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Search results 4401 to 4500 out of 5081 for Mtor

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Type Details Score
Publication
First Author: Xue X
Year: 2018
Journal: J Biol Chem
Title: Protein kinase C? drives fibroblast activation and kidney fibrosis by stimulating autophagic flux.
Volume: 293
Issue: 28
Pages: 11119-11130
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Publication
First Author: Ng SY
Year: 2018
Journal: Blood
Title: RhoA G17V is sufficient to induce autoimmunity and promotes T-cell lymphomagenesis in mice.
Volume: 132
Issue: 9
Pages: 935-947
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Publication
First Author: Krishnamoorthy GP
Year: 2019
Journal: Cancer Discov
Title: EIF1AX and RAS Mutations Cooperate to Drive Thyroid Tumorigenesis through ATF4 and c-MYC.
Volume: 9
Issue: 2
Pages: 264-281
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Publication
First Author: Zeng H
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: mTORC1 signaling suppresses Wnt/?-catenin signaling through DVL-dependent regulation of Wnt receptor FZD level.
Volume: 115
Issue: 44
Pages: E10362-E10369
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Publication
First Author: Duszka K
Year: 2018
Journal: Sci Rep
Title: Complementary intestinal mucosa and microbiota responses to caloric restriction.
Volume: 8
Issue: 1
Pages: 11338
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Publication
First Author: Saito N
Year: 2019
Journal: J Immunol
Title: Involvement of Lamin B1 Reduction in Accelerated Cellular Senescence during Chronic Obstructive Pulmonary Disease Pathogenesis.
Volume: 202
Issue: 5
Pages: 1428-1440
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Publication  
First Author: Chaplot K
Year: 2019
Journal: Dis Model Mech
Title: SOD1 activity threshold and TOR signalling modulate VAP(P58S) aggregation via reactive oxygen species-induced proteasomal degradation in a Drosophila model of amyotrophic lateral sclerosis.
Volume: 12
Issue: 2
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Publication
First Author: Brooks DL
Year: 2019
Journal: Endocrinology
Title: Aldosterone Modulates the Mechanistic Target of Rapamycin Signaling in Male Mice.
Volume: 160
Issue: 4
Pages: 716-728
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Publication
First Author: Stout MB
Year: 2017
Journal: J Gerontol A Biol Sci Med Sci
Title: 17?-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization.
Volume: 72
Issue: 1
Pages: 3-15
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Publication
First Author: Kikani CK
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Activation of PASK by mTORC1 is required for the onset of the terminal differentiation program.
Volume: 116
Issue: 21
Pages: 10382-10391
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Publication
First Author: Zhang HM
Year: 2017
Journal: Sci Rep
Title: Moderate lifelong overexpression of tuberous sclerosis complex 1 (TSC1) improves health and survival in mice.
Volume: 7
Issue: 1
Pages: 834
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Publication
First Author: Kitakaze T
Year: 2020
Journal: Biochim Biophys Acta Mol Cell Res
Title: Extracellular transglutaminase 2 induces myotube hypertrophy through G protein-coupled receptor 56.
Volume: 1867
Issue: 2
Pages: 118563
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Publication
First Author: Zhou J
Year: 2019
Journal: Hum Mol Genet
Title: Titin truncations lead to impaired cardiomyocyte autophagy and mitochondrial function in vivo.
Volume: 28
Issue: 12
Pages: 1971-1981
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Publication
First Author: Reid JJ
Year: 2020
Journal: J Gerontol A Biol Sci Med Sci
Title: Brain Protein Synthesis Rates in the UM-HET3 Mouse Following Treatment With Rapamycin or Rapamycin With Metformin.
Volume: 75
Issue: 1
Pages: 40-49
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Publication
First Author: Wang XS
Year: 2020
Journal: Glia
Title: Activation of G protein-coupled receptor 30 protects neurons by regulating autophagy in astrocytes.
Volume: 68
Issue: 1
Pages: 27-43
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Publication
First Author: Granados-Aparici S
Year: 2019
Journal: Sci Rep
Title: SMAD3 directly regulates cell cycle genes to maintain arrest in granulosa cells of mouse primordial follicles.
Volume: 9
Issue: 1
Pages: 6513
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Publication
First Author: Raman A
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Periostin overexpression in collecting ducts accelerates renal cyst growth and fibrosis in polycystic kidney disease.
Volume: 315
Issue: 6
Pages: F1695-F1707
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Publication
First Author: Son K
Year: 2019
Journal: J Clin Invest
Title: Nontranslational function of leucyl-tRNA synthetase regulates myogenic differentiation and skeletal muscle regeneration.
