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Search results 4901 to 5000 out of 5081 for Mtor

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Type Details Score
Publication
First Author: Arif A
Year: 2017
Journal: Nature
Title: EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice.
Volume: 542
Issue: 7641
Pages: 357-361
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Publication
First Author: Yu X
Year: 2018
Journal: J Exp Med
Title: Metabolic control of regulatory T cell stability and function by TRAF3IP3 at the lysosome.
Volume: 215
Issue: 9
Pages: 2463-2476
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Publication
First Author: Ruiz A
Year: 2018
Journal: Sci Rep
Title: Over-expression of a retinol dehydrogenase (SRP35/DHRS7C) in skeletal muscle activates mTORC2, enhances glucose metabolism and muscle performance.
Volume: 8
Issue: 1
Pages: 636
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Publication
First Author: Meng ZX
Year: 2014
Journal: Diabetes
Title: The Baf60c/Deptor pathway links skeletal muscle inflammation to glucose homeostasis in obesity.
Volume: 63
Issue: 5
Pages: 1533-45
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Publication
First Author: Yan J
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Activation of autophagy rescues synaptic and cognitive deficits in fragile X mice.
Volume: 115
Issue: 41
Pages: E9707-E9716
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Publication
First Author: Gerlach BD
Year: 2021
Journal: Cell Metab
Title: Efferocytosis induces macrophage proliferation to help resolve tissue injury.
Volume: 33
Issue: 12
Pages: 2445-2463.e8
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Publication
First Author: Everts B
Year: 2014
Journal: Nat Immunol
Title: TLR-driven early glycolytic reprogramming via the kinases TBK1-IKK? supports the anabolic demands of dendritic cell activation.
Volume: 15
Issue: 4
Pages: 323-32
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Publication
First Author: Opejin A
Year: 2020
Journal: Cell Rep
Title: A Two-Step Process of Effector Programming Governs CD4(+) T Cell Fate Determination Induced by Antigenic Activation in the Steady State.
Volume: 33
Issue: 8
Pages: 108424
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Publication
First Author: Newton RH
Year: 2018
Journal: Nat Immunol
Title: Maintenance of CD4 T cell fitness through regulation of Foxo1.
Volume: 19
Issue: 8
Pages: 838-848
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Publication
First Author: Do MH
Year: 2023
Journal: Immunity
Title: Reprogramming tumor-associated macrophages to outcompete endovascular endothelial progenitor cells and suppress tumor neoangiogenesis.
Volume: 56
Issue: 11
Pages: 2555-2569.e5
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Publication
First Author: Wang D
Year: 2025
Journal: Nat Commun
Title: mTORC1 signaling in group 2 innate lymphoid cells coordinates neuro-immune crosstalk in allergic lung inflammation.
Volume: 17
Issue: 1
Pages: 62
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Publication
First Author: Magee JA
Year: 2012
Journal: Cell Stem Cell
Title: Temporal changes in PTEN and mTORC2 regulation of hematopoietic stem cell self-renewal and leukemia suppression.
Volume: 11
Issue: 3
Pages: 415-28
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Publication  
First Author: Zhang S
Year: 2023
Journal: J Clin Invest
Title: The UBE2C/CDH1/DEPTOR axis is an oncogene and tumor suppressor cascade in lung cancer cells.
Volume: 133
Issue: 4
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Publication
First Author: Kogot-Levin A
Year: 2020
Journal: Cell Rep
Title: Proximal Tubule mTORC1 Is a Central Player in the Pathophysiology of Diabetic Nephropathy and Its Correction by SGLT2 Inhibitors.
Volume: 32
Issue: 4
Pages: 107954
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Publication
First Author: Riahi Y
Year: 2023
Journal: Diabetologia
Title: Hyperglucagonaemia in diabetes: altered amino acid metabolism triggers mTORC1 activation, which drives glucagon production.
Volume: 66
Issue: 10
Pages: 1925-1942
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Publication
First Author: Zhang X
Year: 2018
Journal: Cell Rep
Title: Adipose mTORC1 Suppresses Prostaglandin Signaling and Beige Adipogenesis via the CRTC2-COX-2 Pathway.
