| Type |
Details |
Score |
| Publication |
| First Author: |
Arif A |
| Year: |
2017 |
| Journal: |
Nature |
| Title: |
EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice. |
| Volume: |
542 |
| Issue: |
7641 |
| Pages: |
357-361 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yu X |
| Year: |
2018 |
| Journal: |
J Exp Med |
| Title: |
Metabolic control of regulatory T cell stability and function by TRAF3IP3 at the lysosome. |
| Volume: |
215 |
| Issue: |
9 |
| Pages: |
2463-2476 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ruiz A |
| Year: |
2018 |
| Journal: |
Sci Rep |
| Title: |
Over-expression of a retinol dehydrogenase (SRP35/DHRS7C) in skeletal muscle activates mTORC2, enhances glucose metabolism and muscle performance. |
| Volume: |
8 |
| Issue: |
1 |
| Pages: |
636 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Meng ZX |
| Year: |
2014 |
| Journal: |
Diabetes |
| Title: |
The Baf60c/Deptor pathway links skeletal muscle inflammation to glucose homeostasis in obesity. |
| Volume: |
63 |
| Issue: |
5 |
| Pages: |
1533-45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yan J |
| Year: |
2018 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Activation of autophagy rescues synaptic and cognitive deficits in fragile X mice. |
| Volume: |
115 |
| Issue: |
41 |
| Pages: |
E9707-E9716 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gerlach BD |
| Year: |
2021 |
| Journal: |
Cell Metab |
| Title: |
Efferocytosis induces macrophage proliferation to help resolve tissue injury. |
| Volume: |
33 |
| Issue: |
12 |
| Pages: |
2445-2463.e8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Everts B |
| Year: |
2014 |
| Journal: |
Nat Immunol |
| Title: |
TLR-driven early glycolytic reprogramming via the kinases TBK1-IKK? supports the anabolic demands of dendritic cell activation. |
| Volume: |
15 |
| Issue: |
4 |
| Pages: |
323-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Opejin A |
| Year: |
2020 |
| Journal: |
Cell Rep |
| Title: |
A Two-Step Process of Effector Programming Governs CD4(+) T Cell Fate Determination Induced by Antigenic Activation in the Steady State. |
| Volume: |
33 |
| Issue: |
8 |
| Pages: |
108424 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Newton RH |
| Year: |
2018 |
| Journal: |
Nat Immunol |
| Title: |
Maintenance of CD4 T cell fitness through regulation of Foxo1. |
| Volume: |
19 |
| Issue: |
8 |
| Pages: |
838-848 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Do MH |
| Year: |
2023 |
| Journal: |
Immunity |
| Title: |
Reprogramming tumor-associated macrophages to outcompete endovascular endothelial progenitor cells and suppress tumor neoangiogenesis. |
| Volume: |
56 |
| Issue: |
11 |
| Pages: |
2555-2569.e5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang D |
| Year: |
2025 |
| Journal: |
Nat Commun |
| Title: |
mTORC1 signaling in group 2 innate lymphoid cells coordinates neuro-immune crosstalk in allergic lung inflammation. |
| Volume: |
17 |
| Issue: |
1 |
| Pages: |
62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Magee JA |
| Year: |
2012 |
| Journal: |
Cell Stem Cell |
| Title: |
Temporal changes in PTEN and mTORC2 regulation of hematopoietic stem cell self-renewal and leukemia suppression. |
| Volume: |
11 |
| Issue: |
3 |
| Pages: |
415-28 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang S |
| Year: |
2023 |
| Journal: |
J Clin Invest |
| Title: |
The UBE2C/CDH1/DEPTOR axis is an oncogene and tumor suppressor cascade in lung cancer cells. |
| Volume: |
133 |
| Issue: |
4 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kogot-Levin A |
| Year: |
2020 |
| Journal: |
Cell Rep |
| Title: |
Proximal Tubule mTORC1 Is a Central Player in the Pathophysiology of Diabetic Nephropathy and Its Correction by SGLT2 Inhibitors. |
| Volume: |
32 |
| Issue: |
4 |
| Pages: |
107954 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Riahi Y |
| Year: |
2023 |
| Journal: |
Diabetologia |
| Title: |
Hyperglucagonaemia in diabetes: altered amino acid metabolism triggers mTORC1 activation, which drives glucagon production. |
| Volume: |
66 |
| Issue: |
10 |
| Pages: |
