| Type |
Details |
Score |
| Publication |
| First Author: |
Miura N |
| Year: |
1993 |
| Journal: |
FEBS Lett |
| Title: |
MFH-1, a new member of the fork head domain family, is expressed in developing mesenchyme. |
| Volume: |
326 |
| Issue: |
1-3 |
| Pages: |
171-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bin NR |
| Year: |
2018 |
| Journal: |
J Immunol |
| Title: |
C2 Domains of Munc13-4 Are Crucial for Ca2+-Dependent Degranulation and Cytotoxicity in NK Cells. |
| Volume: |
201 |
| Issue: |
2 |
| Pages: |
700-713 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
inbred strain |
|
•
•
•
•
•
|
| MP Term |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Farah CA |
| Year: |
2012 |
| Journal: |
Adv Exp Med Biol |
| Title: |
The role of C2 domains in PKC signaling. |
| Volume: |
740 |
|
| Pages: |
663-83 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1658
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kuroda TS |
| Year: |
2002 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Synaptotagmin-like protein 5: a novel Rab27A effector with C-terminal tandem C2 domains. |
| Volume: |
293 |
| Issue: |
3 |
| Pages: |
899-906 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
753
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| GO Term |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Friedland N |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Structure of a cholesterol-binding protein deficient in Niemann-Pick type C2 disease. |
| Volume: |
100 |
| Issue: |
5 |
| Pages: |
2512-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pena V |
| Year: |
2008 |
| Journal: |
EMBO Rep |
| Title: |
The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction. |
| Volume: |
9 |
| Issue: |
4 |
| Pages: |
350-5 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
470
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kojima T |
| Year: |
1996 |
| Journal: |
J Biochem |
| Title: |
Calcium-dependent phospholipid binding to the C2A domain of a ubiquitous form of double C2 protein (Doc2 beta). |
| Volume: |
120 |
| Issue: |
3 |
| Pages: |
671-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Inoue A |
| Year: |
2001 |
| Journal: |
Eur J Biochem |
| Title: |
S1 proteins C2 and D2 are novel hnRNPs similar to the transcriptional repressor, CArG box motif-binding factor A. |
| Volume: |
268 |
| Issue: |
13 |
| Pages: |
3654-63 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1071
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Creutz CE |
| Year: |
1998 |
| Journal: |
J Biol Chem |
| Title: |
The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from Paramecium to humans. |
| Volume: |
273 |
| Issue: |
3 |
| Pages: |
1393-402 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
706
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
294
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Srivastava S |
| Year: |
2017 |
| Journal: |
PLoS One |
| Title: |
Phosphatidlyinositol-3-kinase C2 beta (PI3KC2β) is a potential new target to treat IgE mediated disease. |
| Volume: |
12 |
| Issue: |
8 |
| Pages: |
e0183474 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Robinson CJ |
| Year: |
2024 |
| Journal: |
Am J Pathol |
| Title: |
Release of miR-29 Target Laminin C2 Improves Skin Repair. |
| Volume: |
194 |
| Issue: |
2 |
| Pages: |
195-208 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Harrison KD |
| Year: |
2009 |
| Journal: |
Cell Metab |
| Title: |
Nogo-B receptor stabilizes Niemann-Pick type C2 protein and regulates intracellular cholesterol trafficking. |
| Volume: |
10 |
| Issue: |
3 |
| Pages: |
208-18 |
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
1 |
| Description: |
Cold shock domain-containing protein C2 |
| Type: |
chain |
| End: |
154 |
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
1 |
| Description: |
C2 calcium-dependent domain-containing protein 4C |
| Type: |
chain |
| End: |
419 |
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
1 |
| Description: |
EF-hand domain-containing family member C2 |
| Type: |
chain |
| End: |
750 |
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
1 |
| Description: |
C2 calcium-dependent domain-containing protein 4D |
| Type: |
chain |
| End: |
341 |
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
1 |
| Description: |
Tandem C2 domains nuclear protein |
| Type: |
chain |
| End: |
489 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
462
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Leach RE |
| Year: |
2002 |
| Journal: |
Mamm Genome |
| Title: |
Identification, molecular characterization, and tissue expression of OVCOV1. |
| Volume: |
13 |
| Issue: |
11 |
| Pages: |
619-24 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ogata S |
| Year: |
2012 |
| Journal: |
PLoS One |
| Title: |
A novel function of Noc2 in agonist-induced intracellular Ca2+ increase during zymogen-granule exocytosis in pancreatic acinar cells. |
| Volume: |
7 |
| Issue: |
5 |
| Pages: |
e37048 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Corbalan-Garcia S |
| Year: |
2014 |
| Journal: |
Biochim Biophys Acta |
| Title: |
Signaling through C2 domains: more than one lipid target. |
| Volume: |
1838 |
| Issue: |
6 |
| Pages: |
1536-47 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
The C2 domain is a Ca2+-dependent membrane-targeting module found in many cellular proteins involved in signal transduction or membrane trafficking. C2 domains are unique among membrane targeting domains in that they show wide range of lipid selectivity for the major components of cell membranes, including phosphatidylserine and phosphatidylcholine. This C2 domain is about 116 amino-acid residues and is located between the two copies of the C1 domain in Protein Kinase C and the protein kinase catalytic domain []. Regions with significant homology []to the C2-domain have been found in many proteins. The C2 domain is thought to be involved in calcium-dependent phospholipid binding []and in membrane targetting processes such as subcellular localisation. The 3D structure of the C2 domain of synaptotagmin has been reported[], the domain forms an eight-stranded β-sandwich constructed around a conserved 4-stranded motif, designated a C2 key []. Calcium binds in a cup-shaped depression formed by the N- and C-terminal loops of the C2-key motif. Structural analyses of several C2 domains have shown them to consist of similar ternary structures in which three Ca2+-binding loops are located at the end of an 8 stranded antiparallel β-sandwich. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Botto M |
