|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 4401 to 4500 out of 4757 for Apoe

0.132s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: endonuclease-mediated mutation, mutant strain, targeted mutation, congenic
Publication
First Author: Hendrikx JJ
Year: 2013
Journal: Int J Cancer
Title: P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel.
Volume: 132
Issue: 10
Pages: 2439-47
Publication
First Author: van Waterschoot RA
Year: 2009
Journal: FASEB J
Title: Intestinal cytochrome P450 3A plays an important role in the regulation of detoxifying systems in the liver.
Volume: 23
Issue: 1
Pages: 224-31
Strain
Attribute String: mutant strain, congenic, targeted mutation, transgenic
Publication
First Author: Kirchner H
Year: 2009
Journal: Nat Med
Title: GOAT links dietary lipids with the endocrine control of energy balance.
Volume: 15
Issue: 7
Pages: 741-5
Publication
First Author: van de Steeg E
Year: 2013
Journal: Clin Cancer Res
Title: Influence of human OATP1B1, OATP1B3, and OATP1A2 on the pharmacokinetics of methotrexate and paclitaxel in humanized transgenic mice.
Volume: 19
Issue: 4
Pages: 821-32
Strain
Attribute String: endonuclease-mediated mutation, mutant strain, targeted mutation, congenic
Strain
Attribute String: congenic, endonuclease-mediated mutation, mutant strain, targeted mutation
Strain
Attribute String: endonuclease-mediated mutation, mutant strain, targeted mutation, congenic
Strain
Attribute String: congenic, targeted mutation, mutant strain, endonuclease-mediated mutation
Strain
Attribute String: endonuclease-mediated mutation, mutant strain, targeted mutation
Strain
Attribute String: endonuclease-mediated mutation, mutant strain, targeted mutation
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: congenic, endonuclease-mediated mutation, mutant strain, targeted mutation
Strain
Attribute String: mutant strain, targeted mutation, endonuclease-mediated mutation
Strain
Attribute String: targeted mutation, mutant strain, endonuclease-mediated mutation
Strain
Attribute String: targeted mutation, mutant strain, endonuclease-mediated mutation, congenic
Strain
Attribute String: congenic, endonuclease-mediated mutation, mutant strain, targeted mutation
Strain
Attribute String: congenic, endonuclease-mediated mutation, mutant strain, targeted mutation
Strain
Attribute String: endonuclease-mediated mutation, mutant strain, targeted mutation
Strain
Attribute String: congenic, endonuclease-mediated mutation, mutant strain, targeted mutation
Strain
Attribute String: targeted mutation, mutant strain, endonuclease-mediated mutation, congenic
Strain
Attribute String: mutant strain, congenic, targeted mutation, endonuclease-mediated mutation
Strain
Attribute String: congenic, endonuclease-mediated mutation, mutant strain, targeted mutation
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: endonuclease-mediated mutation, mutant strain
Allele
Name: transgene insertion 1, Joachim Herz
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication  
First Author: Lacombe J
Year: 2018
Journal: JCI Insight
Title: VKOR paralog VKORC1L1 supports vitamin K-dependent protein carboxylation in vivo.
Volume: 3
Issue: 1
Allele
Name: transchromosomal, human 19, line VL,William Gottschalk
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transchromosomal, human 19, line VL,William Gottschalk
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
Genotype
Symbol: Apoe/Apoe Cst3/Cst3
Background: involves: 129S/SvEv * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Ldlr/Ldlr<+>
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Tg(Eno2-APOE_i4)1Rabr/?
Background: involves: 129P2/OlaHsd * C57BL/6J * ICR
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Tg(Eno2-APOE_i4)1Rabr/?
Background: involves: 129P2/OlaHsd * ICR
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Clu/Clu Tg(APPV717F)109Ili/Tg(APPV717F)109Ili
Background: involves: 129P2/OlaHsd * 129S2/SvPas
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Tg(APPV717F)109Ili/Tg(APPV717F)109Ili
Background: involves: 129P2/OlaHsd
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Tg(GFAP-APOE_i3)37Hol/?
Background: B6.Cg-Tg(GFAP-APOE_i3)37Hol Apoe/J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Cdh18/?
