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Search results 501 to 600 out of 832 for C4b

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Hits by Strain

Type Details Score
Publication
2459056 | J:9387
First Author: Aldrich CJ
Year: 1988
Journal: Immunogenetics
Title: Regulation of Qa-1 expression and determinant modification by an H-2D-linked gene, Qdm.
Volume: 28
Issue: 5
Pages: 334-44
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Publication
10583609 | J:58375
First Author: Schlaf G
Year: 1999
Journal: Immunology
Title: Rat complement factor I: molecular cloning, sequencing and expression in tissues and isolated cells.
Volume: 98
Issue: 3
Pages: 464-74
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Publication
3902620 | J:30951
 
First Author: White PC
Year: 1985
Journal: Immunol Rev
Title: Adrenal 21-hydroxylase cytochrome P-450 genes within the MHC class III region.
Volume: 87
Pages: 123-50
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Publication
1618655 | J:1850
First Author: Kawaguchi H
Year: 1992
Journal: Hum Immunol
Title: Organization of C4 and CYP21 loci in gorilla and orangutan.
Volume: 33
Issue: 3
Pages: 153-62
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Publication
32153567 | J:308437
 
First Author: Holers VM
Year: 2020
Journal: Front Immunol
Title: Key Components of the Complement Lectin Pathway Are Not Only Required for the Development of Inflammatory Arthritis but Also Regulate the Transcription of Factor D.
Volume: 11
Pages: 201
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Publication
10946292 | -
First Author: Matsushita M
Year: 2000
Journal: J Immunol
Title: Proteolytic activities of two types of mannose-binding lectin-associated serine protease.
Volume: 165
Issue: 5
Pages: 2637-42
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Protein
P08607
Organism: Mus musculus/domesticus
Length: 469  
Fragment?: false
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Protein
Q01339
Organism: Mus musculus/domesticus
Length: 345  
Fragment?: false
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Protein
Q60819
Organism: Mus musculus/domesticus
Length: 263  
Fragment?: false
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Protein
P01590
Organism: Mus musculus/domesticus
Length: 268  
Fragment?: false
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Protein
Q8BH32
Organism: Mus musculus/domesticus
Length: 490  
Fragment?: false
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Protein
Q8BGE4
Organism: Mus musculus/domesticus
Length: 302  
Fragment?: false
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Protein
Q60736
Organism: Mus musculus/domesticus
Length: 579  
Fragment?: false
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Protein
Q80SX2
Organism: Mus musculus/domesticus
Length: 426  
Fragment?: false
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Protein
Q3U749
Organism: Mus musculus/domesticus
Length: 302  
Fragment?: false
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Protein
Q3UW06
Organism: Mus musculus/domesticus
Length: 469  
Fragment?: false
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Protein
Q3TAS1
Organism: Mus musculus/domesticus
Length: 268  
Fragment?: false
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Protein
A0A0A6YWB1
Organism: Mus musculus/domesticus
Length: 113  
Fragment?: true
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Protein
Q8C2H9
Organism: Mus musculus/domesticus
Length: 268  
Fragment?: false
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Protein
G3X970
Organism: Mus musculus/domesticus
Length: 579  
Fragment?: false
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Protein
Q6LAL7
Organism: Mus musculus/domesticus
Length: 323  
Fragment?: true
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Protein
Q6ZQF4
Organism: Mus musculus/domesticus
Length: 324  
Fragment?: true
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Protein
Q9CY42
Organism: Mus musculus/domesticus
Length: 345  
Fragment?: false
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Protein
A0A0A6YY90
Organism: Mus musculus/domesticus
Length: 148  
Fragment?: true
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Protein
E9PZ07
Organism: Mus musculus/domesticus
Length: 535  
Fragment?: false
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Protein
A0A0A6YX15
Organism: Mus musculus/domesticus
Length: 104  
Fragment?: true
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Protein
Q3TP03
Organism: Mus musculus/domesticus
Length: 302  
Fragment?: false
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Protein
E9PVX4
Organism: Mus musculus/domesticus
Length: 514  
Fragment?: false
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Protein
Q8C0M5
Organism: Mus musculus/domesticus
Length: 323  
Fragment?: false
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Protein
Q544I2
Organism: Mus musculus/domesticus
Length: 268  
Fragment?: false
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Protein
Q0VET1
Organism: Mus musculus/domesticus
Length: 579  
Fragment?: false
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Publication
3034587 | J:8714
First Author: Müller U
Year: 1987
Journal: EMBO J
Title: Orientation and molecular map position of the complement genes in the mouse MHC.
Volume: 6
Issue: 2
Pages: 369-73
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Publication
18424734 | J:134537
First Author: Takahashi M
Year: 2008
Journal: J Immunol
Title: Mannose-binding lectin (MBL)-associated serine protease (MASP)-1 contributes to activation of the lectin complement pathway.