Volume: 129
Issue: 5
Pages: 2088-2093
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Publication
First Author: Ravi V
Year: 2019
Journal: Nucleic Acids Res
Title: SIRT6 transcriptionally regulates global protein synthesis through transcription factor Sp1 independent of its deacetylase activity.
Volume: 47
Issue: 17
Pages: 9115-9131
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Publication
First Author: Shum M
Year: 2019
Journal: J Biol Chem
Title: Inhibition of mitochondrial complex 1 by the S6K1 inhibitor PF-4708671 partly contributes to its glucose metabolic effects in muscle and liver cells.
Volume: 294
Issue: 32
Pages: 12250-12260
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Publication
First Author: Murugina NE
Year: 2020
Journal: J Biol Chem
Title: Glycolytic reprogramming of macrophages activated by NOD1 and TLR4 agonists: No association with proinflammatory cytokine production in normoxia.
Volume: 295
Issue: 10
Pages: 3099-3114
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Publication
First Author: Endo M
Year: 2020
Journal: J Biol Chem
Title: The two splice variant forms of Cdc42 exert distinct and essential functions in neurogenesis.
Volume: 295
Issue: 14
Pages: 4498-4512
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Publication  
First Author: Zhang L
Year: 2020
Journal: Sci Transl Med
Title: Filamin A inhibition reduces seizure activity in a mouse model of focal cortical malformations.
Volume: 12
Issue: 531
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Publication
First Author: Li H
Year: 2019
Journal: Stem Cells
Title: Melatonin Enhances Proliferation and Modulates Differentiation of Neural Stem Cells Via Autophagy in Hyperglycemia.
Volume: 37
Issue: 4
Pages: 504-515
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Publication
First Author: Wang X
Year: 2019
Journal: Haematologica
Title: Rheb1 loss leads to increased hematopoietic stem cell proliferation and myeloid-biased differentiation in vivo.
Volume: 104
Issue: 2
Pages: 245-255
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Publication
First Author: Zhao X
Year: 2019
Journal: Aging Cell
Title: SLC1A5 glutamine transporter is a target of MYC and mediates reduced mTORC1 signaling and increased fatty acid oxidation in long-lived Myc hypomorphic mice.
Volume: 18
Issue: 3
Pages: e12947
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Publication
First Author: Baek MO
Year: 2019
Journal: Sci Rep
Title: Simulated microgravity inhibits C2C12 myogenesis via phospholipase D2-induced Akt/FOXO1 regulation.
Volume: 9
Issue: 1
Pages: 14910
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Publication
First Author: Villegas-Mendez A
Year: 2020
Journal: J Immunol
Title: Exhausted CD4(+) T Cells during Malaria Exhibit Reduced mTORc1 Activity Correlated with Loss of T-bet Expression.
Volume: 205
Issue: 6
Pages: 1608-1619
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Publication
First Author: Diwakar L
Year: 2021
Journal: Sci Rep
Title: Endothelin-1 mediated vasoconstriction leads to memory impairment and synaptic dysfunction.
Volume: 11
Issue: 1
Pages: 4868
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Publication
First Author: Li G
Year: 2013
Journal: Cancer Prev Res (Phila)
Title: Dietary resveratrol prevents development of high-grade prostatic intraepithelial neoplastic lesions: involvement of SIRT1/S6K axis.
Volume: 6
Issue: 1
Pages: 27-39
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Publication
First Author: Breda CNS
Year: 2021
Journal: J Immunol
Title: Loss of mTORC2 Activity in Neutrophils Impairs Fusion of Granules and Affects Cellular Metabolism Favoring Increased Bacterial Burden in Sepsis.
Volume: 207
Issue: 2
Pages: 626-639
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Publication  
First Author: Valvezan AJ
Year: 2020
Journal: JCI Insight
Title: IMPDH inhibitors for antitumor therapy in tuberous sclerosis complex.
Volume: 5
Issue: 7
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Publication
First Author: Jan CI
Year: 2016
Journal: Int J Biol Sci
Title: Fenofibrate Suppresses Oral Tumorigenesis via Reprogramming Metabolic Processes: Potential Drug Repurposing for Oral Cancer.
Volume: 12
Issue: 7
Pages: 786-98
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Publication
First Author: Tan SH
Year: 2014
Journal: Autophagy
Title: Critical role of SCD1 in autophagy regulation via lipogenesis and lipid rafts-coupled AKT-FOXO1 signaling pathway.
