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Search results 4201 to 4300 out of 6467 for Myc

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Hits by Strain

Type Details Score
Protein
F6PWU6
Organism: Mus musculus/domesticus
Length: 293  
Fragment?: true
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Protein
A0A0J9YUP9
Organism: Mus musculus/domesticus
Length: 642  
Fragment?: false
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Protein
Q5SWE2
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: true
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Protein
Q3UZA4
Organism: Mus musculus/domesticus
Length: 536  
Fragment?: false
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Protein
A2AHY3
Organism: Mus musculus/domesticus
Length: 168  
Fragment?: false
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Protein
A0A0J9YTU7
Organism: Mus musculus/domesticus
Length: 541  
Fragment?: false
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Protein
Q6P6L3
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: false
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Protein
E9PWE4
Organism: Mus musculus/domesticus
Length: 648  
Fragment?: false
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Protein
A0A140LID4
Organism: Mus musculus/domesticus
Length: 91  
Fragment?: true
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Protein
O09135
Organism: Mus musculus/domesticus
Length: 310  
Fragment?: false
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Protein
A0A0J9YUK1
Organism: Mus musculus/domesticus
Length: 641  
Fragment?: false
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Protein
A0A0R4J056
Organism: Mus musculus/domesticus
Length: 355  
Fragment?: false
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Protein
Q91XK1
Organism: Mus musculus/domesticus
Length: 511  
Fragment?: false
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Protein
E9Q722
Organism: Mus musculus/domesticus
Length: 296  
Fragment?: false
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Protein
Q545C0
Organism: Mus musculus/domesticus
Length: 330  
Fragment?: false
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Protein
A0A1W2P7S0
Organism: Mus musculus/domesticus
Length: 169  
Fragment?: false
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Protein
A0A1W2P7V8
Organism: Mus musculus/domesticus
Length: 94  
Fragment?: false
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Protein
Q3UU13
Organism: Mus musculus/domesticus
Length: 216  
Fragment?: false
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Protein
Q6F6D5
Organism: Mus musculus/domesticus
Length: 222  
Fragment?: false
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Protein
F6T941
Organism: Mus musculus/domesticus
Length: 638  
Fragment?: true
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Protein
G5E8D8
Organism: Mus musculus/domesticus
Length: 917  
Fragment?: false
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Protein
V9GWT9
Organism: Mus musculus/domesticus
Length: 166  
Fragment?: false
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Protein
A0A0J9YVG2
Organism: Mus musculus/domesticus
Length: 641  
Fragment?: false
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Protein
Q3UQH7
Organism: Mus musculus/domesticus
Length: 310  
Fragment?: false
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Protein
A0A0J9YVI1
Organism: Mus musculus/domesticus
Length: 610  
Fragment?: false
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Protein
Q3UGG9
Organism: Mus musculus/domesticus
Length: 591  
Fragment?: false
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Protein
A0A0R4J011
Organism: Mus musculus/domesticus
Length: 649  
Fragment?: false
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Protein
A0A2R8W6R9
Organism: Mus musculus/domesticus
Length: 199  
Fragment?: true
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Protein
F6Q4B6
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: true
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Protein
A6H5V4
Organism: Mus musculus/domesticus
Length: 370  
Fragment?: false
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Protein
A5D6P6
Organism: Mus musculus/domesticus
Length: 160  
Fragment?: false
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Protein
Q53WV9
Organism: Mus musculus/domesticus
Length: 231  
Fragment?: false
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Protein
Q6GTH9
Organism: Mus musculus/domesticus
Length: 263  
Fragment?: false
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Protein
Q32NY8
Organism: Mus musculus/domesticus
Length: 489  
Fragment?: false
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Protein
A2ATA7
Organism: Mus musculus/domesticus
Length: 324  
Fragment?: false
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Protein
U5KBZ7
Organism: Mus musculus/domesticus
Length: 64  
Fragment?: true
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Protein
Q91VN7
Organism: Mus musculus/domesticus
Length: 209  
Fragment?: false
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Protein
Q3UZ22
Organism: Mus musculus/domesticus
Length: 199  
Fragment?: false
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Protein
Q3UXQ3
Organism: Mus musculus/domesticus
Length: 477  
Fragment?: true
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Protein
Q0VEJ8
Organism: Mus musculus/domesticus
Length: 223  
Fragment?: false
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Protein
Q91YV0
Organism: Mus musculus/domesticus
Length: 507  
Fragment?: false
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Publication
2175254 | -
First Author: Krause M
Year: 1990
Journal: Cell
Title: CeMyoD accumulation defines the body wall muscle cell fate during C. elegans embryogenesis.