Volume: 180
Issue: 9
Pages: 6132-8
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Publication
9794427 | J:50500
First Author: Endo Y
Year: 1998
Journal: J Immunol
Title: Two lineages of mannose-binding lectin-associated serine protease (MASP) in vertebrates.
Volume: 161
Issue: 9
Pages: 4924-30
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Publication
24349316 | J:209864
First Author: Ali YM
Year: 2013
Journal: PLoS One
Title: Human L-ficolin, a recognition molecule of the lectin activation pathway of complement, activates complement by binding to pneumolysin, the major toxin of Streptococcus pneumoniae.
Volume: 8
Issue: 12
Pages: e82583
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Publication
21865552 | J:179342
First Author: Iwaki D
Year: 2011
Journal: J Immunol
Title: The role of mannose-binding lectin-associated serine protease-3 in activation of the alternative complement pathway.
Volume: 187
Issue: 7
Pages: 3751-8
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Publication
31399515 | J:279043
First Author: Hayashi M
Year: 2019
Journal: J Immunol
Title: Cutting Edge: Role of MASP-3 in the Physiological Activation of Factor D of the Alternative Complement Pathway.
Volume: 203
Issue: 6
Pages: 1411-1416
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Publication
17182967 | J:117801
First Author: Møller-Kristensen M
Year: 2007
Journal: Int Immunol
Title: Cooperation between MASP-1 and MASP-2 in the generation of C3 convertase through the MBL pathway.
Volume: 19
Issue: 2
Pages: 141-9
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Protein
Q9R0M3
Organism: Mus musculus/domesticus
Length: 464  
Fragment?: false
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Protein
Q9QUF7
Organism: Mus musculus/domesticus
Length: 535  
Fragment?: true
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Protein
A2BE45
Organism: Mus musculus/domesticus
Length: 444  
Fragment?: false
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Protein
Q3TYN1
Organism: Mus musculus/domesticus
Length: 674  
Fragment?: true
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Protein
Q9Z0D8
Organism: Mus musculus/domesticus
Length: 535  
Fragment?: true
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Protein
Q9Z0J3
Organism: Mus musculus/domesticus
Length: 535  
Fragment?: true
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Protein
F6TFC9
Organism: Mus musculus/domesticus
Length: 246  
Fragment?: true
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Protein
Q9QUF9
Organism: Mus musculus/domesticus
Length: 535  
Fragment?: true
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Protein
V9GZP9
Organism: Mus musculus/domesticus
Length: 200  
Fragment?: true
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Protein
Q3UWM1
Organism: Mus musculus/domesticus
Length: 199  
Fragment?: true
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Protein
Q3TAT4
Organism: Mus musculus/domesticus
Length: 674  
Fragment?: true
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Protein
G3UZS2
Organism: Mus musculus/domesticus
Length: 62  
Fragment?: true
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Protein
Q9QUF8
Organism: Mus musculus/domesticus
Length: 535  
Fragment?: true
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Protein
A0A0A6YW25
Organism: Mus musculus/domesticus
Length: 100  
Fragment?: true
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Publication
2566557 | J:9797
First Author: Bruisten SM
Year: 1989
Journal: Genetics
Title: Haplotype-specific interactions of non-H-2-linked genetic factors controlling the mouse C4 and Slp protein levels.
Volume: 121
Issue: 4
Pages: 795-801
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Publication
16328467 | J:194457
First Author: Endo Y
Year: 2005
Journal: Immunogenetics
Title: Carbohydrate-binding specificities of mouse ficolin A, a splicing variant of ficolin A and ficolin B and their complex formation with MASP-2 and sMAP.
Volume: 57
Issue: 11
Pages: 837-44
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Publication
31869396 | J:292499
First Author: Bibert S
Year: 2019
Journal: PLoS Pathog
Title: Herpes simplex encephalitis in adult patients with MASP-2 deficiency.
Volume: 15
Issue: 12
Pages: e1008168
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Publication
24740308 | J:215201
First Author: Dib S
Year: 2014
Journal: PLoS One
Title: Gene targeting of mouse Tardbp negatively affects Masp2 expression.
Volume: 9
Issue: 4
Pages: e95373
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Publication
15672593 | J:94068
First Author: Stover CM
Year: 2004
Journal: Mamm Genome
Title: Organization of the MASP2 locus and its expression profile in mouse and rat.
Volume: 15
Issue: 11
Pages: 887-900
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Publication
28739878 | J:251071
First Author: Banda NK
Year: 2017
Journal: J Immunol
Title: Deconstructing the Lectin Pathway in the Pathogenesis of Experimental Inflammatory Arthritis: Essential Role of the Lectin Ficolin B and Mannose-Binding Protein-Associated Serine Protease 2.
