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Search results 501 to 600 out of 627 for Acly

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Type Details Score
Publication
37267106 | J:337945
First Author: Mocholi E
Year: 2023
Journal: Cell Rep
Title: Pyruvate metabolism controls chromatin remodeling during CD4(+) T cell activation.
Volume: 42
Issue: 6
Pages: 112583
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Publication
29415885 | J:290238
 
First Author: Imamura M
Year: 2018
Journal: JCI Insight
Title: RIPK3 promotes kidney fibrosis via AKT-dependent ATP citrate lyase.
Volume: 3
Issue: 3
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Publication
21281598 | J:171637
First Author: Moriya H
Year: 2011
Journal: Arch Biochem Biophys
Title: Secretion of three enzymes for fatty acid synthesis into mouse milk in association with fat globules, and rapid decrease of the secreted enzymes by treatment with rapamycin.
Volume: 508
Issue: 1
Pages: 87-92
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Publication
23897429 | J:205021
First Author: Londoño Gentile T
Year: 2013
Journal: Mol Cell Biol
Title: DNMT1 is regulated by ATP-citrate lyase and maintains methylation patterns during adipocyte differentiation.
Volume: 33
Issue: 19
Pages: 3864-78
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Publication
27582470 | J:238278
First Author: Karlstaedt A
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Oncometabolite d-2-hydroxyglutarate impairs α-ketoglutarate dehydrogenase and contractile function in rodent heart.
Volume: 113
Issue: 37
Pages: 10436-41
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Publication
30626590 | J:273222
First Author: Carrer A
Year: 2019
Journal: Cancer Discov
Title: Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis.
Volume: 9
Issue: 3
Pages: 416-435
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Publication
39471817 | J:361081
First Author: Rauckhorst AJ
Year: 2025
Journal: Cell Metab
Title: A hierarchical hepatic de novo lipogenesis substrate supply network utilizing pyruvate, acetate, and ketones.
Volume: 37
Issue: 1
Pages: 255-273.e6
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Publication
35069527 | J:331178
 
First Author: Lv N
Year: 2021
Journal: Front Immunol
Title: PP2Cδ Controls the Differentiation and Function of Dendritic Cells Through Regulating the NSD2/mTORC2/ACLY Pathway.
Volume: 12
Pages: 751409
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Publication
35316657 | J:333814
First Author: Hochrein SM
Year: 2022
Journal: Cell Metab
Title: The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming.
Volume: 34
Issue: 4
Pages: 516-532.e11
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Publication
27659423 | J:240465
First Author: Ortiz-Miranda S
Year: 2016
Journal: Am J Physiol Gastrointest Liver Physiol
Title: A novel transgenic mouse model of lysosomal storage disorder.
Volume: 311
Issue: 5
Pages: G903-G919
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Publication
23000407 | J:190090
First Author: Hasegawa S
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Acetoacetyl-CoA synthetase is essential for normal neuronal development.
Volume: 427
Issue: 2
Pages: 398-403
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Publication
8070621 | J:19568
First Author: Nomura M
Year: 1994
Journal: Differentiation
Title: Isolation and characterization of retinoic acid-inducible cDNA clones in F9 cells: one of the early inducible clones encodes a novel protein sharing several highly homologous regions with a Drosophila polyhomeotic protein.
Volume: 57
Issue: 1
Pages: 39-50
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Publication
38198889 | J:346073
First Author: Farhat B
Year: 2024
Journal: Dev Cell
Title: Understanding the cell fate and behavior of progenitors at the origin of the mouse cardiac mitral valve.
Volume: 59
Issue: 3
Pages: 339-350.e4
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Publication
24763339 | J:213234
First Author: Cho HH
Year: 2014
Journal: PLoS Genet
Title: Isl1 directly controls a cholinergic neuronal identity in the developing forebrain and spinal cord by forming cell type-specific complexes.
Volume: 10
Issue: 4
Pages: e1004280
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Publication
29203794 | J:286891
First Author: Sumi K
Year: 2017
Journal: Sci Rep
Title: Behavioral impairment in SHATI/NAT8L knockout mice via dysfunction of myelination development.
Volume: 7
Issue: 1
Pages: 16872
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Publication
- | J:344138
     
