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Search results 501 to 568 out of 568 for Akt3

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Type Details Score
Publication
19293429 | J:259097
First Author: Wang CY
Year: 2009
Journal: Sci Signal
Title: Obesity increases vascular senescence and susceptibility to ischemic injury through chronic activation of Akt and mTOR.
Volume: 2
Issue: 62
Pages: ra11
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Publication
19737566 | J:185258
First Author: Lin JE
Year: 2010
Journal: Gastroenterology
Title: The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling.
Volume: 138
Issue: 1
Pages: 241-54
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Publication
16904613 | J:112695
First Author: Phung TL
Year: 2006
Journal: Cancer Cell
Title: Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin.
Volume: 10
Issue: 2
Pages: 159-70
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Publication
20407209 | J:161466
First Author: Shimizu I
Year: 2010
Journal: J Clin Invest
Title: Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents.
Volume: 120
Issue: 5
Pages: 1506-14
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Publication
25266363 | J:253993
First Author: Chatterjee M
Year: 2014
Journal: Circ Res
Title: Macrophage migration inhibitory factor limits activation-induced apoptosis of platelets via CXCR7-dependent Akt signaling.
Volume: 115
Issue: 11
Pages: 939-49
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Publication
22824041 | J:188789
First Author: Yang KC
Year: 2012
Journal: J Mol Cell Cardiol
Title: Exercise training and PI3Kα-induced electrical remodeling is independent of cellular hypertrophy and Akt signaling.
Volume: 53
Issue: 4
Pages: 532-41
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Publication
28911943 | J:257166
 
First Author: Roy R
Year: 2017
Journal: J Mol Cell Cardiol
Title: Heterozygous deletion of AKT1 rescues cardiac contractility, but not hypertrophy, in a mouse model of Noonan Syndrome with Multiple Lentigines.
Volume: 112
Pages: 83-90
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Publication
24085786 | J:205053
First Author: Gibbons AV
Year: 2013
Journal: Cancer Res
Title: Intestinal GUCY2C prevents TGF-β secretion coordinating desmoplasia and hyperproliferation in colorectal cancer.
Volume: 73
Issue: 22
Pages: 6654-66
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Publication
24126057 | J:206064
First Author: Tsen F
Year: 2013
Journal: Mol Cell Biol
Title: Extracellular heat shock protein 90 signals through subdomain II and the NPVY motif of LRP-1 receptor to Akt1 and Akt2: a circuit essential for promoting skin cell migration in vitro and wound healing in vivo.
Volume: 33
Issue: 24
Pages: 4947-59
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Publication
33976210 | J:306337
First Author: Xing J
Year: 2021
Journal: Nat Commun
Title: Identification of poly(ADP-ribose) polymerase 9 (PARP9) as a noncanonical sensor for RNA virus in dendritic cells.
Volume: 12
Issue: 1
Pages: 2681
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Publication
22209699 | J:181962
First Author: Conley-LaComb MK
Year: 2012
Journal: Am J Pathol
Title: PTEN regulates PDGF ligand switch for β-PDGFR signaling in prostate cancer.
Volume: 180
Issue: 3
Pages: 1017-27
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Publication
12782654 | J:83741
First Author: Peng XD
Year: 2003
Journal: Genes Dev
Title: Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2.
Volume: 17
Issue: 11
Pages: 1352-65
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Publication
21507933 | J:173766
First Author: Endersby R
Year: 2011
Journal: Cancer Res
Title: Nonredundant functions for Akt isoforms in astrocyte growth and gliomagenesis in an orthotopic transplantation model.
Volume: 71
Issue: 12
Pages: 4106-16
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Publication
26709097 | J:295457
First Author: Xie X
Year: 2016
Journal: Obesity (Silver Spring)
Title: Tumor suppressor RIZ1 in obesity and the PI3K/AKT/mTOR pathway.
Volume: 24
Issue: 2
Pages: 389-97
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Publication
31138602 | J:279045
First Author: Kircher DA
Year: 2019
Journal: Mol Cancer Res
Title: AKT1E17K Activates Focal Adhesion Kinase and Promotes Melanoma Brain Metastasis.
Volume: 17
Issue: 9
Pages: 1787-1800
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Publication
16923802 | J:117197
First Author: Liu X
Year: 2006
Journal: J Biol Chem
Title: Quantitative analysis of anti-apoptotic function of Akt in Akt1 and Akt2 double knock-out mouse embryonic fibroblast cells under normal and stressed conditions.
Volume: 281
Issue: 42
Pages: 31380-8
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Publication
24942865 | J:216002
First Author: Jin Q
Year: 2014
Journal: Carcinogenesis
Title: Transcriptional and posttranslational regulation of insulin-like growth factor binding protein-3 by Akt3.
Volume: 35
Issue: 10
Pages: 2232-43
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Publication
26993778 | J:309336
First Author: Ji P
Year: 2016
Journal: Oncotarget
Title: Driver or passenger effects of augmented c-Myc and Cdc20 in gliomagenesis.
Volume: 7
Issue: 17
Pages: 23521-9
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Publication
33921698 | J:314111
 
