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Search results 4301 to 4400 out of 9662 for Egf

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Type Details Score
Publication
9102301 | J:39351
First Author: de la Pompa JL
Year: 1997
Journal: Development
Title: Conservation of the Notch signalling pathway in mammalian neurogenesis.
Volume: 124
Issue: 6
Pages: 1139-48
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Publication
17685488 | J:124179
First Author: Del Monte G
Year: 2007
Journal: Dev Dyn
Title: Monitoring Notch1 activity in development: evidence for a feedback regulatory loop.
Volume: 236
Issue: 9
Pages: 2594-614
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Publication
17849441 | J:125511
First Author: Loomes KM
Year: 2007
Journal: Dev Dyn
Title: Dll3 and Notch1 genetic interactions model axial segmental and craniofacial malformations of human birth defects.
Volume: 236
Issue: 10
Pages: 2943-51
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Publication
26563570 | J:227333
 
First Author: Kofler NM
Year: 2015
Journal: Sci Rep
Title: Combined deficiency of Notch1 and Notch3 causes pericyte dysfunction, models CADASIL, and results in arteriovenous malformations.
Volume: 5
Pages: 16449
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Publication
25744722 | J:220232
First Author: Banerjee D
Year: 2015
Journal: Cancer Res
Title: Notch suppresses angiogenesis and progression of hepatic metastases.
Volume: 75
Issue: 8
Pages: 1592-602
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Publication
14595837 | J:87272
First Author: Krebs LT
Year: 2003
Journal: Genesis
Title: Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutation.
Volume: 37
Issue: 3
Pages: 139-43
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Publication
17460065 | J:121087
First Author: Bjarnadottir M
Year: 2007
Journal: J Neurosci
Title: Neuregulin1 (NRG1) signaling through Fyn modulates NMDA receptor phosphorylation: differential synaptic function in NRG1+/- knock-outs compared with wild-type mice.
Volume: 27
Issue: 17
Pages: 4519-29
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Publication
20651287 | J:175025
First Author: Lai D
Year: 2010
Journal: Circ Res
Title: Neuregulin 1 sustains the gene regulatory network in both trabecular and nontrabecular myocardium.
Volume: 107
Issue: 6
Pages: 715-27
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Publication
20212127 | J:158688
First Author: Seshadri S
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade.
Volume: 107
Issue: 12
Pages: 5622-7
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Publication
28089851 | J:249397
First Author: Schneider S
Year: 2017
Journal: Behav Brain Res
Title: Neuregulin-1 mutant mice indicate motor and sensory deficits, indeed few references for schizophrenia endophenotype model.
Volume: 322
Issue: Pt A
Pages: 177-185
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Allele
Notch2<tm1Grid> | MGI:1933205
Name: notch 2; targeted mutation 1, Tom Gridley
Allele Type: Targeted
Attribute String: Hypomorph
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Publication
24265546 | J:280368
 
First Author: Cottet S
Year: 2013
Journal: Mol Vis
Title: Retinal pigment epithelium protein of 65 kDA gene-linked retinal degeneration is not modulated by chicken acidic leucine-rich epidermal growth factor-like domain containing brain protein/Neuroglycan C/ chondroitin sulfate proteoglycan 5.
Volume: 19
Pages: 2312-20
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Strain
MGI:4439293 | B6.129S1-Jag2<tm1Grid>/J
Attribute String: congenic, mutant strain, targeted mutation
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Publication
9531541 | J:46930
First Author: Jiang R
Year: 1998
Journal: Genes Dev
Title: Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice.
Volume: 12
Issue: 7
Pages: 1046-57
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Publication
37330998 | J:339608
First Author: Mitsiadis TA
Year: 2023
Journal: Cell Mol Life Sci
Title: The Notch-mediated circuitry in the evolution and generation of new cell lineages: the tooth model.
Volume: 80
Issue: 7
Pages: 182
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Publication
16607638 | J:108824
First Author: Casey LM
Year: 2006
Journal: Dev Dyn
Title: Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development.