Volume: 63
Issue: 5
Pages: 907-19
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Publication
1521738 | -
First Author: Kato GJ
Year: 1992
Journal: FASEB J
Title: Function of the c-Myc oncoprotein.
Volume: 6
Issue: 12
Pages: 3065-72
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Protein Domain
IPR011598 | bHLH_dom
Type: Domain
Description: A number of eukaryotic proteins, which probably are sequence specific DNA-binding proteins that act as transcription factors, share a conserved domain of 40 to 50 amino acid residues. It has been proposed []that this domain is formed of two amphipathic helices joined by a variable length linker region that could form a loop. This 'helix-loop-helix' (HLH) domain mediates protein dimerization and has been found in the proteins listed below []. Most of these proteins have an extra basic region of about 15 amino acid residues that is adjacent to the HLH domain and specifically binds to DNA. They are referred as basic helix-loop-helix proteins (bHLH), and are classified in two groups: class A (ubiquitous) and class B (tissue-specific). Members of the bHLH family bind variations on the core sequence 'CANNTG', also referred to asthe E-box motif. The homo- or heterodimerization mediated by the HLH domain is independent of, but necessary for DNA binding, as two basic regions are required for DNA binding activity. The HLH proteins lacking the basic domain (Emc, Id) function as negative regulators, since they form heterodimers, but fail to bind DNA. The hairy-related proteins (hairy, E(spl), deadpan) also repress transcription although they can bind DNA. The proteins of this subfamily act together with co-repressor proteins, like groucho, through their -terminal motif WRPW.Proteins containing a HLH domain include:The myc family of cellular oncogenes [], which is currently known to contain four members: c-myc, N-myc, L-myc, and B-myc. The myc genes are thought to play a role in cellular differentiation and proliferation.Proteins involved in myogenesis (the induction of muscle cells). In mammals MyoD1 (Myf-3), myogenin (Myf-4), Myf-5, and Myf-6 (Mrf4 or herculin), in birds CMD1 (QMF-1), in Xenopus MyoD and MF25, in Caenorhabditis elegans CeMyoD, and in Drosophila nautilus (nau).Vertebrate proteins that bind specific DNA sequences ('E boxes') in various immunoglobulin chains enhancers: E2A or ITF-1 (E12/pan-2 and E47/pan-1), ITF-2 (tcf4), TFE3, and TFEB.Vertebrate neurogenic differentiation factor 1 that acts as differentiation factor during neurogenesis.Vertebrate MAX protein, a transcription regulator that forms a sequence- specific DNA-binding protein complex with myc or mad.Vertebrate Max Interacting Protein 1 (MXI1 protein) which acts as a transcriptional repressor and may antagonize myc transcriptional activity by competing for max.Proteins of the bHLH/PAS superfamily which are transcriptional activators. In mammals, AH receptor nuclear translocator (ARNT), single-minded homologues (SIM1 and SIM2), hypoxia-inducible factor 1 alpha (HIF1A), AH receptor (AHR), neuronal pas domain proteins (NPAS1 and NPAS2), endothelial pas domain protein 1 (EPAS1), mouse ARNT2, and human BMAL1. In Drosophila, single-minded (SIM), AH receptor nuclear translocator (ARNT), trachealess protein (TRH), and similar protein (SIMA).Mammalian transcription factors HES, which repress transcription by acting on two types of DNA sequences, the E box and the N box.Mammalian MAD protein (max dimerizer) which acts as transcriptional repressor and may antagonize myc transcriptional activity by competing for max.Mammalian Upstream Stimulatory Factor 1 and 2 (USF1 and USF2), which bind to a symmetrical DNA sequence that is found in a variety of viral and cellular promoters.Human lyl-1 protein; which is involved, by chromosomal translocation, in T- cell leukemia.Human transcription factor AP-4.Mouse helix-loop-helix proteins MATH-1 and MATH-2 which activate E box- dependent transcription in collaboration with E47.Mammalian stem cell protein (SCL) (also known as tal1), a protein which may play an important role in hemopoietic differentiation. SCL is involved, by chromosomal translocation, in stem-cell leukemia.Mammalian proteins Id1 to Id4 []. Id (inhibitor of DNA binding) proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting binding to DNA.Drosophila extra-macrochaetae (emc) protein, which participates in sensory organ patterning by antagonizing the neurogenic activity of the achaete- scute complex. Emc is the homologue of mammalian Id proteins.Human Sterol Regulatory Element Binding Protein 1 (SREBP-1), a transcriptional activator that binds to the sterol regulatory element 1 (SRE-1) found in the flanking region of the LDLR gene and in other genes.Drosophila achaete-scute (AS-C) complex proteins T3 (l'sc), T4 (scute), T5 (achaete) and T8 (asense). The AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.Mammalian homologues of achaete-scute proteins, the MASH-1 and MASH-2 proteins.Drosophila atonal protein (ato) which is involved in neurogenesis.