1925-1942 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang X |
| Year: |
2018 |
| Journal: |
Cell Rep |
| Title: |
Adipose mTORC1 Suppresses Prostaglandin Signaling and Beige Adipogenesis via the CRTC2-COX-2 Pathway. |
| Volume: |
24 |
| Issue: |
12 |
| Pages: |
3180-3193 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Haller S |
| Year: |
2017 |
| Journal: |
Cell Stem Cell |
| Title: |
mTORC1 Activation during Repeated Regeneration Impairs Somatic Stem Cell Maintenance. |
| Volume: |
21 |
| Issue: |
6 |
| Pages: |
806-818.e5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bohin N |
| Year: |
2020 |
| Journal: |
Cell Mol Gastroenterol Hepatol |
| Title: |
Insulin-like Growth Factor-1 and mTORC1 Signaling Promote the Intestinal Regenerative Response After Irradiation Injury. |
| Volume: |
10 |
| Issue: |
4 |
| Pages: |
797-810 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Meng ZX |
| Year: |
2017 |
| Journal: |
Mol Cell |
| Title: |
Glucose Sensing by Skeletal Myocytes Couples Nutrient Signaling to Systemic Homeostasis. |
| Volume: |
66 |
| Issue: |
3 |
| Pages: |
332-344.e4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Garc?a-Gil A |
| Year: |
2018 |
| Journal: |
Virulence |
| Title: |
SopB activates the Akt-YAP pathway to promote Salmonella survival within B cells. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
1390-1402 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huang L |
| Year: |
2017 |
| Journal: |
PLoS Biol |
| Title: |
Rictor positively regulates B cell receptor signaling by modulating actin reorganization via ezrin. |
| Volume: |
15 |
| Issue: |
8 |
| Pages: |
e2001750 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Gan Z |
| Year: |
2024 |
| Journal: |
Sci Bull (Beijing) |
| Title: |
Excitatory amino acid transporter supports inflammatory macrophage responses. |
| Volume: |
69 |
| Issue: |
15 |
| Pages: |
2405-2419 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Perumalsamy LR |
| Year: |
2012 |
| Journal: |
Sci Signal |
| Title: |
Distinct spatial and molecular features of notch pathway assembly in regulatory T cells. |
| Volume: |
5 |
| Issue: |
234 |
| Pages: |
ra53 |
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•
•
•
•
•
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| Publication |
| First Author: |
Lee JH |
| Year: |
2018 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
SREBP-1a-stimulated lipid synthesis is required for macrophage phagocytosis downstream of TLR4-directed mTORC1. |
| Volume: |
115 |
| Issue: |
52 |
| Pages: |
E12228-E12234 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Xiong X |
| Year: |
2025 |
| Journal: |
Cell Death Differ |
| Title: |
DEPTOR suppresses lymphomagenesis by promoting EGFR degradation via HUWE1 E3 ligase. |
| Volume: |
32 |
| Issue: |
10 |
| Pages: |
1820-1832 |
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•
•
•
•
•
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| Publication |
| First Author: |
Hua C |
| Year: |
2014 |
| Journal: |
Exp Hematol |
| Title: |
Rictor/mammalian target of rapamycin 2 regulates the development of Notch1 induced murine T-cell acute lymphoblastic leukemia via forkhead box O3. |
| Volume: |
42 |
| Issue: |
12 |
| Pages: |
1031-40.e1-4 |
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•
•
•
•
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| Publication |
| First Author: |
Bridges CR |
| Year: |
2017 |
| Journal: |
Sci Rep |
| Title: |
USP9X deubiquitylating enzyme maintains RAPTOR protein levels, mTORC1 signalling and proliferation in neural progenitors. |
| Volume: |
7 |
| Issue: |
1 |
| Pages: |
391 |
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•
•
•
•
•
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| First Author: |
Hu Y |
| Year: |
2018 |
| Journal: |
J Biol Chem |
| Title: |
Fructose and glucose can regulate mammalian target of rapamycin complex 1 and lipogenic gene expression via distinct pathways. |
| Volume: |
293 |
| Issue: |
6 |
| Pages: |
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•
•
•
•
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| First Author: |
He A |
| Year: |
2020 |
| Journal: |
Mol Cell |