Volume: 199
Issue: 5
Pages: 1835-1845
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Protein
Q923L3
Organism: Mus musculus/domesticus
Length: 3564  
Fragment?: false
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Protein
Q80T79
Organism: Mus musculus/domesticus
Length: 3707  
Fragment?: false
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Protein
Q501P1
Organism: Mus musculus/domesticus
Length: 440  
Fragment?: false
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Protein
Q6P1D5
Organism: Mus musculus/domesticus
Length: 963  
Fragment?: false
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Protein
Q8R054
Organism: Mus musculus/domesticus
Length: 468  
Fragment?: false
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Protein
Q4V9Z5
Organism: Mus musculus/domesticus
Length: 910  
Fragment?: false
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Protein
Q7TSK2
Organism: Mus musculus/domesticus
Length: 991  
Fragment?: false
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Protein
Q62237
Organism: Mus musculus/domesticus
Length: 141  
Fragment?: true
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Protein
A0A0U1RNQ8
Organism: Mus musculus/domesticus
Length: 136  
Fragment?: true
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Protein
Q52KF2
Organism: Mus musculus/domesticus
Length: 490  
Fragment?: true
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Protein
V9GX34
Organism: Mus musculus/domesticus
Length: 3611  
Fragment?: false
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Protein
A0A1D5RMI4
Organism: Mus musculus/domesticus
Length: 964  
Fragment?: false
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Protein
F6TRD7
Organism: Mus musculus/domesticus
Length: 2797  
Fragment?: true
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Protein
A0A0R4J0Y4
Organism: Mus musculus/domesticus
Length: 962  
Fragment?: false
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Protein
Q5DTK7
Organism: Mus musculus/domesticus
Length: 761  
Fragment?: true
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Protein
Q80WW7
Organism: Mus musculus/domesticus
Length: 339  
Fragment?: true
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Protein
E9PWJ0
Organism: Mus musculus/domesticus
Length: 3538  
Fragment?: false
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Protein
A0A1D5RMJ7
Organism: Mus musculus/domesticus
Length: 887  
Fragment?: false
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Protein
F6SXT0
Organism: Mus musculus/domesticus
Length: 278  
Fragment?: true
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Protein
V9H0U1
Organism: Mus musculus/domesticus
Length: 195  
Fragment?: true
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Protein
Q80TP0
Organism: Mus musculus/domesticus
Length: 713  
Fragment?: true
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Protein
A0A0G2JG23
Organism: Mus musculus/domesticus
Length: 897  
Fragment?: false
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Protein
F6XNR8
Organism: Mus musculus/domesticus
Length: 452  
Fragment?: true
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Protein
G3UW60
Organism: Mus musculus/domesticus
Length: 619  
Fragment?: false
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Protein
A0A0G2JFG4
Organism: Mus musculus/domesticus
Length: 714  
Fragment?: true
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Protein
Q505G3
Organism: Mus musculus/domesticus
Length: 448  
Fragment?: false
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Protein
Q3UMG7
Organism: Mus musculus/domesticus
Length: 317  
Fragment?: false
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Protein
A2AN91
Organism: Mus musculus/domesticus
Length: 699  
Fragment?: false
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Protein
Q571B7
Organism: Mus musculus/domesticus
Length: 1806  
Fragment?: true
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Protein
Q3TR50
Organism: Mus musculus/domesticus
Length: 228  
Fragment?: true
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Publication
14563677 | J:86324
First Author: Krebs CJ
Year: 2003
Journal: Genes Dev
Title: Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.
Volume: 17
Issue: 21
Pages: 2664-74
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Protein
A0A0G2JF07
Organism: Mus musculus/domesticus
Length: 145  
Fragment?: true
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Publication
7979249 | -
 
First Author: Krieger M
Year: 1994
Journal: Annu Rev Biochem
Title: Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related protein (LRP).
Volume: 63
Pages: 601-37
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Publication
7548065 | -
First Author: Bieri S
Year: 1995
Journal: Biochemistry
Title: Disulfide bridges of a cysteine-rich repeat of the LDL receptor ligand-binding domain.
Volume: 34
Issue: 40
Pages: 13059-65
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Publication
3283935 | -
First Author: Mahley RW
Year: 1988
Journal: Science
Title: Apolipoprotein E: cholesterol transport protein with expanding role in cell biology.
