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Search results 4301 to 4400 out of 4540 for Nanog

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Type Details Score
Allele  
Name: Nanog homeobox; gene trap OST241001, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: Nanog homeobox; gene trap OST258068, Lexicon Genetics
Allele Type: Gene trapped
Allele
Name: Nanog homeobox; targeted mutation 1, Konrad Hochedlinger
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: Nanog homeobox; targeted mutation 3, Antonio Simeone
Allele Type: Targeted
Attribute String: Not Specified
Allele
Name: Nanog homeobox; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Publication
First Author: Carey TS
Year: 2015
Journal: Mol Cell Biol
Title: BRG1 Governs Nanog Transcription in Early Mouse Embryos and Embryonic Stem Cells via Antagonism of Histone H3 Lysine 9/14 Acetylation.
Volume: 35
Issue: 24
Pages: 4158-69
Interaction Experiment
Description: Zfp143 regulates Nanog through modulation of Oct4 binding.
Interaction Experiment
Description: Phosphorylation stabilizes Nanog by promoting its interaction with Pin1.
Publication
First Author: De Kumar B
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Dynamic regulation of Nanog and stem cell-signaling pathways by Hoxa1 during early neuro-ectodermal differentiation of ES cells.
Volume: 114
Issue: 23
Pages: 5838-5845
GXD Expression
Probe: MGI:5912154
Assay Type: Immunohistochemistry
Annotation Date: 2022-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Pattern: Regionally restricted
Stage: TS05
Assay Id: MGI:7316604
Age: embryonic day 3.5
Image: S1C',C''
Note: Co-expression with Nanog in some cells; mostly mutually exclusive expression.
Specimen Label: S1C',C''
Detected: true
Specimen Num: 2
Genotype
Symbol: Nanog/Nanog<+>
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: macaque, rhesus
Strain
Attribute String: mutant stock, targeted mutation
Allele  
Name: Nanog homeobox; gene trap PST13394, Mammalian Functional Genomics Centre
Allele Type: Gene trapped
Allele  
Name: Nanog homeobox; gene trap PST13912, Mammalian Functional Genomics Centre
Allele Type: Gene trapped
Allele  
Name: Nanog homeobox; gene trap P025G09, German Gene Trap Consortium
Allele Type: Gene trapped
Allele
Name: Nanog homeobox; gene trap D047A12, German Gene Trap Consortium
Allele Type: Gene trapped
Attribute String: Null/knockout, Reporter
Allele
Name: Nanog homeobox; gene trap D042B07, German Gene Trap Consortium
Allele Type: Gene trapped
Attribute String: Null/knockout, Reporter
Allele  
Name: Nanog homeobox; gene trap D030H07, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: Nanog homeobox; gene trap E194A02, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: Nanog homeobox; gene trap PST7202, Mammalian Functional Genomics Centre
Allele Type: Gene trapped
Allele  
Name: Nanog homeobox; gene trap PST7203, Mammalian Functional Genomics Centre
Allele Type: Gene trapped
Strain
Attribute String: mutant stock, targeted mutation
Allele
Name: Nanog homeobox; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
Allele
Name: Nanog homeobox; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Strain
Attribute String: mutant stock, targeted mutation
Allele
Name: Nanog homeobox; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Allele
Name: Nanog homeobox; endonuclease-mediated mutation 34, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Allele
Name: Nanog homeobox; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Reporter
Genotype
Symbol: Nanog/Nanog
Background: involves: 129S4/SvJae
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Nanog/Nanog
Background: involves: 129 * C57BL/6 * CD-1
Zygosity: hm
Has Mutant Allele: true
Interaction Experiment
Description: Estrogen-related receptor beta interacts with Oct4 to positively regulate Nanog gene expression.
Interaction Experiment
Description: Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells.
Interaction Experiment
Description: Nanog maintains pluripotency of mouse embryonic stem cells by inhibiting NFkappaB and cooperating with Stat3.
Interaction Experiment
Description: A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.
Interaction Experiment
Description: ERK1 phosphorylates Nanog to regulate protein stability and stem cell self-renewal.
