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Search results 4501 to 4600 out of 4906 for Isl1

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Type Details Score
Genotype
Genotype
Symbol: Rspo3/Rspo3 Isl1/Isl1<+>
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nkx2-5/Nkx2-5 Isl1/Isl1<+>
Background: involves: 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nkx2-5/Nkx2-5 Isl1/Isl1<+>
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Casz1/Casz1 Isl1/Isl1<+>
Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bcor/? Isl1/Isl1<+>
Background: involves: 129S1/Sv
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Jun/Jun Isl1/Isl1<+>
Background: involves: 129P2/OlaHsd * 129S/Sv
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Isl1/Isl1<+> Jun/Jun<+>
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prdm12/Prdm12 Isl1/Isl1<+>
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Isl1/Isl1 Neurog2/Neurog2 Tg(Chx10-EGFP/cre,-ALPP)2Clc/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gsk3b/Gsk3b Isl1/Isl1<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Isl1/Isl1<+> Prox1/Prox1<+>
Background: involves: 129S/Sv * C57BL/6NCrlj * CBA/JNCrlj
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Isl1/Isl1<+> Prox1/Prox1
Background: involves: 129S/Sv * C57BL/6NCrlj * CBA/JNCrlj
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Isl1/Isl1<+> Smad4/Smad4
Background: involves: 129S/Sv * 129S6/SvEvTac
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Aplnr/Aplnr Isl1/Isl1<+>
Background: involves: 129 * C57BL/6N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hdac3/Hdac3 Isl1/Isl1<+>
Background: involves: 129S/Sv * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Isl1/Isl1<+> Neurod1/Neurod1
Background: involves: 129
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Isl1/Isl1 Pou4f1/Pou4f1 Tg(Pax2-cre)1Akg/?
Background: involves: 129S7/SvEvBrd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Brd4/Brd4 Isl1/Isl1<+>
Background: involves: 129
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Brd4/Brd4<+> Isl1/Isl1<+>
Background: involves: 129
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nrg1/Nrg1 Isl1/Isl1<+>
Background: involves: 129P2/OlaHsd * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bmpr1a/Bmpr1a Isl1/Isl1<+>
Background: involves: 129S4/SvJae * 129S7/SvEvBrd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgf8/Fgf8 Isl1/Isl1<+>
Background: involves: 129S/Sv
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Aldh1a2/Aldh1a2 Isl1/Isl1<+>
Background: involves: 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smo/Smo Isl1/Isl1<+>
Background: involves: 129S/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Isl1/Isl1<+> Mapt/Mapt<+>
Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Isl1/Isl1<+> Shc1/Shc1
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Etv1/Etv1 Isl1/Isl1<+>
Background: involves: 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Isl1/Isl1 Pou4f2/Pou4f2 Tg(Six3-cre)69Frty/?
Background: involves: 129S6/SvEvTac * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgf8/Fgf8 Isl1/Isl1<+>
Background: involves: 129S/Sv * Black Swiss * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hand2/Hand2 Isl1/Isl1<+>
Background: involves: 129 * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Maf/Maf Isl1/Isl1<+>
Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Irx3/Irx3 Irx5/Irx5 Isl1/Isl1<+>
Background: involves: 129S/Sv
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Epha4/Epha4 Isl1/Isl1<+> Tg(Hlxb9-GFP)1Tmj/?
Background: involves: 129S/Sv * Black Swiss * C57BL/6J * CD-1 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Isl1/Isl1<+> Pax9/Pax9
Background: involves: 129 * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bcor/Bcor<+> Isl1/Isl1<+>
Background: involves: 129S1/Sv
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dll4/Dll4<+> Isl1/Isl1<+>
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Jun/Jun Isl1/Isl1<+>
Background: involves: 129P2/OlaHsd * 129S/Sv * 129X1/SvJ * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Isl1/Isl1<+> Zfp503/Zfp503 Tg(CAG-cat,-EGFP)1Rbns/?