Volume: 240
Issue: 4852
Pages: 622-30
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Protein Domain
IPR023415 | LDLR_class-A_CS
Type: Conserved_site
Description: Low-density lipoprotein (LDL) receptors are the major cholesterol-carrying lipoproteins of plasma. Seven successive cysteine-rich repeats of about 40 amino acids are present in the N-terminal of this multidomain membrane protein []. Similar domains have been found (see references in []) in other extracellular and membrane proteins which are listed below: Vertebrate very low density lipoprotein (VLDL) receptor, which binds and transports VLDL. Its extracellular domain is composed of 8 LDLRA domains, 3 EGF-like domains and 6 LDL-receptor class B domains (LDLRB). Vertebrate low-density lipoprotein receptor-related protein 1 (LRP1) (reviewed in []), which may act as a receptor for the endocytosis of extracellular ligands. LRP1 contains 31 LDLRA domains and 22 EGF-like domains. Vertebrate low-density lipoprotein receptor-related protein 2 (LRP2) (also known as gp330 or megalin). LRP2 contains 36 LDLRA domains and 17 EGF-like domains. A LRP-homologue from Caenorhabditis elegans, which contains 35 LDLRA domains and 17 EGF-like domains. Drosophila putative vitellogenin receptor, with 13 copies of LDLRA domains and 17 EGF-like repeats. Complement factor I, which is responsible for cleaving the alpha-chains of C4b and C3b. It consists of a FIMAC domain (Factor I/MAC proteins C6/C7), a scavenger receptor-like domain, 2 copies of LDLRA and a C-terminal serine protease domain. Complement components C6, C7, C8 and C9. They contain each one LDLRA domain. Perlecan, a large multidomain basement membrane heparan sulphate proteoglycan composed of 4 LDLRA domains, 3 LamB domains, 12 laminin EGF- like domains, 14-21 IG-like domains, 3 LamG domains, and 4 EGF-like domains. A similar but shorter proteoglycan (UNC52) is found in Caenorhabditis elegans which has 3 repeats of LDLRA. Invertebrate giant extracellular hemoglobin linker chains, which allow heme-containing chains to construct giant hemoglobin (1 LDLRA domain). G-protein coupled receptor Grl101 of the snail Lymnaea stagnalis, which might directly transduce signals carried by large extracellular proteins. Vertebrate enterokinase (EC 3.4.21.9), a type II membrane protein of the intestinal brush border, which activates trypsinogen. It consists at least of a catalytic light chain and a multidomain heavy chain which has 2 LDLRA, a MAM domain (see ), a SRCR domain (see ) and a CUB domain (see ).Human autosomal dominant polycystic kidney disease protein 1 (PKD1), which is involved in adhesive protein-protein and protein-carbohydrate interactions. The potential calcium-binding site of its single LDLRA domain is missing. Vertebrate integral membrane protein DGCR2/IDD, a potential adhesion receptor with 1 LDLRA domain, a C-type lectin and a VWFC domain (see ).Drosophila serine protease nudel (EC 3.4.21.-), which is involved in the induction of dorsoventral polarity of the embryo. It has 11 LDLRA domains, 3 of which miss the first disulphide bond (C1-C3). Avian subgroup A rous sarcoma virus receptor (1 copy of LDLRA). Bovine Sco-spondin, which is secreted by the subcommissural organ in embryos and is involved in the modulation of neuronal aggregation. It contains at least 2 EGF-like domains and 3 LDLRA domains. The LDL-receptor class A domain contains 6 disulphide-bound cysteines []and a highly conserved cluster of negatively charged amino acids, of which many are clustered on one face of the module []. A schematic representation of this domain is shown here: +---------------------+ +--------------------------------+| | | |-CxxxxxxxxxxxxCxxxxxxxxCxxxxxxxxCxxxxxxxxxxCxxxxxxxxxxxxxxxxxxxxxC-|*******************************************| |+----------------------------+'C': conserved cysteine involved in a disulphide bond.'x': any residue.'*': position of the pattern.In LDL-receptors the class A domains form the binding site for LDL []and calcium. The acidic residues between the fourth and sixth cysteines are important for high-affinity binding of positively charged sequences in LDLR's ligands []. The repeat has been shown []to consist of a β-hairpin structure followed by a series of β-turns. The binding of calcium seems to induce no significant conformational change.
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Protein
Q8R4K8
Organism: Mus musculus/domesticus
Length: 1624  
Fragment?: false
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Protein
Q9DBX3
Organism: Mus musculus/domesticus
Length: 820  
Fragment?: false
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Protein
O88305
Organism: Mus musculus/domesticus
Length: 383  
Fragment?: true
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Protein
B2RY76
Organism: Mus musculus/domesticus
Length: 752  
Fragment?: false
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Protein
Q6P3Y0
Organism: Mus musculus/domesticus
Length: 371  
Fragment?: true
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Protein
Q3UAS8
Organism: Mus musculus/domesticus
Length: 411  
Fragment?: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom