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Search results 4201 to 4300 out of 9662 for Egf

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Hits by Pathway

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Hits by Strain

Type Details Score
Genotype
Genotype
Symbol: Ccbe1/Ccbe1<+>
Background: C57BL/6NCrl-Ccbe1/MbpMmucd
Zygosity: ht
Has Mutant Allele: true
•
•
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•
•
Genotype
Genotype
Symbol: Celsr1/Celsr1<+>
Background: C57BL/6N-Celsr1/MbpMmucd
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Celsr1/Celsr1 Wnt5a/Wnt5a
Background: involves: 129 * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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•
•
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•
Genotype
Genotype
Symbol: Ccbe1/Ccbe1<+>
Background: involves: 129S5/SvEvBrd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
•
•
•
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•
Genotype
Genotype
Symbol: Celsr1/Celsr1<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrl
Zygosity: ht
Has Mutant Allele: true
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•
•
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•
Genotype
Genotype
Symbol: Celsr1/Celsr1 Celsr2/Celsr2
Background: B6.Cg-Celsr1 Celsr2
Zygosity: cx
Has Mutant Allele: true
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Protein
Q80Z71
Organism: Mus musculus/domesticus
Length: 1560  
Fragment?: false
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Protein
E9Q1F6
Organism: Mus musculus/domesticus
Length: 1296  
Fragment?: false
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Protein
Q61555
Organism: Mus musculus/domesticus
Length: 2907  
Fragment?: false
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Publication
10960788 | J:64339
First Author: Kanai Y
Year: 2000
Journal: Mech Dev
Title: Identification of a stromal cell type characterized by the secretion of a soluble integrin-binding protein, MFG-E8, in mouse early gonadogenesis.
Volume: 96
Issue: 2
Pages: 223-7
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Publication
29784671 | J:264107
 
First Author: Ghimire SR
Year: 2018
Journal: Development
Title: A non-autonomous function of the core PCP protein VANGL2 directs peripheral axon turning in the developing cochlea.
Volume: 145
Issue: 12
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Publication
38199575 | J:345661
First Author: Datta R
Year: 2024
Journal: J Biol Chem
Title: PTP1B mediates the inhibitory effect of MFGE8 on insulin signaling through the β5 integrin.
Volume: 300
Issue: 2
Pages: 105631
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Publication
9101712 | J:39205
First Author: Aoki N
Year: 1997
Journal: Biochim Biophys Acta
Title: Stage specific expression of milk fat globule membrane glycoproteins in mouse mammary gland: comparison of MFG-E8, butyrophilin, and CD36 with a major milk protein, beta-casein.
Volume: 1334
Issue: 2-3
Pages: 182-90
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Publication
9395447 | J:44628
First Author: Yamaguchi A
Year: 1997
Journal: J Biol Chem
Title: An Eps homology (EH) domain protein that binds to the Ral-GTPase target, RalBP1.
Volume: 272
Issue: 50
Pages: 31230-4
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Protein
O88840
Organism: Mus musculus/domesticus
Length: 3857  
Fragment?: false
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Publication
16687519 | J:108647
First Author: Montcouquiol M
Year: 2006
Journal: J Neurosci
Title: Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals.
Volume: 26
Issue: 19
Pages: 5265-75
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Publication
29551912 | J:288805
 
First Author: Pensold D
Year: 2018
Journal: J Exp Neurosci
Title: Single-Cell Transcriptomics Reveals Regulators of Neuronal Migration and Maturation During Brain Development.
Volume: 12
Pages: 1179069518760783
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Publication
34407949 | J:310416
 