Background: B6.Cg-Apoe Cdh18/J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Tg(GFAP-APOE_i4)22Hol/?
Background: B6.Cg-Apoe Tg(GFAP-APOE_i4)22Hol
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Tg(GFAP-APOE_i3)37Hol/?
Background: B6.Cg-Apoe Tg(GFAP-APOE_i3)37Hol
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Tg(GFAP-APOE_i4)#Hol/?
Background: B6.Cg-Apoe Tg(GFAP-APOE_i4)#Hol
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Tg(APPV717F)109Ili/?
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Fas/Fas
Background: MRL.Cg-Apoe Fas
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Fas/Fas
Background: B6.Cg-Apoe Fas
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Tg(Prnp-Abca1)EHol/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Fabp4/Fabp4 Fabp5/Fabp5
Background: B6.Cg-Fabp4 Fabp5 Apoe
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Tg(Cyp21a1-Apoe)619Fet/?
Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Ldlr/Ldlr<+>
Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Ldlr/Ldlr<+>
Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Clcn5/Clcn5<+> Clcn7/Clcn7 Tg(APOE-cre)VITew/?
Background: involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Gja5/Gja5 Tg(TIE2-lacZ)182Sato/?
Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Ccr2/Ccr2 Cx3cl1/Cx3cl1
Background: B6.Cg-Apoe Cx3cl1 Ccr2
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Abca1/Abca1 Abcg1/Abcg1 Apoe/Apoe
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA * DBA/1LacJ
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Cbs/Cbs Tg(Mt1-CBS)25Waku/?
Background: involves: 129P2/OlaHsd * C3H * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Smarcd1/Smarcd1 Speer6-ps1/Speer6-ps1<+>
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Tg(APPSWE)2576Kha/?
Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * SJL
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(APOE-cre)VITew/?
Background: involves: 129S4/SvJaeSor
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Apoe/Apoe Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Lgals3/Lgals3<+> Tg(Myh11-dre/ERT2)#Cya/?
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Satoh K
Year: 2015
Journal: J Biol Chem
Title: ATP-binding cassette transporter A7 (ABCA7) loss of function alters Alzheimer amyloid processing.
Volume: 290
Issue: 40
Pages: 24152-65
Publication
First Author: Sakaguchi N
Year: 2003
Journal: Neurosci Res
Title: Receptor-type protein tyrosine phosphatase zeta as a component of the signaling receptor complex for midkine-dependent survival of embryonic neurons.
Volume: 45
Issue: 2
Pages: 219-24
Publication
First Author: Han Z
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Two Hsp70 family members expressed in atherosclerotic lesions.
Volume: 100
Issue: 3
Pages: 1256-61
Publication
First Author: Gotthardt M
Year: 2000
Journal: J Biol Chem
Title: Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.
Volume: 275
Issue: 33
Pages: 25616-24
Publication
First Author: Gruen ML
Year: 2005
Journal: J Lipid Res
Title: Persistence of high density lipoprotein particles in obese mice lacking apolipoprotein A-I.
Volume: 46
Issue: 9
Pages: 2007-14
Publication
First Author: Narvekar P
Year: 2009
Journal: Diabetes
Title: Liver-specific loss of lipolysis-stimulated lipoprotein receptor triggers systemic hyperlipidemia in mice.
Volume: 58
Issue: 5
Pages: 1040-9
Publication
First Author: Shen L
Year: 2008
Journal: Diabetes
Title: Brain apolipoprotein E: an important regulator of food intake in rats.
Volume: 57
Issue: 8
Pages: 2092-8
Publication
First Author: Hiuge-Shimizu A
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: Dynamic changes of adiponectin and S100A8 levels by the selective peroxisome proliferator-activated receptor-gamma agonist rivoglitazone.
Volume: 31
Issue: 4
Pages: 792-9
Publication
First Author: Trotter JH
Year: 2011
Journal: J Neurosci
Title: ApoER2 function in the establishment and maintenance of retinal synaptic connectivity.
Volume: 31
Issue: 40
Pages: 14413-23
Publication
First Author: Li H
Year: 1993
Journal: Arterioscler Thromb
Title: Lack of apoA-I is not associated with increased susceptibility to atherosclerosis in mice.
Volume: 13
Issue: 12
Pages: 1814-21
Publication
First Author: Fotakis P
Year: 2015
Journal: Biochemistry
Title: The Effect of Natural LCAT Mutations on the Biogenesis of HDL.
Volume: 54
Issue: 21
Pages: 3348-59
Publication
First Author: Petropoulou PI
Year: 2015
Journal: Biochim Biophys Acta
Title: Lack of LCAT reduces the LPS-neutralizing capacity of HDL and enhances LPS-induced inflammation in mice.
Volume: 1852
Issue: 10 Pt A
Pages: 2106-15
Publication
First Author: Qiu S
Year: 1998
Journal: J Lipid Res
Title: Metabolism of lipoproteins containing apolipoprotein B in hepatic lipase-deficient mice.
Volume: 39
Issue: 8
Pages: 1661-8
Publication
First Author: Elder GA
Year: 2007
Journal: J Neurochem
Title: Elevated plasma cholesterol does not affect brain Abeta in mice lacking the low-density lipoprotein receptor.
Volume: 102
Issue: 4
Pages: 1220-31
Publication
First Author: Li L
Year: 2008
Journal: J Lipid Res
Title: Infection induces a positive acute phase apolipoprotein E response from a negative acute phase gene: role of hepatic LDL receptors.
Volume: 49
Issue: 8
Pages: 1782-93
Publication
First Author: Zhou L
Year: 2012
Journal: PLoS One
Title: Cholecystokinin elevates mouse plasma lipids.
Volume: 7
Issue: 12
Pages: e51011
Publication
First Author: Mulder M
Year: 2004
Journal: Neurobiol Dis
Title: Low-density lipoprotein receptor-knockout mice display impaired spatial memory associated with a decreased synaptic density in the hippocampus.
Volume: 16
Issue: 1
Pages: 212-9
Publication
First Author: Yvan-Charvet L
Year: 2007
Journal: J Clin Invest
Title: Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice.
Volume: 117
Issue: 12
Pages: 3900-8
Publication
First Author: Yan D
Year: 2007
Journal: Arterioscler Thromb Vasc Biol
Title: Expression of human OSBP-related protein 1L in macrophages enhances atherosclerotic lesion development in LDL receptor-deficient mice.
Volume: 27
Issue: 7
Pages: 1618-24
Publication
First Author: Martins IJ
Year: 2000
Journal: J Lipid Res
Title: Relative roles of LDLr and LRP in the metabolism of chylomicron remnants in genetically manipulated mice.
Volume: 41
Issue: 2
Pages: 205-13
Publication
First Author: Cao D
Year: 2006
Journal: Neurobiol Aging
Title: Lack of LDL receptor aggravates learning deficits and amyloid deposits in Alzheimer transgenic mice.
Volume: 27
Issue: 11
Pages: 1632-43
Publication
First Author: Johnson LA
Year: 2008
Journal: Arterioscler Thromb Vasc Biol
Title: Absence of hyperlipidemia in LDL receptor-deficient mice having apolipoprotein B100 without the putative receptor-binding sequences.
Volume: 28
Issue: 10
Pages: 1745-52
Publication
First Author: Constantinou C
Year: 2014
Journal: J Lipid Res
Title: The low density lipoprotein receptor modulates the effects of hypogonadism on diet-induced obesity and related metabolic perturbations.
Volume: 55
Issue: 7
Pages: 1434-47
Publication
First Author: Abisambra JF
Year: 2010
Journal: PLoS One
Title: LDLR expression and localization are altered in mouse and human cell culture models of Alzheimer's disease.
Volume: 5
Issue: 1
Pages: e8556
Publication
First Author: Vrins CL
Year: 2013
Journal: PLoS One
Title: Znf202 affects high density lipoprotein cholesterol levels and promotes hepatosteatosis in hyperlipidemic mice.
Volume: 8
Issue: 2
Pages: e57492
Publication
First Author: Zhu L
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Loss of Macrophage Low-Density Lipoprotein Receptor-Related Protein 1 Confers Resistance to the Antiatherogenic Effects of Tumor Necrosis Factor-α Inhibition.