| Year: |
2009 |
| Journal: |
Mol Immunol |
| Title: |
Complement in human diseases: Lessons from complement deficiencies. |
| Volume: |
46 |
| Issue: |
14 |
| Pages: |
2774-83 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Truedsson L |
| Year: |
2015 |
| Journal: |
Mol Immunol |
| Title: |
Classical pathway deficiencies - A short analytical review. |
| Volume: |
68 |
| Issue: |
1 |
| Pages: |
14-9 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
This entry represents complement component C2, a component of the classical and lectin activation pathway of complement. C2 is cleaved by C1s (classical) or mannan-binding lectin-associated serine peptidases (lectin) into C2a and C2b []. C2a is a serine endopeptidase from family S1 (chymotrypsin family; MEROPS identifier S01.194) which complexes with C4b to form the C3/C5 convertase []. The complex is stabilized by Mg2+[, ]. The C3/C5 convertase has trypsin-like specificity []. C2 deficiency is the commonest human complement deficiency, which can result in systemic lupus erythematosus-like immune complex diseases []. The C2 gene is part of the major histocompatabaility complex []. |
|
•
•
•
•
•
|
| EMAPA Term |
| Starts At: |
26 |
| Ends At: |
26 |
|
•
•
•
•
•
|
| EMAPA Term |
| Starts At: |
26 |
| Ends At: |
26 |
|
•
•
•
•
•
|
| EMAPA Term |
| Starts At: |
15 |
| Ends At: |
16 |
|
•
•
•
•
•
|
| EMAPA Term |
| Starts At: |
22 |
| Ends At: |
26 |
|
•
•
•
•
•
|
| EMAPA Term |
| Starts At: |
26 |
| Ends At: |
26 |
|
•
•
•
•
•
|
| EMAPA Term |
| Starts At: |
26 |
| Ends At: |
26 |
|
•
•
•
•
•
|
| EMAPA Term |
| Starts At: |
15 |
| Ends At: |
28 |
|
•
•
•
•
•
|
| EMAPA Term |
| Starts At: |
22 |
| Ends At: |
26 |
|
•
•
•
•
•
|
| EMAPA Term |
| Starts At: |
26 |
| Ends At: |
26 |
|
•
•
•
•
•
|
| EMAPA Term |
| Starts At: |
26 |
| Ends At: |
26 |
|
•
•
•
•
•
|
| EMAPA Term |
| Starts At: |
26 |
| Ends At: |
28 |
|
•
•
•
•
•
|
| EMAPA Term |
| Starts At: |
26 |
| Ends At: |
26 |
|
•
•
•
•
•
|
| EMAPA Term |
| Starts At: |
22 |
| Ends At: |
26 |
|
•
•
•
•
•
|
| EMAPA Term |
| Starts At: |
26 |
| Ends At: |
26 |
|
•
•
•
•
•
|
| EMAPA Term |
| Starts At: |
17 |
| Ends At: |
21 |
|
•
•
•
•
•
|
| EMAPA Term |
| Starts At: |
26 |
| Ends At: |
26 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1694238 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1942023 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4823527 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_001233_13 |
|
| Specimen Label: |
euxassay_001233_13 |
| Detected: |
true |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1739417 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1942023 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4823768 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_001234_13 |
|
| Specimen Label: |
euxassay_001234_13 |
| Detected: |
true |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1739417 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1942123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4823768 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_001234_14 |
|
| Specimen Label: |
euxassay_001234_14 |
| Detected: |
true |
| Specimen Num: |
14 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1341313 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
1999-08-10 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933620 |
|
| Stage: |
TS20 |
| Assay Id: |
MGI:1341315 |
| Age: |
embryonic day 12.5 |
| Image: |
6B |
|
| Specimen Label: |
6B |
| Detected: |
false |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927926 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933619 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:1928653 |
| Age: |
embryonic day 11.5 |
| Image: |
8. A., B. |
| Note: |
Expression is detected in the paraxial mesoderm up to and in the most caudal region of basioccipital bone anlage. Expression is also detected in the vertebrae from thoracic 11 up to cervical 1. Data posterior to C5 is summarized in Fig. 9. |
| Specimen Label: |
8. A., B. |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927926 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933619 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:1928653 |
| Age: |
embryonic day 11.5 |
| Image: |
8. C., D. |
| Note: |
Expression is detected in the paraxial mesoderm up to cervical vertebrae 1. Expression is also detected in the vertebrae from thoracic 11 up to cervical 1. Data posterior to C5 is summarized in Fig. 9. |
| Specimen Label: |
8. C., D. |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927928 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933619 |
| Pattern: |
Uniform |
| Stage: |
TS19 |
| Assay Id: |
MGI:1928656 |
| Age: |
embryonic day 11.5 |
| Image: |
8. E., F. |
| Note: |
Expression is detected in the vertebrae from thoracic 11 up to cervical 1. Data posterior to C5 is summarized in Fig. 9. |
| Specimen Label: |
8. E., F. |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927928 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933619 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:1928656 |
| Age: |
embryonic day 11.5 |
| Image: |
8. G., H. |
| Note: |
Expression is detected in the vertebrae from thoracic 11 up to the boundary between vertebrae 1 and 2. Data posterior to C5 is summarized in Fig. 9. |
| Specimen Label: |
8. G., H. |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927972 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933619 |
| Pattern: |
Uniform |
| Stage: |
TS19 |
| Assay Id: |
MGI:1928657 |
| Age: |
embryonic day 11.5 |
| Image: |
8. I., J. |
| Note: |
Expression is detected in the vertebrae from thoracic 11 up to cervical 1. Data posterior to C5 is summarized in Fig. 9. |
| Specimen Label: |