First Author: Feng B
Year: 2021
Journal: Sci Adv
Title: Planar cell polarity signaling components are a direct target of β-amyloid-associated degeneration of glutamatergic synapses.
Volume: 7
Issue: 34
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Publication
19454719 | J:148851
First Author: Aziz MM
Year: 2009
Journal: J Immunol
Title: MFG-E8 attenuates intestinal inflammation in murine experimental colitis by modulating osteopontin-dependent alphavbeta3 integrin signaling.
Volume: 182
Issue: 11
Pages: 7222-32
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Protein
Q9JI18
Organism: Mus musculus/domesticus
Length: 4599  
Fragment?: false
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Protein
Q8VI56
Organism: Mus musculus/domesticus
Length: 1905  
Fragment?: false
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Protein
Q91ZX7
Organism: Mus musculus/domesticus
Length: 4545  
Fragment?: false
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•
•
Protein
A2ARV4
Organism: Mus musculus/domesticus
Length: 4660  
Fragment?: false
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•
Protein
A2API5
Organism: Mus musculus/domesticus
Length: 4599  
Fragment?: false
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Protein
E9Q202
Organism: Mus musculus/domesticus
Length: 3357  
Fragment?: false
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Protein
A0A0R4J0I9
Organism: Mus musculus/domesticus
Length: 4545  
Fragment?: false
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Protein Domain
IPR039436 | Asteroid_dom
Type: Domain
Description: This entry represents a domain found in Asteroid, which plays a possible role in EGF receptor signalling [].
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Publication
17827153 | J:126817
First Author: Li T
Year: 2007
Journal: J Biol Chem
Title: Epidermal growth factor receptor and notch pathways participate in the tumor suppressor function of gamma-secretase.
Volume: 282
Issue: 44
Pages: 32264-73
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Protein
P10493
Organism: Mus musculus/domesticus
Length: 1245  
Fragment?: false
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Strain
MGI:7311712 | B6.Cg-Notch1<tm1Con> Terc<tm1Rdp>
Attribute String: congenic, mutant strain, targeted mutation
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Publication
28346225 | J:244124
First Author: Theodoris CV
Year: 2017
Journal: J Clin Invest
Title: Long telomeres protect against age-dependent cardiac disease caused by NOTCH1 haploinsufficiency.
Volume: 127
Issue: 5
Pages: 1683-1688
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Publication
33237915 | J:298932
First Author: Joll JE 2nd
Year: 2020
Journal: PLoS One
Title: Genetic ablation of serotonin receptor 2B improves aortic valve hemodynamics of Notch1 heterozygous mice in a high-cholesterol diet model.
Volume: 15
Issue: 11
Pages: e0238407
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Publication
33303684 | J:302585
 
First Author: Theodoris CV
Year: 2021
Journal: Science
Title: Network-based screen in iPSC-derived cells reveals therapeutic candidate for heart valve disease.
Volume: 371
Issue: 6530
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Publication
9342050 | J:43309
First Author: Meyer D
Year: 1997
Journal: Development
Title: Isoform-specific expression and function of neuregulin.
Volume: 124
Issue: 18
Pages: 3575-86
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Allele
Jag2<tm1Grid> | MGI:2657215
Name: jagged 2; targeted mutation 1, Tom Gridley
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Notch3<tm1Grid> | MGI:2687010
Name: notch 3; targeted mutation 1, Tom Gridley
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:3584180 | B6.129P2-Cspg5<tm1Fgr>
Attribute String: targeted mutation, mutant strain, congenic
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Publication
23889129 | J:227884
First Author: Jüttner R
Year: 2013
Journal: Eur J Neurosci
Title: Impaired presynaptic function and elimination of synapses at premature stages during postnatal development of the cerebellum in the absence of CALEB (CSPG5/neuroglycan C).
Volume: 38
Issue: 9
Pages: 3270-80
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Allele
Notch2<tm2Grid> | MGI:3617327
Name: notch 2; targeted mutation 2, Tom Gridley
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:6145724 | C57BL/6J-Tg(Gcnt1-HBEGF)3Rin/RinRbrc
Attribute String: mutant strain, coisogenic, transgenic
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Genotype
Genotype
Symbol: Cspg5/Cspg5
Background: B6.129P2-Cspg5
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Notch1/Notch1<+> Terc/Terc
Background: B6.Cg-Notch1 Terc
Zygosity: cx
Has Mutant Allele: true
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Protein
Q61592
Organism: Mus musculus/domesticus
Length: 674  
Fragment?: false
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Protein
O88322
Organism: Mus musculus/domesticus
Length: 1403  
Fragment?: false
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Protein
Q61549
Organism: Mus musculus/domesticus
Length: 931  
Fragment?: false
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Protein
Q3U9R0
Organism: Mus musculus/domesticus
Length: 931  
Fragment?: false
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Protein
Q3US45
Organism: Mus musculus/domesticus
Length: 1403  
Fragment?: false
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Protein
Q3U1M9
Organism: Mus musculus/domesticus
Length: 915  
Fragment?: false
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Protein
Q8CFA3
Organism: Mus musculus/domesticus
Length: 1403  
Fragment?: false
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Protein
Q3TPN0
Organism: Mus musculus/domesticus
Length: 1403  
Fragment?: false
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Protein
Q8R5G0
Organism: Mus musculus/domesticus
Length: 1403  
Fragment?: false
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Protein
Q8C6Z2
Organism: Mus musculus/domesticus
Length: 1294  
Fragment?: false
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Protein
Q80YS4
Organism: Mus musculus/domesticus
Length: 1072  
Fragment?: false
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Protein
Q05793
Organism: Mus musculus/domesticus
Length: 3707  
Fragment?: false
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Protein
Q3UHH3
Organism: Mus musculus/domesticus
Length: 2672  
Fragment?: false
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Protein
B1B0C7
Organism: Mus musculus/domesticus
Length: 4375  
Fragment?: false
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Protein
E9PZ16
Organism: Mus musculus/domesticus
Length: 4383  
Fragment?: false
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Protein
A2AJ76
Organism: Mus musculus/domesticus
Length: 5100  
Fragment?: false
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Protein
D3YXG0
Organism: Mus musculus/domesticus
Length: 5634  
Fragment?: false
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Publication
11404089 | J:70066
First Author: Morais da Silva S
Year: 2001
Journal: Mech Dev
Title: The expression pattern of tomoregulin-1 in urodele limb regeneration and mouse limb development.
Volume: 104
Issue: 1-2
Pages: 125-8
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Publication
30758284 | J:275100
   