Background: involves: 129 * 129X1/SvJ * C57BL/6 * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Isl1/Isl1<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCrl * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Isl1/Isl1<+> Ngfr/Ngfr
Background: involves: 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Isl1/Isl1<+>
Background: involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgf8/Fgf8 Isl1/Isl1<+>
Background: involves: 129/Sv * Black Swiss * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Isl1/Isl1<+>
Background: involves: 129S/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Isl1/Isl1<+>
Background: involves: 129S4/SvJaeSor * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Isl1/Isl1<+>
Background: involves: 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Isl1/Isl1<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCr
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Isl1/Isl1<+>
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ebf1/Ebf1 Isl1/Isl1<+>
Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Isl1/Isl1<+>
Background: involves: 129 * 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Isl1/Isl1 Tg(Neurod1-cre)1Able/?
Background: mixed
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Isl1/Isl1<+>
Background: involves: 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Isl1/Isl1 Tg(Neurod1-cre)1Able/?
Background: involves: 129 * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Isl1/Isl1
Background: involves: 129 * Black Swiss * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Isl1/Isl1<+>
Background: involves: 129 * Black Swiss * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Isl1/Isl1
Background: involves: 129 * Black Swiss * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Isl1/Isl1<+>
Background: involves: 129 * Black Swiss * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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HT Experiment
GSE15232 | A Regulatory Pathway Involving Notch1/beta-Catenin/Isl1 Determines Cardiac Progenitor Cell Fate
Series Id: E-GEOD-15232
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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Strain
MGI:7703438 | 129S1.Cg-Tg(Isl1-EGFP*)1Slp/J
Attribute String: congenic, mutant strain, transgenic
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Strain
MGI:3783248 | B6.Cg-pizaa Tg(Isl1-EGFP*)1Slp
Attribute String: congenic, chemically induced mutation, transgenic
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Strain
MGI:5307242 | STOCK Tg(Isl1-EGFP*)1Slp/J
Attribute String: mutant stock, transgenic
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Allele
Tg(Isl1-EGFP)2Slp | MGI:3779017
Name: transgene insertion 2, Samuel L Pfaff
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Isl1-lacZ)5Cka | MGI:5578567
Name: transgene insertion 5, Claudia Kappen
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
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Genotype
Genotype
Symbol: piza/piza Tg(Isl1-EGFP*)1Slp/?
Background: B6.Cg-pizaa Tg(Isl1-EGFP*)1Slp
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Vesp/? Tg(Isl1-EGFP*)1Slp/?
Background: B6.Cg-Vesp Tg(Isl1-EGFP*)1Slp
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Isl1-EGFP*)1Slp/?
Background: involves: 129S/SvEv * BALB/c * C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Isl1-EGFP*)1Slp/?
Background: involves: 129S1/Sv * C57BL/6J
Zygosity: ot
Has Mutant Allele: true
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Strain
MGI:3783254 | B6.Cg-colm Tg(Isl1-EGFP*)1Slp
Attribute String: chemically induced mutation, congenic, transgenic
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Strain
MGI:3783252 | B6.Cg-dleon Tg(Isl1-EGFP*)1Slp
Attribute String: chemically induced mutation, congenic, transgenic
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Strain
MGI:5578566 | FVB/N-Tg(Isl1-lacZ)5Cka/Mmjax
Attribute String: transgenic, mutant strain, coisogenic
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Genotype
Genotype
Symbol: colm/colm Tg(Isl1-EGFP*)1Slp/?
Background: B6.Cg-colm Tg(Isl1-EGFP*)1Slp
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: crts/crts Tg(Isl1-EGFP*)1Slp/?
Background: B6.Cg-crts Tg(Isl1-EGFP*)1Slp
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: dleon/dleon Tg(Isl1-EGFP*)1Slp/?
Background: B6.Cg-dleon Tg(Isl1-EGFP*)1Slp
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Isl1/Isl1 Pou4f2/Pou4f2 Tg(Six3-cre)69Frty/?
Background: involves: 129S6/SvEvTac * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Isl1/Isl1 H2az2/H2az2<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dvl3/Dvl3 Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Isl1/Isl1<+>
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * Black Swiss
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hand2/Hand2 Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Isl1/Isl1<+>
Background: involves: 129S4/SvJaeSor * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Isl1/Isl1<+> Msx1/Msx1<+> Pax9/Pax9
Background: involves: 129 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Isl1/Isl1<+> Porcn/?
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Isl1/Isl1<+> Porcn/Porcn<+>
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Isl1/Isl1<+> Tg(Neurod1-cre)1Able/?