Volume: 235
Issue: 7
Pages: 1830-44
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Publication
15721140 | J:98508
First Author: Mitsiadis TA
Year: 2005
Journal: Arch Oral Biol
Title: Role of the Notch signalling pathway in tooth morphogenesis.
Volume: 50
Issue: 2
Pages: 137-40
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Publication
20685737 | J:164590
First Author: Mitsiadis TA
Year: 2010
Journal: Development
Title: BMPs and FGFs target Notch signalling via jagged 2 to regulate tooth morphogenesis and cytodifferentiation.
Volume: 137
Issue: 18
Pages: 3025-35
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Publication
18350543 | J:133948
First Author: Worsley AG
Year: 2008
Journal: Eur J Immunol
Title: Dendritic cell expression of the Notch ligand jagged2 is not essential for Th2 response induction in vivo.
Volume: 38
Issue: 4
Pages: 1043-9
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Publication
10080181 | J:53432
First Author: Lanford PJ
Year: 1999
Journal: Nat Genet
Title: Notch signalling pathway mediates hair cell development in mammalian cochlea.
Volume: 21
Issue: 3
Pages: 289-92
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Strain
MGI:5527280 | STOCK Notch3<tm1Grid>/MshaJ
Attribute String: targeted mutation, mutant stock
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Strain
MGI:4439307 | B6;129S1-Notch3<tm1Grid>/J
Attribute String: targeted mutation, mutant stock
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Strain
MGI:5698532 | B6;129S1-Notch3<tm1Grid>/2J
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:2687048 | 129S1/SvImJ-Notch3<tm1Grid>
Attribute String: mutant strain, targeted mutation
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Strain
MGI:7797279 | B6.129S1-Notch3<tm1Grid>
Attribute String: congenic, mutant strain, targeted mutation
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Publication
15545631 | J:94047
First Author: Domenga V
Year: 2004
Journal: Genes Dev
Title: Notch3 is required for arterial identity and maturation of vascular smooth muscle cells.
Volume: 18
Issue: 22
Pages: 2730-5
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Publication
32908186 | J:306657
First Author: López-López S
Year: 2020
Journal: Sci Rep
Title: NOTCH3 signaling is essential for NF-κB activation in TLR-activated macrophages.
Volume: 10
Issue: 1
Pages: 14839
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Publication
25421557 | J:315013
First Author: El Machhour F
Year: 2015
Journal: J Am Soc Nephrol
Title: Activation of Notch3 in Glomeruli Promotes the Development of Rapidly Progressive Renal Disease.
Volume: 26
Issue: 7
Pages: 1561-75
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Publication
18818417 | J:159790
First Author: Belin de Chantemèle EJ
Year: 2008
Journal: Arterioscler Thromb Vasc Biol
Title: Notch3 is a major regulator of vascular tone in cerebral and tail resistance arteries.
Volume: 28
Issue: 12
Pages: 2216-24
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Publication
28108512 | J:239737
First Author: Choy L
Year: 2017
Journal: Cancer Res
Title: Constitutive NOTCH3 Signaling Promotes the Growth of Basal Breast Cancers.
Volume: 77
Issue: 6
Pages: 1439-1452
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Publication
25164209 | J:317772
First Author: Rusanescu G
Year: 2014
Journal: J Cell Mol Med
Title: Notch3 is necessary for neuronal differentiation and maturation in the adult spinal cord.
Volume: 18
Issue: 10
Pages: 2103-16
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Publication
20689064 | J:178201
First Author: Liu H
Year: 2010
Journal: Circ Res
Title: Notch3 is critical for proper angiogenesis and mural cell investment.
Volume: 107
Issue: 7
Pages: 860-70
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Publication
38015629 | J:344395
 
First Author: Romay MC
Year: 2024
Journal: J Clin Invest
Title: Age-related loss of Notch3 underlies brain vascular contractility deficiencies, glymphatic dysfunction, and neurodegeneration in mice.
Volume: 134
Issue: 2
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Publication
25323858 | J:252827
First Author: Zhao N
Year: 2015
Journal: Circ Res
Title: MicroRNA miR145 regulates TGFBR2 expression and matrix synthesis in vascular smooth muscle cells.
