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Search results 501 to 591 out of 591 for Cited2

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Type Details Score
Publication
First Author: Fame RM
Year: 2017
Journal: Cereb Cortex
Title: Subtype-Specific Genes that Characterize Subpopulations of Callosal Projection Neurons in Mouse Identify Molecularly Homologous Populations in Macaque Cortex.
Volume: 27
Issue: 3
Pages: 1817-1830
Publication
First Author: Bort R
Year: 2004
Journal: Development
Title: Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas.
Volume: 131
Issue: 4
Pages: 797-806
Publication
First Author: Lin W
Year: 2008
Journal: Dev Dyn
Title: Proper expression of the Gcn5 histone acetyltransferase is required for neural tube closure in mouse embryos.
Volume: 237
Issue: 4
Pages: 928-40
Publication
First Author: Heisig J
Year: 2012
Journal: PLoS Genet
Title: Target gene analysis by microarrays and chromatin immunoprecipitation identifies HEY proteins as highly redundant bHLH repressors.
Volume: 8
Issue: 5
Pages: e1002728
Publication
First Author: Ota MS
Year: 2004
Journal: Dev Dyn
Title: Twist is required for patterning the cranial nerves and maintaining the viability of mesodermal cells.
Volume: 230
Issue: 2
Pages: 216-28
Publication
First Author: Chassot AA
Year: 2012
Journal: Development
Title: WNT4 and RSPO1 together are required for cell proliferation in the early mouse gonad.
Volume: 139
Issue: 23
Pages: 4461-72
Publication    
First Author: López-Tello J
Year: 2019
Journal: Elife
Title: Fetal and trophoblast PI3K p110α have distinct roles in regulating resource supply to the growing fetus in mice.
Volume: 8
Publication  
First Author: Häfner R
Year: 2015
Journal: Mol Cell Endocrinol
Title: Fgfr2 is required for the expansion of the early adrenocortical primordium.
Volume: 413
Pages: 168-77
Publication
First Author: Bard-Chapeau EA
Year: 2014
Journal: PLoS One
Title: Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects.
Volume: 9
Issue: 2
Pages: e89397
Publication
First Author: Santos R
Year: 2016
Journal: PLoS Biol
Title: Conditional Creation and Rescue of Nipbl-Deficiency in Mice Reveals Multiple Determinants of Risk for Congenital Heart Defects.
Volume: 14
Issue: 9
Pages: e2000197
Publication
First Author: Takemoto M
Year: 2006
Journal: EMBO J
Title: Large-scale identification of genes implicated in kidney glomerulus development and function.
Volume: 25
Issue: 5
Pages: 1160-74
Publication
First Author: Kelleher AM
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Forkhead box a2 (FOXA2) is essential for uterine function and fertility.
Volume: 114
Issue: 6
Pages: E1018-E1026
Publication
First Author: Rajan S
Year: 2012
Journal: Physiol Genomics
Title: Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation.
Volume: 44
Issue: 2
Pages: 183-97
Publication
First Author: Richard AF
Year: 2011
Journal: Dev Biol
Title: Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression.
Volume: 359
Issue: 2
Pages: 303-20
Publication
First Author: Basta JM
Year: 2014
Journal: Development
Title: Sall1 balances self-renewal and differentiation of renal progenitor cells.
Volume: 141
Issue: 5
Pages: 1047-58
Publication  
First Author: Koutelou E
Year: 2019
Journal: Development
Title: USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta.
Volume: 146
Issue: 4
Publication    
First Author: Lee DR
Year: 2022
Journal: Elife
Title: Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain.
Volume: 11
Publication
First Author: Kawaguchi A
Year: 2008
Journal: Development
Title: Single-cell gene profiling defines differential progenitor subclasses in mammalian neurogenesis.
Volume: 135
Issue: 18
Pages: 3113-24
Publication      
First Author: MouseBookTM
Year: 2005
Journal: Unpublished
Title: Information obtained from MouseBookTM, Medical Research Council Mammalian Genetics Unit, Harwell, UK.
Publication
First Author: Mayer C
Year: 2018
Journal: Nature
Title: Developmental diversification of cortical inhibitory interneurons.
Volume: 555
Issue: 7697
Pages: 457-462
Publication
First Author: Oeschger FM
Year: 2012
Journal: Cereb Cortex
Title: Gene expression analysis of the embryonic subplate.