Interaction Experiment
Description: USP21 deubiquitylates Nanog to regulate protein stability and stem cell pluripotency.
Interaction Experiment
Description: AMPK Promotes SPOP-Mediated NANOG Degradation to Regulate Prostate Cancer Cell Stemness.
Allele  
Name: Nanog homeobox; gene trap IST14459G9, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: Nanog homeobox; gene trap IST14793A8, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Strain
Attribute String: coisogenic, mutant strain, targeted mutation
Genotype
Symbol: Nanog/Nanog
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Nanog/Nanog
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Shi W
Year: 2006
Journal: J Biol Chem
Title: Regulation of the pluripotency marker Rex-1 by Nanog and Sox2.
Volume: 281
Issue: 33
Pages: 23319-25
Publication
First Author: Chen X
Year: 2008
Journal: Stem Cells
Title: Zfp143 regulates Nanog through modulation of Oct4 binding.
Volume: 26
Issue: 11
Pages: 2759-67
Allele
Name: transgene insertion 2, Atsushi Suzuki
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: regulatory region 384; endonuclease-mediated mutation 1, Sridhar Rao
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
Allele
Name: regulatory region 385; endonuclease-mediated mutation 1, Sridhar Rao
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
Strain
Attribute String: transgenic, mutant strain, congenic
Strain
Attribute String: mutant strain, coisogenic, targeted mutation
Genotype
Symbol: Nanog/Nanog<+>
Background: involves: 129S4/SvJae
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Nanog/Nanog<+>
Background: involves: 129 * C57BL/6 * CD-1
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Nanog/Nanog<+>
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Kim SH
Year: 2014
Journal: Stem Cell Res
Title: ERK1 phosphorylates Nanog to regulate protein stability and stem cell self-renewal.
Volume: 13
Issue: 1
Pages: 1-11
Publication  
First Author: Liu X
Year: 2016
Journal: Signal Transduct Target Ther
Title: USP21 deubiquitylates Nanog to regulate protein stability and stem cell pluripotency.
Volume: 1
Pages: 16024
Publication
First Author: Wang X
Year: 2019
Journal: Dev Cell
Title: AMPK Promotes SPOP-Mediated NANOG Degradation to Regulate Prostate Cancer Cell Stemness.
Volume: 48
Issue: 3
Pages: 345-360.e7
Genotype
Symbol: Nanog/Nanog
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Nanog/Nanog Pou5f1/Pou5f1
Background: involves: 129 * C57BL/6 * CD-1
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Das B
Year: 2019
Journal: Cancer Res
Title: MYC Regulates the HIF2α Stemness Pathway via Nanog and Sox2 to Maintain Self-Renewal in Cancer Stem Cells versus Non-Stem Cancer Cells.
Volume: 79
Issue: 16
Pages: 4015-4025
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160414
Pattern: Non-Uniform
Stage: TS04
Assay Id: MGI:6286316
Age: embryonic day 3.75
Image: 3A 89c
Note: Expression increased as blastocysts developed. Expression in the inner cell mass (ICM) was heterogenous. Embryos were stained for Nanog and Gata6 to identify the epiblast (Nanog+), extraembryonic primitive endoderm (Gata6+), double positive, and double negative cell populations.
Specimen Label: 3A 89c
Detected: true
Specimen Num: 4
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Pattern: Non-Uniform
Stage: TS05
Assay Id: MGI:6286316
Age: embryonic day 4.0
Image: 3A 106c
Note: Expression increased as blastocysts developed. Expression in the inner cell mass (ICM) was heterogenous. Embryos were stained for Nanog and Gata6 to identify the epiblast (Nanog+), extraembryonic primitive endoderm (Gata6+), double positive, and double negative cell populations.
Specimen Label: 3A 106c
Detected: true
Specimen Num: 5
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Pattern: Non-Uniform
Stage: TS05
Assay Id: MGI:6286316
Age: embryonic day 4.5
Image: 3A 148c
Note: Expression increased as blastocysts developed. Expression in the inner cell mass (ICM) was heterogenous. Embryos were stained for Nanog and Gata6 to identify the epiblast (Nanog+), extraembryonic primitive endoderm (Gata6+), double positive, and double negative cell populations.
