation, mutant strain, congenic
Strain
Attribute String: congenic, mutant strain, spontaneous mutation, targeted mutation
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: congenic, mutant strain, targeted mutation
Publication
First Author: Karaplis AC
Year: 2012
Journal: Endocrinology
Title: Mineralizing enthesopathy is a common feature of renal phosphate-wasting disorders attributed to FGF23 and is exacerbated by standard therapy in hyp mice.
Volume: 153
Issue: 12
Pages: 5906-17