Volume: 24
Issue: 12
Pages: 3180-3193
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Publication
First Author: Haller S
Year: 2017
Journal: Cell Stem Cell
Title: mTORC1 Activation during Repeated Regeneration Impairs Somatic Stem Cell Maintenance.
Volume: 21
Issue: 6
Pages: 806-818.e5
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Publication
First Author: Bohin N
Year: 2020
Journal: Cell Mol Gastroenterol Hepatol
Title: Insulin-like Growth Factor-1 and mTORC1 Signaling Promote the Intestinal Regenerative Response After Irradiation Injury.
Volume: 10
Issue: 4
Pages: 797-810
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Publication
First Author: Meng ZX
Year: 2017
Journal: Mol Cell
Title: Glucose Sensing by Skeletal Myocytes Couples Nutrient Signaling to Systemic Homeostasis.
Volume: 66
Issue: 3
Pages: 332-344.e4
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Publication
First Author: Garc?a-Gil A
Year: 2018
Journal: Virulence
Title: SopB activates the Akt-YAP pathway to promote Salmonella survival within B cells.
Volume: 9
Issue: 1
Pages: 1390-1402
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Publication
First Author: Huang L
Year: 2017
Journal: PLoS Biol
Title: Rictor positively regulates B cell receptor signaling by modulating actin reorganization via ezrin.
Volume: 15
Issue: 8
Pages: e2001750
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Publication
First Author: Gan Z
Year: 2024
Journal: Sci Bull (Beijing)
Title: Excitatory amino acid transporter supports inflammatory macrophage responses.
Volume: 69
Issue: 15
Pages: 2405-2419
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Publication
First Author: Perumalsamy LR
Year: 2012
Journal: Sci Signal
Title: Distinct spatial and molecular features of notch pathway assembly in regulatory T cells.
Volume: 5
Issue: 234
Pages: ra53
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Publication
First Author: Lee JH
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: SREBP-1a-stimulated lipid synthesis is required for macrophage phagocytosis downstream of TLR4-directed mTORC1.
Volume: 115
Issue: 52
Pages: E12228-E12234
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Publication
First Author: Xiong X
Year: 2025
Journal: Cell Death Differ
Title: DEPTOR suppresses lymphomagenesis by promoting EGFR degradation via HUWE1 E3 ligase.
Volume: 32
Issue: 10
Pages: 1820-1832
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Publication
First Author: Hua C
Year: 2014
Journal: Exp Hematol
Title: Rictor/mammalian target of rapamycin 2 regulates the development of Notch1 induced murine T-cell acute lymphoblastic leukemia via forkhead box O3.
Volume: 42
Issue: 12
Pages: 1031-40.e1-4
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Publication
First Author: Bridges CR
Year: 2017
Journal: Sci Rep
Title: USP9X deubiquitylating enzyme maintains RAPTOR protein levels, mTORC1 signalling and proliferation in neural progenitors.
Volume: 7
Issue: 1
Pages: 391
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Publication
First Author: Hu Y
Year: 2018
Journal: J Biol Chem
Title: Fructose and glucose can regulate mammalian target of rapamycin complex 1 and lipogenic gene expression via distinct pathways.
Volume: 293
Issue: 6
Pages: 2006-2014
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Publication
First Author: He A
Year: 2020
Journal: Mol Cell
Title: Acetyl-CoA Derived from Hepatic Peroxisomal ?-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 Activation.
Volume: 79
Issue: 1
Pages: 30-42.e4
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Publication
First Author: Canaud G
Year: 2013
Journal: Nat Med
Title: AKT2 is essential to maintain podocyte viability and function during chronic kidney disease.
Volume: 19
Issue: 10
Pages: 1288-96
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Publication  
First Author: Uehara K
Year: 2024
Journal: J Clin Invest
Title: mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b.
Volume: 134
Issue: 7
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Publication
First Author: Menk AV
Year: 2018
Journal: Cell Rep
Title: Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions.