Volume: 10
Issue: 2
Pages: 226-42
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Publication
First Author: Barutcu SA
Year: 2018
Journal: Autophagy
Title: Role of the MAPK/cJun NH(2)-terminal kinase signaling pathway in starvation-induced autophagy.
Volume: 14
Issue: 9
Pages: 1586-1595
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Publication  
First Author: Bechelli J
Year: 2021
Journal: Front Immunol
Title: Subversion of Host Innate Immunity by Rickettsia australis via a Modified Autophagic Response in Macrophages.
Volume: 12
Pages: 638469
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Publication  
First Author: Kazyken D
Year: 2019
Journal: Sci Signal
Title: AMPK directly activates mTORC2 to promote cell survival during acute energetic stress.
Volume: 12
Issue: 585
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Publication
First Author: Miao J
Year: 2018
Journal: J Endocrinol
Title: Resistin inhibits neuronal autophagy through Toll-like receptor 4.
Volume: 238
Issue: 1
Pages: 77-89
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Publication
First Author: Pellegrino R
Year: 2014
Journal: Hepatology
Title: EEF1A2 inactivates p53 by way of PI3K/AKT/mTOR-dependent stabilization of MDM4 in hepatocellular carcinoma.
Volume: 59
Issue: 5
Pages: 1886-99
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Publication  
First Author: Li W
Year: 2021
Journal: JCI Insight
Title: Lupus susceptibility gene Esrrg modulates regulatory T cells through mitochondrial metabolism.
Volume: 6
Issue: 14
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Publication  
First Author: Aquila S
Year: 2020
Journal: Cells
Title: The Tumor Suppressor PTEN as Molecular Switch Node Regulating Cell Metabolism and Autophagy: Implications in Immune System and Tumor Microenvironment.
Volume: 9
Issue: 7
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Publication
First Author: Kawabata S
Year: 2015
Journal: Oncotarget
Title: Epidermal growth factor receptor as a novel molecular target for aggressive papillary tumors in the middle ear and temporal bone.
Volume: 6
Issue: 13
Pages: 11357-68
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Publication
First Author: Kuiper-Makris C
Year: 2020
Journal: Sci Rep
Title: Mendelian randomization and experimental IUGR reveal the adverse effect of low birth weight on lung structure and function.
Volume: 10
Issue: 1
Pages: 22395
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Publication  
First Author: Pascual F
Year: 2018
Journal: J Am Heart Assoc
Title: Modeling the Transition From Decompensated to Pathological Hypertrophy.
Volume: 7
Issue: 8
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Publication
First Author: Ma Y
Year: 2017
Journal: Mol Neurobiol
Title: Progranulin Protects Hippocampal Neurogenesis via Suppression of Neuroinflammatory Responses Under Acute Immune Stress.
Volume: 54
Issue: 5
Pages: 3717-3728
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Publication
First Author: Cao Y
Year: 2018
Journal: Neoplasia
Title: Cooperation Between Pten and Smad4 in Murine Salivary Gland Tumor Formation and Progression.
Volume: 20
Issue: 8
Pages: 764-774
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Publication
First Author: Kim TH
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Copine1 regulates neural stem cell functions during brain development.
Volume: 495
Issue: 1
Pages: 168-173
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Publication
First Author: Zhou Z
Year: 2022
Journal: Cell Death Dis
Title: ADRB3 induces mobilization and inhibits differentiation of both breast cancer cells and myeloid-derived suppressor cells.
Volume: 13
Issue: 2
Pages: 141
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Publication  
First Author: Zhong L
Year: 2022
Journal: JCI Insight
Title: Transient expansion and myofibroblast conversion of adipogenic lineage precursors mediate bone marrow repair after radiation.
Volume: 7
Issue: 7
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Publication
First Author: Dulmovits BM
Year: 2022
Journal: Blood
Title: HMGB1-mediated restriction of EPO signaling contributes to anemia of inflammation.
Volume: 139
Issue: 21
Pages: 3181-3193
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Publication
First Author: Blandino-Rosano M
Year: 2022
Journal: Am J Physiol Endocrinol Metab
Title: Novel roles of mTORC2 in regulation of insulin secretion by actin filament remodeling.
Volume: 323
Issue: 2
Pages: E133-E144
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Publication
First Author: Willows JW
Year: 2023
Journal: Aging Cell
Title: Age-related changes to adipose tissue and peripheral neuropathy in genetically diverse HET3 mice differ by sex and are not mitigated by rapamycin longevity treatment.
Volume: 22
Issue: 4
Pages: e13784
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Publication  
First Author: Fang Y
Year: 2023
Journal: Front Immunol
Title: Fibronectin leucine-rich transmembrane protein 2 drives monocyte differentiation into macrophages via the UNC5B-Akt/mTOR axis.