| Title: |
Acetyl-CoA Derived from Hepatic Peroxisomal ?-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 Activation. |
| Volume: |
79 |
| Issue: |
1 |
| Pages: |
30-42.e4 |
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•
•
•
•
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| First Author: |
Canaud G |
| Year: |
2013 |
| Journal: |
Nat Med |
| Title: |
AKT2 is essential to maintain podocyte viability and function during chronic kidney disease. |
| Volume: |
19 |
| Issue: |
10 |
| Pages: |
1288-96 |
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•
•
•
•
•
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| Publication |
| First Author: |
Uehara K |
| Year: |
2024 |
| Journal: |
J Clin Invest |
| Title: |
mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b. |
| Volume: |
134 |
| Issue: |
7 |
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•
•
•
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| First Author: |
Menk AV |
| Year: |
2018 |
| Journal: |
Cell Rep |
| Title: |
Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions. |
| Volume: |
22 |
| Issue: |
6 |
| Pages: |
1509-1521 |
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•
•
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| First Author: |
Zhang Y |
| Year: |
2023 |
| Journal: |
Cell Metab |
| Title: |
Dietary fructose-mediated adipocyte metabolism drives antitumor CD8(+) T?cell responses. |
| Volume: |
35 |
| Issue: |
12 |
| Pages: |
2107-2118.e6 |
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•
•
•
•
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| First Author: |
Van de Velde LA |
| Year: |
2017 |
| Journal: |
J Biol Chem |
| Title: |
T Cells Encountering Myeloid Cells Programmed for Amino Acid-dependent Immunosuppression Use Rictor/mTORC2 Protein for Proliferative Checkpoint Decisions. |
| Volume: |
292 |
| Issue: |
1 |
| Pages: |
15-30 |
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•
•
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| First Author: |
Huang B |
| Year: |
2016 |
| Journal: |
Nat Commun |
| Title: |
Osteoblasts secrete Cxcl9 to regulate angiogenesis in bone. |
| Volume: |
7 |
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13885 |
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| First Author: |
Yin N |
| Year: |
2022 |
| Journal: |
J Clin Invest |
| Title: |
SZT2 maintains hematopoietic stem cell homeostasis via nutrient-mediated mTORC1 regulation. |
| Volume: |
132 |
| Issue: |
20 |
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| First Author: |
Wang C |
| Year: |
2015 |
| Journal: |
Hepatology |
| Title: |
4EBP1/eIF4E and p70S6K/RPS6 axes play critical and distinct roles in hepatocarcinogenesis driven by AKT and N-Ras proto-oncogenes in mice. |
| Volume: |
61 |
| Issue: |
1 |
| Pages: |
200-13 |
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| First Author: |
Feng P |
| Year: |
2021 |
| Journal: |
Theranostics |
| Title: |
The kinase PDK1 regulates regulatory T cell survival via controlling redox homeostasis. |
| Volume: |
11 |
| Issue: |
19 |
| Pages: |
9503-9518 |
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| First Author: |
Jiang M |
| Year: |
2017 |
| Journal: |
J Cell Biochem |
| Title: |
mTORC1 Signaling Promotes Limb Bud Cell Growth and Chondrogenesis. |
| Volume: |
118 |
| Issue: |
4 |
| Pages: |
748-753 |
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•
•
•
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| First Author: |
Armour EA |
| Year: |
2012 |
| Journal: |
Am J Physiol Renal Physiol |
| Title: |
Cystogenesis and elongated primary cilia in Tsc1-deficient distal convoluted tubules. |
| Volume: |
303 |
| Issue: |
4 |
| Pages: |
F584-92 |
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| First Author: |
Lu J |
| Year: |
2018 |
| Journal: |
J Bone Miner Res |
| Title: |
Positive-Feedback Regulation of Subchondral H-Type Vessel Formation by Chondrocyte Promotes Osteoarthritis Development in Mice. |
| Volume: |
33 |
| Issue: |
5 |
| Pages: |
909-920 |
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•
•
•
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| First Author: |
Fukasawa K |
| Year: |
2026 |
| Journal: |
iScience |
| Title: |
Regulatory role of mTORC1 signaling in osteoblasts in acute myeloid leukemia progression and steady-state hematopoiesis. |
| Volume: |
29 |
| Issue: |
1 |
| Pages: |
114533 |
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•
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| First Author: |
Artinian J |
| Year: |
2019 |
| Journal: |
J Neurosci |
| Title: |
Regulation of Hippocampal Memory by mTORC1 in Somatostatin Interneurons. |
| Volume: |
39 |
| Issue: |
43 |
| Pages: |
8439-8456 |
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•
•
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| First Author: |
Xiong Z |
| Year: |
2018 |
| Journal: |
Biol Reprod |
| Title: |
Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis. |
| Volume: |
99 |
| Issue: |
6 |
| Pages: |
1289-1302 |
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| First Author: |
Gorre N |
| Year: |
2014 |
| Journal: |
PLoS One |
| Title: |
mTORC1 Signaling in oocytes is dispensable for the survival of primordial follicles and for female fertility. |
| Volume: |
9 |
| Issue: |
10 |
| Pages: |
e110491 |
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•
•
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| First Author: |
Gaudette BT |
| Year: |
2020 |
| Journal: |
Nat Commun |
| Title: |
mTORC1 coordinates an immediate unfolded protein response-related transcriptome in activated B cells preceding antibody secretion. |
| Volume: |
11 |
| Issue: |
1 |
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| First Author: |
Canaud G |
| Year: |
2019 |
| Journal: |
Sci Transl Med |
| Title: |
Cyclin G1 and TASCC regulate kidney epithelial cell G(2)-M arrest and fibrotic maladaptive repair. |
| Volume: |
11 |
| Issue: |
476 |
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| First Author: |
Kim D |
| Year: |
2020 |
| Journal: |
Immunity |
| Title: |
Anti-inflammatory Roles of Glucocorticoids Are Mediated by Foxp3(+) Regulatory T Cells via a miR-342-Dependent Mechanism. |
| Volume: |
53 |
| Issue: |
3 |
| Pages: |
581-596.e5 |
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•
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| First Author: |
Covarrubias AJ |
| Year: |
2016 |
| Journal: |
Elife |
| Title: |
Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation. |
| Volume: |
5 |
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| First Author: |
Brown J |
| Year: |
2011 |
| Journal: |
J Biol Chem |
| Title: |
Mammalian target of rapamycin complex 2 (mTORC2) negatively regulates Toll-like receptor 4-mediated inflammatory response via FoxO1. |
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286 |
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| First Author: |
Li M |
| Year: |
2024 |
| Journal: |
FASEB J |
| Title: |
mTORC2-AKT signaling to PFKFB2 activates glycolysis that enhances stemness and tumorigenicity of intestinal epithelial cells. |
| Volume: |
38 |
| Issue: |
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e23532 |
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| First Author: |
Eslamizade MJ |
| Year: |
2026 |
| Journal: |
Neuroscience |
| Title: |
Early postsynaptic potentiation in hippocampal somatostatin interneurons is mTORC1-dependent and disrupted in Fmr1(-/y) mice. |
| Volume: |
593 |
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| First Author: |
Hu L |
| Year: |
2026 |
| Journal: |
Cell Mol Immunol |
| Title: |
Obesity disrupts ILC2 metabolic and functional homeostasis by inhibiting mTORC1 signaling. |
| Volume: |
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| Issue: |
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| First Author: |
Gan W |
| Year: |
2020 |
| Journal: |
Nat Cell Biol |
| Title: |
LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control. |
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Tripathy S |
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J Lipid Res |
| Title: |
Elovl5 regulates the mTORC2-Akt-FOXO1 pathway by controlling hepatic cis-vaccenic acid synthesis in diet-induced obese mice. |
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Akg?l S |
| Year: |
2018 |
| Journal: |
Cell Rep |
| Title: |
Opposing Tumor-Promoting and -Suppressive Functions of Rictor/mTORC2 Signaling in Adult Glioma and Pediatric SHH Medulloblastoma. |
| Volume: |
24 |
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463-478.e5 |
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| First Author: |
Martin SK |
| Year: |
2018 |
| Journal: |
Sci Rep |
| Title: |
mTORC1 plays an important role in osteoblastic regulation of B-lymphopoiesis. |
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Kouloulia S |
| Year: |
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Cell Rep |
| Title: |
Raptor-Mediated Proteasomal Degradation of Deamidated 4E-BP2 Regulates Postnatal Neuronal Translation and NF-?B Activity. |
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| Year: |
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Invest Ophthalmol Vis Sci |
| Title: |
TBK1 Knockdown Alleviates Axonal Transport Deficits in Retinal Ganglion Cells Via mTORC1 Activation in a Retinal Damage Mouse Model. |
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Trost M |
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Immunity |
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The phagosomal proteome in interferon-gamma-activated macrophages. |
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Nat Commun |
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NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation. |
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Venkatesh A |
| Year: |
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| Journal: |
J Clin Invest |
| Title: |
Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice. |
| Volume: |
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Immunity |
| Title: |
PI3-Kinase-? Has a Distinct and Essential Role in Lung-Specific Dendritic Cell Development. |
| Volume: |
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| Year: |
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| Journal: |
Cell Rep |
| Title: |
Rictor/mTORC2 loss in the Myf5 lineage reprograms brown fat metabolism and protects mice against obesity and metabolic disease. |
| Volume: |
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Sci Signal |
| Title: |
Reciprocal regulation of mTORC1 signaling and ribosomal biosynthesis determines cell cycle progression in activated T cells. |
| Volume: |
17 |
| Issue: |
859 |
| Pages: |
eadi8753 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xia H |
| Year: |
2020 |
| Journal: |
Cell Rep |
| Title: |
Evasion of Type I Interferon by SARS-CoV-2. |
| Volume: |
33 |
| Issue: |
1 |
| Pages: |
108234 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
3658
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
525
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
392
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Malik TH |
| Year: |
2001 |
| Journal: |
EMBO J |
| Title: |
Transcriptional repression and developmental functions of the atypical vertebrate GATA protein TRPS1. |
| Volume: |
20 |
| Issue: |
7 |
| Pages: |
1715-25 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Wolff NC |
| Year: |
2011 |
| Journal: |
Mol Cell Biol |
| Title: |
Cell-type-dependent regulation of mTORC1 by REDD1 and the tumor suppressors TSC1/TSC2 and LKB1 in response to hypoxia. |
| Volume: |
31 |
| Issue: |
9 |
| Pages: |
1870-84 |
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•
•
•
•
•
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| Publication |
| First Author: |
Feng D |
| Year: |
2015 |
| Journal: |
PLoS One |
| Title: |
mTORC1 Down-Regulates Cyclin-Dependent Kinase 8 (CDK8) and Cyclin C (CycC). |
| Volume: |
10 |
| Issue: |
6 |
| Pages: |
e0126240 |
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•
•
•
•
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| Publication |
| First Author: |
Signer RA |
| Year: |
2014 |
| Journal: |
Nature |
| Title: |
Haematopoietic stem cells require a highly regulated protein synthesis rate. |
| Volume: |
509 |
| Issue: |
7498 |
| Pages: |
49-54 |
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•
