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Search results 501 to 600 out of 658 for Agt

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Hits by Pathway

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Hits by Strain

Type Details Score
Strain
MGI:3721536 | C.Cg-Enpp1<b>/Rbrc
Attribute String: congenic, mutant strain
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Publication
28559429 | J:244612
 
First Author: Lewis K
Year: 2017
Journal: Mol Cell Biol
Title: RNA Binding Protein CUGBP1 Inhibits Liver Cancer in a Phosphorylation-Dependent Manner.
Volume: 37
Issue: 16
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Publication
28535186 | J:245787
First Author: Valanejad L
Year: 2017
Journal: Carcinogenesis
Title: FXR-Gankyrin axis is involved in development of pediatric liver cancer.
Volume: 38
Issue: 7
Pages: 738-747
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Strain
MGI:6763026 | C57BL/6J-Ace2<em2Guru>/Mmjax
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7490021 | C57BL/6N-Sting1<em1Zjc>/J
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Tg(Fabp4-Agt)2Mte/?
Background: involves: C57BL/6 * CD-1 * DBA/2 * ICR
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Fabp4-Agt)1Mte/?
Background: involves: C57BL/6 * CD-1 * DBA/2 * ICR
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Col2a1/Col2a1
Background: involves: 129S6/SvEvTac * C57BL/6J * FVB/N
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Col2a1/Col2a1<+>
Background: involves: 129S6/SvEvTac * C57BL/6J * FVB/N
Zygosity: ht
Has Mutant Allele: true
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Publication
17634399 | J:145131
First Author: Kobori H
Year: 2007
Journal: Am J Physiol Renal Physiol
Title: Kidney-specific enhancement of ANG II stimulates endogenous intrarenal angiotensinogen in gene-targeted mice.
Volume: 293
Issue: 3
Pages: F938-45
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Publication
22248926 | J:184499
First Author: Lewis R
Year: 2012
Journal: Matrix Biol
Title: Disruption of the developmentally-regulated Col2a1 pre-mRNA alternative splicing switch in a transgenic knock-in mouse model.
Volume: 31
Issue: 3
Pages: 214-26
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Publication
35500653 | J:325540
First Author: Li Y
Year: 2022
Journal: J Biol Chem
Title: Phosphorylation at Ser724 of the ER stress sensor IRE1α governs its activation state and limits ER stress-induced hepatosteatosis.
Volume: 298
Issue: 6
Pages: 101997
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Publication
21239638 | J:168568
First Author: Tuomi JM
Year: 2011
Journal: Am J Physiol Heart Circ Physiol
Title: Atrial tachycardia/fibrillation in the connexin 43 G60S mutant (Oculodentodigital dysplasia) mouse.
Volume: 300
Issue: 4
Pages: H1402-11
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Allele
Tg(hAGT)2041Sig | MGI:2447399
Name: transgene insertion 2041, Curt Sigmund
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Hprt1<tm2(AGT)Sig> | MGI:2449453
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 2, Curt Sigmund
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Publication
29618634 | J:261783
 
First Author: Abitbol JM
Year: 2018
Journal: J Cell Sci
Title: Mice harbouring an oculodentodigital dysplasia-linked Cx43 G60S mutation have severe hearing loss.
Volume: 131
Issue: 9
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Publication
22752022 | J:315803
First Author: Lorentz R
Year: 2012
Journal: J Membr Biol
Title: Characterization of gap junction proteins in the bladder of Cx43 mutant mouse models of oculodentodigital dysplasia.
Volume: 245
Issue: 5-6
Pages: 345-55
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Publication
23075222 | J:194028
First Author: Stewart MK
Year: 2013
Journal: Biochem J
Title: The severity of mammary gland developmental defects is linked to the overall functional status of Cx43 as revealed by genetically modified mice.
Volume: 449
Issue: 2
Pages: 401-13
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Publication
24228978 | J:208385
First Author: Huang T
Year: 2014
Journal: Biochem J
Title: Myogenic bladder defects in mouse models of human oculodentodigital dysplasia.
Volume: 457
Issue: 3
Pages: 441-9
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Publication
32636381 | J:292197
First Author: Yamashiro LH
Year: 2020
Journal: Nat Commun
Title: Interferon-independent STING signaling promotes resistance to HSV-1 in vivo.