Volume: 36
Issue: 8
Pages: 1483-95
Publication
First Author: Li H
Year: 2005
Journal: J Neuropathol Exp Neurol
Title: Molecular, anatomical, and biochemical events associated with neurodegeneration in mice with Niemann-Pick type C disease.
Volume: 64
Issue: 4
Pages: 323-33
Publication
First Author: Korporaal SJ
Year: 2007
Journal: Arterioscler Thromb Vasc Biol
Title: Platelet activation by oxidized low density lipoprotein is mediated by CD36 and scavenger receptor-A.
Volume: 27
Issue: 11
Pages: 2476-83
Publication
First Author: Wasser CR
Year: 2014
Journal: Sci Signal
Title: Differential splicing and glycosylation of Apoer2 alters synaptic plasticity and fear learning.
Volume: 7
Issue: 353
Pages: ra113
Publication  
First Author: Ma Z
Year: 2016
Journal: Sci Rep
Title: Orexin signaling regulates both the hippocampal clock and the circadian oscillation of Alzheimer's disease-risk genes.
Volume: 6
Pages: 36035
Publication  
First Author: Buda A
Year: 2023
Journal: Biomolecules
Title: ABCD1 Transporter Deficiency Results in Altered Cholesterol Homeostasis.
Volume: 13
Issue: 9
Publication
First Author: Braun A
Year: 2002
Journal: Circ Res
Title: Loss of SR-BI expression leads to the early onset of occlusive atherosclerotic coronary artery disease, spontaneous myocardial infarctions, severe cardiac dysfunction, and premature death in apolipoprotein E-deficient mice.
Volume: 90
Issue: 3
Pages: 270-6
Publication
First Author: Abildayeva K
Year: 2008
Journal: J Lipid Res
Title: Human apolipoprotein C-I expression in mice impairs learning and memory functions.
Volume: 49
Issue: 4
Pages: 856-69
Publication
First Author: Arai T
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Decreased selective uptake of high density lipoprotein cholesteryl esters in apolipoprotein E knock-out mice.
Volume: 96
Issue: 21
Pages: 12050-5
Publication
First Author: Fanaee-Danesh E
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Astaxanthin exerts protective effects similar to bexarotene in Alzheimer's disease by modulating amyloid-beta and cholesterol homeostasis in blood-brain barrier endothelial cells.
Volume: 1865
Issue: 9
Pages: 2224-2245
Publication  
First Author: Martínez-Iglesias O
Year: 2022
Journal: Int J Mol Sci
Title: Epigenetic Studies in the Male APP/BIN1/COPS5 Triple-Transgenic Mouse Model of Alzheimer's Disease.
Volume: 23
Issue: 5
Publication
First Author: Muñoz-Cabrera JM
Year: 2019
Journal: PLoS One
Title: Bexarotene therapy ameliorates behavioral deficits and induces functional and molecular changes in very-old Triple Transgenic Mice model of Alzheimer´s disease.
Volume: 14
Issue: 10
Pages: e0223578
Publication
First Author: Ochi S
Year: 2020
Journal: Mol Neurobiol
Title: Identifying Blood Transcriptome Biomarkers of Alzheimer's Disease Using Transgenic Mice.
Volume: 57
Issue: 12
Pages: 4941-4951
Publication
First Author: Stukas S
Year: 2012
Journal: Biochim Biophys Acta
Title: The LXR agonist GW3965 increases apoA-I protein levels in the central nervous system independent of ABCA1.
Volume: 1821
Issue: 3
Pages: 536-46
Publication
First Author: Burns MP
Year: 2006
Journal: J Neurochem
Title: The effects of ABCA1 on cholesterol efflux and Abeta levels in vitro and in vivo.
Volume: 98
Issue: 3
Pages: 792-800
Publication
First Author: Schneider JG
Year: 2010
Journal: J Biol Chem
Title: Macrophage fatty-acid synthase deficiency decreases diet-induced atherosclerosis.
Volume: 285
Issue: 30
Pages: 23398-409