Volume: 22
Issue: 6
Pages: 1343-59
Publication  
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
Publication
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
Publication        
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
HT Experiment  
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: AlAbdi L
Year: 2018
Journal: J Biol Chem
Title: The transcription factor Vezf1 represses the expression of the antiangiogenic factor Cited2 in endothelial cells.
Volume: 293
Issue: 28
Pages: 11109-11118
Interaction Experiment
Description: Negative feedback regulation of NF-B action by CITED2 in the nucleus.
DO Term
HT Experiment  
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
GXD Expression  
Probe: MGI:7286085
Assay Type: RNA in situ
Annotation Date: 2022-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607512
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:7286311
Age: embryonic day 8.0
Note: Abnormal expression in a subset of Cited2 null embryos. Expression was either not detected or there was a left-sided bias.
Specimen Label: 2D
Detected: true
Specimen Num: 24
GXD Expression  
Probe: MGI:7286085
Assay Type: RNA in situ
Annotation Date: 2022-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607512
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:7286311
Age: embryonic day 8.0
Note: Abnormal expression in a subset of Cited2 null embryos. Expression was either not detected or there was a left-sided bias.
Specimen Label: 2F
Detected: true
Specimen Num: 26
GXD Expression  
Probe: MGI:7286085
Assay Type: RNA in situ
Annotation Date: 2022-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607512
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:7286311
Age: embryonic day 8.0
Note: Abnormal expression in a subset of Cited2 null embryos. Expression was either not detected or there was a left-sided bias.
Specimen Label: 2H
Detected: true
Specimen Num: 28
GXD Expression  
Probe: MGI:7286085
Assay Type: RNA in situ
Annotation Date: 2022-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603912
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:7286311
Age: embryonic day 8.0
Note: Abnormal expression in a subset of Cited2 null embryos. Expression was either not detected or there was a left-sided bias.
Specimen Label: 2C
Detected: true
Specimen Num: 23
GXD Expression  
Probe: MGI:7286085
Assay Type: RNA in situ
Annotation Date: 2022-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603912
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:7286311
Age: embryonic day 8.0
Note: Abnormal expression in a subset of Cited2 null embryos. Expression was either not detected or there was a left-sided bias.
Specimen Label: 2E
Detected: true
Specimen Num: 25
GXD Expression  
Probe: MGI:7286085
Assay Type: RNA in situ
Annotation Date: 2022-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603912
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:7286311
Age: embryonic day 8.0
Note: Abnormal expression in a subset of Cited2 null embryos. Expression was either not detected or there was a left-sided bias.
Specimen Label: 2G
Detected: true
Specimen Num: 27
Publication
First Author: Tien ES
Year: 2004
Journal: J Biol Chem
Title: Identification of the CREB-binding protein/p300-interacting protein CITED2 as a peroxisome proliferator-activated receptor alpha coregulator.
Volume: 279
Issue: 23
Pages: 24053-63
Publication
First Author: De Guzman RN
Year: 2004
Journal: J Biol Chem
Title: Interaction of the TAZ1 domain of the CREB-binding protein with the activation domain of CITED2: regulation by competition between intrinsically unstructured ligands for non-identical binding sites.
Volume: 279
Issue: 4
Pages: 3042-9
Protein Domain
Type: Homologous_superfamily
Description: TAZ (Transcription Adaptor putative Zinc finger) domains are zinc-containing domains found in the homologous transcriptional co-activators CREB-binding protein (CBP) and the P300. CBP and P300 are histone acetyltransferases () that catalyse the reversible acetylation of all four histones in nucleosomes, acting to regulate transcription via chromatin remodelling. These large nuclear proteins interact with numerous transcription factors and viral oncoproteins, including p53 tumour suppressor protein, E1A oncoprotein, MyoD, and GATA-1, and are involved in cell growth, differentiation and apoptosis []. Both CBP and P300 have two copies of the TAZ domain, one in the N-terminal region, the other in the C-terminal region. The TAZ1 domain of CBP and P300 forms a complex with CITED2 (CBP/P300-interacting transactivator with ED-rich tail), inhibiting the activity of the hypoxia inducible factor (HIF-1alpha) and thereby attenuating the cellular response to low tissue oxygen concentration []. Adaptation to hypoxia is mediated by transactivation of hypoxia-responsive genes by hypoxia-inducible factor-1 (HIF-1) in complex with the CBP and p300 transcriptional coactivators [].Proteins containing this domain also include a group of land-plant specific proteins, know as the BTB/POZ and TAZ domain-containing (BT) protein. The reports of their interaction with CUL3 are contradictory. They are multifunctional scaffold proteins essential for male and female gametophyte development []. The TAZ domain adopts an all-alpha fold with zinc-binding sites in the loops connecting the helices. The TAZ1 domain in P300 and the TAZ2 (CH3) domain in CBP have each been shown to have four amphipathic helices, organised by three zinc-binding clusters with HCCC-type coordination [, , ].
