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Search results 4301 to 4400 out of 4701 for Bcl2

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Genotype
Genotype
Symbol: Bax/Bax Pcdhg/Pcdhg Tg(Chx10-EGFP/cre,-ALPP)2Clc/?
Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor Tg(H2-K-BCL2)1Josd/?
Background: involves: 129 * C3H * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd79b/Cd79b Tg(BCL2)22Wehi/? Tg(IghelMD4)4Ccg/? Tg(Rag2-Igb)1Mnz/?
Background: involves: 129S1/Sv * C57BL/6 * C57BL/6JWehi * SJL/JWehi
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bax/Bax Ret/Ret Tg(CAG-cre/Esr1*)5Amc/?
Background: involves: 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Il2rg/Il2rg Tg(Cd8a*-cre)B8Asin/? Tg(LCKprBCL2)36Sjk/?
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Il7r/Il7r Tg(Cd4-cre)1Cwi/? Tg(H2-K-BCL2)1Josd/?
Background: involves: 129S6/SvEvTac * C57BL/6 * C3H * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CD2-TcraF5,CD2-TcrbF5)1Kio/? Tg(Cd4-BCL2*G101A*D102A*D103A)AWnt/?
Background: involves: C57BL/6 * C57BL/10
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CD2-TcraF5,CD2-TcrbF5)1Kio/? Tg(LCKprBCL2)36Sjk/?
Background: involves: C57BL/6 * C57BL/10
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(LCKprBCL2)36Sjk/? Tg(TcraH-Y,TcrbH-Y)71Vbo/?
Background: involves: C57BL/6 * C57BL/6J * DBA/2J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Cd4-BCL2*G101A*D102A*D103A)AWnt/? Tg(Nr4a1-EGFP/cre)820Khog/?
Background: involves: C57BL/6 * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(LCKprBCL2)36Sjk/? Tg(Nr4a1-EGFP/cre)820Khog/?
Background: involves: C57BL/6 * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Becn1/Becn1 Tg(CAG-EGFP/Map1lc3b)53Nmz/?
Background: involves: 129 * C57BL/6 * C57BL/6J * C57BL/6NCrlj * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mef2b/Mef2b<+> Tg(BCL2/IGH)M23Tjd/? Tg(Cr2-cre)3Cgn/?
Background: involves: C3H/He * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bax/Bax Chn1/Chn1 Tg(Hlxb9-GFP)1Tmj/?
Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd19/Cd19<+> Tbl1xr1/Tbl1xr1 Tg(Vav-BCL2)69Jad/?
Background: involves: 129P2/OlaHsd * C57BL/6J * C57BL/6N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bax/Bax Hoxa5/Hoxa5 Hoxc5/Hoxc5 Olig2/Olig2<+> Tg(Hlxb9-GFP)1Tmj/?
Background: involves: 129X1/SvJ * C57BL/6J * CBA * SJL
Zygosity: cn
Has Mutant Allele: true
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Publication
18551131 | -
First Author: Kvansakul M
Year: 2008
Journal: Cell Death Differ
Title: Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands.
Volume: 15
Issue: 10
Pages: 1564-71
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Publication
20159550 | -
First Author: Chipuk JE
Year: 2010
Journal: Mol Cell
Title: The BCL-2 family reunion.
Volume: 37
Issue: 3
Pages: 299-310
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Publication
17095659 | J:116164
First Author: Dequéant ML
Year: 2006
Journal: Science
Title: A complex oscillating network of signaling genes underlies the mouse segmentation clock.
Volume: 314
Issue: 5805
Pages: 1595-8
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Publication
35864088 | J:326958
First Author: Sapir T
Year: 2022
Journal: Nat Commun
Title: Heterogeneous nuclear ribonucleoprotein U (HNRNPU) safeguards the developing mouse cortex.
Volume: 13
Issue: 1
Pages: 4209
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Publication
20498273 | J:162790
First Author: Sasaki K
Year: 2010
Journal: Mol Cell Biol
Title: PAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasis.