Volume: 116
Issue: 1
Pages: 23-34
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Publication
21518968 | J:315137
First Author: Boulos N
Year: 2011
Journal: Hypertension
Title: Notch3 is essential for regulation of the renal vascular tone.
Volume: 57
Issue: 6
Pages: 1176-82
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Publication
19855400 | J:154293
First Author: Li X
Year: 2009
Journal: Nat Med
Title: Notch3 signaling promotes the development of pulmonary arterial hypertension.
Volume: 15
Issue: 11
Pages: 1289-97
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Publication
28131704 | J:325200
 
First Author: Tao YK
Year: 2017
Journal: Int J Cardiol
Title: Notch3 deficiency impairs coronary microvascular maturation and reduces cardiac recovery after myocardial ischemia.
Volume: 236
Pages: 413-422
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Publication
32499639 | J:293917
First Author: Wei K
Year: 2020
Journal: Nature
Title: Notch signalling drives synovial fibroblast identity and arthritis pathology.
Volume: 582
Issue: 7811
Pages: 259-264
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Genotype
Genotype
Symbol: Notch3/Notch3
Background: 129S1/SvImJ-Notch3
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Notch3/Notch3
Background: involves: 129S1/Sv * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Notch1/Notch1 Notch3/Notch3
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Erbb2/Erbb2<+> Nrg1/Nrg1<+>
Background: involves: 129P2/OlaHsd
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Notch2/Notch2
Background: involves: 129S1/Sv * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Jag2/Jag2
Background: involves: 129S1/Sv * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Jag2/Jag2<+>
Background: involves: 129S1/Sv * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Jag2/Jag2 Lfng/Lfng
Background: involves: 129S1/Sv * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Jag2/Jag2 Lfng/Lfng<+>
Background: involves: 129S1/Sv * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nrg1/Nrg1 Isl2/Isl2<+>
Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dll1/Dll1<+> Jag2/Jag2<+>
Background: involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dll1/Dll1<+> Jag2/Jag2
Background: involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Jag2/Jag2
Background: involves: 129S1/Sv * 129S1/SvImJ * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Notch3/Notch3
Background: involves: 129S1/Sv
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Notch3/Notch3
Background: involves: 129S1/Sv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Notch1/Notch1<+> Notch3/Notch3
Background: involves: 129S1/Sv * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Notch2/Notch2<+>
Background: involves: 129S1/Sv * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Notch3/Notch3
Background: B6;129S1-Notch3/J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Notch3/Notch3<+>
Background: B6;129S1-Notch3/J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Notch3/Notch3
Background: B6.129S1-Notch3
Zygosity: hm
Has Mutant Allele: true
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Protein
A0A0J9YTZ3
Organism: Mus musculus/domesticus
Length: 84  
Fragment?: false
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Protein
A0A0A6YW49
Organism: Mus musculus/domesticus
Length: 98  
Fragment?: true
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Publication
2229050 | -
First Author: Lin YZ
Year: 1990
Journal: J Biol Chem
Title: Growth inhibition by vaccinia virus growth factor.
Volume: 265
Issue: 31
Pages: 18884-90
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Protein Domain
IPR015497 | EGF_rcpt_ligand
Type: Family
Description: The mammalian ligands that bind the EGF receptor (EGFR) include EGF, transforming growth factor-alpha (TGFalpha), heparin-binding EGF-like growth factor (HB-EGF), amphiregulin (AR), betacellulin (BTC), epiregulin (EPR), and epigen. Each contains one or more copies of the EGF repeat. The EGF domain includes six cysteine residues, which have been shown (in EGF) to be involved in disulphide bonds. The main structure is a two-stranded β-sheet followed by a loop to a C-terminal short two-stranded sheet. Subdomains between the conserved cysteines vary in length.Interestingly, this entry also includes some epidermal growth factor-like proteins secreted from virus, including pro-vaccinia growth factor from Vaccinia virus [].
