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Search results 501 to 600 out of 1539 for Cat

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Type Details Score
Publication
31647781 | J:287955
 
First Author: Neves KB
Year: 2019
Journal: JCI Insight
Title: ER stress and Rho kinase activation underlie the vasculopathy of CADASIL.
Volume: 4
Issue: 23
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Publication
24451386 | J:212054
First Author: Lagrange J
Year: 2014
Journal: FASEB J
Title: Endothelial mineralocorticoid receptor activation enhances endothelial protein C receptor and decreases vascular thrombosis in mice.
Volume: 28
Issue: 5
Pages: 2062-72
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Protein Coding Gene
MGI:88564 | Ctsl
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1927259 | Trpv6
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2136976 | Hdhd5
Type: protein_coding_gene
Organism: mouse, laboratory
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MP Term
MP:0011592 | abnormal catalase activity
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MP Term
MP:0011593 | increased catalase activity
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MP Term
MP:0011594 | decreased catalase activity
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Allele
Tg(CAG-cat,-Gdf10)1Ncvcb | MGI:7384448
Name: transgene insertion 1, National Cerebral and Cardiovascular Center Research Institute
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Strain
MGI:6353737 | C57BL/6J-Tg(Fabp4-Cat)1Ish/IshRbrc
Attribute String: coisogenic, mutant strain, transgenic
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Strain
MGI:6353058 | STOCK Tg(CAG-Gsk3b,-cat)5-6Sfu/SfuRbrc
Attribute String: transgenic, mutant stock
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Strain
MGI:6353059 | STOCK Tg(CAG-Gsk3b,-cat)5-7Sfu/SfuRbrc
Attribute String: mutant stock, transgenic
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Strain
MGI:6353060 | STOCK Tg(CAG-Gsk3b,-cat)5-8Sfu/SfuRbrc
Attribute String: transgenic, mutant stock
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Strain
MGI:6353057 | STOCK Tg(CAG-Gsk3b,-cat)5-5Sfu/SfuRbrc
Attribute String: transgenic, mutant stock
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Allele
Gt(ROSA)26Sor<tm1.1(CAG-AKR1C3)Watk> | MGI:7526275
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Kikuko Watanabe
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Allele
Tg(CAG-cat,-spH)5Yyan | MGI:7518737
Name: transgene insertion 5, Yuchio Yanagawa
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
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Strain
MGI:6146166 | C57BL/6-Tg(Ckm-Hbegf,-cat)1Maka/Rbrc
Attribute String: mutant strain, coisogenic, transgenic
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Publication
19264873 | J:158185
First Author: Fukatsu Y
Year: 2009
Journal: Endocrinology
Title: Muscle-specific overexpression of heparin-binding epidermal growth factor-like growth factor increases peripheral glucose disposal and insulin sensitivity.
Volume: 150
Issue: 6
Pages: 2683-91
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Allele
Igs2<tm1(CAG-EGFP,-CAT,-Cmah)Avrk> | MGI:7607015
Name: intergenic site 2; targeted mutation 1, Ajit Varki
Allele Type: Targeted
Attribute String: Inserted expressed sequence, Reporter
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Allele
Tg(CAG-cat,-Dll1)1Yoku | MGI:7610644
Name: transgene insertion 1, Yusuke Okubo
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
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Strain
MGI:7610802 | STOCK Tg(CAG-cat,-Dll1)1Yoku/Rbrc
Attribute String: mutant stock, transgenic
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Publication
32065054 | J:297706
First Author: Nosalski R
Year: 2020
Journal: Circ Res
Title: T-Cell-Derived miRNA-214 Mediates Perivascular Fibrosis in Hypertension.
Volume: 126
Issue: 8
Pages: 988-1003
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Publication
25966493 | J:277104
First Author: Urbanet R
Year: 2015
Journal: Hypertension
Title: Adipocyte Mineralocorticoid Receptor Activation Leads to Metabolic Syndrome and Induction of Prostaglandin D2 Synthase.
Volume: 66
Issue: 1
Pages: 149-57
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Protein Coding Gene
MGI:96990 | Mip
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1923799 | Cecr2
Type: protein_coding_gene
Organism: mouse, laboratory
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Allele
Tg(CAG-cat,-Hand1)2Ysa | MGI:6149526
Name: transgene insertion 2, Yumiko Saga
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Allele
Tg(CAG-cat,-Hand2)1Ysa | MGI:6149531
Name: transgene insertion 1, Yumiko Saga
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Allele
Tg(Myh6-Mtg1)3Ywxu | MGI:6362670
Name: transgene insertion 3, Yawei Xu
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(CAG-CAT,-Ube2i)#Wgcy | MGI:6759414
Name: transgene insertion, Cong-Yi Wang
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
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Strain
MGI:6147185 | B6;CB-Gt(ROSA)26Sor<tm1.1(CAG-AKR1C3)Watk>/WatkRbrc
Attribute String: mutant stock, targeted mutation
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Strain
MGI:6146340 | B6.Cg-Tg(CAG-cat,-spH)5Yyan/Rbrc
Attribute String: mutant strain, congenic, transgenic
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Strain
MGI:7607287 | B6.Cg-Igs2<tm1(CAG-EGFP,-CAT,-Cmah)Avrk>/Mmucd
Attribute String: congenic, mutant strain, targeted mutation
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GO Term
GO:1902551 | regulation of catalase activity
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Interaction Term
MI:0370 | tox-r dimerization assay
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Protein Domain
IPR032776 | CECR6/TMEM121
Type: Family
Description: This family includes Cat eye syndrome critical region protein 6 (also known as TMEM121B), a protein which has been identified in a screen for candidate genes for the developmental disorder Cat Eye Syndrome (CES) []. It also includes the TMEM121 transmembrane proteins. The function of this family is unknown.
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DO Term
DOID:9965 | toxoplasmosis
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Publication
15939817 | J:112171
First Author: Ouvrard-Pascaud A
Year: 2005
Journal: Circulation
Title: Conditional mineralocorticoid receptor expression in the heart leads to life-threatening arrhythmias.
Volume: 111
Issue: 23
Pages: 3025-33
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Allele
Tg(CAG-EGFP-CAT-lacZ)144-5Masa | MGI:3767444
Name: transgene insertion 144-5, Masahiro Sato
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(CAG-Calr)#Mlk | MGI:6108898
Name: transgene insertion, Marek Michalak
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence
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Allele
Pik3ca<tm4Bvan> | MGI:6115348
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; targeted mutation 4, Bart Vanhaesebroeck
Allele Type: Targeted
Attribute String: Hypomorph
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Strain
MGI:6144635 | ICR.Cg-Tg(CAG-cat,-Hand1)2Ysa/YsaRbrc
Attribute String: mutant strain, congenic, transgenic
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Strain
MGI:6144634 | ICR.Cg-Tg(CAG-cat,-Hand2)1Ysa/YsaRbrc
Attribute String: mutant strain, congenic, transgenic
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Allele
Tg(CAG-cat,-Traf3)4Holi | MGI:6153906
Name: transgene insertion 4, Hongliang Li
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Allele
Tg(CAG-cat,-Creg1)#Yal | MGI:6196857
Name: transgene insertion, Ya-Ling Han
Allele Type: Transgenic
Attribute String: Conditional ready, Knockdown, Reporter
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Allele
Tg(CAG-cat,-Dusp14)4Lyg | MGI:6197022
Name: transgene insertion 4, Yi-Gang Li
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Allele
Jak1<tm1.1Hko> | MGI:6281710
Name: Janus kinase 1; targeted mutation 1.1, Haruhiko Koseki
Allele Type: Targeted
Attribute String: Not Specified
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Allele
Tbk1<em6Lutzy> | MGI:6295381
Name: TANK-binding kinase 1; endonuclease-mediated mutation 6, Cathy Lutz
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
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Allele
Tg(CAG-Dusp26)#Jhxia | MGI:6361754
Name: transgene insertion, Jiahong Xia
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Strain
MGI:7386841 | C57BL/6J-Tg(CAG-cat,-Gdf10)1Ncvcb/Ncvcb
Attribute String: coisogenic, mutant strain, transgenic
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Allele
Tg(CAG-cat,-Notch2)1Ysa | MGI:7495778
Name: transgene insertion 1, Yumiko Saga
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Allele
Tg(CAG-cat,-Notch2)2Ysa | MGI:7495786
Name: transgene insertion 2, Yumiko Saga
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Allele
Tg(CAG-Ccnd1,-cat,-EGFP)21Taket | MGI:7537203
Name: transgene insertion 21, Takashi Takeuchi
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
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Allele
Tg(CAG-Ccnd1,-cat,-EGFP)22Taket | MGI:7537204
Name: transgene insertion 22, Takashi Takeuchi
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
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Allele
Tg(CAG-Ccnd1,-cat,-EGFP)25Taket | MGI:7537205
Name: transgene insertion 25, Takashi Takeuchi
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
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Allele
Tg(CAG-Ccnd1,-cat,-EGFP)27Taket | MGI:7537206
Name: transgene insertion 27, Takashi Takeuchi
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
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Allele
Tg(CAG-Ccnd1,-cat,-EGFP)12Taket | MGI:7537267
Name: transgene insertion 12, Takashi Takeuchi
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Trim71<em1Ktka> | MGI:7661051
Name: tripartite motif-containing 71; endonuclease-mediated mutation 1, Kristopher T Kahle
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
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Genotype
Genotype
Symbol: Tg(Myh6-Mtg1)3Ywxu/?
