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Search results 4301 to 4400 out of 5729 for Nlrp3

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Type Details Score
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Nixon JC
Year: 2004
Journal: J Biol Chem
Title: Mutations in the DNA-binding domain of the transcription factor Bright act as dominant negative proteins and interfere with immunoglobulin transactivation.
Volume: 279
Issue: 50
Pages: 52465-72
Publication
First Author: Yamada N
Year: 1993
Journal: Biochem Biophys Res Commun
Title: Structure and expression of novel protein-tyrosine kinases, Emb and Emt, in hematopoietic cells.
Volume: 192
Issue: 1
Pages: 231-40
Publication
First Author: Fujino T
Year: 2001
Journal: J Biol Chem
Title: Acetyl-CoA synthetase 2, a mitochondrial matrix enzyme involved in the oxidation of acetate.
Volume: 276
Issue: 14
Pages: 11420-6
Publication
First Author: Patterson HC
Year: 2006
Journal: Immunity
Title: The B cell receptor promotes B cell activation and proliferation through a non-ITAM tyrosine in the Igalpha cytoplasmic domain.
Volume: 25
Issue: 1
Pages: 55-65
Publication
First Author: Kim GW
Year: 2013
Journal: J Biol Chem
Title: Mice lacking α-tubulin acetyltransferase 1 are viable but display α-tubulin acetylation deficiency and dentate gyrus distortion.
Volume: 288
Issue: 28
Pages: 20334-50
Publication
First Author: Brock VJ
Year: 2022
Journal: Sci Adv
Title: P2X4 and P2X7 are essential players in basal T cell activity and Ca2+ signaling milliseconds after T cell activation.
Volume: 8
Issue: 5
Pages: eabl9770
Publication
First Author: Matthews SA
Year: 2010
Journal: Biochem J
Title: Unique functions for protein kinase D1 and protein kinase D2 in mammalian cells.
Volume: 432
Issue: 1
Pages: 153-63
Publication
First Author: Sumara G
Year: 2009
Journal: Cell
Title: Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasis.
Volume: 136
Issue: 2
Pages: 235-48
Publication
First Author: Tsai SH
Year: 2015
Journal: Immunity
Title: The ectoenzyme E-NPP3 negatively regulates ATP-dependent chronic allergic responses by basophils and mast cells.
Volume: 42
Issue: 2
Pages: 279-293
Publication
First Author: Smith JB
Year: 2002
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Glucocorticoid-attenuated response genes induced in the lung during endotoxemia.
Volume: 283
Issue: 3
Pages: L636-47
Publication
First Author: Schmidt U
Year: 2009
Journal: Eur J Immunol
Title: The protein tyrosine kinase Tec regulates mast cell function.
Volume: 39
Issue: 11
Pages: 3228-38
Publication
First Author: Daws MR
Year: 2001
Journal: Eur J Immunol
Title: Cloning and characterization of a novel mouse myeloid DAP12-associated receptor family.
Volume: 31
Issue: 3
Pages: 783-91
Publication
First Author: Kleinberger G
Year: 2014
Journal: Sci Transl Med
Title: TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis.
Volume: 6
Issue: 243
Pages: 243ra86
Publication
First Author: Ulland TK
Year: 2017
Journal: Cell
Title: TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease.
Volume: 170
Issue: 4
Pages: 649-663.e13
Publication
First Author: Kleinberger G
Year: 2017
Journal: EMBO J
Title: The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.
Volume: 36
Issue: 13
Pages: 1837-1853
Publication
First Author: Thornton P
Year: 2017
Journal: EMBO Mol Med
Title: TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer's disease-associated H157Y variant.
Volume: 9
Issue: 10
Pages: 1366-1378
Publication
First Author: Zheng H
Year: 2017
Journal: J Neurosci
Title: TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway.
Volume: 37
Issue: 7
Pages: 1772-1784
Publication
First Author: Wu R
Year: 2017
Journal: Mol Brain
Title: TREM2 protects against cerebral ischemia/reperfusion injury.
Volume: 10
Issue: 1
Pages: 20
Publication
First Author: Filipello F
Year: 2018
Journal: Immunity
Title: The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity.