First Author: Kwa MQ
Year: 2021
Journal: Cells
Title: MRCKα Is Dispensable for Breast Cancer Development in the MMTV-PyMT Model.
Volume: 10
Issue: 4
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Publication
30692211 | J:272998
First Author: Ouyang S
Year: 2019
Journal: J Immunol
Title: Akt-1 and Akt-2 Differentially Regulate the Development of Experimental Autoimmune Encephalomyelitis by Controlling Proliferation of Thymus-Derived Regulatory T Cells.
Volume: 202
Issue: 5
Pages: 1441-1452
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Publication
25240046 | J:216614
First Author: Babaev VR
Year: 2014
Journal: J Lipid Res
Title: Macrophage deficiency of Akt2 reduces atherosclerosis in Ldlr null mice.
Volume: 55
Issue: 11
Pages: 2296-308
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Publication
18218855 | J:133503
First Author: Li D
Year: 2008
Journal: Blood
Title: GSK3beta is a negative regulator of platelet function and thrombosis.
Volume: 111
Issue: 7
Pages: 3522-30
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Publication
30443181 | J:286948
First Author: Baek HJ
Year: 2018
Journal: Int J Biol Sci
Title: Inhibition of AKT suppresses the initiation and progression of BRCA1-associated mammary tumors.
Volume: 14
Issue: 13
Pages: 1769-1781
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Publication
14755341 | J:87588
First Author: Woulfe D
Year: 2004
Journal: J Clin Invest
Title: Defects in secretion, aggregation, and thrombus formation in platelets from mice lacking Akt2.
Volume: 113
Issue: 3
Pages: 441-50
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Publication
29378301 | J:321696
First Author: Ock S
Year: 2018
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Connexin43 and zonula occludens-1 are targets of Akt in cardiomyocytes that correlate with cardiac contractile dysfunction in Akt deficient hearts.
Volume: 1864
Issue: 4 Pt A
Pages: 1183-1191
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Publication
20705244 | J:163678
First Author: Lazorchak AS
Year: 2010
Journal: Mol Cell
Title: Sin1-mTORC2 suppresses rag and il7r gene expression through Akt2 in B cells.
Volume: 39
Issue: 3
Pages: 433-43
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Publication
25416384 | J:227793
First Author: Tang H
Year: 2015
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension.
Volume: 308
Issue: 2
Pages: L208-20
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Publication
18042802 | J:131334
First Author: Wofford JA
Year: 2008
Journal: Blood
Title: IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival.
Volume: 111
Issue: 4
Pages: 2101-11
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Publication
22678916 | J:187755
First Author: Chang X
Year: 2012
Journal: Eur J Immunol
Title: Sin1 regulates Treg-cell development but is not required for T-cell growth and proliferation.
Volume: 42
Issue: 6
Pages: 1639-47
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Publication
25136137 | J:216407
First Author: Lee MY
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates.
Volume: 111
Issue: 35
Pages: 12865-70
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Publication
26473496 | J:323790
First Author: Pauta M
Year: 2016
Journal: Hepatology
Title: Akt-mediated foxo1 inhibition is required for liver regeneration.
Volume: 63
Issue: 5
Pages: 1660-74
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Publication
22927331 | J:212626
First Author: Borst O
Year: 2012
Journal: Circ Res
Title: The inflammatory chemokine CXC motif ligand 16 triggers platelet activation and adhesion via CXC motif receptor 6-dependent phosphatidylinositide 3-kinase/Akt signaling.
Volume: 111
Issue: 10
Pages: 1297-307
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Publication
26654940 | J:302263
First Author: Franks SE
Year: 2016
Journal: Oncotarget
Title: Unique roles of Akt1 and Akt2 in IGF-IR mediated lung tumorigenesis.
Volume: 7
Issue: 3
Pages: 3297-316
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Publication
24056770 | J:202319
First Author: Canaud G
Year: 2013
Journal: Nat Med
Title: AKT2 is essential to maintain podocyte viability and function during chronic kidney disease.
Volume: 19
Issue: 10
Pages: 1288-96
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Publication
29133876 | J:257379
First Author: Protack CD
Year: 2017
Journal: Sci Rep
Title: Eph-B4 regulates adaptive venous remodeling to improve arteriovenous fistula patency.
Volume: 7
Issue: 1
Pages: 15386
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Publication
22384056 | J:185303
First Author: Lin JE
Year: 2012
Journal: PLoS One
Title: GUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT-dependent intestinal barrier integrity.
Volume: 7
Issue: 2
Pages: e31686
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Allele
Del(1Sdccag8-Akt3)CA1C2Ove | MGI:5306360