Volume: 11
Issue: 1
Pages: 3382
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Publication
22308025 | J:184573
First Author: Mascareno E
Year: 2012
Journal: J Biol Chem
Title: Cardiac lineage protein-1 (CLP-1) regulates cardiac remodeling via transcriptional modulation of diverse hypertrophic and fibrotic responses and angiotensin II-transforming growth factor β (TGF-β1) signaling axis.
Volume: 287
Issue: 16
Pages: 13084-93
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Allele
Per2<em1Vrshp> | MGI:6453858
Name: period circadian clock 2; endonuclease-mediated mutation 1, David Virshup
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Tg(Kap-REN)12403/1Sig | MGI:7788375
Name: transgene insertion 12403/1, Curt Sigmund
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Genotype
Genotype
Symbol: Csnk1d/Csnk1d<+> Tg(PER2*S662G)867Ljp/?
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Publication
12121276 | J:78186
First Author: Banakh I
Year: 2002
Journal: Eur J Immunogenet
Title: Structural basis of allotypes of ecto-nucleotide pyrophosphatase/phosphodiesterase (plasma cell membrane glycoprotein PC-1) in the mouse and rat, and analysis of allele-specific xenogeneic antibodies.
Volume: 29
Issue: 4
Pages: 307-13
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Publication
19429814 | J:151106
First Author: McKinnon RL
Year: 2009
Journal: Am J Physiol Heart Circ Physiol
Title: Reduction of electrical coupling between microvascular endothelial cells by NO depends on connexin37.
Volume: 297
Issue: 1
Pages: H93-H101
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Publication
17070838 | J:119658
First Author: Domenighetti AA
Year: 2007
Journal: J Mol Cell Cardiol
Title: Chronic angiotensin II stimulation in the heart produces an acquired long QT syndrome associated with IK1 potassium current downregulation.
Volume: 42
Issue: 1
Pages: 63-70
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Publication
9622149 | J:129140
First Author: Mazzolai L
Year: 1998
Journal: Hypertension
Title: Blood pressure-independent cardiac hypertrophy induced by locally activated renin-angiotensin system.
Volume: 31
Issue: 6
Pages: 1324-30
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Allele
Tg(Kap-icre)29066/2Sig | MGI:3806307
Name: transgene insertion 29066/2, Curt Sigmund
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Allele
Nfkbia<tm1.1Pjc> | MGI:4829878
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; targeted mutation 1.1, Paul J Chiao
Allele Type: Targeted
Attribute String: Modified regulatory region
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Genotype
Genotype
Symbol: Agt/Agt Tg(Fabp4-Agt)1Mte/?
Background: involves: C57BL/6 * CBA * DBA/2 * ICR
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Agt/Agt Tg(Fabp4-Agt)2Mte/?
Background: involves: C57BL/6 * CBA * DBA/2 * ICR
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hprt1/?
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hprt1/Hprt1
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hprt1/? Tg(REN)64071Sig/?
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hprt1/? Tg(REN)64071Sig/?
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CSNK1D,-EGFP)#Yfu/? Tg(PER2*S662G)867Ljp/?
Background: involves: C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Publication
27239044 | J:238164
First Author: Pagliarini R
Year: 2016
Journal: Cell Rep
Title: In Silico Modeling of Liver Metabolism in a Human Disease Reveals a Key Enzyme for Histidine and Histamine Homeostasis.
Volume: 15
Issue: 10
Pages: 2292-2300
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Publication
18597631 | J:155443
First Author: Plotkin LI
Year: 2008
Journal: J Bone Miner Res
Title: Connexin 43 is required for the anti-apoptotic effect of bisphosphonates on osteocytes and osteoblasts in vivo.
Volume: 23
Issue: 11
Pages: 1712-21
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Publication
22947655 | J:190459
First Author: Nieman BJ
Year: 2012
Journal: Physiol Genomics
Title: If the skull fits: magnetic resonance imaging and microcomputed tomography for combined analysis of brain and skull phenotypes in the mouse.
Volume: 44
Issue: 20
Pages: 992-1002
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Publication
35658715 | J:360400
First Author: Jia P
Year: 2022
Journal: Am J Physiol Renal Physiol
Title: Chemokine CCL2 from proximal tubular epithelial cells contributes to sepsis-induced acute kidney injury.