8. I., J. |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927972 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933619 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:1928657 |
| Age: |
embryonic day 11.5 |
| Image: |
8. K., L. |
| Note: |
Expression is detected in the vertebrae from thoracic 11 up to the boundary between vertebrae 1 and 2. Data posterior to C5 is summarized in Fig. 9. |
| Specimen Label: |
8. K., L. |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927951 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933619 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:1928658 |
| Age: |
embryonic day 11.5 |
| Image: |
8. M., N. |
| Note: |
Expression is detected in the vertebrae from thoracic 11 up to the boundary between cervical vertebrae 1 and 2. Data posterior to C5 is summarized in Fig. 9. |
| Specimen Label: |
8. M., N. |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927951 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933619 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:1928658 |
| Age: |
embryonic day 11.5 |
| Image: |
8. O., P. |
| Note: |
Expression is detected in the vertebrae from thoracic 11 up to the boundary between cervical vertebrae 1 and 2 for 2 of 4 specimens. The boundary is between C2/3 for two other specimens. Data posterior to C5 is summarized in Fig. 9. |
| Specimen Label: |
8. O., P. |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927918 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933619 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:1928659 |
| Age: |
embryonic day 11.5 |
|
| Note: |
Expression is detected in the vertebrae from thoracic 11 up to the boundary between cervical vertebrae 1 and 2. Data is summarized in Fig. 9. |
| Specimen Label: |
E11.5 -/- |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927921 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933619 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:1928660 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
E11.5 -/- |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927921 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933619 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:1928660 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
E11.5 +/+ |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927953 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933619 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:1928661 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
E11.5 -/- |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927953 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933619 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:1928661 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
E11.5 +/+ |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927964 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933619 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:1928662 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
E11.5 -/- |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927964 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933619 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:1928662 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
E11.5 +/+ |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927966 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933619 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:1928663 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
E11.5 -/- |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927966 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933619 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:1928663 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
E11.5 +/+ |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927968 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933619 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:1928664 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
E11.5 -/- |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927968 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933619 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:1928664 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
E11.5 +/+ |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933619 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:1928665 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
E11.5 -/- |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927977 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933620 |
| Pattern: |
Uniform |
| Stage: |
TS20 |
| Assay Id: |
MGI:1928652 |
| Age: |
embryonic day 12.5 |
| Image: |
7. A., B. |
| Note: |
Cartilage condensations in the anterior arch of the atlas are not visible suggesting a loss of identity of C1. However, expression is detected up to and including the level of the proatlas. |
| Specimen Label: |
7. A., B. |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927977 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933620 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:1928652 |
| Age: |
embryonic day 12.5 |
| Image: |
7. C., D. |
|
| Specimen Label: |
7. C., D. |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933619 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:1928665 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
E11.5 +/+ |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1927918 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-01-09 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933619 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:1928659 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
E11.5 +/+ |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1932921 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-05-21 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933620 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:1934225 |
| Age: |
embryonic day 12.5 |
| Image: |
3A |
|
| Specimen Label: |
3A |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1932922 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-05-21 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933620 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:1934226 |
| Age: |
embryonic day 12.5 |
| Image: |
3 B |
|
