| Type |
Details |
Score |
| Gene Segment |
| Type: |
gene_segment |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Gene Segment |
| Type: |
gene_segment |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Gene Segment |
| Type: |
gene_segment |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Gene Segment |
| Type: |
gene_segment |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
116
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
108
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
104
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
117
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
104
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
187
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
209
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
120
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
451
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
595
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
101
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
116
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
116
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
99
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
113
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
98
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
120
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
120
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
116
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
100
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
119
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
120
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
119
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
118
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
117
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
100
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
119
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
116
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
98
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
115
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
105
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
119
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
116
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
119
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
117
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
120
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
119
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
117
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
119
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
120
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
120
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
131
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
119
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
106
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
100
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
116
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
118
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
120
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
99
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
120
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
117
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
119
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
117
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
114
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
117
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
119
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
117
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
116
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
119
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
99
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
117
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
120
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
119
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
120
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
146
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Allele |
| Name: |
ATPase, class VI, type 11C; mutation 1, Bruce Beutler |
| Allele Type: |
Chemically induced (ENU) |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
SH3-domain kinase binding protein 1; targeted mutation 1, Tomohiro Kurosaki |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
| Allele |
| Name: |
CD79A antigen (immunoglobulin-associated alpha); targeted mutation 1.1, Klaus Rajewsky |
| Allele Type: |
Targeted |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Nadine Hovelmeyer |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, Inserted expressed sequence, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
caspase recruitment domain family, member 11; endonuclease-mediated mutation 1, Wei Lu |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Humanized sequence |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Adachi T |
| Year: |
1998 |
| Journal: |
J Immunol |
| Title: |
The B cell surface protein CD72 recruits the tyrosine phosphatase SHP-1 upon tyrosine phosphorylation. |
| Volume: |
160 |
| Issue: |
10 |
| Pages: |
4662-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Infantino S |
| Year: |
2010 |
| Journal: |
J Exp Med |
| Title: |
Arginine methylation of the B cell antigen receptor promotes differentiation. |
| Volume: |
207 |
| Issue: |
4 |
| Pages: |
