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Search results 501 to 600 out of 1045 for Brca2

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Type Details Score
Publication
32201259 | J:297226
First Author: Lu H
Year: 2020
Journal: Am J Pathol
Title: Spontaneous Development of Hepatocellular Carcinoma and B-Cell Lymphoma in Mosaic and Heterozygous Brca2 and Cdkn1a Interacting Protein Knockout Mice.
Volume: 190
Issue: 6
Pages: 1175-1187
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Publication
9192668 | J:41499
First Author: Mizuta R
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein.
Volume: 94
Issue: 13
Pages: 6927-32
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Publication
16869739 | J:116752
 
First Author: Tuveson DA
Year: 2005
Journal: Cold Spring Harb Symp Quant Biol
Title: Ductal pancreatic cancer in humans and mice.
Volume: 70
Pages: 65-72
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Publication
12930754 | J:85407
First Author: Percec I
Year: 2003
Journal: Genetics
Title: An N-ethyl-N-nitrosourea mutagenesis screen for epigenetic mutations in the mouse.
Volume: 164
Issue: 4
Pages: 1481-94
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Publication
16951165 | J:113389
First Author: Hulit J
Year: 2006
Journal: Cancer Res
Title: p27Kip1 repression of ErbB2-induced mammary tumor growth in transgenic mice involves Skp2 and Wnt/beta-catenin signaling.
Volume: 66
Issue: 17
Pages: 8529-41
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Publication
28608929 | J:247957
First Author: Zhai Y
Year: 2017
Journal: J Pathol
Title: High-grade serous carcinomas arise in the mouse oviduct via defects linked to the human disease.
Volume: 243
Issue: 1
Pages: 16-25
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Publication
16139793 | J:101000
First Author: Sakuraba Y
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Molecular characterization of ENU mouse mutagenesis and archives.
Volume: 336
Issue: 2
Pages: 609-16
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UniProt Feature
UniProt Feature
Begin: 1
Description: BRCA2 and CDKN1A-interacting protein
Type: chain
End: 316
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Publication
34267330 | J:309380
First Author: Mei L
Year: 2021
Journal: Oncogene
Title: SUMOylation activates large tumour suppressor 1 to maintain the tissue homeostasis during Hippo signalling.
Volume: 40
Issue: 35
Pages: 5357-5366
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Publication
32845237 | J:303558
   
First Author: Felipe-Medina N
Year: 2020
Journal: Elife
Title: A missense in HSF2BP causing primary ovarian insufficiency affects meiotic recombination by its novel interactor C19ORF57/BRME1.
Volume: 9
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Publication
19076778 | J:173443
First Author: Huse JT
Year: 2009
Journal: Brain Pathol
Title: Genetically engineered mouse models of brain cancer and the promise of preclinical testing.
Volume: 19
Issue: 1
Pages: 132-43
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Publication
9917000 | J:52202
First Author: Ghebranious N
Year: 1998
Journal: Oncogene
Title: Mouse models in tumor suppression.
Volume: 17
Issue: 25
Pages: 3385-400
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Publication
26178733 | J:316183
 
First Author: Cai Y
Year: 2015
Journal: BMC Pulm Med
Title: Transgenically-expressed secretoglobin 3A2 accelerates resolution of bleomycin-induced pulmonary fibrosis in mice.
Volume: 15
Pages: 72
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Publication
27739607 | J:301847
First Author: Ni L
Year: 2016
Journal: Mol Reprod Dev
Title: Multiple roles of FOXJ3 in spermatogenesis: A lesson from Foxj3 conditional knockout mouse models.
Volume: 83
Issue: 12
Pages: 1060-1069
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Publication
32737294 | J:331939
First Author: Keil JM
Year: 2020
Journal: Nat Commun
Title: Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80.
Volume: 11
Issue: 1
Pages: 3839
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Publication
30538199 | J:269212
First Author: Dumitrache LC
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Apurinic endonuclease-1 preserves neural genome integrity to maintain homeostasis and thermoregulation and prevent brain tumors.
Volume: 115
Issue: 52
Pages: E12285-E12294
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Publication
30709655 | J:278287
First Author: Tang T
Year: 2019
Journal: Neuron
Title: HDAC1 and HDAC2 Regulate Intermediate Progenitor Positioning to Safeguard Neocortical Development.
Volume: 101
Issue: 6
Pages: 1117-1133.e5
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Publication
37269288 | J:337931
First Author: Li L
Year: 2023
Journal: Cell Rep
Title: Mettl14-mediated m(6)A modification ensures the cell-cycle progression of late-born retinal progenitor cells.
Volume: 42
Issue: 6
Pages: 112596
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
34746147 | J:314268
 
First Author: Akagawa R
Year: 2021
Journal: Front Cell Dev Biol
Title: Alternative Functions of Cell Cycle-Related and DNA Repair Proteins in Post-mitotic Neurons.
Volume: 9
Pages: 753175
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
22560297 | J:184521
First Author: Koss M
Year: 2012
Journal: Dev Cell
Title: Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.
Volume: 22
Issue: 5
Pages: 913-26
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:104881
     
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
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Publication
21731673 | J:174767
First Author: Tang F
Year: 2011
Journal: PLoS One
Title: Deterministic and stochastic allele specific gene expression in single mouse blastomeres.
Volume: 6
Issue: 6
Pages: e21208
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Publication
- | J:46439
     