Background: involves: C57BL/6J
Zygosity: ot
Has Mutant Allele: true
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Publication
2376597 | J:93006
First Author: Adrian GS
Year: 1990
Journal: J Biol Chem
Title: Human transferrin. Expression and iron modulation of chimeric genes in transgenic mice.
Volume: 265
Issue: 22
Pages: 13344-50
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Publication
33406423 | J:333975
First Author: Udagawa T
Year: 2021
Journal: Cell Rep
Title: Failure to Degrade CAT-Tailed Proteins Disrupts Neuronal Morphogenesis and Cell Survival.
Volume: 34
Issue: 1
Pages: 108599
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Protein Domain
IPR013659 | A_deaminase_N
Type: Domain
Description: This domain is found to the N terminus of the Adenosine/AMP deaminase domain () in metazoan proteins such as the Cat eye syndrome critical region protein 1 and its homologues.
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Protein
Q80XA0
Organism: Mus musculus/domesticus
Length: 318  
Fragment?: false
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Allele
Tg(CAG-cat,-lacZ)1Brn | MGI:3044043
Name: transgene insertion 1, Anton Berns
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(TF-CAT)48Gsa | MGI:3056737
Name: transgene insertion 48, Gwen S Adrian
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(CAG-cat,-Notch1)1Ysa | MGI:3702441
Name: transgene insertion 1, Yumiko Saga
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Publication
10737965 | J:128541
First Author: Sato M
Year: 2000
Journal: Mol Reprod Dev
Title: New approach to cell lineage analysis in mammals using the Cre-loxP system.
Volume: 56
Issue: 1
Pages: 34-44
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Allele
Tg(CAG-EGFP-CAT-DTA)2Masa | MGI:3767445
Name: transgene insertion 2, Masahiro Sato
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(CAG-cat,-Nanos2)1Ysa | MGI:3778826
Name: transgene insertion 1, Yumiko Saga
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(CAG-cat,-Il18)#Thos | MGI:5688534
Name: transgene insertion, Tomoaki Hoshino
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence
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Strain
MGI:7380783 | C57BL/6-Pik3ca<tm4Bvan>/H
Attribute String: coisogenic, mutant strain, targeted mutation
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Allele
App<em1Adiuj> | MGI:6164022
Name: amyloid beta precursor protein; endonuclease-mediated mutation 1, MODEL-AD Center
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
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Strain
MGI:6295412 | C57BL/6J-Tbk1<em6Lutzy>/J
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Tg(CAG-cat,-Mesp2)1Ysa | MGI:6324534
Name: transgene insertion 1, Yumiko Saga
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Allele
Picalm<em1Aduci> | MGI:6441030
Name: phosphatidylinositol binding clathrin assembly protein; endonuclease-mediated mutation 1, Frank LaFerla
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
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Allele
Tg(CAG-cat,-Dnd1)1Ysa | MGI:7469605
Name: transgene insertion 1, Yumiko Saga
Allele Type: Transgenic
Attribute String: Conditional ready, Epitope tag, Inserted expressed sequence, Reporter
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Allele
Tg(CAG-cat,-Pofut1)1Ysa | MGI:7506807
Name: transgene insertion 1, Yumiko Saga
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Allele
Tg(CAG-cat,-Bmp2)1Ysa | MGI:7506809
Name: transgene insertion 1, Yumiko Saga
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Allele
Tg(CAG-cat,-Nanos2)5Ysa | MGI:7507502
Name: transgene insertion 5, Yumiko Saga
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Allele
Tg(CAG-cat,-Nanos2)9Ysa | MGI:7507504
Name: transgene insertion 9, Yumiko Saga
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Allele
Tg(CAG-cat,-Stra8)1Ysa | MGI:7509206
Name: transgene insertion 1, Yumiko Saga
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Allele
Tg(CAG-cat,-Stra8)5Ysa | MGI:7509208
Name: transgene insertion 5, Yumiko Saga
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Strain
MGI:6144636 | STOCK Tg(CAG-cat,-Notch2)1Ysa/YsaRbrc
Attribute String: transgenic, mutant stock
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Strain
MGI:6144637 | STOCK Tg(CAG-cat,-Notch2)2Ysa/YsaRbrc