Volume: 14
Pages: 1162004
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Publication  
First Author: Lee SE
Year: 2023
Journal: Cells Dev
Title: Cell starvation regulates ceramide-induced autophagy in mouse preimplantation embryo development.
Volume: 175
Pages: 203859
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Publication  
First Author: Bakker D
Year: 2023
Journal: Cells
Title: Immunity against Non-Melanoma Skin Cancer and the Effect of Immunosuppressive Medication on Non-Melanoma Skin Cancer Risk in Solid Organ Transplant Recipients.
Volume: 12
Issue: 20
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Publication  
First Author: Pan Y
Year: 2023
Journal: Front Aging Neurosci
Title: Rhes depletion promotes striatal accumulation and aggregation of mutant huntingtin in a presymptomatic HD mouse model.
Volume: 15
Pages: 1237018
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Publication  
First Author: Hou H
Year: 2023
Journal: Mol Med Rep
Title: Tripartite motif?containing 14 may aggravate cardiac hypertrophy via the AKT signalling pathway in neonatal rat cardiomyocytes and transgenic mice.
Volume: 28
Issue: 3
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Publication
First Author: Lin Y
Year: 2023
Journal: Acta Pharm Sin B
Title: Reactivation of PPAR? alleviates myocardial lipid accumulation and cardiac dysfunction by improving fatty acid ?-oxidation in Dsg2-deficient arrhythmogenic cardiomyopathy.
Volume: 13
Issue: 1
Pages: 192-203
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Publication  
First Author: Liu Y
Year: 2024
Journal: Cancer Lett
Title: CPT1A loss disrupts BCAA metabolism to confer therapeutic vulnerability in TP53-mutated liver cancer.
Volume: 595
Pages: 217006
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Publication
First Author: Thomas ME 3rd
Year: 2024
Journal: Leukemia
Title: Functional characterization of cooperating MGA mutations in RUNX1::RUNX1T1 acute myeloid leukemia.
Volume: 38
Issue: 5
Pages: 991-1002
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Publication
First Author: Mul? P
Year: 2024
Journal: Gastroenterology
Title: WNT Oncogenic Transcription Requires MYC Suppression of Lysosomal Activity and EPCAM Stabilization in Gastric Tumors.
Volume: 167
Issue: 5
Pages: 903-918
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Publication
First Author: Haque TT
Year: 2024
Journal: Sci Immunol
Title: TGF? prevents IgE-mediated allergic disease by restraining T follicular helper 2 differentiation.
Volume: 9
Issue: 91
Pages: eadg8691
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Publication
First Author: Tsang DKL
Year: 2022
Journal: Gut Microbes
Title: A single cell survey of the microbial impacts on the mouse small intestinal epithelium.
Volume: 14
Issue: 1
Pages: 2108281
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Publication
First Author: Mohammadhosseini M
Year: 2025
Journal: Sci Transl Med
Title: Targeting the CD74 signaling axis suppresses inflammation and rescues defective hematopoiesis in RUNX1-familial platelet disorder.
Volume: 17
Issue: 780
Pages: eadn9832
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Publication
First Author: Li D
Year: 2022
Journal: Sci Immunol
Title: SLAMF3 and SLAMF4 are immune checkpoints that constrain macrophage phagocytosis of hematopoietic tumors.
Volume: 7
Issue: 67
Pages: eabj5501
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Publication
First Author: Arsham AM
Year: 2002
Journal: J Biol Chem
Title: Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription.
Volume: 277
Issue: 17
Pages: 15162-70
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Publication
First Author: Giegerich AK
Year: 2014
Journal: Autophagy
Title: Autophagy-dependent PELI3 degradation inhibits proinflammatory IL1B expression.
Volume: 10
Issue: 11
Pages: 1937-52
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Publication  
First Author: Thapa D
Year: 2026
Journal: Cancers (Basel)
Title: MDM4 at the Crossroads: Beyond p53 and MDM2.
Volume: 18
Issue: 7
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Publication
First Author: Castillo SD
Year: 2025
Journal: Cancer Discov
Title: Somatic Uniparental Disomy of PTEN in Endothelial Cells Causes Vascular Malformations in Patients with PTEN Hamartoma Tumor Syndrome.
Volume: 15
Issue: 7
Pages: 1350-1362
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Publication
First Author: Javary J
Year: 2018
Journal: Gut
Title: Liver Reptin/RUVBL2 controls glucose and lipid metabolism with opposite actions on mTORC1 and mTORC2 signalling.