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Publication
27321927 | J:239715
First Author: Galazo MJ
Year: 2016
Journal: Neuron
Title: Corticothalamic Projection Neuron Development beyond Subtype Specification: Fog2 and Intersectional Controls Regulate Intraclass Neuronal Diversity.
Volume: 91
Issue: 1
Pages: 90-106
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Publication
1325649 | J:2256
First Author: Burbach KM
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor.
Volume: 89
Issue: 17
Pages: 8185-9
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Publication
1287475 | J:15805
First Author: Haupt Y
Year: 1992
Journal: Mol Biol Rep
Title: Nucleotide sequence of bup, an upstream gene in the bmi-1 proviral insertion locus.
Volume: 17
Issue: 1
Pages: 17-20
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Publication
14981236 | J:88660
First Author: Bera TK
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: NGEP, a gene encoding a membrane protein detected only in prostate cancer and normal prostate.
Volume: 101
Issue: 9
Pages: 3059-64
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Publication
32542325 | J:304368
First Author: Numata A
Year: 2020
Journal: Blood
Title: Lysine acetyltransferase Tip60 is required for hematopoietic stem cell maintenance.
Volume: 136
Issue: 15
Pages: 1735-1747
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Publication
31398338 | J:279945
First Author: Sanghvi VR
Year: 2019
Journal: Cell
Title: The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase.
Volume: 178
Issue: 4
Pages: 807-819.e21
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Publication
9931421 | J:51804
First Author: Jadayel DM
Year: 1998
Journal: Gene
Title: The BCL7 gene family: deletion of BCL7B in Williams syndrome.
Volume: 224
Issue: 1-2
Pages: 35-44
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Publication
3690668 | J:20067
First Author: Davis RL
Year: 1987
Journal: Cell
Title: Expression of a single transfected cDNA converts fibroblasts to myoblasts.
Volume: 51
Issue: 6
Pages: 987-1000
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Publication
21654807 | J:173451
First Author: Maekawa M
Year: 2011
Journal: Nature
Title: Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1.
Volume: 474
Issue: 7350
Pages: 225-9
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Publication
23217706 | J:219058
First Author: Sebastián C
Year: 2012
Journal: Cell
Title: The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism.
Volume: 151
Issue: 6
Pages: 1185-99
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Publication
27180906 | J:234471
First Author: Kugel S
Year: 2016
Journal: Cell
Title: SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b.
Volume: 165
Issue: 6
Pages: 1401-1415
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Publication
19745809 | J:154718
First Author: Pan D
Year: 2009
Journal: EMBO J
Title: SnoN functions as a tumour suppressor by inducing premature senescence.
Volume: 28
Issue: 22
Pages: 3500-13
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Publication
21911376 | J:176646
First Author: Cho SH
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Glycolytic rate and lymphomagenesis depend on PARP14, an ADP ribosyltransferase of the B aggressive lymphoma (BAL) family.
Volume: 108
Issue: 38
Pages: 15972-7
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Publication
34520734 | J:355252
First Author: Freeman-Cook K
Year: 2021
Journal: Cancer Cell
Title: Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor.
Volume: 39
Issue: 10
Pages: 1404-1421.e11
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Publication
27396325 | J:238681
First Author: Ribeiro D
Year: 2016
Journal: Cell Rep
Title: Regulation of Nuclear Hormone Receptors by MYCN-Driven miRNAs Impacts Neural Differentiation and Survival in Neuroblastoma Patients.
Volume: 16
Issue: 4
Pages: 979-993
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Publication
31685988 | J:282941
First Author: Schmidt S
Year: 2019
Journal: Nat Cell Biol
Title: A MYC-GCN2-eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer.