711-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Janssen E |
| Year: |
2003 |
| Journal: |
Nat Immunol |
| Title: |
LAB: a new membrane-associated adaptor molecule in B cell activation. |
| Volume: |
4 |
| Issue: |
2 |
| Pages: |
117-23 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chacko GW |
| Year: |
1996 |
| Journal: |
J Immunol |
| Title: |
Negative signaling in B lymphocytes induces tyrosine phosphorylation of the 145-kDa inositol polyphosphate 5-phosphatase, SHIP. |
| Volume: |
157 |
| Issue: |
6 |
| Pages: |
2234-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Walmsley MJ |
| Year: |
2003 |
| Journal: |
Science |
| Title: |
Critical roles for Rac1 and Rac2 GTPases in B cell development and signaling. |
| Volume: |
302 |
| Issue: |
5644 |
| Pages: |
459-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Srinivasan L |
| Year: |
2009 |
| Journal: |
Cell |
| Title: |
PI3 kinase signals BCR-dependent mature B cell survival. |
| Volume: |
139 |
| Issue: |
3 |
| Pages: |
573-86 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schuman J |
| Year: |
2009 |
| Journal: |
Blood |
| Title: |
A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation. |
| Volume: |
113 |
| Issue: |
19 |
| Pages: |
4566-74 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Llorian M |
| Year: |
2007 |
| Journal: |
J Immunol |
| Title: |
The PI3K p110delta is required for down-regulation of RAG expression in immature B cells. |
| Volume: |
178 |
| Issue: |
4 |
| Pages: |
1981-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Otipoby KL |
| Year: |
1996 |
| Journal: |
Nature |
| Title: |
CD22 regulates thymus-independent responses and the lifespan of B cells. |
| Volume: |
384 |
| Issue: |
6610 |
| Pages: |
634-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kraus M |
| Year: |
1999 |
| Journal: |
Immunity |
| Title: |
Ig-alpha cytoplasmic truncation renders immature B cells more sensitive to antigen contact. |
| Volume: |
11 |
| Issue: |
5 |
| Pages: |
537-45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Patterson HC |
| Year: |
2011 |
| Journal: |
J Immunol |
| Title: |
Cytoplasmic Ig alpha serine/threonines fine-tune Ig alpha tyrosine phosphorylation and limit bone marrow plasma cell formation. |
| Volume: |
187 |
| Issue: |
6 |
| Pages: |
2853-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pappu R |
| Year: |
1999 |
| Journal: |
Science |
| Title: |
Requirement for B cell linker protein (BLNK) in B cell development. |
| Volume: |
286 |
| Issue: |
5446 |
| Pages: |
1949-54 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wong S |
| Year: |
2001 |
| Journal: |
Oncogene |
| Title: |
Modeling Philadelphia chromosome positive leukemias. |
| Volume: |
20 |
| Issue: |
40 |
| Pages: |
5644-59 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ben-Neriah Y |
| Year: |
1986 |
| Journal: |
Cell |
| Title: |
Alternative 5' exons in c-abl mRNA. |
| Volume: |
44 |
| Issue: |
4 |
| Pages: |
577-86 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shinohara H |
| Year: |
2016 |
| Journal: |
FEBS Lett |
| Title: |
TAK1 adaptor proteins, TAB2 and TAB3, link the signalosome to B-cell receptor-induced IKK activation. |
| Volume: |
590 |
| Issue: |
18 |
| Pages: |
3264-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Behrens K |
| Year: |
2024 |
| Journal: |
Sci Adv |
| Title: |
ERG and c-MYC regulate a critical gene network in BCR::ABL1-driven B cell acute lymphoblastic leukemia. |
| Volume: |
10 |
| Issue: |
10 |
| Pages: |
eadj8803 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Qiao J |
| Year: |
2023 |
| Journal: |
Leukemia |
| Title: |
Targeting miR-126 in Ph+ acute lymphoblastic leukemia. |
| Volume: |
37 |
| Issue: |
7 |
| Pages: |
1540-1544 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhao X |
| Year: |
2002 |
| Journal: |
Nat Struct Biol |
| Title: |
Structure of the Bcr-Abl oncoprotein oligomerization domain. |
| Volume: |
9 |
| Issue: |
2 |
| Pages: |
117-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Laurent CE |
| Year: |
2004 |
| Journal: |
Exp Cell Res |
| Title: |
The c-Fes tyrosine kinase cooperates with the breakpoint cluster region protein (Bcr) to induce neurite extension in a Rac- and Cdc42-dependent manner. |
| Volume: |
299 |
| Issue: |
1 |
| Pages: |
188-98 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ochi H |
| Year: |
2000 |
| Journal: |
Int Immunol |
| Title: |
Negative regulation of B cell receptor-mediated signaling in B-1 cells through CD5 and Ly49 co-receptors via Lyn kinase activity. |
| Volume: |
12 |
| Issue: |
10 |
| Pages: |
1417-23 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xu Y |
| Year: |
2005 |
| Journal: |
Immunity |
| Title: |
Lyn tyrosine kinase: accentuating the positive and the negative. |
| Volume: |
22 |
| Issue: |
1 |
| Pages: |
9-18 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sampson M |
| Year: |
2007 |
| Journal: |
Front Biosci |
| Title: |
Src kinases in G-CSF receptor signaling. |
| Volume: |
12 |
|
| Pages: |
1463-74 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Waksman G |
| Year: |
2004 |
| Journal: |
Expert Rev Mol Med |
| Title: |
SH2 domains: role, structure and implications for molecular medicine. |
| Volume: |
6 |
| Issue: |
3 |
| Pages: |
1-18 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pawson T |
| Year: |
2001 |
| Journal: |
Trends Cell Biol |
| Title: |
SH2 domains, interaction modules and cellular wiring. |
| Volume: |
11 |
| Issue: |
12 |
| Pages: |
504-11 |
|
•
•
•
•
•
|