Volume: 22
Issue: 6
Pages: 1509-1521
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Publication
First Author: Zhang Y
Year: 2023
Journal: Cell Metab
Title: Dietary fructose-mediated adipocyte metabolism drives antitumor CD8(+) T?cell responses.
Volume: 35
Issue: 12
Pages: 2107-2118.e6
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Publication
First Author: Van de Velde LA
Year: 2017
Journal: J Biol Chem
Title: T Cells Encountering Myeloid Cells Programmed for Amino Acid-dependent Immunosuppression Use Rictor/mTORC2 Protein for Proliferative Checkpoint Decisions.
Volume: 292
Issue: 1
Pages: 15-30
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Publication  
First Author: Huang B
Year: 2016
Journal: Nat Commun
Title: Osteoblasts secrete Cxcl9 to regulate angiogenesis in bone.
Volume: 7
Pages: 13885
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Publication  
First Author: Yin N
Year: 2022
Journal: J Clin Invest
Title: SZT2 maintains hematopoietic stem cell homeostasis via nutrient-mediated mTORC1 regulation.
Volume: 132
Issue: 20
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Publication
First Author: Wang C
Year: 2015
Journal: Hepatology
Title: 4EBP1/eIF4E and p70S6K/RPS6 axes play critical and distinct roles in hepatocarcinogenesis driven by AKT and N-Ras proto-oncogenes in mice.
Volume: 61
Issue: 1
Pages: 200-13
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Publication
First Author: Feng P
Year: 2021
Journal: Theranostics
Title: The kinase PDK1 regulates regulatory T cell survival via controlling redox homeostasis.
Volume: 11
Issue: 19
Pages: 9503-9518
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Publication
First Author: Jiang M
Year: 2017
Journal: J Cell Biochem
Title: mTORC1 Signaling Promotes Limb Bud Cell Growth and Chondrogenesis.
Volume: 118
Issue: 4
Pages: 748-753
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Publication
First Author: Armour EA
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Cystogenesis and elongated primary cilia in Tsc1-deficient distal convoluted tubules.
Volume: 303
Issue: 4
Pages: F584-92
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Publication
First Author: Lu J
Year: 2018
Journal: J Bone Miner Res
Title: Positive-Feedback Regulation of Subchondral H-Type Vessel Formation by Chondrocyte Promotes Osteoarthritis Development in Mice.
Volume: 33
Issue: 5
Pages: 909-920
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Publication
First Author: Fukasawa K
Year: 2026
Journal: iScience
Title: Regulatory role of mTORC1 signaling in osteoblasts in acute myeloid leukemia progression and steady-state hematopoiesis.
Volume: 29
Issue: 1
Pages: 114533
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Publication
First Author: Artinian J
Year: 2019
Journal: J Neurosci
Title: Regulation of Hippocampal Memory by mTORC1 in Somatostatin Interneurons.
Volume: 39
Issue: 43
Pages: 8439-8456
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Publication
First Author: Xiong Z
Year: 2018
Journal: Biol Reprod
Title: Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis.
Volume: 99
Issue: 6
Pages: 1289-1302
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Publication
First Author: Gorre N
Year: 2014
Journal: PLoS One
Title: mTORC1 Signaling in oocytes is dispensable for the survival of primordial follicles and for female fertility.
Volume: 9
Issue: 10
Pages: e110491
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Publication
First Author: Gaudette BT
Year: 2020
Journal: Nat Commun
Title: mTORC1 coordinates an immediate unfolded protein response-related transcriptome in activated B cells preceding antibody secretion.
Volume: 11
Issue: 1
Pages: 723
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Publication  
First Author: Canaud G
Year: 2019
Journal: Sci Transl Med
Title: Cyclin G1 and TASCC regulate kidney epithelial cell G(2)-M arrest and fibrotic maladaptive repair.
Volume: 11
Issue: 476
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Publication
First Author: Kim D
Year: 2020
Journal: Immunity
Title: Anti-inflammatory Roles of Glucocorticoids Are Mediated by Foxp3(+) Regulatory T Cells via a miR-342-Dependent Mechanism.
Volume: 53
Issue: 3
Pages: 581-596.e5
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Publication    
First Author: Covarrubias AJ
Year: 2016
Journal: Elife
Title: Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation.
Volume: 5
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Publication
First Author: Brown J
Year: 2011
Journal: J Biol Chem
Title: Mammalian target of rapamycin complex 2 (mTORC2) negatively regulates Toll-like receptor 4-mediated inflammatory response via FoxO1.
Volume: 286
Issue: 52
Pages: 44295-305
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Publication
First Author: Li M
Year: 2024
Journal: FASEB J
Title: mTORC2-AKT signaling to PFKFB2 activates glycolysis that enhances stemness and tumorigenicity of intestinal epithelial cells.
Volume: 38
Issue: 5
Pages: e23532
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Publication  
First Author: Eslamizade MJ
Year: 2026
Journal: Neuroscience
Title: Early postsynaptic potentiation in hippocampal somatostatin interneurons is mTORC1-dependent and disrupted in Fmr1(-/y) mice.
Volume: 593
Pages: 184-194
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Publication
First Author: Hu L
Year: 2026
Journal: Cell Mol Immunol
Title: Obesity disrupts ILC2 metabolic and functional homeostasis by inhibiting mTORC1 signaling.
Volume: 23
Issue: 3
Pages: 301-314
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Publication
First Author: Gan W
Year: 2020
Journal: Nat Cell Biol
Title: LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control.
Volume: 22
Issue: 2
Pages: 246-256
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Publication
First Author: Tripathy S
Year: 2013
Journal: J Lipid Res
Title: Elovl5 regulates the mTORC2-Akt-FOXO1 pathway by controlling hepatic cis-vaccenic acid synthesis in diet-induced obese mice.
Volume: 54
Issue: 1
Pages: 71-84
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Publication
First Author: Akg?l S
Year: 2018
Journal: Cell Rep
Title: Opposing Tumor-Promoting and -Suppressive Functions of Rictor/mTORC2 Signaling in Adult Glioma and Pediatric SHH Medulloblastoma.
Volume: 24
Issue: 2
Pages: 463-478.e5
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Publication
First Author: Martin SK
Year: 2018
Journal: Sci Rep
Title: mTORC1 plays an important role in osteoblastic regulation of B-lymphopoiesis.
Volume: 8
Issue: 1
Pages: 14501
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Publication
First Author: Kouloulia S
Year: 2019
Journal: Cell Rep
Title: Raptor-Mediated Proteasomal Degradation of Deamidated 4E-BP2 Regulates Postnatal Neuronal Translation and NF-?B Activity.
Volume: 29
Issue: 11
Pages: 3620-3635.e7
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Publication
First Author: Ye M
Year: 2023
Journal: Invest Ophthalmol Vis Sci
Title: TBK1 Knockdown Alleviates Axonal Transport Deficits in Retinal Ganglion Cells Via mTORC1 Activation in a Retinal Damage Mouse Model.
Volume: 64
Issue: 10
Pages: 1
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Publication
First Author: Trost M
Year: 2009
Journal: Immunity
Title: The phagosomal proteome in interferon-gamma-activated macrophages.
Volume: 30
Issue: 1
Pages: 143-54
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Publication  
First Author: Yang M
Year: 2016
Journal: Nat Commun
Title: NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.
Volume: 7
Pages: 12730
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Publication
First Author: Venkatesh A
Year: 2015
Journal: J Clin Invest
Title: Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice.
Volume: 125
Issue: 4
Pages: 1446-58
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Publication
First Author: Nobs SP
Year: 2015
Journal: Immunity
Title: PI3-Kinase-? Has a Distinct and Essential Role in Lung-Specific Dendritic Cell Development.
Volume: 43
Issue: 4
Pages: 674-89
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Publication
First Author: Hung CM
Year: 2014
Journal: Cell Rep
Title: Rictor/mTORC2 loss in the Myf5 lineage reprograms brown fat metabolism and protects mice against obesity and metabolic disease.
Volume: 8
Issue: 1
Pages: 256-71
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Publication
First Author: Rosenlehner T
Year: 2024
Journal: Sci Signal
Title: Reciprocal regulation of mTORC1 signaling and ribosomal biosynthesis determines cell cycle progression in activated T cells.
Volume: 17
Issue: 859
Pages: eadi8753
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Publication
First Author: Xia H
Year: 2020
Journal: Cell Rep
Title: Evasion of Type I Interferon by SARS-CoV-2.
Volume: 33
Issue: 1
Pages: 108234
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Protein
Organism: Mus musculus/domesticus
Length: 3658  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 525  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 392  
Fragment?: false
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Publication
First Author: Malik TH
Year: 2001
Journal: EMBO J
Title: Transcriptional repression and developmental functions of the atypical vertebrate GATA protein TRPS1.
Volume: 20
Issue: 7
Pages: 1715-25
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First Author: Wolff NC
Year: 2011
Journal: Mol Cell Biol
Title: Cell-type-dependent regulation of mTORC1 by REDD1 and the tumor suppressors TSC1/TSC2 and LKB1 in response to hypoxia.
Volume: 31
Issue: 9
Pages: 1870-84
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Publication
First Author: Feng D
Year: 2015
Journal: PLoS One
Title: mTORC1 Down-Regulates Cyclin-Dependent Kinase 8 (CDK8) and Cyclin C (CycC).
Volume: 10
Issue: 6
Pages: e0126240
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Publication
First Author: Signer RA
Year: 2014
Journal: Nature
Title: Haematopoietic stem cells require a highly regulated protein synthesis rate.
Volume: 509
Issue: 7498
Pages: 49-54
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Publication
First Author: Mastrangelo A
Year: 2025
Journal: Nature
Title: Imidazole propionate is a driver and therapeutic target in atherosclerosis.
Volume: 645
Issue: 8079
Pages: 254-261
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Publication
First Author: Hooshmandi M
Year: 2023
Journal: Neuron
Title: Excitatory neuron-specific suppression of the integrated stress response contributes to autism-related phenotypes in fragile X syndrome.
Volume: 111
Issue: 19
Pages: 3028-3040.e6
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Publication
First Author: Shrestha S
Year: 2015
Journal: Nat Immunol
Title: Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses.
Volume: 16
Issue: 2
Pages: 178-87
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Publication
First Author: Zhu X
Year: 2024
Journal: Nat Commun
Title: The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness.
Volume: 15
Issue: 1
Pages: 10163
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Publication
First Author: Ai D
Year: 2014
Journal: Circ Res
Title: Disruption of mammalian target of rapamycin complex 1 in macrophages decreases chemokine gene expression and atherosclerosis.
Volume: 114
Issue: 10
Pages: 1576-84
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Publication
First Author: Yi W
Year: 2017
Journal: Nat Commun
Title: The mTORC1-4E-BP-eIF4E axis controls de novo Bcl6 protein synthesis in T cells and systemic autoimmunity.
Volume: 8
Issue: 1
Pages: 254
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Publication
First Author: Charbonnier LM
Year: 2015
Journal: Nat Immunol
Title: Control of peripheral tolerance by regulatory T cell-intrinsic Notch signaling.
Volume: 16
Issue: 11
Pages: 1162-73
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Publication
First Author: Karmaus PWF
Year: 2019
Journal: Nature
Title: Metabolic heterogeneity underlies reciprocal fates of T(H)17 cell stemness and plasticity.
Volume: 565
Issue: 7737
Pages: 101-105
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Publication  
First Author: Huynh H
Year: 2018
Journal: Commun Biol
Title: mTORC1 impedes osteoclast differentiation via calcineurin and NFATc1.
Volume: 1
Pages: 29
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Publication
First Author: Hinden L
Year: 2022
Journal: Nat Commun
Title: Opposite physiological and pathological mTORC1-mediated roles of the CB1 receptor in regulating renal tubular function.
Volume: 13
Issue: 1
Pages: 1783
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Publication
First Author: Yang T
Year: 2016
Journal: Cell Mol Immunol
Title: TSC1 controls IL-1? expression in macrophages via mTORC1-dependent C/EBP? pathway.
Volume: 13
Issue: 5
Pages: 640-50
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Publication
First Author: Singh BK
Year: 2016
Journal: J Biol Chem
Title: Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition.
Volume: 291
Issue: 1
Pages: 198-214
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Publication  
First Author: Jones I
Year: 2019
Journal: Biol Open
Title: Reduced mTORC1-signalling in retinal progenitor cells leads to visual pathway dysfunction.
Volume: 8
Issue: 8
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Publication  
First Author: Guo Y
Year: 2021
Journal: Front Cell Dev Biol
Title: Francisella novicida Mutant XWK4 Triggers Robust Inflammasome Activation Favoring Infection.
Volume: 9
Pages: 743335
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Publication
First Author: Zhao X
Year: 2025
Journal: Oncogene
Title: Rictor orchestrates ?-catenin/FOXO balance by maintaining redox homeostasis during development of ovarian cancer.
Volume: 44
Issue: 23
Pages: 1820-1832
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Publication
First Author: Fu X
Year: 2018
Journal: J Clin Invest
Title: Tuberous sclerosis complex-mediated mTORC1 overactivation promotes age-related hearing loss.
Volume: 128
Issue: 11
Pages: 4938-4955
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Publication
First Author: Huang H
Year: 2019
Journal: Cell Death Dis
Title: AKT-dependent and -independent pathways mediate PTEN deletion-induced CNS axon regeneration.
Volume: 10
Issue: 3
Pages: 203
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Publication
First Author: Gu Y
Year: 2011
Journal: Diabetes
Title: Rictor/mTORC2 is essential for maintaining a balance between beta-cell proliferation and cell size.
Volume: 60
Issue: 3
Pages: 827-37
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Publication
First Author: Grahammer F
Year: 2024
Journal: Kidney Int
Title: Cyclin-dependent kinase 4 drives cystic kidney disease in the absence of mTORC1 signaling activity.
Volume: 106
Issue: 5
Pages: 856-869
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Publication  
First Author: Trevi?o-Villarreal JH
Year: 2018
Journal: JCI Insight
Title: Dietary protein restriction reduces circulating VLDL triglyceride levels via CREBH-APOA5-dependent and -independent mechanisms.
Volume: 3
Issue: 21
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Publication
First Author: Gosis BS
Year: 2022
Journal: Science
Title: Inhibition of nonalcoholic fatty liver disease in mice by selective inhibition of mTORC1.
Volume: 376
Issue: 6590
Pages: eabf8271
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Publication
First Author: Wan M
Year: 2011
Journal: Cell Metab
Title: Postprandial hepatic lipid metabolism requires signaling through Akt2 independent of the transcription factors FoxA2, FoxO1, and SREBP1c.
Volume: 14
Issue: 4
Pages: 516-27
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Publication
First Author: Zhang H
Year: 2014
Journal: Curr Biol
Title: Somatic cells initiate primordial follicle activation and govern the development of dormant oocytes in mice.
Volume: 24
Issue: 21
Pages: 2501-8
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Publication
First Author: Heikamp EB
Year: 2014
Journal: Nat Immunol
Title: The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex.
Volume: 15
Issue: 5
Pages: 457-64
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Publication
First Author: Liu C
Year: 2021
Journal: Sci Adv
Title: Glycogen synthase kinase 3 drives thymocyte egress by suppressing ?-catenin activation of Akt.
Volume: 7
Issue: 41
Pages: eabg6262
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Publication
First Author: Ruegsegger C
Year: 2016
Journal: Neuron
Title: Impaired mTORC1-Dependent Expression of Homer-3 Influences SCA1 Pathophysiology.
Volume: 89
Issue: 1
Pages: 129-46
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Publication
First Author: Xiao M
Year: 2017
Journal: Blood
Title: Osteoblasts support megakaryopoiesis through production of interleukin-9.
Volume: 129
Issue: 24
Pages: 3196-3209
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