Volume: 67
Issue: 12
Pages: 2192-2203
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Publication
First Author: Marderosian M
Year: 2006
Journal: Oncogene
Title: Tristetraprolin regulates Cyclin D1 and c-Myc mRNA stability in response to rapamycin in an Akt-dependent manner via p38 MAPK signaling.
Volume: 25
Issue: 47
Pages: 6277-90
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Publication
First Author: Housden BE
Year: 2015
Journal: Sci Signal
Title: Identification of potential drug targets for tuberous sclerosis complex by synthetic screens combining CRISPR-based knockouts with RNAi.
Volume: 8
Issue: 393
Pages: rs9
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Publication
First Author: Liu Z
Year: 2014
Journal: J Biol Chem
Title: PDK4 protein promotes tumorigenesis through activation of cAMP-response element-binding protein (CREB)-Ras homolog enriched in brain (RHEB)-mTORC1 signaling cascade.
Volume: 289
Issue: 43
Pages: 29739-49
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Publication
First Author: Zhang X
Year: 2026
Journal: Glia
Title: Suppression of Astrocytic PirB Alleviates A??-Induced Excitotoxicity and Cognitive Deficits via EAAT Expression.
Volume: 74
Issue: 2
Pages: e70130
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Publication      
First Author: Wang B
Year: 2023
Journal: bioRxiv
Title: TFEB-vacuolar ATPase signaling regulates lysosomal function and microglial activation in tauopathy.
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Publication
First Author: Chang S
Year: 2026
Journal: Exp Mol Med
Title: Targeting the SIRT6-TDO2/KYNA-mTOR axis rescues synaptic and cognitive deficits in fetal growth restriction offspring.
Volume: 58
Issue: 6
Pages: 1987-2006
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Publication  
First Author: Yang H
Year: 2026
Journal: J Clin Invest
Title: SLC15A3-mediated dipeptide metabolism confers antimetabolite resistance in lymphoma via mTORC1 activation.
Volume: 136
Issue: 14
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Publication
First Author: Yamada O
Year: 2012
Journal: Mol Cancer Ther
Title: JAK-STAT and JAK-PI3K-mTORC1 pathways regulate telomerase transcriptionally and posttranslationally in ATL cells.
Volume: 11
Issue: 5
Pages: 1112-21
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Publication
First Author: Ziegler ME
Year: 2016
Journal: Angiogenesis
Title: mTORC2 mediates CXCL12-induced angiogenesis.
Volume: 19
Issue: 3
Pages: 359-71
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Publication
First Author: Hu X
Year: 2020
Journal: Lab Invest
Title: PI3K-Akt-mTOR/PFKFB3 pathway mediated lung fibroblast aerobic glycolysis and collagen synthesis in lipopolysaccharide-induced pulmonary fibrosis.
Volume: 100
Issue: 6
Pages: 801-811
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Publication
First Author: Cho SH
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Hypoxia-inducible factors in CD4(+) T cells promote metabolism, switch cytokine secretion, and T cell help in humoral immunity.
Volume: 116
Issue: 18
Pages: 8975-8984
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Publication
First Author: Chimin P
Year: 2017
Journal: J Lipid Res
Title: Adipocyte mTORC1 deficiency promotes adipose tissue inflammation and NLRP3 inflammasome activation via oxidative stress and de novo ceramide synthesis.
Volume: 58
Issue: 9
Pages: 1797-1807
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Publication    
First Author: Yang C
Year: 2018
Journal: Elife
Title: mTORC1 and mTORC2 differentially promote natural killer cell development.
Volume: 7
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Protein
Organism: Mus musculus/domesticus
Length: 1165  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 1108  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 677  
Fragment?: true
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Protein
Organism: Mus musculus/domesticus
Length: 888  
Fragment?: true
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Protein
Organism: Mus musculus/domesticus
Length: 1138  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 631  
Fragment?: true
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Protein
Organism: Mus musculus/domesticus
Length: 171  
Fragment?: true
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Protein
Organism: Mus musculus/domesticus
Length: 373  
Fragment?: true
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Publication
First Author: Lee AS
Year: 2015
Journal: Nature
Title: eIF3 targets cell-proliferation messenger RNAs for translational activation or repression.
Volume: 522
Issue: 7554
Pages: 111-4
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Publication
First Author: Lee AS
Year: 2016
Journal: Nature
Title: eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.
Volume: 536
Issue: 7614
Pages: 96-9
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Publication
First Author: Lawrence RE
Year: 2019
Journal: Science
Title: Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex.
Volume: 366
Issue: 6468
Pages: 971-977
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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