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Search results 501 to 600 out of 1059 for Casp8

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Type Details Score
Publication
30485804 | J:270778
First Author: Vince JE
Year: 2018
Journal: Cell Rep
Title: The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation.
Volume: 25
Issue: 9
Pages: 2339-2353.e4
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Publication
25693118 | J:221796
 
First Author: Lawlor KE
Year: 2015
Journal: Nat Commun
Title: RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL.
Volume: 6
Pages: 6282
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Publication
10618441 | J:59317
First Author: Roth KA
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Epistatic and independent functions of caspase-3 and Bcl-X(L) in developmental programmed cell death.
Volume: 97
Issue: 1
Pages: 466-71
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Publication
37553330 | J:338931
First Author: Matsui Y
Year: 2023
Journal: Nat Commun
Title: SNIP1 and PRC2 coordinate cell fates of neural progenitors during brain development.
Volume: 14
Issue: 1
Pages: 4754
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Publication
29203883 | J:265712
First Author: Dziedzic SA
Year: 2018
Journal: Nat Cell Biol
Title: ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC.
Volume: 20
Issue: 1
Pages: 58-68
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Publication
11241200 | J:67809
First Author: Melnick M
Year: 2001
Journal: Anat Rec
Title: Embryonic mouse submandibular salivary gland morphogenesis and the TNF/TNF-R1 signal transduction pathway.
Volume: 262
Issue: 3
Pages: 318-30
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Publication
19801895 | J:155983
First Author: Ikeda T
Year: 2009
Journal: J Vet Med Sci
Title: Expression of caspase family and muscle- and apoptosis-specific genes during skeletal myogenesis in mouse embryo.
Volume: 71
Issue: 9
Pages: 1161-8
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Publication
33060561 | J:313943
First Author: Cao S
Year: 2020
Journal: Cell Death Dis
Title: Restoring BMP4 expression in vascular endothelial progenitors ameliorates maternal diabetes-induced apoptosis and neural tube defects.
Volume: 11
Issue: 10
Pages: 859
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Publication
35859175 | J:330287
First Author: de Reuver R
Year: 2022
Journal: Nature
Title: ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation.
Volume: 607
Issue: 7920
Pages: 784-789
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Publication
34471287 | J:361095
First Author: Lee S
Year: 2021
Journal: Nature
Title: AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence.
Volume: 597
Issue: 7876
Pages: 415-419
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Publication
27917412 | J:290369
 
First Author: Kuriakose T
Year: 2016
Journal: Sci Immunol
Title: ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways.
Volume: 1
Issue: 2
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Publication
27709293 | J:261957
First Author: Svandova EB
Year: 2017
Journal: Histochem Cell Biol
Title: Expression of Fas, FasL, caspase-8 and other factors of the extrinsic apoptotic pathway during the onset of interdigital tissue elimination.
Volume: 147
Issue: 4
Pages: 497-510
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Publication
35139355 | J:324833
First Author: Simpson DS
Year: 2022
Journal: Immunity
Title: Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway.
Volume: 55
Issue: 3
Pages: 423-441.e9
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Publication
11707574 | J:72978
First Author: Farmer MA
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: A major quantitative trait locus on chromosome 3 controls colitis severity in IL-10-deficient mice.
Volume: 98
Issue: 24
Pages: 13820-5
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Publication
33278357 | J:361144
First Author: Karki R
Year: 2021
Journal: Cell
Title: Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes.
Volume: 184
Issue: 1
Pages: 149-168.e17
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Publication
38409108 | J:361094
First Author: Han JH
Year: 2024
Journal: Nat Commun
Title: NINJ1 mediates inflammatory cell death, PANoptosis, and lethality during infection conditions and heat stress.
Volume: 15
Issue: 1
Pages: 1739
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Publication
26383973 | J:239805
First Author: Grigaravicius P
Year: 2016
Journal: Cell Death Differ
Title: Rint1 inactivation triggers genomic instability, ER stress and autophagy inhibition in the brain.
Volume: 23
Issue: 3
Pages: 454-68
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Publication
17276340 | J:119922
First Author: Mailleux AA
Year: 2007
Journal: Dev Cell
Title: BIM regulates apoptosis during mammary ductal morphogenesis, and its absence reveals alternative cell death mechanisms.
Volume: 12
Issue: 2
Pages: 221-34
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Publication
32141129 | J:294650
First Author: Hemker SL
Year: 2020
Journal: FASEB J
Title: Deletion of hypoxia-responsive microRNA-210 results in a sex-specific decrease in nephron number.
Volume: 34
Issue: 4
Pages: 5782-5799
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Publication
30655546 | J:270211
First Author: Yang P
Year: 2019
Journal: Nat Commun
Title: Tip60- and sirtuin 2-regulated MARCKS acetylation and phosphorylation are required for diabetic embryopathy.
Volume: 10
Issue: 1
Pages: 282
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Publication
24741061 | J:210623
First Author: Yeh ML
Year: 2014
Journal: J Neurosci
Title: Robo1 modulates proliferation and neurogenesis in the developing neocortex.
Volume: 34
Issue: 16
Pages: 5717-31
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Publication
28474670 | J:250342
 