•
•
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| Publication |
| First Author: |
Mastrangelo A |
| Year: |
2025 |
| Journal: |
Nature |
| Title: |
Imidazole propionate is a driver and therapeutic target in atherosclerosis. |
| Volume: |
645 |
| Issue: |
8079 |
| Pages: |
254-261 |
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•
•
•
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| Publication |
| First Author: |
Hooshmandi M |
| Year: |
2023 |
| Journal: |
Neuron |
| Title: |
Excitatory neuron-specific suppression of the integrated stress response contributes to autism-related phenotypes in fragile X syndrome. |
| Volume: |
111 |
| Issue: |
19 |
| Pages: |
3028-3040.e6 |
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•
•
•
|
| Publication |
| First Author: |
Shrestha S |
| Year: |
2015 |
| Journal: |
Nat Immunol |
| Title: |
Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses. |
| Volume: |
16 |
| Issue: |
2 |
| Pages: |
178-87 |
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•
•
•
•
•
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| Publication |
| First Author: |
Zhu X |
| Year: |
2024 |
| Journal: |
Nat Commun |
| Title: |
The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness. |
| Volume: |
15 |
| Issue: |
1 |
| Pages: |
10163 |
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•
•
•
|
| Publication |
| First Author: |
Ai D |
| Year: |
2014 |
| Journal: |
Circ Res |
| Title: |
Disruption of mammalian target of rapamycin complex 1 in macrophages decreases chemokine gene expression and atherosclerosis. |
| Volume: |
114 |
| Issue: |
10 |
| Pages: |
1576-84 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yi W |
| Year: |
2017 |
| Journal: |
Nat Commun |
| Title: |
The mTORC1-4E-BP-eIF4E axis controls de novo Bcl6 protein synthesis in T cells and systemic autoimmunity. |
| Volume: |
8 |
| Issue: |
1 |
| Pages: |
254 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Charbonnier LM |
| Year: |
2015 |
| Journal: |
Nat Immunol |
| Title: |
Control of peripheral tolerance by regulatory T cell-intrinsic Notch signaling. |
| Volume: |
16 |
| Issue: |
11 |
| Pages: |
1162-73 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Karmaus PWF |
| Year: |
2019 |
| Journal: |
Nature |
| Title: |
Metabolic heterogeneity underlies reciprocal fates of T(H)17 cell stemness and plasticity. |
| Volume: |
565 |
| Issue: |
7737 |
| Pages: |
101-105 |
|
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•
•
•
•
|
| Publication |
| First Author: |
Huynh H |
| Year: |
2018 |
| Journal: |
Commun Biol |
| Title: |
mTORC1 impedes osteoclast differentiation via calcineurin and NFATc1. |
| Volume: |
1 |
|
| Pages: |
29 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hinden L |
| Year: |
2022 |
| Journal: |
Nat Commun |
| Title: |
Opposite physiological and pathological mTORC1-mediated roles of the CB1 receptor in regulating renal tubular function. |
| Volume: |
13 |
| Issue: |
1 |
| Pages: |
1783 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yang T |
| Year: |
2016 |
| Journal: |
Cell Mol Immunol |
| Title: |
TSC1 controls IL-1? expression in macrophages via mTORC1-dependent C/EBP? pathway. |
| Volume: |
13 |
| Issue: |
5 |
| Pages: |
640-50 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Singh BK |
| Year: |
2016 |
| Journal: |
J Biol Chem |
| Title: |
Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition. |
| Volume: |
291 |
| Issue: |
1 |
| Pages: |
198-214 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jones I |
| Year: |
2019 |
| Journal: |
Biol Open |
| Title: |
Reduced mTORC1-signalling in retinal progenitor cells leads to visual pathway dysfunction. |
| Volume: |
8 |
| Issue: |
8 |
|
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•
•
•
•
•
|
| Publication |
| First Author: |
Guo Y |
| Year: |
2021 |
| Journal: |
Front Cell Dev Biol |
| Title: |
Francisella novicida Mutant XWK4 Triggers Robust Inflammasome Activation Favoring Infection. |
| Volume: |
9 |
|
| Pages: |
743335 |
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•
•
•
•
|
| Publication |
| First Author: |
Zhao X |
| Year: |
2025 |