First Author: The Centre for Phenogenomics
Year: 2024
Journal: MGI Direct Data Submission
Title: Strains and alleles submitted by The Centre for Phenogenomics
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Publication
30658714 | J:272505
First Author: Catela C
Year: 2019
Journal: Neural Dev
Title: An ancient role for collier/Olf/Ebf (COE)-type transcription factors in axial motor neuron development.
Volume: 14
Issue: 1
Pages: 2
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Publication
18798549 | J:142567
First Author: Capellini TD
Year: 2008
Journal: Genesis
Title: Conservation of notochord gene expression across chordates: insights from the Leprecan gene family.
Volume: 46
Issue: 11
Pages: 683-96
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Publication
26508642 | J:227474
First Author: Fonseca TL
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity.
Volume: 112
Issue: 45
Pages: 14018-23
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Publication
31693883 | J:299602
First Author: Mayeuf-Louchart A
Year: 2019
Journal: Cell Rep
Title: Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation.
Volume: 29
Issue: 6
Pages: 1410-1418.e6
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Publication
26586428 | J:228946
First Author: Wei N
Year: 2015
Journal: Cell Rep
Title: SRSF10 Plays a Role in Myoblast Differentiation and Glucose Production via Regulation of Alternative Splicing.
Volume: 13
Issue: 8
Pages: 1647-57
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Publication
35863637 | J:327433
 
First Author: Song Z
Year: 2022
Journal: Mol Metab
Title: The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation.
Volume: 64
Pages: 101548
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Publication
26220403 | J:224441
 
First Author: Lim GE
Year: 2015
Journal: Nat Commun
Title: 14-3-3ζ coordinates adipogenesis of visceral fat.
Volume: 6
Pages: 7671
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Publication
11471062 | J:70827
First Author: Ehringer MA
Year: 2001
Journal: Mamm Genome
Title: High-throughput sequence identification of gene coding variants within alcohol-related QTLs.
Volume: 12
Issue: 8
Pages: 657-63
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Publication
30135482 | J:266255
First Author: Scavuzzo MA
Year: 2018
Journal: Nat Commun
Title: Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis.
Volume: 9
Issue: 1
Pages: 3356
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Publication
27215380 | J:236179
First Author: Bowman CE
Year: 2016
Journal: Mol Cell Biol
Title: Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.
Volume: 36
Issue: 15
Pages: 2089-104
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Publication
- | J:175597
     
First Author: Overbeek PA
Year: 2011
Journal: MGI Direct Data Submission
Title: Direct Data Submission for Overbeek Lentiviral Transgenic Lines
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Publication
27689697 | J:235644
First Author: Wu Y
Year: 2016
Journal: PLoS Genet
Title: Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury.
Volume: 12
Issue: 9
Pages: e1006355
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Publication
28245920 | J:240028
First Author: Bulusu V
Year: 2017
Journal: Dev Cell
Title: Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.
Volume: 40
Issue: 4
Pages: 331-341.e4
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Publication
15102471 | J:114108
First Author: Papin J
Year: 2004
Journal: Curr Opin Biotechnol
Title: Bioinformatics and cellular signaling.
Volume: 15
Issue: 1
Pages: 78-81
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Publication
- | J:147112
     