First Author: Wang F
Year: 2017
Journal: Nat Commun
Title: Protein kinase C-alpha suppresses autophagy and induces neural tube defects via miR-129-2 in diabetic pregnancy.
Volume: 8
Pages: 15182
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Publication
28410990 | J:254534
First Author: Gurung P
Year: 2017
Journal: Immunity
Title: Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease.
Volume: 46
Issue: 4
Pages: 635-648
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Publication
21880664 | J:177567
First Author: Li D
Year: 2011
Journal: Hum Mol Genet
Title: Restrictive loss of plakoglobin in cardiomyocytes leads to arrhythmogenic cardiomyopathy.
Volume: 20
Issue: 23
Pages: 4582-96
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Publication
26173459 | J:226104
First Author: Wang F
Year: 2015
Journal: Am J Physiol Endocrinol Metab
Title: ASK1 mediates the teratogenicity of diabetes in the developing heart by inducing ER stress and inhibiting critical factors essential for cardiac development.
Volume: 309
Issue: 5
Pages: E487-99
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Publication
39747033 | J:360776
First Author: Di Michele M
Year: 2025
Journal: Nat Commun
Title: E4F1 coordinates pyruvate metabolism and the activity of the elongator complex to ensure translation fidelity during brain development.
Volume: 16
Issue: 1
Pages: 67
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
16964442 | J:112870
First Author: Mager J
Year: 2006
Journal: Mamm Genome
Title: Identification of candidate maternal-effect genes through comparison of multiple microarray data sets.
Volume: 17
Issue: 9
Pages: 941-9
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
37702066 | J:341382
First Author: Wu B
Year: 2023
Journal: J Am Heart Assoc
Title: Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development.
Volume: 12
Issue: 18
Pages: e029683
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:104190
     
First Author: The Australian Phenomics Facility at The Australian National University
Year: 2006
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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Publication
- | J:24194
     