Volume: 323
Issue: 2
Pages: F107-F119
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Strain
MGI:2163288 | B6.Cg-Tg(hAGT)2041Sig/J
Attribute String: mutant strain, transgenic
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Publication
7798251 | J:79944
First Author: Yang G
Year: 1994
Journal: J Biol Chem
Title: Functional expression of the human angiotensinogen gene in transgenic mice.
Volume: 269
Issue: 51
Pages: 32497-502
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Publication
16636191 | J:128231
First Author: Brand M
Year: 2006
Journal: Hypertension
Title: Angiotensinogen modulates renal vasculature growth.
Volume: 47
Issue: 6
Pages: 1067-74
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Publication
24777977 | J:248601
First Author: Coble JP
Year: 2014
Journal: Hypertension
Title: Activity of protein kinase C-α within the subfornical organ is necessary for fluid intake in response to brain angiotensin.
Volume: 64
Issue: 1
Pages: 141-8
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Publication
21035755 | J:167912
First Author: Grobe JL
Year: 2010
Journal: Cell Metab
Title: The brain Renin-angiotensin system controls divergent efferent mechanisms to regulate fluid and energy balance.
Volume: 12
Issue: 5
Pages: 431-42
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Publication
11786522 | J:131098
First Author: Morimoto S
Year: 2002
Journal: Circ Res
Title: The brain renin-angiotensin system in transgenic mice carrying a highly regulated human renin transgene.
Volume: 90
Issue: 1
Pages: 80-6
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Publication
23535460 | J:197619
First Author: Littlejohn NK
Year: 2013
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Hypertension in mice with transgenic activation of the brain renin-angiotensin system is vasopressin dependent.
Volume: 304
Issue: 10
Pages: R818-28
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Publication
19318581 | J:147352
First Author: Vincent F
Year: 2009
Journal: Cancer Res
Title: Angiotensinogen delays angiogenesis and tumor growth of hepatocarcinoma in transgenic mice.
Volume: 69
Issue: 7
Pages: 2853-60
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Publication
31186446 | J:278660
First Author: Menikdiwela KR
Year: 2019
Journal: Sci Rep
Title: Angiotensin II Increases Endoplasmic Reticulum Stress in Adipose Tissue and Adipocytes.
Volume: 9
Issue: 1
Pages: 8481
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Publication
30874544 | J:293453
First Author: Peng X
Year: 2019
Journal: Cell Death Dis
Title: ATG5-mediated autophagy suppresses NF-κB signaling to limit epithelial inflammatory response to kidney injury.
Volume: 10
Issue: 4
Pages: 253
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Publication
37382161 | J:360959
First Author: Wu M
Year: 2023
Journal: Adv Sci (Weinh)
Title: TP53RK Drives the Progression of Chronic Kidney Disease by Phosphorylating Birc5.
Volume: 10
Issue: 25
Pages: e2301753
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Publication
25201884 | J:318630
First Author: Gall JM
Year: 2015
Journal: J Am Soc Nephrol
Title: Conditional knockout of proximal tubule mitofusin 2 accelerates recovery and improves survival after renal ischemia.
Volume: 26
Issue: 5
Pages: 1092-102
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Strain
MGI:3815459 | B6.Cg-Tg(Kap-icre)29066/2Sig/J
Attribute String: transgenic, congenic
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Publication
21753145 | J:178815
First Author: Li H
Year: 2011
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Renal proximal tubule angiotensin AT1A receptors regulate blood pressure.
Volume: 301
Issue: 4
Pages: R1067-77
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Publication
36629048 | J:339745
First Author: Bai M
Year: 2023
Journal: EMBO Mol Med
Title: LONP1 targets HMGCS2 to protect mitochondrial function and attenuate chronic kidney disease.
Volume: 15
Issue: 2
Pages: e16581
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Publication
39405939 | J:358459
First Author: Huang W
Year: 2024
Journal: Int Immunopharmacol
Title: Ulinastatin attenuates renal ischemia-reperfusion injury by inhibiting NLRP3 inflammasome-triggered pyroptosis.