Name: deletion, Chr 1, Paul A Overbeek CA1C2
Allele Type: Transposon induced
Attribute String: Null/knockout
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Strain
MGI:5306373 | FVB/N-Del(1Sdccag8-Akt3)CA1C2Ove/J
Attribute String: mutant strain, transposition, coisogenic
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Genotype
Genotype
Symbol: Del(1Sdccag8-Akt3)CA1C2Ove/Del(1Sdccag8-Akt3)CA1C2Ove
Background: involves: FVB/N
Zygosity: hm
Has Mutant Allele: true
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Publication
35357006 | J:358032
First Author: Percival CJ
Year: 2022
Journal: J Anat
Title: The genetic basis of neurocranial size and shape across varied lab mouse populations.
Volume: 241
Issue: 2
Pages: 211-229
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Publication
25883023 | J:227240
First Author: Kofuji S
Year: 2015
Journal: Cancer Discov
Title: INPP4B Is a PtdIns(3,4,5)P3 Phosphatase That Can Act as a Tumor Suppressor.
Volume: 5
Issue: 7
Pages: 730-9
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Publication
23749633 | J:204828
First Author: Qiao G
Year: 2013
Journal: J Immunol
Title: T cell activation threshold regulated by E3 ubiquitin ligase Cbl-b determines fate of inducible regulatory T cells.
Volume: 191
Issue: 2
Pages: 632-9
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Publication
23345428 | J:194335
First Author: Yang ZF
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: GABP transcription factor is required for development of chronic myelogenous leukemia via its control of PRKD2.
Volume: 110
Issue: 6
Pages: 2312-7
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Publication
29025710 | J:269229
First Author: Jin Y
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Opposing Actions of AKT (Protein Kinase B) Isoforms in Vascular Smooth Muscle Injury and Therapeutic Response.
Volume: 37
Issue: 12
Pages: 2311-2321
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Publication
27238637 | J:256770
First Author: Titchenell PM
Year: 2016
Journal: Cell Metab
Title: Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production.
Volume: 23
Issue: 6
Pages: 1154-1166
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Publication
21633171 | J:175661
First Author: Espeillac C
Year: 2011
Journal: J Clin Invest
Title: S6 kinase 1 is required for rapamycin-sensitive liver proliferation after mouse hepatectomy.
Volume: 121
Issue: 7
Pages: 2821-32
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Publication
22344295 | J:181642
First Author: Lu M
Year: 2012
Journal: Nat Med
Title: Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1.
Volume: 18
Issue: 3
Pages: 388-95
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Publication
19500214 | J:150968
First Author: Jorgensen ND
Year: 2009
Journal: J Neurochem
Title: Phosphorylation of ATXN1 at Ser776 in the cerebellum.
Volume: 110
Issue: 2
Pages: 675-86
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Protein
Q8BZ47
Organism: Mus musculus/domesticus
Length: 1413  
Fragment?: false
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Protein
Q56A10
Organism: Mus musculus/domesticus
Length: 1511  
Fragment?: false
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Protein
B9EKR3
Organism: Mus musculus/domesticus
Length: 1511  
Fragment?: false
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Protein
B2RWS7
Organism: Mus musculus/domesticus
Length: 1363  
Fragment?: false
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Protein
Q8C6X4
Organism: Mus musculus/domesticus
Length: 198  
Fragment?: true
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Publication
29899041 | J:264617
First Author: Dharmat R
Year: 2018
Journal: J Cell Biol
Title: SPATA7 maintains a novel photoreceptor-specific zone in the distal connecting cilium.
Volume: 217
Issue: 8
Pages: 2851-2865
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Publication
22037765 | J:182721
First Author: Wan M
Year: 2012
Journal: Mol Cell Biol
Title: Loss of Akt1 in mice increases energy expenditure and protects against diet-induced obesity.
Volume: 32
Issue: 1
Pages: 96-106
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Publication
35581352 | J:326260
First Author: Di Pietro C
Year: 2022
Journal: Exp Mol Med
Title: Recruitment of monocytes primed to express heme oxygenase-1 ameliorates pathological lung inflammation in cystic fibrosis.
Volume: 54
Issue: 5
Pages: 639-652
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Publication
38367239 | J:350583
First Author: Gu X
Year: 2024
Journal: Cell Rep
Title: Macrophage-induced integrin signaling promotes Schlemm's canal formation to prevent intraocular hypertension and glaucomatous optic neuropathy.
Volume: 43
Issue: 2
Pages: 113799
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Publication
35878016 | J:336519
 