Background: mixed
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Isl1/Isl1<+>
Background: involves: 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Isl1/Isl1<+> Tg(Neurod1-cre)1Able/?
Background: involves: 129 * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Publication
27181683 | J:237642
First Author: Park JG
Year: 2016
Journal: Am J Hum Genet
Title: Loss of MAFB Function in Humans and Mice Causes Duane Syndrome, Aberrant Extraocular Muscle Innervation, and Inner-Ear Defects.
Volume: 98
Issue: 6
Pages: 1220-1227
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Publication
36083589 | J:328991
First Author: Vemula SK
Year: 2022
Journal: Invest Ophthalmol Vis Sci
Title: Impaired Extraocular Muscle Innervation Is Present Before Eye Opening in a Mouse Model of Infantile Nystagmus Syndrome.
Volume: 63
Issue: 10
Pages: 4
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Strain
MGI:3783250 | B6.Cg-Mycbp2<mgln> Tg(Isl1-EGFP*)1Slp
Attribute String: chemically induced mutation, congenic, transgenic
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Genotype
Genotype
Symbol: Mycbp2/Mycbp2 Tg(Isl1-EGFP*)1Slp/?
Background: B6.Cg-Mycbp2 Tg(Isl1-EGFP*)1Slp
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mycbp2/Mycbp2 Tg(Isl1-EGFP*)1Slp/?
Background: B6.Cg-Mycbp2 Tg(Isl1-EGFP*)1Slp
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mycbp2/Mycbp2 Tg(Isl1-EGFP)2Slp/?
Background: involves: C3H * C57BL/6 * DBA/2J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kif21a/Kif21a Tg(Isl1-EGFP*)1Slp/?
Background: involves: 129S1/Sv * 129S4/SvJae * BALB/c * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Map1b/Map1b Tg(Isl1-EGFP*)1Slp/?
Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mafb/Mafb Tg(Isl1-EGFP*)1Slp/?
Background: involves: 129S4/SvJae * BALB/c * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mafb/Mafb<+> Tg(Isl1-EGFP*)1Slp/?
Background: involves: 129S4/SvJae * BALB/c * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Plxnd1/Plxnd1 Tg(Isl1-EGFP*)1Slp/?
Background: involves: 129S/SvEv * BALB/c * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Publication
23750000 | -
First Author: Gadd MS
Year: 2013
Journal: J Biol Chem
Title: A structural basis for the regulation of the LIM-homeodomain protein islet 1 (Isl1) by intra- and intermolecular interactions.
Volume: 288
Issue: 30
Pages: 21924-35
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Protein Domain
IPR041363 | LID
Type: Domain
Description: LIM-homeodomain (LIM-HD) proteins are transcription factors that are critical in the development of many cell types and tissues. The activity of LIM-HD proteins is dependent on the essential cofactor LIM domain-binding protein 1 (Ldb1). This entry represents a 30-residue LIM interaction domain (LID) that binds to the LIM domains of all LIM-HD and closely related LIM-only (LMO) proteins. Isl1 (Insulin gene enhancer protein 1) and Isl2 each contain a LID-like sequence in their C-terminal regions, the Lhx3-binding domain (LBD), which binds the LIM domains Lhx3 and Lhx4 [].
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Publication
31157617 | J:277321
   
First Author: An D
Year: 2019
Journal: Elife
Title: Stem cell-derived cranial and spinal motor neurons reveal proteostatic differences between ALS resistant and sensitive motor neurons.
Volume: 8
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Publication
39333082 | J:355214
First Author: Lee AS
Year: 2024
Journal: Nat Commun
Title: A cell type-aware framework for nominating non-coding variants in Mendelian regulatory disorders.
Volume: 15
Issue: 1
Pages: 8268
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Genotype
Genotype
Symbol: Kif21a/Kif21a<+> Map1b/Map1b<+> Tg(Isl1-EGFP*)1Slp/?
Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/c * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Chn1/Chn1 Tg(Isl1-EGFP*)1Slp/?
Background: involves: 129S1/Sv * 129S6/SvEvTac * BALB/c * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Publication
25908435 | J:222799
 
First Author: Pathania R
Year: 2015
Journal: Nat Commun
Title: DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis.
Volume: 6
Pages: 6910
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