Volume: 143
Issue: Pt 1
Pages: 113306
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Strain
MGI:7384864 | B6.129X1(Cg)-Nfkbia<tm1.1Pjc>/J
Attribute String: congenic, mutant strain, targeted mutation
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Publication
20696914 | J:163686
First Author: Peng B
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Defective feedback regulation of NF-kappaB underlies Sjogren's syndrome in mice with mutated kappaB enhancers of the IkappaBalpha promoter.
Volume: 107
Issue: 34
Pages: 15193-8
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Allele
Tg(Kap)L49Msgr | MGI:5792809
Name: transgene insertion L49, Anna Meseguer
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:6454052 | B6.129-Per2<em1Vrshp>/J
Attribute String: congenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Tg(hAGT)2041Sig/?
Background: involves: C57BL/6 * SJL/J
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Per2/Per2 Tg(PER2*S662G)867Ljp/?
Background: involves: C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nfkbia/Nfkbia
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Atg5/Atg5 Tg(Kap-icre)29066/2Sig/?
Background: involves: 129S/SvEv * C57BL/6J * SJL
Zygosity: cn
Has Mutant Allele: true
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Publication
23812390 | J:202269
First Author: Kawahito H
Year: 2013
Journal: Am J Physiol Heart Circ Physiol
Title: Periaortic adipose tissue-specific activation of the renin-angiotensin system contributes to atherosclerosis development in uninephrectomized apoE-/- mice.
Volume: 305
Issue: 5
Pages: H667-75
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Publication
37293374 | J:355511
 
First Author: Ye D
Year: 2023
Journal: Glob Transl Med
Title: Antisense oligonucleotides targeting hepatic angiotensinogen reduce atherosclerosis and liver steatosis in hypercholesterolemic mice.
Volume: 2
Issue: 1
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Publication
21385828 | J:173666
First Author: Wei W
Year: 2011
Journal: Carcinogenesis
Title: Targeted deletion of GSNOR in hepatocytes of mice causes nitrosative inactivation of O6-alkylguanine-DNA alkyltransferase and increased sensitivity to genotoxic diethylnitrosamine.
Volume: 32
Issue: 7
Pages: 973-7
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Publication
26536903 | J:237574
First Author: Ventura NM
Year: 2015
Journal: Biol Reprod
Title: Onset and Regression of Pregnancy-Induced Cardiac Alterations in Gestationally Hypertensive Mice: The Role of the Natriuretic Peptide System.
Volume: 93
Issue: 6
Pages: 142
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Publication
22205225 | J:182441
First Author: Lo CS
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Dual RAS blockade normalizes angiotensin-converting enzyme-2 expression and prevents hypertension and tubular apoptosis in Akita angiotensinogen-transgenic mice.
Volume: 302
Issue: 7
Pages: F840-52
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Publication
22664958 | J:208538
First Author: Lo CS
Year: 2012
Journal: Diabetes
Title: Heterogeneous nuclear ribonucleoprotein F suppresses angiotensinogen gene expression and attenuates hypertension and kidney injury in diabetic mice.
Volume: 61
Issue: 10
Pages: 2597-608
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Publication
29021226 | J:283138
First Author: Fitzgibbon WR
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Attenuation of accelerated renal cystogenesis in Pkd1 mice by renin-angiotensin system blockade.
Volume: 314
Issue: 2
Pages: F210-F218
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Publication
26391272 | J:237603
First Author: Saigusa T
Year: 2016
Journal: FASEB J
Title: Suppressing angiotensinogen synthesis attenuates kidney cyst formation in a Pkd1 mouse model.
Volume: 30
Issue: 1
Pages: 370-9
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Publication
26573705 | J:324478
First Author: Qin Q
Year: 2016
Journal: Hypertension
Title: Nrf2-Mediated Cardiac Maladaptive Remodeling and Dysfunction in a Setting of Autophagy Insufficiency.
Volume: 67
Issue: 1
Pages: 107-17
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Publication
31673025 | J:284239
First Author: Lo CS
Year: 2019
Journal: Sci Rep
Title: Tubular Deficiency of Heterogeneous Nuclear Ribonucleoprotein F Elevates Systolic Blood Pressure and Induces Glycosuria in Mice.
Volume: 9
Issue: 1
Pages: 15765
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Publication
23440427 | J:197058
First Author: Tang CH
Year: 2013
Journal: Cancer Res
Title: Hepatocarcinogenesis driven by GSNOR deficiency is prevented by iNOS inhibition.
Volume: 73
Issue: 9
Pages: 2897-904
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Publication
31055082 | J:278434
First Author: Wood KD
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Reduction in urinary oxalate excretion in mouse models of Primary Hyperoxaluria by RNA interference inhibition of liver lactate dehydrogenase activity.
Volume: 1865
Issue: 9
Pages: 2203-2209
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Publication
22589248 | J:185988
First Author: Thiele F
Year: 2012
Journal: Hum Mol Genet
Title: Cardiopulmonary dysfunction in the Osteogenesis imperfecta mouse model Aga2 and human patients are caused by bone-independent mechanisms.
Volume: 21
Issue: 16
Pages: 3535-45
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Publication
11536039 | J:71357
First Author: Reese JS
Year: 2001
Journal: Oncogene
Title: Overexpression of human O6-alkylguanine DNA alkyltransferase (AGT) prevents MNU induced lymphomas in heterozygous p53 deficient mice.
Volume: 20
Issue: 38
Pages: 5258-63
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Publication
1347476 | J:953
First Author: Richards-Smith BA
Year: 1992
Journal: Mamm Genome
Title: Mapping of the mouse ornithine decarboxylase-related sequence family.
Volume: 2
Issue: 4
Pages: 215-32
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Publication
8620508 | J:32570
First Author: Liu L
Year: 1996
Journal: Cancer Res
Title: Differential sensitivity of human and mouse alkyltransferase to O6-benzylguanine using a transgenic model.
Volume: 56
Issue: 8
Pages: 1880-5
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Publication
9197527 | J:40723
First Author: Furihata C
Year: 1997
Journal: Jpn J Cancer Res
Title: Rare occurrence of ras and p53 gene mutations in mouse stomach tumors induced by N-methyl-N-nitrosourea.
Volume: 88
Issue: 4
Pages: 363-8
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Publication
9403547 | J:45365
First Author: Smithies O
Year: 1997
Journal: Hypertension
Title: Theodore Cooper Memorial Lecture. A mouse view of hypertension.
Volume: 30
Issue: 6
Pages: 1318-24
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Publication
12006677 | J:77484
First Author: Morimoto S
Year: 2002
Journal: Physiol Genomics
Title: Neuron-specific expression of human angiotensinogen in brain causes increased salt appetite.
Volume: 9
Issue: 2
Pages: 113-20
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Publication
16126841 | J:107033
First Author: Hansen RJ
Year: 2005
Journal: J Pharmacol Exp Ther
Title: Role of O6-alkylguanine-DNA alkyltransferase in protecting against 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-induced long-term toxicities.
Volume: 315
Issue: 3
Pages: 1247-55
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Publication
17053195 | J:129086
First Author: Sinnayah P
Year: 2006
Journal: Circ Res
Title: Genetic ablation of angiotensinogen in the subfornical organ of the brain prevents the central angiotensinergic pressor response.
Volume: 99
Issue: 10
Pages: 1125-31
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Publication
11509454 | J:130420
First Author: Morimoto S
Year: 2001
Journal: Circ Res
Title: Elevated blood pressure in transgenic mice with brain-specific expression of human angiotensinogen driven by the glial fibrillary acidic protein promoter.
Volume: 89
Issue: 4
Pages: 365-72
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Publication
22613767 | J:188074
First Author: Rodríguez-Enfedaque A
Year: 2012
Journal: Biochim Biophys Acta
Title: zVAD-fmk upregulates caspase-9 cleavage and activity in etoposide-induced cell death of mouse embryonic fibroblasts.
Volume: 1823
Issue: 8
Pages: 1343-52
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Publication
31201268 | J:280388
First Author: Mopidevi B
Year: 2019
Journal: J Biol Chem
Title: A polymorphism in intron I of the human angiotensinogen gene (hAGT) affects binding by HNF3 and hAGT expression and increases blood pressure in mice.
Volume: 294
Issue: 31
Pages: 11829-11839
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Publication
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Strain
MGI:5569836 | B6.Cg-Gt(ROSA)26Sor<tm1Sor> Tg(Kap-icre)29066/2Sig
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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