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Publication
17010937 | J:116051
First Author: Nanba D
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Loss of HB-EGF in smooth muscle or endothelial cell lineages causes heart malformation.
Volume: 350
Issue: 2
Pages: 315-21
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Publication
1840698 | J:114809
First Author: Higashiyama S
Year: 1991
Journal: Science
Title: A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF.
Volume: 251
Issue: 4996
Pages: 936-9
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Publication
22037761 | J:183678
First Author: Toda S
Year: 2012
Journal: Mol Cell Biol
Title: Two-step engulfment of apoptotic cells.
Volume: 32
Issue: 1
Pages: 118-25
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Genotype
Genotype
Symbol: Celsr3/Celsr3 Emx1/Emx1<+>
Background: involves: 129P2/OlaHsd * 129S2/SvPas
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Celsr1/Celsr1<+> Scrib/Scrib<+> Vangl2/Vangl2<+>
Background: C3H.Cg-Vangl2 Scrib Celsr1
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Apoe/Apoe Svep1/Svep1<+>
Background: involves: 129P2/OlaHsd * C57BL/6N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Celsr1/Celsr1<+> Wnt5a/Wnt5a<+>
Background: involves: 129 * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Celsr1/Celsr1<+> Egr2/Egr2<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Celsr1/Celsr1 Egr2/Egr2<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Publication
21743464 | J:174422
First Author: Devenport D
Year: 2011
Journal: Nat Cell Biol
Title: Mitotic internalization of planar cell polarity proteins preserves tissue polarity.
Volume: 13
Issue: 8
Pages: 893-902
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Publication
29510119 | J:261565
First Author: Stoller ML
Year: 2018
Journal: Dev Biol
Title: Domineering non-autonomy in Vangl1;Vangl2 double mutants demonstrates intercellular PCP signaling in the vertebrate inner ear.
Volume: 437
Issue: 1
Pages: 17-26
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Publication
28705793 | J:269234
First Author: Pujol F
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Dachsous1-Fat4 Signaling Controls Endothelial Cell Polarization During Lymphatic Valve Morphogenesis-Brief Report.
Volume: 37
Issue: 9
Pages: 1732-1735
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Protein
A0A1L1SV90
Organism: Mus musculus/domesticus
Length: 154  
Fragment?: true
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Publication
10781814 | -
First Author: Strasser R
Year: 2000
Journal: FEBS Lett
Title: Molecular cloning and functional expression of beta1, 2-xylosyltransferase cDNA from Arabidopsis thaliana.
Volume: 472
Issue: 1
Pages: 105-8
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Publication
20946875 | -
First Author: Dergai O
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Intersectin 1 forms complexes with SGIP1 and Reps1 in clathrin-coated pits.
Volume: 402
Issue: 2
Pages: 408-13
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Publication
21907823 | -
First Author: Badway JA
Year: 2011
Journal: Int J Biochem Cell Biol
Title: Reps2: a cellular signaling and molecular trafficking nexus.
Volume: 43
Issue: 12
Pages: 1660-3
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Protein Domain
IPR026814 | Reps1
Type: Family
Description: This family includes RalBP1-associated Eps domain-containing protein 1 (REPS1). REPS1 may coordinate the cellular actions of activated EGF receptors and Ral-GTPases []. It is involved in endocytosis [, ].
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Protein Domain
IPR007657 | Glycosyltransferase_61
Type: Family
Description: Glycosyltransferase 61 family members are further processed into a mature form. Proteins in this family includes O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGnT2, also known as EOGTL) []and EGF domain-specific O-linked N-acetylglucosamine transferase (EOGT) []. This entry also includes plant beta-(1,2)-xylosyltransferase [].
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GO Term
GO:1901185 | negative regulation of ERBB signaling pathway
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GO Term
GO:1901186 | positive regulation of ERBB signaling pathway
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GO Term
GO:1905282 | regulation of epidermal growth factor receptor signaling pathway involved in heart process
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Publication
17937400 | J:125765
First Author: Crompton LA
Year: 2007
Journal: Dev Dyn
Title: Early embryonic expression patterns of the mouse Flamingo and Prickle orthologues.