First Author: Simoes DCM
Year: 2022
Journal: J Cell Biol
Title: An integrin axis induces IFN-β production in plasmacytoid dendritic cells.
Volume: 221
Issue: 9
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Publication
25662011 | J:219885
First Author: Perry RJ
Year: 2015
Journal: Cell
Title: Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes.
Volume: 160
Issue: 4
Pages: 745-58
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Publication
17141631 | J:129773
First Author: Boxer RB
Year: 2006
Journal: Cell Metab
Title: Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation.
Volume: 4
Issue: 6
Pages: 475-90
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Publication
23919516 | J:317850
 
First Author: Watson KL
Year: 2013
Journal: BMC Cancer
Title: Loss of Akt1 or Akt2 delays mammary tumor onset and suppresses tumor growth rate in MTB-IGFIR transgenic mice.
Volume: 13
Pages: 375
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Publication
24126911 | J:204975
First Author: Rastogi R
Year: 2013
Journal: J Biol Chem
Title: Rapamycin induces mitogen-activated protein (MAP) kinase phosphatase-1 (MKP-1) expression through activation of protein kinase B and mitogen-activated protein kinase kinase pathways.
Volume: 288
Issue: 47
Pages: 33966-77
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Publication
29444170 | J:258011
First Author: Weihbrecht K
Year: 2018
Journal: PLoS One
Title: Genotypic and phenotypic characterization of the Sdccag8Tn(sb-Tyr)2161B.CA1C2Ove mouse model.
Volume: 13
Issue: 2
Pages: e0192755
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Publication
- | J:180503
     
First Author: Overbeek PA
Year: 2012
Journal: MGI Direct Data Submission
Title: Direct Data Submission 2012/02/16
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Publication
25730471 | J:220886
First Author: Jeffery E
Year: 2015
Journal: Nat Cell Biol
Title: Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity.
Volume: 17
Issue: 4
Pages: 376-85
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Publication
28486106 | J:242576
First Author: Zhang S
Year: 2017
Journal: Cancer Cell
Title: Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2.
Volume: 31
Issue: 5
Pages: 669-684.e7
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Publication
23028142 | J:188260
First Author: Chen CC
Year: 2012
Journal: Genes Dev
Title: Autocrine prolactin induced by the Pten-Akt pathway is required for lactation initiation and provides a direct link between the Akt and Stat5 pathways.
Volume: 26
Issue: 19
Pages: 2154-68
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Publication
21821099 | J:184660
 
First Author: Kvajo M
Year: 2012
Journal: Neuroscience
Title: Avoiding mouse traps in schizophrenia genetics: lessons and promises from current and emerging mouse models.
Volume: 211
Pages: 136-64
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