Attribute String: transgenic, mutant stock
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Allele
Tg(CAG-cat,-Mesp1)1Ysa | MGI:7495766
Name: transgene insertion 1, Yumiko Saga
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Allele
Tg(CAG-cat,-Nkx2-5)12Ysa | MGI:7495768
Name: transgene insertion 12, Yumiko Saga
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Allele
Tg(CAG-cat,-Nkx2-5)13Ysa | MGI:7495773
Name: transgene insertion 13, Yumiko Saga
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Strain
MGI:6353864 | STOCK Tg(CAG-Ccnd1,-cat,-EGFP)21Taket/TaketRbrc
Attribute String: transgenic, mutant stock
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Strain
MGI:6353865 | STOCK Tg(CAG-Ccnd1,-cat,-EGFP)22Taket/TaketRbrc
Attribute String: transgenic, mutant stock
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Strain
MGI:6353866 | STOCK Tg(CAG-Ccnd1,-cat,-EGFP)25Taket/TaketRbrc
Attribute String: transgenic, mutant stock
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Strain
MGI:6353867 | STOCK Tg(CAG-Ccnd1,-cat,-EGFP)27Taket/TaketRbrc
Attribute String: transgenic, mutant stock
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Strain
MGI:6353863 | STOCK Tg(CAG-Ccnd1,-cat,-EGFP)12Taket/TaketRbrc
Attribute String: transgenic, mutant stock
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Allele
Tg(CAG-cat,-Tcf25)1Xdgz | MGI:7628235
Name: transgene insertion 1, Xiao-Dong Zhang
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Allele
Akap4<em1Bbw> | MGI:7707395
Name: A kinase anchor protein 4; endonuclease-mediated mutation 1, Binbin Wang
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
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Strain
MGI:7767866 | C57BL/6J-Trim71<em1Ktka>
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Trim71/Trim71
Background: C57BL/6J-Trim71
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Trim71/Trim71<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
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Publication
7816809 | J:75287
First Author: Araki K
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase.
Volume: 92
Issue: 1
Pages: 160-4
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Publication
1314803 | -
First Author: Parent R
Year: 1992
Journal: J Bacteriol
Title: The chloramphenicol acetyltransferase gene of Tn2424: a new breed of cat.
Volume: 174
Issue: 9
Pages: 2891-7
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Protein Domain
IPR018372 | Chloramphenicol_AcTrfase_AS
Type: Active_site
Description: Chloramphenicol acetyltransferase (CAT) () []catalyzes the acetyl-CoA dependent acetylation of chloramphenicol (Cm), an antibiotic which inhibits prokaryotic peptidyltransferase activity. Acetylation of Cm by CAT inactivates the antibiotic. The pattern signature for this entry contains the histidine residue, located in the C-terminal section of the enzyme, that plays a central role in its catalytic mechanism.There is a second family of CAT [], evolutionary unrelated to the main family described above. These CAT belong to the bacterial hexapeptide-repeat containing-transferases family (see ).The crystal structure of the type III enzyme from Escherichia coli with chloramphenicol bound has been determined. CAT is a trimer of identical subunits (monomer Mr 25,000) and the trimeric structure is stabilised by a number of hydrogen bonds, some of which result in the extension of a β-sheet across the subunit interface. Chloramphenicol binds in a deep pocket located at the boundary between adjacent subunits of the trimer, such that the majority of residues forming the binding pocket belong to one subunit while the catalytically essential histidine belongs to the adjacent subunit. His195 is appropriately positioned to act as a general base catalyst in the reaction, and the required tautomeric stabilisation is provided by an unusual interaction with a main-chain carbonyl oxygen [].This signature pattern covers the region surrounding an active site histidine residue located in the C-terminal section of the enzyme; this residue plays a central role in its catalytic mechanism.
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Strain
MGI:3040071 | FVB-Tg(CAG-cat,-lacZ)1Brn/StmOrl
Attribute String: mutant strain, transgenic, coisogenic
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