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Protein Coding Gene
MGI:1336166 | Cflar
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
9289491 | J:42098
First Author: Goltsev YV
Year: 1997
Journal: J Biol Chem
Title: CASH, a novel caspase homologue with death effector domains.
Volume: 272
Issue: 32
Pages: 19641-4
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Publication
9217161 | J:41473
First Author: Irmler M
Year: 1997
Journal: Nature
Title: Inhibition of death receptor signals by cellular FLIP.
Volume: 388
Issue: 6638
Pages: 190-5
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Protein
O35732
Organism: Mus musculus/domesticus
Length: 481  
Fragment?: false
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Publication
26798068 | J:244556
First Author: Ram DR
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Balance between short and long isoforms of cFLIP regulates Fas-mediated apoptosis in vivo.
Volume: 113
Issue: 6
Pages: 1606-11
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UniProt Feature
UniProt Feature
Begin: 371
Description: Cleavage; by CASP8
Type: site
End: 372
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UniProt Feature
UniProt Feature
Begin: 377
Description: Cleavage; by CASP8
Type: site
End: 378
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UniProt Feature
UniProt Feature
Begin: 169
Description: Cleavage; by CASP8
Type: site
End: 170
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UniProt Feature
UniProt Feature
Begin: 156
Description: Cleavage; by CASP8
Type: site
End: 157
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UniProt Feature
UniProt Feature
Begin: 325
Description: Cleavage; by CASP8
Type: site
End: 326
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UniProt Feature
UniProt Feature
Begin: 200
Description: Cleavage; by CASP8
Type: site
End: 201
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UniProt Feature
UniProt Feature
Begin: 488
Description: Cleavage; by CASP8
Type: site
End: 489
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Publication
29191940 | J:271426
First Author: Gehrke N
Year: 2018
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Loss of cellular FLICE-inhibitory protein promotes acute cholestatic liver injury and inflammation from bile duct ligation.
Volume: 314
Issue: 3
Pages: G319-G333
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Publication
21703207 | J:272080
First Author: Schattenberg JM
Year: 2011
Journal: J Hepatol
Title: Ablation of c-FLIP in hepatocytes enhances death-receptor mediated apoptosis and toxic liver injury in vivo.
Volume: 55
Issue: 6
Pages: 1272-80
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HT Experiment
GSE125625 | CASP8 C362A KI MLKL KO e16.5 intestine RNAseq
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Gene
488471 | CFLAR
Type: gene
Organism: dog, domestic
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Gene
459872 | CFLAR
Type: gene
Organism: chimpanzee
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Gene
497199 | CFLAR
Type: gene
Organism: cattle
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Gene
424080 | CFLAR
Type: gene
Organism: chicken
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Gene
373114 | cflara
Type: gene
Organism: zebrafish
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Gene
574234 | CFLAR
Type: gene
Organism: macaque, rhesus
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Gene
779578 | cflar
Type: gene
Organism: frog, western clawed
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Gene
108701437 | cflar.L
Type: gene
Organism: frog, African clawed
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Gene
780745 | cflar.S
Type: gene
Organism: frog, African clawed
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Pathway
R-MMU-5218900 | CASP8 activity is inhibited
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Publication
18832693 | J:140768
First Author: Zhang N
Year: 2008
Journal: J Immunol
Title: c-FLIP protects mature T lymphocytes from TCR-mediated killing.
Volume: 181
Issue: 8
Pages: 5368-73
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Publication
20975036 | J:323312
First Author: Li H
Year: 2010
Journal: Hypertension
Title: Cellular FLICE-inhibitory protein protects against cardiac remodeling induced by angiotensin II in mice.
Volume: 56
Issue: 6
Pages: 1109-17
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Publication
23175183 | J:205617
First Author: He MX
Year: 2013
Journal: Cell Death Differ
Title: A role for c-FLIP(L) in the regulation of apoptosis, autophagy, and necroptosis in T lymphocytes.
Volume: 20
Issue: 2
Pages: 188-97
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Publication
38824526 | J:351982
First Author: Yang X
Year: 2024
Journal: J Neuroinflammation
Title: cFLIP in the molecular regulation of astroglia-driven neuroinflammation in experimental glaucoma.
Volume: 21
Issue: 1
Pages: 145
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Component
Component
Name: CASP8 and FADD-like apoptosis regulator subunit p43
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Component
Component
Name: CASP8 and FADD-like apoptosis regulator subunit p12
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Protein
Q5U4G3
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: false
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Publication
22406316 | J:183243
First Author: Schattenberg JM
Year: 2012
Journal: Free Radic Biol Med
Title: The role of death effector domain-containing proteins in acute oxidative cell injury in hepatocytes.
Volume: 52
Issue: 9
Pages: 1911-7
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Protein
A0A2C9F2D9
Organism: Mus musculus/domesticus
Length: 484  
Fragment?: false
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Protein
Q812G4
Organism: Mus musculus/domesticus
Length: 481  
Fragment?: false
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Protein
O35732-2
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: false
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Publication
23250397 | J:259529
First Author: Piao X
Year: 2012
Journal: Sci Signal
Title: c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis.
Volume: 5
Issue: 255
Pages: ra93
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Publication
16043517 | J:100558
First Author: Zhang N
Year: 2005
Journal: J Exp Med
Title: An essential role for c-FLIP in the efficient development of mature T lymphocytes.
Volume: 202
Issue: 3
Pages: 395-404
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Publication
24209745 | J:205130
First Author: Panayotova-Dimitrova D
Year: 2013
Journal: Cell Rep
Title: cFLIP regulates skin homeostasis and protects against TNF-induced keratinocyte apoptosis.
Volume: 5
Issue: 2
Pages: 397-408
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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