Volume: 21
Issue: 11
Pages: 1413-1424
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Publication
28507025 | J:252345
First Author: Cunningham CA
Year: 2017
Journal: J Immunol
Title: Cutting Edge: Defective Aerobic Glycolysis Defines the Distinct Effector Function in Antigen-Activated CD8+ Recent Thymic Emigrants.
Volume: 198
Issue: 12
Pages: 4575-4580
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Publication
24684846 | J:210811
First Author: Morfouace M
Year: 2014
Journal: Cancer Cell
Title: Pemetrexed and gemcitabine as combination therapy for the treatment of Group3 medulloblastoma.
Volume: 25
Issue: 4
Pages: 516-29
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Publication
22340590 | J:181463
First Author: Pei Y
Year: 2012
Journal: Cancer Cell
Title: An animal model of MYC-driven medulloblastoma.
Volume: 21
Issue: 2
Pages: 155-67
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Publication
27373157 | J:238584
First Author: Jahchan NS
Year: 2016
Journal: Cell Rep
Title: Identification and Targeting of Long-Term Tumor-Propagating Cells in Small Cell Lung Cancer.
Volume: 16
Issue: 3
Pages: 644-56
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Publication
37802055 | J:342146
First Author: Rajbhandari N
Year: 2023
Journal: Cancer Cell
Title: Single-cell mapping identifies MSI(+) cells as a common origin for diverse subtypes of pancreatic cancer.
Volume: 41
Issue: 11
Pages: 1989-2005.e9
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Publication
16432227 | J:105997
First Author: Pusapati RV
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: ATM promotes apoptosis and suppresses tumorigenesis in response to Myc.
Volume: 103
Issue: 5
Pages: 1446-51
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Publication
33674596 | J:304975
First Author: Ischenko I
Year: 2021
Journal: Nat Commun
Title: KRAS drives immune evasion in a genetic model of pancreatic cancer.
Volume: 12
Issue: 1
Pages: 1482
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Publication
34784501 | J:321718
First Author: Gerlach BD
Year: 2021
Journal: Cell Metab
Title: Efferocytosis induces macrophage proliferation to help resolve tissue injury.
Volume: 33
Issue: 12
Pages: 2445-2463.e8
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Publication
9856457 | J:51430
First Author: ElShamy WM
Year: 1998
Journal: Neuron
Title: Growth arrest failure, G1 restriction point override, and S phase death of sensory precursor cells in the absence of neurotrophin-3.
Volume: 21
Issue: 5
Pages: 1003-15
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Publication
25577439 | J:254602
First Author: Gu AD
Year: 2015
Journal: Immunity
Title: A critical role for transcription factor Smad4 in T cell function that is independent of transforming growth factor β receptor signaling.
Volume: 42
Issue: 1
Pages: 68-79
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Publication
29988091 | J:282530
First Author: Newton RH
Year: 2018
Journal: Nat Immunol
Title: Maintenance of CD4 T cell fitness through regulation of Foxo1.
Volume: 19
Issue: 8
Pages: 838-848
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Publication
28416194 | J:256189
First Author: Angelin A
Year: 2017
Journal: Cell Metab
Title: Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments.
Volume: 25
Issue: 6
Pages: 1282-1293.e7
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Publication
12499254 | J:80829
First Author: Wotton S
Year: 2002
Journal: Cancer Res
Title: Proviral insertion indicates a dominant oncogenic role for Runx1/AML-1 in T-cell lymphoma.
Volume: 62
Issue: 24
Pages: 7181-5
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Publication
18268325 | J:143960
First Author: Descargues P
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: IKKalpha is a critical coregulator of a Smad4-independent TGFbeta-Smad2/3 signaling pathway that controls keratinocyte differentiation.
Volume: 105
Issue: 7
Pages: 2487-92
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Publication
35479397 | J:337995
First Author: Aibara D
Year: 2022
Journal: iScience
Title: Gene repression through epigenetic modulation by PPARA enhances hepatocellular proliferation.
Volume: 25
Issue: 5
Pages: 104196
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Publication
34757798 | J:314666
First Author: Balasubramanian R
Year: 2021
Journal: Sci Adv
Title: Phase transition specified by a binary code patterns the vertebrate eye cup.