First Author: Lindenmaier LB
Year: 2019
Journal: Elife
Title: Dystroglycan is a scaffold for extracellular axon guidance decisions.
Volume: 8
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Genotype
Genotype
Symbol: Celsr3/Celsr3 Foxg1/Foxg1<+>
Background: involves: 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Celsr3/Celsr3 Tg(mI56i-cre,EGFP)1Kc/?
Background: involves: 129P2/OlaHsd * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Celsr3/Celsr3 Tg(Gsx2-icre)1Kess/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Celsr3/Celsr3 Tg(Nkx2-1-cre)1Wdr/?
Background: involves: 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Celsr3/Celsr3 Tg(Gsx2-icre)1Kess/? Tg(Nkx2-1-cre)1Wdr/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Celsr1/Celsr1<+> Ptk7/Ptk7<+>
Background: involves: 101/H * BALB/c * BALB/cAnN * C3H/HeH
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Celsr1/Celsr1<+> Vangl2/Vangl2<+>
Background: involves: 101/H * BALB/c * C3H/HeH * CBA * LPT/Le
Zygosity: cx
Has Mutant Allele: true
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•
Genotype
Genotype
Symbol: Celsr1/Celsr1<+> Vangl2/Vangl2<+>
Background: C3H.Cg-Vangl2 Celsr1
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Celsr1/Celsr1<+> Scrib/Scrib<+>
Background: C3H.Cg-Scrib Celsr1
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Apoe/Apoe Svep1/Svep1 Tg(Myh11-icre/ERT2)1Soff/?
Background: involves: 129P2/OlaHsd * C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Eogt/Eogt Rbpj/Rbpj<+>
Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Svep1/Svep1<+>
Background: C57BL/6N-Svep1/J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Svep1/Svep1<+>
Background: involves: C57BL/6N
Zygosity: ht
Has Mutant Allele: true
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Publication
25002511 | J:212261
First Author: Qu Y
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Genetic evidence that Celsr3 and Celsr2, together with Fzd3, regulate forebrain wiring in a Vangl-independent manner.
Volume: 111
Issue: 29
Pages: E2996-3004
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Protein
Q5DU39
Organism: Mus musculus/domesticus
Length: 1484  
Fragment?: true
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Publication
23996638 | J:202995
First Author: Ren DD
Year: 2013
Journal: Dev Dyn
Title: Testin interacts with vangl2 genetically to regulate inner ear sensory cell orientation and the normal development of the female reproductive tract in mice.
Volume: 242
Issue: 12
Pages: 1454-65
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Publication
28159525 | J:240403
First Author: Duncan JS
Year: 2017
Journal: Dev Biol
Title: Celsr1 coordinates the planar polarity of vestibular hair cells during inner ear development.
Volume: 423
Issue: 2
Pages: 126-137
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Publication
21031554 | J:230484
First Author: Miller AM
Year: 2010
Journal: J Comp Neurol
Title: Composition of the migratory mass during development of the olfactory nerve.
Volume: 518
Issue: 24
Pages: 4825-41
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Publication
26206421 | J:317244
 