Volume: 236
Issue: 11
Pages: 3137-43
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HT Experiment
GSE175835 | Granulosa cell mevalonate pathway abnormalities contribute to oocyte meiotic defects and aneuploidy [RNA-seq mouse oocyte]
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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HT Experiment
GSE181527 | The Heterogeneous Nuclear Ribonucleoprotein U (HNRNPU) is the Safeguard of Neural Stem Cell Viability
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE175834 | Granulosa cell mevalonate pathway abnormalities contribute to oocyte meiotic defects and aneuploidy [RNA-seq mouse GC]
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
10330372 | J:54606
First Author: Barrantes IB
Year: 1999
Journal: Curr Biol
Title: Interaction between Notch signalling and Lunatic fringe during somite boundary formation in the mouse.
Volume: 9
Issue: 9
Pages: 470-80
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Publication
23087364 | J:264438
First Author: Hans CP
Year: 2012
Journal: Arterioscler Thromb Vasc Biol
Title: Inhibition of Notch1 signaling reduces abdominal aortic aneurysm in mice by attenuating macrophage-mediated inflammation.
Volume: 32
Issue: 12
Pages: 3012-23
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Publication
34504875 | J:310848
 
First Author: Matos-Nieves A
Year: 2021
Journal: Front Cardiovasc Med
Title: A Multi-Omics Approach Using a Mouse Model of Cardiac Malformations for Prioritization of Human Congenital Heart Disease Contributing Genes.
Volume: 8
Pages: 683074
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Publication
23583836 | J:261847
 
First Author: Bosse K
Year: 2013
Journal: J Mol Cell Cardiol
Title: Endothelial nitric oxide signaling regulates Notch1 in aortic valve disease.
Volume: 60
Pages: 27-35
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Publication
16699526 | J:112675
First Author: Visan I
Year: 2006
Journal: Nat Immunol
Title: Regulation of T lymphopoiesis by Notch1 and Lunatic fringe-mediated competition for intrathymic niches.
Volume: 7
Issue: 6
Pages: 634-43
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Publication
10879540 | J:62882
First Author: Huppert SS
Year: 2000
Journal: Nature
Title: Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1.
Volume: 405
Issue: 6789
Pages: 966-70
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Publication
20346184 | J:160476
 
First Author: Ge C
Year: 2010
Journal: BMC Dev Biol
Title: Effects of varying Notch1 signal strength on embryogenesis and vasculogenesis in compound mutant heterozygotes.
Volume: 10
Pages: 36
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Publication
26023079 | J:241812
First Author: Chen J
Year: 2015
Journal: Arterioscler Thromb Vasc Biol
Title: Notch1 Mutation Leads to Valvular Calcification Through Enhanced Myofibroblast Mechanotransduction.
Volume: 35
Issue: 7
Pages: 1597-605
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Publication
10837254 | J:62727
First Author: Zhang N
Year: 2000
Journal: Curr Biol
Title: A mutation in the Lunatic fringe gene suppresses the effects of a Jagged2 mutation on inner hair cell development in the cochlea.
Volume: 10
Issue: 11
Pages: 659-62
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Publication
17948123 | J:127386
First Author: Shawber CJ
Year: 2007
Journal: J Clin Invest
Title: Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression.
Volume: 117
Issue: 11
Pages: 3369-82
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Strain
MGI:4867442 | B6.129S1-Notch2<tm1Grid>/J
Attribute String: congenic, mutant strain, targeted mutation
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Publication
28322273 | J:301708
First Author: Yan L
Year: 2018
Journal: Mol Psychiatry
Title: Neuregulin-2 ablation results in dopamine dysregulation and severe behavioral phenotypes relevant to psychiatric disorders.
Volume: 23
Issue: 5
Pages: 1233-1243
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Publication
33493092 | J:323987
First Author: Vera L
Year: 2021
Journal: Am J Respir Cell Mol Biol
Title: Notch3 Deficiency Attenuates Pulmonary Fibrosis and Impedes Lung-Function Decline.
Volume: 64
Issue: 4
Pages: 465-476
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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