Volume: 7
Issue: 46
Pages: eabj9846
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Publication
21400495 | J:177017
First Author: Vasilevsky NA
Year: 2011
Journal: Eur J Immunol
Title: OX40 engagement stabilizes Mxd4 and Mnt protein levels in antigen-stimulated T cells leading to an increase in cell survival.
Volume: 41
Issue: 4
Pages: 1024-34
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Publication
32522871 | J:294362
First Author: Sommermann T
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Functional interplay of Epstein-Barr virus oncoproteins in a mouse model of B cell lymphomagenesis.
Volume: 117
Issue: 25
Pages: 14421-14432
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Publication
29162623 | J:256300
First Author: Lolo FN
Year: 2017
Journal: Biol Open
Title: Elimination of classically-activated macrophages in tumor-conditioned medium by alternatively-activated macrophages.
Volume: 6
Issue: 12
Pages: 1897-1903
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Publication
19647225 | J:151973
First Author: Ehrenreiter K
Year: 2009
Journal: Cancer Cell
Title: Raf-1 addiction in Ras-induced skin carcinogenesis.
Volume: 16
Issue: 2
Pages: 149-60
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Publication
10344759 | J:55311
First Author: Kamijo T
Year: 1999
Journal: Cancer Res
Title: Loss of the ARF tumor suppressor reverses premature replicative arrest but not radiation hypersensitivity arising from disabled atm function.
Volume: 59
Issue: 10
Pages: 2464-9
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Publication
24581491 | J:211315
First Author: Mori M
Year: 2014
Journal: Cell
Title: Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancer.
Volume: 156
Issue: 5
Pages: 893-906
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Publication
31092557 | J:317985
First Author: Nowak DG
Year: 2019
Journal: J Cell Biol
Title: The PHLPP2 phosphatase is a druggable driver of prostate cancer progression.
Volume: 218
Issue: 6
Pages: 1943-1957
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Publication
32470392 | J:293702
First Author: Augert A
Year: 2020
Journal: Cancer Cell
Title: MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer.
Volume: 38
Issue: 1
Pages: 97-114.e7
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Publication
38330136 | J:345232
First Author: Gardner EE
Year: 2024
Journal: Science
Title: Lineage-specific intolerance to oncogenic drivers restricts histological transformation.
Volume: 383
Issue: 6683
Pages: eadj1415
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Publication
28490518 | J:243118
First Author: Sen T
Year: 2017
Journal: Cancer Res
Title: CHK1 Inhibition in Small-Cell Lung Cancer Produces Single-Agent Activity in Biomarker-Defined Disease Subsets and Combination Activity with Cisplatin or Olaparib.
Volume: 77
Issue: 14
Pages: 3870-3884
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Publication
27298335 | J:233306
First Author: Kim DW
Year: 2016
Journal: Genes Dev
Title: Genetic requirement for Mycl and efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer.
Volume: 30
Issue: 11
Pages: 1289-99
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Publication
34236315 | J:308027
   
First Author: Mathsyaraja H
Year: 2021
Journal: Elife
Title: Loss of MGA repression mediated by an atypical polycomb complex promotes tumor progression and invasiveness.
Volume: 10
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Publication
28827447 | J:246431
First Author: Tanaka T
Year: 2017
Journal: J Exp Med
Title: Internal deletion of BCOR reveals a tumor suppressor function for BCOR in T lymphocyte malignancies.
Volume: 214
Issue: 10
Pages: 2901-2913
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Publication
35020836 | J:326021
First Author: Antoszewski M
Year: 2022
Journal: Blood
Title: Tcf1 is essential for initiation of oncogenic Notch1-driven chromatin topology in T-ALL.
Volume: 139
Issue: 16
Pages: 2483-2498
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Publication
30107177 | J:264234
First Author: Vanden Bempt M
Year: 2018
Journal: Cancer Cell
Title: Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia.
Volume: 34
Issue: 2
Pages: 271-285.e7
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Publication
21685889 | J:174453
First Author: Wray J
Year: 2011
Journal: Nat Cell Biol
Title: Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation.
Volume: 13
Issue: 7
Pages: 838-45
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Publication
34758313 | J:320924
First Author: Chen WS
Year: 2021
Journal: Cell Rep
Title: Single-cell transcriptomics reveals opposing roles of Shp2 in Myc-driven liver tumor cells and microenvironment.
Volume: 37
Issue: 6
Pages: 109974
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