| Journal: |
Oncogene |
| Title: |
Rictor orchestrates ?-catenin/FOXO balance by maintaining redox homeostasis during development of ovarian cancer. |
| Volume: |
44 |
| Issue: |
23 |
| Pages: |
1820-1832 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fu X |
| Year: |
2018 |
| Journal: |
J Clin Invest |
| Title: |
Tuberous sclerosis complex-mediated mTORC1 overactivation promotes age-related hearing loss. |
| Volume: |
128 |
| Issue: |
11 |
| Pages: |
4938-4955 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huang H |
| Year: |
2019 |
| Journal: |
Cell Death Dis |
| Title: |
AKT-dependent and -independent pathways mediate PTEN deletion-induced CNS axon regeneration. |
| Volume: |
10 |
| Issue: |
3 |
| Pages: |
203 |
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•
•
•
•
|
| Publication |
| First Author: |
Gu Y |
| Year: |
2011 |
| Journal: |
Diabetes |
| Title: |
Rictor/mTORC2 is essential for maintaining a balance between beta-cell proliferation and cell size. |
| Volume: |
60 |
| Issue: |
3 |
| Pages: |
827-37 |
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•
•
|
| Publication |
| First Author: |
Grahammer F |
| Year: |
2024 |
| Journal: |
Kidney Int |
| Title: |
Cyclin-dependent kinase 4 drives cystic kidney disease in the absence of mTORC1 signaling activity. |
| Volume: |
106 |
| Issue: |
5 |
| Pages: |
856-869 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Trevi?o-Villarreal JH |
| Year: |
2018 |
| Journal: |
JCI Insight |
| Title: |
Dietary protein restriction reduces circulating VLDL triglyceride levels via CREBH-APOA5-dependent and -independent mechanisms. |
| Volume: |
3 |
| Issue: |
21 |
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•
•
•
•
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| Publication |
| First Author: |
Gosis BS |
| Year: |
2022 |
| Journal: |
Science |
| Title: |
Inhibition of nonalcoholic fatty liver disease in mice by selective inhibition of mTORC1. |
| Volume: |
376 |
| Issue: |
6590 |
| Pages: |
eabf8271 |
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•
•
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| Publication |
| First Author: |
Wan M |
| Year: |
2011 |
| Journal: |
Cell Metab |
| Title: |
Postprandial hepatic lipid metabolism requires signaling through Akt2 independent of the transcription factors FoxA2, FoxO1, and SREBP1c. |
| Volume: |
14 |
| Issue: |
4 |
| Pages: |
516-27 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang H |
| Year: |
2014 |
| Journal: |
Curr Biol |
| Title: |
Somatic cells initiate primordial follicle activation and govern the development of dormant oocytes in mice. |
| Volume: |
24 |
| Issue: |
21 |
| Pages: |
2501-8 |
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•
•
•
•
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| Publication |
| First Author: |
Heikamp EB |
| Year: |
2014 |
| Journal: |
Nat Immunol |
| Title: |
The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex. |
| Volume: |
15 |
| Issue: |
5 |
| Pages: |
457-64 |
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•
•
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| Publication |
| First Author: |
Liu C |
| Year: |
2021 |
| Journal: |
Sci Adv |
| Title: |
Glycogen synthase kinase 3 drives thymocyte egress by suppressing ?-catenin activation of Akt. |
| Volume: |
7 |
| Issue: |
41 |
| Pages: |
eabg6262 |
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•
•
•
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| Publication |
| First Author: |
Ruegsegger C |
| Year: |
2016 |
| Journal: |
Neuron |
| Title: |
Impaired mTORC1-Dependent Expression of Homer-3 Influences SCA1 Pathophysiology. |
| Volume: |
89 |
| Issue: |
1 |
| Pages: |
129-46 |
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•
•
•
•
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| Publication |
| First Author: |
Xiao M |
| Year: |
2017 |
| Journal: |
Blood |
| Title: |
Osteoblasts support megakaryopoiesis through production of interleukin-9. |
| Volume: |
129 |
| Issue: |
24 |
| Pages: |
3196-3209 |
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•
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