| Specimen Label: |
3 B |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1932893 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2001-05-21 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933620 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:1934227 |
| Age: |
embryonic day 12.5 |
| Image: |
3 C |
|
| Specimen Label: |
3 C |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1342074 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
1999-08-18 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933620 |
|
| Stage: |
TS20 |
| Assay Id: |
MGI:1342087 |
| Age: |
embryonic day 12.5 |
| Image: |
6B -4.3 |
| Note: |
The Hox-4.3 expression domain is restricted along the anteroposterior axis in some ectoderm (the nervous system) and mesoderm derivatives (e.g. the prevertebrae, gut, or kidney). |
| Specimen Label: |
6B -4.3 |
| Detected: |
false |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1339019 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2003-01-08 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933620 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:2447476 |
| Age: |
embryonic day 12.5 |
| Image: |
12C |
| Note: |
Labelling begins to weaken at the second thoracic prevertebra but remains slightly above background until the most posterior identified prevertebra. |
| Specimen Label: |
12C |
| Detected: |
true |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1932893 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2009-05-12 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933620 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:3843877 |
| Age: |
embryonic day 12.5 |
| Image: |
6b |
| Note: |
Expression in the prevertebra, including that of the axis. |
| Specimen Label: |
6b |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3798091 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2017-01-24 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933620 |
|
| Stage: |
TS20 |
| Assay Id: |
MGI:5818864 |
| Age: |
embryonic day 12.5 |
| Image: |
6 |
|
| Specimen Label: |
6 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5818903 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2017-01-24 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933620 |
|
| Stage: |
TS20 |
| Assay Id: |
MGI:5818904 |
| Age: |
embryonic day 12.5 |
|
|
| Specimen Label: |
not shown |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6189538 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-24 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933620 |
| Pattern: |
Regionally restricted |
| Stage: |
TS20 |
| Assay Id: |
MGI:6189543 |
| Age: |
embryonic day 12.5 |
| Image: |
1G |
| Note: |
Expression in (C1) atlas and (C2) axis prevertebra. Expression in sclerotomal cells from fifth somite contributing to both prevertebra. |
| Specimen Label: |
1G |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6195620 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-01-17 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933620 |
| Pattern: |
Regionally restricted |
| Stage: |
TS20 |
| Assay Id: |
MGI:6273776 |
| Age: |
embryonic day 12.5 |
| Image: |
4B |
| Note: |
Expression in prospective vertebral bodies of cervical vertebra C1 through C6. |
| Specimen Label: |
4B |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6195620 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-01-17 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933620 |
| Pattern: |
Regionally restricted |
| Stage: |
TS20 |
| Assay Id: |
MGI:6273776 |
| Age: |
embryonic day 12.5 |
| Image: |
4D |
| Note: |
Authors state expression is similar to that of wild-type embryos. |
| Specimen Label: |
4D |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6195620 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-01-17 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933620 |
| Pattern: |
Regionally restricted |
| Stage: |
TS20 |
| Assay Id: |
MGI:6273776 |
| Age: |
embryonic day 12.5 |
| Image: |
S2E/G |
| Note: |
Expression in prospective vertebral bodies. |
| Specimen Label: |
S2E/G |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6195620 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-01-17 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933620 |
| Pattern: |
Regionally restricted |
| Stage: |
TS20 |
| Assay Id: |
MGI:6273776 |
| Age: |
embryonic day 12.5 |
| Image: |
S2F/H |
| Note: |
Expression in region of lower tissue density corresponding to prospective vertebral bodies. Authors report expression in extracellular matrix, rather than on the surface of vertebral body cells. |
| Specimen Label: |
S2F/H |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6452813 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-09-03 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933620 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:6452816 |
| Age: |
embryonic day 12.5 |
|
|
| Specimen Label: |
2D |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6452813 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-09-03 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933620 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:6452816 |
| Age: |
embryonic day 12.5 |
|
|
| Specimen Label: |
2E |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6452813 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-09-03 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933620 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:6452816 |
| Age: |
embryonic day 12.5 |
|
|
| Specimen Label: |
2F |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6452813 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-09-03 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933620 |
| Pattern: |
Regionally restricted |
| Stage: |
TS20 |
| Assay Id: |
MGI:6452816 |
| Age: |
embryonic day 12.5 |
|
|
| Specimen Label: |
2H |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6452813 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-09-03 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1933620 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:6452816 |
| Age: |
embryonic day 12.5 |
|
|
| Specimen Label: |
2I |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|