First Author: Lee J
Year: 2015
Journal: Exp Mol Med
Title: Fetal hematopoietic stem cells express MFG-E8 during mouse embryogenesis.
Volume: 47
Pages: e174
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Publication
10932191 | J:63816
First Author: Nolan PM
Year: 2000
Journal: Nat Genet
Title: A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.
Volume: 25
Issue: 4
Pages: 440-3
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Protein
Q06806
Organism: Mus musculus/domesticus
Length: 1134  
Fragment?: false
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Protein
M0QWP1
Organism: Mus musculus/domesticus
Length: 2034  
Fragment?: false
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Protein
A0A076N9U7
Organism: Mus musculus/domesticus
Length: 3309  
Fragment?: false
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Protein
Q571L9
Organism: Mus musculus/domesticus
Length: 1671  
Fragment?: true
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Protein
B1AWS8
Organism: Mus musculus/domesticus
Length: 1123  
Fragment?: false
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Publication
25915128 | J:233664
First Author: Luxenburg C
Year: 2015
Journal: Nat Cell Biol
Title: Wdr1-mediated cell shape dynamics and cortical tension are essential for epidermal planar cell polarity.
Volume: 17
Issue: 5
Pages: 592-604
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Publication
23824190 | J:314570
First Author: Babayeva S
Year: 2013
Journal: J Biol Chem
Title: Planar cell polarity pathway regulates nephrin endocytosis in developing podocytes.
Volume: 288
Issue: 33
Pages: 24035-48
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Publication
28599846 | J:247897
First Author: Cetera M
Year: 2017
Journal: Dev Biol
Title: Planar cell polarity-dependent and independent functions in the emergence of tissue-scale hair follicle patterns.
Volume: 428
Issue: 1
Pages: 188-203
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Publication
22654117 | J:315946
First Author: Sato-Nishiuchi R
Year: 2012
Journal: J Biol Chem
Title: Polydom/SVEP1 is a ligand for integrin α9β1.
Volume: 287
Issue: 30
Pages: 25615-30
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Publication
15284116 | J:94891
First Author: Morelli AE
Year: 2004
Journal: Blood
Title: Endocytosis, intracellular sorting, and processing of exosomes by dendritic cells.
Volume: 104
Issue: 10
Pages: 3257-66
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Publication
19268448 | J:148363
First Author: Sewell W
Year: 2009
Journal: Dev Biol
Title: Cyclical expression of the Notch/Wnt regulator Nrarp requires modulation by Dll3 in somitogenesis.
Volume: 329
Issue: 2
Pages: 400-9
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GO Term
GO:1905251 | epidermal growth factor receptor signaling pathway involved in heart process
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Publication
38827526 | J:349011
 
First Author: Stansak KL
Year: 2024
Journal: Front Cell Dev Biol
Title: PCP auto count: a novel Fiji/ImageJ plug-in for automated quantification of planar cell polarity and cell counting.
Volume: 12
Pages: 1394031
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Publication
11171333 | J:67157
First Author: McCright B
Year: 2001
Journal: Development
Title: Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation.
Volume: 128
Issue: 4
Pages: 491-502
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Publication
14732396 | J:87368
First Author: Raetzman LT
Year: 2004
Journal: Dev Biol
Title: Developmental regulation of Notch signaling genes in the embryonic pituitary: Prop1 deficiency affects Notch2 expression.
Volume: 265
Issue: 2
Pages: 329-40
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Publication
11923214 | J:75954
First Author: Dunwoodie SL
Year: 2002
Journal: Development
Title: Axial skeletal defects caused by mutation in the spondylocostal dysplasia/pudgy gene Dll3 are associated with disruption of the segmentation clock within the presomitic mesoderm.
Volume: 129
Issue: 7
Pages: 1795-806
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Publication
12753746 | J:83475
First Author: Kumano K
Year: 2003
Journal: Immunity
Title: Notch1 but not Notch2 is essential for generating hematopoietic stem cells from endothelial cells.
Volume: 18
Issue: 5
Pages: 699-711
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Publication
21493891 | J:187551
First Author: Nus M
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: Diet-induced aortic valve disease in mice haploinsufficient for the Notch pathway effector RBPJK/CSL.
Volume: 31
Issue: 7
Pages: 1580-8
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Publication
14701881 | J:87765
First Author: Timmerman LA
Year: 2004
Journal: Genes Dev
Title: Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation.
Volume: 18
Issue: 1
Pages: 99-115
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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