Volume: 30
Issue: 15
Pages: 3864-74
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Protein
Q9CPT0
Organism: Mus musculus/domesticus
Length: 328  
Fragment?: false
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Protein
P47741
Organism: Mus musculus/domesticus
Length: 272  
Fragment?: false
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Protein
B1ASL3
Organism: Mus musculus/domesticus
Length: 272  
Fragment?: false
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Publication
17062731 | J:137502
First Author: Dzhagalov I
Year: 2007
Journal: Blood
Title: The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophages.
Volume: 109
Issue: 4
Pages: 1620-6
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Publication
31601924 | J:284252
First Author: Fontaine MAC
Year: 2019
Journal: Sci Rep
Title: Low human and murine Mcl-1 expression leads to a pro-apoptotic plaque phenotype enriched in giant-cells.
Volume: 9
Issue: 1
Pages: 14547
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Publication
38474193 | J:346610
 
First Author: Révész C
Year: 2024
Journal: Int J Mol Sci
Title: Neutrophils and NADPH Oxidases Are Major Contributors to Mild but Not Severe Ischemic Acute Kidney Injury in Mice.
Volume: 25
Issue: 5
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Publication
24836575 | J:213225
First Author: Schwab L
Year: 2014
Journal: Nat Med
Title: Neutrophil granulocytes recruited upon translocation of intestinal bacteria enhance graft-versus-host disease via tissue damage.
Volume: 20
Issue: 6
Pages: 648-54
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Publication
37737207 | J:341054
First Author: Zhang L
Year: 2023
Journal: Cell Death Dis
Title: Mitochondrial IRG1 traps MCL-1 to induce hepatocyte apoptosis and promote carcinogenesis.
Volume: 14
Issue: 9
Pages: 625
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Publication
28283060 | J:241289
First Author: Ho CCM
Year: 2017
Journal: Cell
Title: Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling.
Volume: 168
Issue: 6
Pages: 1041-1052.e18
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Publication
33440165 | J:304296
First Author: Philips T
Year: 2021
Journal: Cell Rep
Title: MCT1 Deletion in Oligodendrocyte Lineage Cells Causes Late-Onset Hypomyelination and Axonal Degeneration.
Volume: 34
Issue: 2
Pages: 108610
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Publication
22001390 | J:179080
First Author: Lilla JN
Year: 2011
Journal: Blood
Title: Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1fl/fl mice.
Volume: 118
Issue: 26
Pages: 6930-8
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Publication
20467439 | J:186356
First Author: Pawlikowska P
Year: 2010
Journal: Cell Death Differ
Title: ATM-dependent expression of IEX-1 controls nuclear accumulation of Mcl-1 and the DNA damage response.
Volume: 17
Issue: 11
Pages: 1739-50
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Publication
28475176 | J:261297
First Author: Moretti C
Year: 2017
Journal: Cell Death Differ
Title: SLY regulates genes involved in chromatin remodeling and interacts with TBL1XR1 during sperm differentiation.
Volume: 24
Issue: 6
Pages: 1029-1044
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Publication
30288342 | J:278854
First Author: Almeida FF
Year: 2018
Journal: Oncoimmunology
Title: A point mutation in the Ncr1 signal peptide impairs the development of innate lymphoid cell subsets.
Volume: 7
Issue: 10
Pages: e1475875
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Publication
15798198 | J:97637
First Author: Liu H
Year: 2005
Journal: Mol Cell Biol
Title: Stabilization and enhancement of the antiapoptotic activity of mcl-1 by TCTP.
Volume: 25
Issue: 8
Pages: 3117-26
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Protein
F7CUQ1
Organism: Mus musculus/domesticus
Length: 146  
Fragment?: false
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Protein
Q91WX5
Organism: Mus musculus/domesticus
Length: 151  
Fragment?: false
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Publication
33218272 | J:313636
First Author: Choong CJ
Year: 2021
Journal: Autophagy
Title: Alternative mitochondrial quality control mediated by extracellular release.
Volume: 17
Issue: 10
Pages: 2962-2974
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Publication
31066324 | J:346539
First Author: Livingston MJ
Year: 2019
Journal: Autophagy
Title: Clearance of damaged mitochondria via mitophagy is important to the protective effect of ischemic preconditioning in kidneys.
Volume: 15
Issue: 12
Pages: 2142-2162
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Publication
21119107 | J:170369
First Author: Aukema SM
Year: 2011
Journal: Blood
Title: Double-hit B-cell lymphomas.
Volume: 117
Issue: 8
Pages: 2319-31
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Publication
28713948 | J:271863
First Author: Cheng XW
Year: 2017
Journal: Mol Med Rep
Title: MicroRNA‑126 inhibits endothelial permeability and apoptosis in apolipoprotein E‑knockout mice fed a high‑fat diet.
Volume: 16
Issue: 3
Pages: 3061-3068
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Publication
34373755 | J:314239
First Author: Park D
Year: 2021
Journal: Theranostics
Title: Discovery of Small Molecule Bak Activator for Lung Cancer Therapy.
Volume: 11
Issue: 17
Pages: 8500-8516
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Publication
25944088 | J:318251
 
First Author: Major JL
Year: 2015
Journal: J Mol Cell Cardiol
Title: Interplay between the E2F pathway and β-adrenergic signaling in the pathological hypertrophic response of myocardium.
Volume: 84
Pages: 179-90
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Publication
30485804 | J:270778
First Author: Vince JE
Year: 2018
Journal: Cell Rep
Title: The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation.
Volume: 25
Issue: 9
Pages: 2339-2353.e4
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Publication
21325504 | J:169444
First Author: Armstrong A
Year: 2011
Journal: J Neurosci
Title: Frizzled3 is required for neurogenesis and target innervation during sympathetic nervous system development.
Volume: 31
Issue: 7
Pages: 2371-81
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Publication
19020035 | J:142362
First Author: Ben-Zvi A
Year: 2008
Journal: J Neurosci
Title: The Semaphorin receptor PlexinA3 mediates neuronal apoptosis during dorsal root ganglia development.
Volume: 28
Issue: 47
Pages: 12427-32
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Publication
16546096 | J:113322
First Author: Delogu A
Year: 2006
Journal: Immunity
Title: Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells.
Volume: 24
Issue: 3
Pages: 269-81
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Publication
27303042 | J:234285
First Author: Siggs OM
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Mutation of Fnip1 is associated with B-cell deficiency, cardiomyopathy, and elevated AMPK activity.
Volume: 113
Issue: 26
Pages: E3706-15
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Publication
18436203 | J:136687
First Author: Suzuki H
Year: 2008
Journal: Dev Biol
Title: Nanos3 maintains the germ cell lineage in the mouse by suppressing both Bax-dependent and -independent apoptotic pathways.
Volume: 318
Issue: 1
Pages: 133-42
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Publication
21624937 | J:176824
First Author: Hsu FC
Year: 2011
Journal: J Exp Med
Title: NKAP is required for T cell maturation and acquisition of functional competency.
Volume: 208
Issue: 6
Pages: 1291-304
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Publication
23481390 | J:205750
 
First Author: Thapa P
Year: 2013
Journal: Nat Commun
Title: The transcriptional repressor NKAP is required for the development of iNKT cells.
Volume: 4
Pages: 1582
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Publication
29898399 | J:271108
First Author: Yamamoto S
Year: 2018
Journal: Cell Rep
Title: Autophagy Differentially Regulates Insulin Production and Insulin Sensitivity.
Volume: 23
Issue: 11
Pages: 3286-3299
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Publication
24036309 | J:203797
First Author: Maatouk DM
Year: 2013
Journal: Dev Biol
Title: Disruption of mitotic arrest precedes precocious differentiation and transdifferentiation of pregranulosa cells in the perinatal Wnt4 mutant ovary.
Volume: 383
Issue: 2
Pages: 295-306
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Publication
9498742 | J:112062
First Author: Van Parijs L
Year: 1998
Journal: J Immunol
Title: Functional roles of Fas and Bcl-2-regulated apoptosis of T lymphocytes.
Volume: 160
Issue: 5
Pages: 2065-71
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Publication
9492007 | J:110425
First Author: Van Parijs L
Year: 1998
Journal: Immunity
Title: The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens.
Volume: 8
Issue: 2
Pages: 265-74
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Publication
15744305 | J:96586
First Author: Janssen EM
Year: 2005
Journal: Nature
Title: CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death.
Volume: 434
Issue: 7029
Pages: 88-93
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Publication
25158854 | J:232152
First Author: Nedvetsky PI
Year: 2014
Journal: Dev Cell
Title: Parasympathetic innervation regulates tubulogenesis in the developing salivary gland.
Volume: 30
Issue: 4
Pages: 449-62
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Publication
35999236 | J:336998
First Author: Szeto C
Year: 2022
Journal: Nat Commun
Title: Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus.
Volume: 13
Issue: 1
Pages: 4951
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Publication
10435582 | J:110456
First Author: Haks MC
Year: 1999
Journal: Immunity
Title: Pre-TCR signaling and inactivation of p53 induces crucial cell survival pathways in pre-T cells.
Volume: 11
Issue: 1
Pages: 91-101
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Publication
16357220 | J:103922
First Author: Morales M
Year: 2005
Journal: Genes Dev
Title: The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor.
Volume: 19
Issue: 24
Pages: 3043-54
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Publication
18023370 | J:127623
First Author: Van Laethem F
Year: 2007
Journal: Immunity
Title: Deletion of CD4 and CD8 coreceptors permits generation of alphabetaT cells that recognize antigens independently of the MHC.
Volume: 27
Issue: 5
Pages: 735-50
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Publication
11447288 | J:93058
First Author: Tan JT
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: IL-7 is critical for homeostatic proliferation and survival of naive T cells.
Volume: 98
Issue: 15
Pages: 8732-7
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Publication
15728489 | J:97710
First Author: Rodriguez-Galán MC
Year: 2005
Journal: J Immunol
Title: Synergistic effect of IL-2, IL-12, and IL-18 on thymocyte apoptosis and Th1/Th2 cytokine expression.
Volume: 174
Issue: 5
Pages: 2796-804
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Publication
24984151 | J:220146
First Author: Nair VS
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Down-regulation of Tet2 prevents TSDR demethylation in IL2 deficient regulatory T cells.
Volume: 450
Issue: 1
Pages: 918-24
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Publication
17935075 | J:126334
First Author: Carrio R
Year: 2007
Journal: Eur J Immunol
Title: Non-redundant role for IL-7R signaling for the survival of CD8+ memory T cells.
Volume: 37
Issue: 11
Pages: 3078-88
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Publication
19228815 | J:149777
First Author: Speiran K
Year: 2009
Journal: J Leukoc Biol
Title: Endogenous suppression of mast cell development and survival by IL-4 and IL-10.
Volume: 85
Issue: 5
Pages: 826-36
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Publication
35443279 | J:326289
First Author: Leung W
Year: 2022
Journal: Cancer Discov
Title: SETD2 Haploinsufficiency Enhances Germinal Center-Associated AICDA Somatic Hypermutation to Drive B-cell Lymphomagenesis.
Volume: 12
Issue: 7
Pages: 1782-1803
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Publication
32954360 | J:317184
First Author: Chesi M
Year: 2020
Journal: Blood Cancer Discov
Title: Monosomic loss of MIR15A/MIR16-1 is a driver of multiple myeloma proliferation and disease progression.
Volume: 1
Issue: 1
Pages: 68-81
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Publication
17676052 | J:125101
First Author: Kirsch DG
Year: 2007
Journal: Nat Med
Title: A spatially and temporally restricted mouse model of soft tissue sarcoma.
Volume: 13
Issue: 8
Pages: 992-7
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Publication
20392943 | J:159854
First Author: Uesaka T
Year: 2010
Journal: J Neurosci
Title: Neural precursor death is central to the pathogenesis of intestinal aganglionosis in Ret hypomorphic mice.
Volume: 30
Issue: 15
Pages: 5211-8
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Publication
30485805 | J:271647
First Author: Chauhan D
Year: 2018
Journal: Cell Rep
Title: BAX/BAK-Induced Apoptosis Results in Caspase-8-Dependent IL-1β Maturation in Macrophages.
Volume: 25
Issue: 9
Pages: 2354-2368.e5
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Publication
33434191 | J:301294
First Author: Slupe AM
Year: 2021
Journal: PLoS One
Title: GABAergic neurons are susceptible to BAX-dependent apoptosis following isoflurane exposure in the neonatal period.
Volume: 16
Issue: 1
Pages: e0238799
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Publication
21911424 | J:177288
First Author: Josefsson EC
Year: 2011
Journal: J Exp Med
Title: Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets.
Volume: 208
Issue: 10
Pages: 2017-31
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Publication
11536012 | J:115619
First Author: Morita Y
Year: 2001
Journal: Cell Death Differ
Title: Caspase-2 deficiency prevents programmed germ cell death resulting from cytokine insufficiency but not meiotic defects caused by loss of ataxia telangiectasia-mutated (Atm) gene function.
Volume: 8
Issue: 6
Pages: 614-20
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Publication
24095739 | J:203778
First Author: Weinlich R
Year: 2013
Journal: Cell Rep
Title: Protective roles for caspase-8 and cFLIP in adult homeostasis.
Volume: 5
Issue: 2
Pages: 340-8
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Publication
19521510 | J:211458
First Author: Nogueira CV
Year: 2009
Journal: PLoS Pathog
Title: Rapid pathogen-induced apoptosis: a mechanism used by dendritic cells to limit intracellular replication of Legionella pneumophila.
Volume: 5
Issue: 6
Pages: e1000478
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Publication
31944180 | J:290264
   
First Author: Vagnozzi AN
Year: 2020
Journal: Elife
Title: Phrenic-specific transcriptional programs shape respiratory motor output.
Volume: 9
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Publication
30102258 | J:266453
First Author: Feng D
Year: 2018
Journal: J Clin Invest
Title: SNAP23 regulates BAX-dependent adipocyte programmed cell death independently of canonical macroautophagy.
Volume: 128
Issue: 9
Pages: 3941-3956
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Publication
25855178 | J:219627
First Author: Li S
Year: 2015
Journal: J Neurosci
Title: DSCAM promotes refinement in the mouse retina through cell death and restriction of exploring dendrites.
Volume: 35
Issue: 14
Pages: 5640-54
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Publication
15247919 | J:92099
First Author: Moqrich A
Year: 2004
Journal: Nat Neurosci
Title: Expressing TrkC from the TrkA locus causes a subset of dorsal root ganglia neurons to switch fate.
Volume: 7
Issue: 8
Pages: 812-8
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Publication
17553423 | J:126484
First Author: Luo W
Year: 2007
Journal: Neuron
Title: A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons.
Volume: 54
Issue: 5
Pages: 739-54
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Publication
31721194 | J:288269
First Author: Simmons AB
Year: 2020
Journal: J Comp Neurol
Title: Increased density and age-related sharing of synapses at the cone to OFF bipolar cell synapse in the mouse retina.
Volume: 528
Issue: 7
Pages: 1140-1156
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Publication
17209037 | J:120886
First Author: Kang HR
Year: 2007
Journal: J Biol Chem
Title: Transforming growth factor (TGF)-beta1 stimulates pulmonary fibrosis and inflammation via a Bax-dependent, bid-activated pathway that involves matrix metalloproteinase-12.
Volume: 282
Issue: 10
Pages: 7723-32
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Publication
26338970 | J:314981
First Author: Wang Z
Year: 2015
Journal: Oncotarget
Title: Stat5-deficient hematopoiesis is permissive for Myc-induced B-cell leukemogenesis.
Volume: 6
Issue: 30
Pages: 28961-72
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Publication
24200695 | J:207772
First Author: Caganova M
Year: 2013
Journal: J Clin Invest
Title: Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis.
Volume: 123
Issue: 12
Pages: 5009-22
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