Volume: 48
Issue: 5
Pages: 979-991.e8
Publication
First Author: Sudom A
Year: 2018
Journal: J Biol Chem
Title: Molecular basis for the loss-of-function effects of the Alzheimer's disease-associated R47H variant of the immune receptor TREM2.
Volume: 293
Issue: 32
Pages: 12634-12646
Publication
First Author: Cheng-Hathaway PJ
Year: 2018
Journal: Mol Neurodegener
Title: The Trem2 R47H variant confers loss-of-function-like phenotypes in Alzheimer's disease.
Volume: 13
Issue: 1
Pages: 29
Publication
First Author: Li C
Year: 2019
Journal: Cell Biol Int
Title: TREM2 inhibits inflammatory responses in mouse microglia by suppressing the PI3K/NF-κB signaling.
Volume: 43
Issue: 4
Pages: 360-372
Publication
First Author: Linnartz-Gerlach B
Year: 2019
Journal: Glia
Title: TREM2 triggers microglial density and age-related neuronal loss.
Volume: 67
Issue: 3
Pages: 539-550
Publication
First Author: Kikuchi Y
Year: 2000
Journal: Int Immunol
Title: Identification and characterization of a molecule, BAM11, that associates with the pleckstrin homology domain of mouse Btk.
Volume: 12
Issue: 10
Pages: 1397-408
Publication
First Author: Wang YP
Year: 2014
Journal: EMBO J
Title: Regulation of G6PD acetylation by SIRT2 and KAT9 modulates NADPH homeostasis and cell survival during oxidative stress.
Volume: 33
Issue: 12
Pages: 1304-20
Publication
First Author: Yao L
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C.
Volume: 91
Issue: 19
Pages: 9175-9
Publication
First Author: Waggie KS
Year: 1992
Journal: Lab Anim Sci
Title: Lymphoblastic lymphoma in a colony of N:NIH(S)-bg-nu-xid mice.
Volume: 42
Issue: 4
Pages: 375-7
Publication
First Author: Abraham D
Year: 2004
Journal: Infect Immun
Title: Immunoglobulin E and eosinophil-dependent protective immunity to larval Onchocerca volvulus in mice immunized with irradiated larvae.
Volume: 72
Issue: 2
Pages: 810-7
Publication
First Author: Won WJ
Year: 2006
Journal: J Immunol
Title: Fc receptor homolog 3 is a novel immunoregulatory marker of marginal zone and B1 B cells.
Volume: 177
Issue: 10
Pages: 6815-23
Publication
First Author: Ren L
Year: 2016
Journal: J Biol Chem
Title: Analysis of the Effects of the Bruton's tyrosine kinase (Btk) Inhibitor Ibrutinib on Monocyte Fcγ Receptor (FcγR) Function.
Volume: 291
Issue: 6
Pages: 3043-52
Publication
First Author: Lee KG
Year: 2015
Journal: Cell Rep
Title: Bruton's tyrosine kinase phosphorylates DDX41 and activates its binding of dsDNA and STING to initiate type 1 interferon response.
Volume: 10
Issue: 7
Pages: 1055-65
Publication
First Author: Hoerauf A
Year: 1995
Journal: Int Immunol
Title: Effect of IL-7 treatment on Leishmania major-infected BALB.Xid mice: enhanced lymphopoiesis with sustained lack of B1 cells and clinical aggravation of disease.
Volume: 7
Issue: 11
Pages: 1879-84
Publication
First Author: Schubart DB
Year: 2000
Journal: J Immunol
Title: Cutting edge: lack of peripheral B cells and severe agammaglobulinemia in mice simultaneously lacking Bruton's tyrosine kinase and the B cell-specific transcriptional coactivator OBF-1.
Volume: 164
Issue: 1
Pages: 18-22
Publication
First Author: Itakura A
Year: 2005
Journal: J Immunol
Title: An hour after immunization peritoneal B-1 cells are activated to migrate to lymphoid organs where within 1 day they produce IgM antibodies that initiate elicitation of contact sensitivity.
Volume: 175
Issue: 11
Pages: 7170-8
Publication
First Author: Wu P
Year: 1994
Journal: Cell Immunol
Title: The secondary B cell lineage for phosphorylcholine is conserved in CBA/CaHN-xid/J mice.
Volume: 155
Issue: 2
Pages: 345-57
Publication
First Author: Westerberg LS
Year: 2008
Journal: Blood
Title: WASP confers selective advantage for specific hematopoietic cell populations and serves a unique role in marginal zone B-cell homeostasis and function.
Volume: 112
Issue: 10
Pages: 4139-47
Publication
First Author: Santos-Argumedo L
Year: 1995
Journal: Int Immunol
Title: CD38 unresponsiveness of xid B cells implicates Bruton's tyrosine kinase (btk) as a regular of CD38 induced signal transduction.
Volume: 7
Issue: 2
Pages: 163-70
Publication
First Author: Rodríguez-Alba JC
Year: 2008
Journal: Blood
Title: CD38 induces differentiation of immature transitional 2 B lymphocytes in the spleen.
Volume: 111
Issue: 7
Pages: 3644-52
Publication  
First Author: Avriyanti E
Year: 2015
Journal: Neurosci Res
Title: Functional redundancy of protein kinase D1 and protein kinase D2 in neuronal polarity.
Volume: 95
Pages: 12-20
Publication
First Author: Yu PW
Year: 2004
Journal: Blood
Title: Sustained correction of B-cell development and function in a murine model of X-linked agammaglobulinemia (XLA) using retroviral-mediated gene transfer.
Volume: 104
Issue: 5
Pages: 1281-90
Publication
First Author: Forssell J
Year: 2005
Journal: Am J Respir Cell Mol Biol
Title: Interleukin-2-inducible T cell kinase regulates mast cell degranulation and acute allergic responses.
Volume: 32
Issue: 6
Pages: 511-20
Publication
First Author: Ellmeier W
Year: 2000
Journal: J Exp Med
Title: Severe B cell deficiency in mice lacking the tec kinase family members Tec and Btk.
Volume: 192
Issue: 11
Pages: 1611-24
Publication
First Author: Nyhoff LE
Year: 2018
Journal: J Immunol
Title: Bruton's Tyrosine Kinase Is Not Essential for B Cell Survival beyond Early Developmental Stages.
Volume: 200
Issue: 7
Pages: 2352-2361
Publication
First Author: Ormsby T
Year: 2011
Journal: Blood
Title: Btk is a positive regulator in the TREM-1/DAP12 signaling pathway.
Volume: 118
Issue: 4
Pages: 936-45
Publication
First Author: Oldham AL
Year: 2011
Journal: Mol Immunol
Title: The transcription factor Bright plays a role in marginal zone B lymphocyte development and autoantibody production.
Volume: 49
Issue: 1-2
Pages: 367-79
Publication
First Author: Katlinskaya YV
Year: 2016
Journal: Mol Cell Biol
Title: Type I Interferons Control Proliferation and Function of the Intestinal Epithelium.
Volume: 36
Issue: 7
Pages: 1124-35
Publication  
First Author: Snyder JD
Year: 2024
Journal: Front Immunol
Title: Protein kinase D1 in myeloid lineage cells contributes to the accumulation of CXCR3(+)CCR6(+) nonconventional Th1 cells in the lungs and potentiates hypersensitivity pneumonitis caused by S. rectivirgula.
Volume: 15
Pages: 1403155
Publication
First Author: Chen P
Year: 2024
Journal: Clin Transl Med
Title: Neutrophil pyroptosis regulates corneal wound healing and post-injury neovascularisation.
Volume: 14
Issue: 11
Pages: e1762
Publication
First Author: Hu Y
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: The Gasdermin D N-terminal fragment acts as a negative feedback system to inhibit inflammasome-mediated activation of Caspase-1/11.
Volume: 119
Issue: 45
Pages: e2210809119
Publication  
First Author: Sa de Almeida J
Year: 2020
Journal: Front Neurosci
Title: Microglial Sirtuin 2 Shapes Long-Term Potentiation in Hippocampal Slices.
Volume: 14
Pages: 614
Publication
First Author: Cicko S
Year: 2018
Journal: Oncotarget
Title: Extracellular ATP is a danger signal activating P2X7 receptor in a LPS mediated inflammation (ARDS/ALI).
Volume: 9
Issue: 55
Pages: 30635-30648
Publication
First Author: Xing J
Year: 2021
Journal: Nat Commun
Title: Identification of poly(ADP-ribose) polymerase 9 (PARP9) as a noncanonical sensor for RNA virus in dendritic cells.
Volume: 12
Issue: 1
Pages: 2681
Publication
First Author: Monteleone M
Year: 2018
Journal: Cell Rep
Title: Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion.
Volume: 24
Issue: 6
Pages: 1425-1433
Publication
First Author: Wang Z
Year: 2020
Journal: J Immunol
Title: Zebrafish GSDMEb Cleavage-Gated Pyroptosis Drives Septic Acute Kidney Injury In Vivo.
Volume: 204
Issue: 7
Pages: 1929-1942
Publication
First Author: Lu Y
Year: 2019
Journal: Nat Commun
Title: Caspase-11 signaling enhances graft-versus-host disease.
Volume: 10
Issue: 1
Pages: 4044
Publication
First Author: Estfanous S
Year: 2021
Journal: Sci Rep
Title: Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo.
Volume: 11
Issue: 1
Pages: 855
Publication      
First Author: Eltobgy M
Year: 2021
Journal: bioRxiv
Title: Caspase-4/11 exacerbates disease severity in SARS-CoV-2 infection by promoting inflammation and thrombosis.
Publication
First Author: Eltobgy MM
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Caspase-4/11 exacerbates disease severity in SARS-CoV-2 infection by promoting inflammation and immunothrombosis.
Volume: 119
Issue: 21
Pages: e2202012119
Publication
First Author: Ribezzo F
Year: 2019
Journal: Leukemia
Title: Rps14, Csnk1a1 and miRNA145/miRNA146a deficiency cooperate in the clinical phenotype and activation of the innate immune system in the 5q- syndrome.
Volume: 33
Issue: 7
Pages: 1759-1772
Publication
First Author: Kraemer FB
Year: 2004
Journal: Mol Endocrinol
Title: Hormone-sensitive lipase is required for high-density lipoprotein cholesteryl ester-supported adrenal steroidogenesis.
Volume: 18
Issue: 3
Pages: 549-57
Publication
First Author: Xie J
Year: 2023
Journal: Eur J Immunol
Title: GSDMD-mediated NETosis promotes the development of acute respiratory distress syndrome.
Volume: 53
Issue: 1
Pages: e2250011
Publication
First Author: Keren-Shaul H
Year: 2017
Journal: Cell
Title: A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.
Volume: 169
Issue: 7
Pages: 1276-1290.e17
Publication  
First Author: Messemer N
Year: 2013
Journal: Neuropharmacology
Title: P2X7 receptors at adult neural progenitor cells of the mouse subventricular zone.
Volume: 73
Pages: 122-37
Publication  
First Author: Brock VJ
Year: 2024
Journal: Front Immunol
Title: Time-resolved role of P2X4 and P2X7 during CD8(+) T cell activation.
Volume: 15
Pages: 1258119
Publication
First Author: Behr FM
Year: 2020
Journal: Nat Immunol
Title: Tissue-resident memory CD8+ T cells shape local and systemic secondary T cell responses.
Volume: 21
Issue: 9
Pages: 1070-1081
Publication
First Author: Ebeling G
Year: 2014
Journal: PLoS One
Title: Effect of P2X7 receptor knockout on AQP-5 expression of type I alveolar epithelial cells.
Volume: 9
Issue: 6
Pages: e100282
Publication
First Author: Heiss K
Year: 2008
Journal: J Immunol
Title: High sensitivity of intestinal CD8+ T cells to nucleotides indicates P2X7 as a regulator for intestinal T cell responses.
Volume: 181
Issue: 6
Pages: 3861-9
Publication
First Author: Kawamura H
Year: 2012
Journal: Immunology
Title: Extracellular ATP-stimulated macrophages produce macrophage inflammatory protein-2 which is important for neutrophil migration.
Volume: 136
Issue: 4
Pages: 448-58
Publication
First Author: Yoshida K
Year: 2020
Journal: J Immunol
Title: Extracellular ATP Augments Antigen-Induced Murine Mast Cell Degranulation and Allergic Responses via P2X4 Receptor Activation.
Volume: 204
Issue: 12
Pages: 3077-3085
Publication
First Author: Stoiljkovic M
Year: 2022
Journal: J Alzheimers Dis
Title: TREM2 Deficiency Disrupts Network Oscillations Leading to Epileptic Activity and Aggravates Amyloid-β-Related Hippocampal Pathophysiology in Mice.
Volume: 88
Issue: 3
Pages: 837-847
Publication  
First Author: Wu Y
Year: 2021
Journal: J Clin Invest
Title: TREM-2 promotes Th1 responses by interacting with the CD3ζ-ZAP70 complex following Mycobacterium tuberculosis infection.
Volume: 131
Issue: 17
Publication
First Author: Qu S
Year: 2024
Journal: Neurosci Bull
Title: TREM-2 Drives Development of Multiple Sclerosis by Promoting Pathogenic Th17 Polarization.
Volume: 40
Issue: 1
Pages: 17-34
Publication
First Author: Liao Y
Year: 2023
Journal: EMBO J
Title: The Ras GTPase-activating-like protein IQGAP1 bridges Gasdermin D to the ESCRT system to promote IL-1β release via exosomes.
Volume: 42
Issue: 1
Pages: e110780
Publication
First Author: Dhandapani R
Year: 2022
Journal: Cell Rep
Title: Sustained Trem2 stabilization accelerates microglia heterogeneity and Aβ pathology in a mouse model of Alzheimer's disease.
Volume: 39
Issue: 9
Pages: 110883
Publication
First Author: de Bruijn MJ
Year: 2017
Journal: J Immunol
Title: Distinct and Overlapping Functions of TEC Kinase and BTK in B Cell Receptor Signaling.
Volume: 198
Issue: 8
Pages: 3058-3068
Publication
First Author: Dejanovic B
Year: 2022
Journal: Nat Aging
Title: Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer's disease mouse models.
Volume: 2
Issue: 9
Pages: 837-850
Publication
First Author: Lee SH
Year: 2021
Journal: Neuron
Title: Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology.
Volume: 109
Issue: 8
Pages: 1283-1301.e6
Publication
First Author: Lee SH
Year: 2021
Journal: Cell Rep
Title: TREM2-independent oligodendrocyte, astrocyte, and T cell responses to tau and amyloid pathology in mouse models of Alzheimer disease.
Volume: 37
Issue: 13
Pages: 110158
Publication
First Author: Shoji M
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Type-I IFN signaling is required for the induction of antigen-specific CD8(+) T cell responses by adenovirus vector vaccine in the gut-mucosa.
Volume: 425
Issue: 1
Pages: 89-93
Publication
First Author: Ma F
Year: 2024
Journal: Nat Commun
Title: Gasdermin E dictates inflammatory responses by controlling the mode of neutrophil death.
Volume: 15
Issue: 1
Pages: 386
Publication
First Author: Varese A
Year: 2022
Journal: PLoS Pathog
Title: Type I interferons and MAVS signaling are necessary for tissue resident memory CD8+ T cell responses to RSV infection.
Volume: 18
Issue: 2
Pages: e1010272
Publication
First Author: Kumar H
Year: 2008
Journal: J Immunol
Title: Cutting edge: cooperation of IPS-1- and TRIF-dependent pathways in poly IC-enhanced antibody production and cytotoxic T cell responses.
Volume: 180
Issue: 2
Pages: 683-7
Publication
First Author: Kandasamy M
Year: 2016
Journal: PLoS Pathog
Title: RIG-I Signaling Is Critical for Efficient Polyfunctional T Cell Responses during Influenza Virus Infection.
Volume: 12
Issue: 7
Pages: e1005754
Publication
First Author: Eberle F
Year: 2009
Journal: Eur J Immunol
Title: Bacterial RNA is recognized by different sets of immunoreceptors.
Volume: 39
Issue: 9
Pages: 2537-47