First Author: Freeman TC
Year: 1998
Journal: MGI Direct Data Submission
Title: Expression Mapping of Mouse Genes
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Gene
361666 | Bccip
Type: gene
Organism: rat
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Gene
293452 | Palb2
Type: gene
Organism: rat
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Gene
477864 | BCCIP
Type: gene
Organism: dog, domestic
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Gene
608527 | PALB2
Type: gene
Organism: dog, domestic
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Gene
453988 | PALB2
Type: gene
Organism: chimpanzee
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Gene
738638 | BCCIP
Type: gene
Organism: chimpanzee
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Gene
361607 | Emsy
Type: gene
Organism: rat
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Gene
466716 | EMSY
Type: gene
Organism: chimpanzee
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Gene
476800 | EMSY
Type: gene
Organism: dog, domestic
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Gene
507620 | PALB2
Type: gene
Organism: cattle
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Gene
512466 | BCCIP
Type: gene
Organism: cattle
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Gene
540919 | EMSY
Type: gene
Organism: cattle
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Gene
416572 | PALB2
Type: gene
Organism: chicken
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Gene
419090 | EMSY
Type: gene
Organism: chicken
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Gene
426225 | BCCIP
Type: gene
Organism: chicken
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Gene
335889 | emsy
Type: gene
Organism: zebrafish
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Gene
541348 | bccip
Type: gene
Organism: zebrafish
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Gene
558923 | palb2
Type: gene
Organism: zebrafish
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Gene
697319 | EMSY
Type: gene
Organism: macaque, rhesus
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Gene
699437 | BCCIP
Type: gene
Organism: macaque, rhesus
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Gene
700843 | PALB2
Type: gene
Organism: macaque, rhesus
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Gene
718070 | LOC718070
Type: gene
Organism: macaque, rhesus
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Gene
101885447 | cntrob
Type: gene
Organism: zebrafish
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Gene
100491433 | palb2
Type: gene
Organism: frog, western clawed
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Gene
448392 | bccip
Type: gene
Organism: frog, western clawed
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Protein Domain
IPR036315 | BRCA2_hlx_sf
Type: Homologous_superfamily
Description: This entry represents a domain found in BRCA2 proteins. This domain adopts a helical structure, consisting of a four-helix cluster core (alpha 1, alpha 8, alpha 9, alpha 10) and two successive β-hairpins (beta 1 to beta 4). An approximately 50-amino acid segment that contains four short helices (alpha 2 to alpha 4), meanders around the surface of the core structure. In BRCA2, thealpha 9 and alpha 10 helices pack with BRCA-2_OB1 () through van der Waals contacts involving hydrophobic and aromatic residues, and also through side-chain and backbone hydrogen bonds. This domain binds the 70-amino acid DSS1 (deleted in split-hand/split foot syndrome) protein, which was originally identified as one of three genes that map to a 1.5-Mb locus deleted in an inherited developmental malformation syndrome [].
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Protein Coding Gene
MGI:2443290 | Cntrob
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1913415 | Bccip
Type: protein_coding_gene
Organism: mouse, laboratory
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UniProt Feature
UniProt Feature
Begin: 1
Description: Partner and localizer of BRCA2
Type: chain
End: 1104
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Allele
Brca2<tm2Mak> | MGI:2429691
Name: breast cancer 2, early onset; targeted mutation 2, Tak W Mak
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Publication
19369211 | -
First Author: Sy SM
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: PALB2 is an integral component of the BRCA complex required for homologous recombination repair.
Volume: 106
Issue: 17
Pages: 7155-60
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Publication
30638972 | -
First Author: Ducy M
Year: 2019
Journal: Trends Biochem Sci
Title: The Tumor Suppressor PALB2: Inside Out.
Volume: 44
Issue: 3
Pages: 226-240
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Protein Domain
IPR042417 | PALB2
Type: Family
Description: PALB2 (partner and Localizer of BRCA2) binds to the N-terminal region of BRCA2, and is vital for its function by facilitating its subnuclear localization []. It binds BRCA1 and BRCA2 and serves as the molecular scaffold in the formation of the BRCA1-PALB2-BRCA2 complex, which is required for homologous recombination repair []. It has also been shown to bind DNA and physically interacts with RAD51 []. Biallelic mutations in PALB2 cause Fanconi anemia (FA) subtype FA-N, whereas monoallelic mutations predispose to breast, and pancreatic familial cancers[].
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Publication
10652564 | J:60831
First Author: Ingvarsson S
Year: 1999
Journal: Anticancer Res
Title: The Brca1 and Brca2 proteins and tumor pathogenesis.
Volume: 19
Issue: 4B
Pages: 2853-61
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Protein
A0A3T0ZJB3
Organism: Mus musculus/domesticus
Length: 338  
Fragment?: false
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Allele
Brca2<tm1Mbn> | MGI:2387337
Name: breast cancer 2, early onset; targeted mutation 1, L Michelle Bennett
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
26748828 | J:231093
First Author: Zimmer J
Year: 2016
Journal: Mol Cell
Title: Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds.
Volume: 61
Issue: 3
Pages: 449-460
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Gene
108697395 | bccip.S
Type: gene
Organism: frog, African clawed
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Gene
108703181 | palb2.S
Type: gene
Organism: frog, African clawed
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Gene
444344 | bccip.L
Type: gene
Organism: frog, African clawed
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Gene
733293 | palb2.L
Type: gene
Organism: frog, African clawed
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Protein
Q3U0P1-3
Organism: Mus musculus/domesticus
Length: 384  
Fragment?: false
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Protein
Q3U0P1-2
Organism: Mus musculus/domesticus
Length: 741  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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