Specimen Label: 3A 148c
Detected: true
Specimen Num: 6
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Pattern: Non-Uniform
Stage: TS05
Assay Id: MGI:6286316
Age: embryonic day 5.0
Image: 3A 187c
Note: Expression increased as blastocysts developed. Expression in the inner cell mass (ICM) was heterogenous. Embryos were stained for Nanog and Gata6 to identify the epiblast (Nanog+), extraembryonic primitive endoderm (Gata6+), double positive, and double negative cell populations.
Specimen Label: 3A 187c
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:4461245
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160414
Pattern: Non-Uniform
Stage: TS04
Assay Id: MGI:6286338
Age: embryonic day 3.5
Image: 3B 57c
Note: Expression increased as blastocysts developed. Expression in the inner cell mass (ICM) was heterogenous. Embryos were stained for Nanog and Gata6 to identify the epiblast (Nanog+), extraembryonic primitive endoderm (Gata6+), double positive, and double negative cell populations.
Specimen Label: 3B 57c
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4461245
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160414
Pattern: Non-Uniform
Stage: TS04
Assay Id: MGI:6286338
Age: embryonic day 3.75
Image: 3B 86c
Note: Expression increased as blastocysts developed. Expression in the inner cell mass (ICM) was heterogenous. Embryos were stained for Nanog and Gata6 to identify the epiblast (Nanog+), extraembryonic primitive endoderm (Gata6+), double positive, and double negative cell populations.
Specimen Label: 3B 86c
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:4461245
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Pattern: Non-Uniform
Stage: TS05
Assay Id: MGI:6286338
Age: embryonic day 4.0
Image: 3B 91c
Note: Expression increased as blastocysts developed. Expression in the inner cell mass (ICM) was heterogenous. Embryos were stained for Nanog and Gata6 to identify the epiblast (Nanog+), extraembryonic primitive endoderm (Gata6+), double positive, and double negative cell populations.
Specimen Label: 3B 91c
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:4461245
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Pattern: Non-Uniform
Stage: TS05
Assay Id: MGI:6286338
Age: embryonic day 4.5
Image: 3B 141c
Note: Expression increased as blastocysts developed. Expression in the inner cell mass (ICM) was heterogenous. Embryos were stained for Nanog and Gata6 to identify the epiblast (Nanog+), extraembryonic primitive endoderm (Gata6+), double positive, and double negative cell populations.
Specimen Label: 3B 141c
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:4461245
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Pattern: Non-Uniform
Stage: TS05
Assay Id: MGI:6286338
Age: embryonic day 5.0
Image: 3B 159c
Note: Expression increased as blastocysts developed. Expression in the inner cell mass (ICM) was heterogenous. Embryos were stained for Nanog and Gata6 to identify the epiblast (Nanog+), extraembryonic primitive endoderm (Gata6+), double positive, and double negative cell populations.
Specimen Label: 3B 159c
Detected: true
Specimen Num: 7
Publication
First Author: Nimura K
Year: 2009
Journal: Nature
Title: A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome.
Volume: 460
Issue: 7252
Pages: 287-91
Regulatory Region
Type: enhancer
Organism: mouse, laboratory
Regulatory Region
Type: enhancer
Organism: mouse, laboratory
Regulatory Region
Type: enhancer
Organism: mouse, laboratory
Regulatory Region
Type: promoter
Organism: mouse, laboratory
Allele
Name: transgene insertion, Peter Hohenstein
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion 38, Anna-Katerina Hadjantonakis
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion 4470, Michael Shen
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Strain
Attribute String: mutant stock, transgenic
Allele
Name: collagen, type I, alpha 1; targeted mutation 6, Konrad Hochedlinger
Allele Type: Targeted
Attribute String: Inducible, Inserted expressed sequence
Strain
Attribute String: coisogenic, mutant strain, transgenic