First Author: Taconic
Year: 2006
Journal: MGI Direct Data Submission
Title: Information obtained from Taconic website.
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
18554416 | J:139177
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
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Publication
18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
39251781 | J:360491
First Author: Zhang Y
Year: 2024
Journal: Cell Mol Immunol
Title: RBM25 is required to restrain inflammation via ACLY RNA splicing-dependent metabolism rewiring.
Volume: 21
Issue: 11
Pages: 1231-1250
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Interaction Experiment
Li K (2021)
Description: Hrd1-mediated ACLY ubiquitination alleviate NAFLD in db/db mice.
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Allele
Acly<Gt(NPX098)Byg> | MGI:3036686
Name: ATP citrate lyase; gene trap NPX098, BayGenomics
Allele Type: Gene trapped
Attribute String: Null/knockout, Reporter
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Allele
Acly<em1Smoc> | MGI:7288071
Name: ATP citrate lyase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Acly<em2Smoc> | MGI:7288072
Name: ATP citrate lyase; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:6474716 | C57BL/6JSmoc-Acly<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7623292 | C57BL/6JSmoc-Acly<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Acly/Acly
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Acly/Acly<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Publication
10794176 | -
First Author: Nowrousian M
Year: 2000
Journal: Curr Genet
Title: The fungal acl1 and acl2 genes encode two polypeptides with homology to the N- and C-terminal parts of the animal ATP citrate lyase polypeptide.
Volume: 37
Issue: 3
Pages: 189-93
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Publication
2295639 | -
First Author: Elshourbagy NA
Year: 1990
Journal: J Biol Chem
Title: Rat ATP citrate-lyase. Molecular cloning and sequence analysis of a full-length cDNA and mRNA abundance as a function of diet, organ, and age.
Volume: 265
Issue: 3
Pages: 1430-5
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Protein Domain
IPR014608 | ATP-citrate_synthase
Type: Family
Description: This entry represents eukaryotic ATP-citrate synthase (ACLY) (), also known as ATP citrate lyase. In bacteria and archaea, ATP citrate synthase is composed of two distinct subunits []. In eukaryotes, ATP citrate synthase is a homotetramer of a single large polypeptide, and is used to produce cytosolic acetyl-CoA from mitochondrial produced citrate [, , , ]. Acetyl-CoA is the building block for de novo lipid synthesis. As such, ACLY couples energy metabolism with fatty acids synthesis and plays a critical role in supporting cell growth [].
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HT Experiment
GSE252209 | RNA-seq analysis of Schwann cell knockout of ATP citrate lyase (ACLY)
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
37723306 | J:342227
First Author: Wartewig T
Year: 2023
Journal: Nat Cancer
Title: PD-1 instructs a tumor-suppressive metabolic program that restricts glycolysis and restrains AP-1 activity in T cell lymphoma.
Volume: 4
Issue: 10
Pages: 1508-1525
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Publication
9195992 | J:42796
First Author: Comincini S
Year: 1997
Journal: Mamm Genome
Title: Isolation of coding sequences from bovine cosmids by means of exon trapping.
Volume: 8
Issue: 7
Pages: 486-90
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Publication
33293558 | J:300980
First Author: Baardman J
Year: 2020
Journal: Nat Commun
Title: Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques.
Volume: 11
Issue: 1
Pages: 6296
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Publication
37689798 | J:340445
First Author: Fernandez-Fuente G
Year: 2023
Journal: Commun Biol
Title: The citrate transporters SLC13A5 and SLC25A1 elicit different metabolic responses and phenotypes in the mouse.
Volume: 6
Issue: 1
Pages: 926
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Publication
29787826 | J:341568
 
First Author: Wang M
Year: 2018
Journal: Gene
Title: Obesity-induced overexpression of miRNA-24 regulates cholesterol uptake and lipid metabolism by targeting SR-B1.
Volume: 668
Pages: 196-203
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Publication
28400497 | J:244823
 
First Author: Chu DT
Year: 2017
Journal: Physiol Rep
Title: C57BL/6J mice as a polygenic developmental model of diet-induced obesity.
Volume: 5
Issue: 7
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Publication
29929979 | J:267132
First Author: Chen LY
Year: 2018
Journal: J Biol Chem
Title: Modulation of matrix metabolism by ATP-citrate lyase in articular chondrocytes.
Volume: 293
Issue: 31
Pages: 12259-12270
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Publication
30150300 | J:270268
First Author: Shares BH
Year: 2018
Journal: J Biol Chem
Title: Active mitochondria support osteogenic differentiation by stimulating β-catenin acetylation.
Volume: 293
Issue: 41
Pages: 16019-16027
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Publication
31830561 | J:283656
 
First Author: Icard P
Year: 2020
Journal: Cancer Lett
Title: ATP citrate lyase: A central metabolic enzyme in cancer.
Volume: 471
Pages: 125-134
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Publication
23932781 | -
First Author: Lin R
Year: 2013
Journal: Mol Cell
Title: Acetylation stabilizes ATP-citrate lyase to promote lipid biosynthesis and tumor growth.
Volume: 51
Issue: 4
Pages: 506-518
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Publication
24818992 | J:217360
First Author: Shearn CT
Year: 2014
Journal: PLoS One
Title: Short term feeding of a high fat diet exerts an additive effect on hepatocellular damage and steatosis in liver-specific PTEN knockout mice.
Volume: 9
Issue: 5
Pages: e96553
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Publication
34974159 | J:321851
 
First Author: Zeng H
Year: 2022
Journal: Mol Metab
Title: CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processing.
Volume: 57
Pages: 101428
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Publication
36711926 | J:360843
     
First Author: Kobayashi T
Year: 2023
Journal: bioRxiv
Title: Reduced glycolysis links resting zone chondrocyte proliferation in the growth plate.
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Publication
17301242 | J:219098
First Author: Wiper-Bergeron N
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Glucocorticoid-stimulated preadipocyte differentiation is mediated through acetylation of C/EBPbeta by GCN5.
Volume: 104
Issue: 8
Pages: 2703-8
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Protein
E9Q1F7
Organism: Mus musculus/domesticus
Length: 211  
Fragment?: true
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Protein
F6ZCH1
Organism: Mus musculus/domesticus
Length: 66  
Fragment?: true
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Protein
F6SIC5
Organism: Mus musculus/domesticus
Length: 118  
Fragment?: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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