Publication
First Author: De Guzman RN
Year: 2000
Journal: J Mol Biol
Title: Solution structure of the TAZ2 (CH3) domain of the transcriptional adaptor protein CBP.
Volume: 303
Issue: 2
Pages: 243-53
Publication
First Author: Freedman SJ
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha.
Volume: 99
Issue: 8
Pages: 5367-72
Publication
First Author: Freedman SJ
Year: 2003
Journal: Nat Struct Biol
Title: Structural basis for negative regulation of hypoxia-inducible factor-1alpha by CITED2.
Volume: 10
Issue: 7
Pages: 504-12
Publication
First Author: De Guzman RN
Year: 2005
Journal: Biochemistry
Title: CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding.
Volume: 44
Issue: 2
Pages: 490-7
Publication
First Author: Robert HS
Year: 2009
Journal: Plant J
Title: BTB and TAZ domain scaffold proteins perform a crucial function in Arabidopsis development.
Volume: 58
Issue: 1
Pages: 109-21
Protein Domain
Type: Domain
Description: TAZ (Transcription Adaptor putative Zinc finger) domains are zinc-containing domains found in the homologous transcriptional co-activators CREB-binding protein (CBP) and the P300. CBP and P300 are histone acetyltransferases () that catalyse the reversible acetylation of all four histones in nucleosomes, acting to regulate transcription via chromatin remodelling. These large nuclear proteins interact with numerous transcription factors and viral oncoproteins, including p53 tumour suppressor protein, E1A oncoprotein, MyoD, and GATA-1, and are involved in cell growth, differentiation and apoptosis []. Both CBP and P300 have two copies of the TAZ domain, one in the N-terminal region, the other in the C-terminal region. The TAZ1 domain of CBP and P300 forms a complex with CITED2 (CBP/P300-interacting transactivator with ED-rich tail), inhibiting the activity of the hypoxia inducible factor (HIF-1alpha) and thereby attenuating the cellular response to low tissue oxygen concentration []. Adaptation to hypoxia is mediated by transactivation of hypoxia-responsive genes by hypoxia-inducible factor-1 (HIF-1) in complex with the CBP and p300 transcriptional coactivators [].Proteins containing this domain also include a group of land-plant specific proteins, know as the BTB/POZ and TAZ domain-containing (BT) protein. The reports of their interaction with CUL3 are contradictory. They are multifunctional scaffold proteins essential for male and female gametophyte development []. The TAZ domain adopts an all-alpha fold with zinc-binding sites in the loops connecting the helices. The TAZ1 domain in P300 and the TAZ2 (CH3) domain in CBP have each been shown to have four amphipathic helices, organised by three zinc-binding clusters with HCCC-type coordination [, , ].Zinc finger (Znf) domains are relatively small protein motifs which contain multiple finger-like protrusions that make tandem contacts with their target molecule. Some of these domains bind zinc, but many do not; instead binding other metals such as iron, or no metal at all. For example, some family members form salt bridges to stabilise the finger-like folds. They were first identified as a DNA-binding motif in transcription factor TFIIIA from Xenopus laevis (African clawed frog), however they are now recognised to bind DNA, RNA, protein and/or lipid substrates [, , , , ]. Their binding properties depend on the amino acid sequence of the finger domains and of the linker between fingers, as well as on the higher-order structures andthe number of fingers. Znf domains are often found in clusters, where fingers can have different binding specificities. There are many superfamilies of Znf motifs, varying in both sequence and structure. They display considerable versatility in binding modes, even between members of the same class (e.g. some bind DNA, others protein), suggesting that Znf motifs are stable scaffolds that have evolved specialised functions. For example, Znf-containing proteins function in gene transcription, translation, mRNA trafficking, cytoskeleton organisation, epithelial development, cell adhesion, protein folding, chromatin remodelling and zinc sensing, to name but a few []. Zinc-binding motifs are stable structures, and they rarely undergo conformational changes upon binding their target.
Protein
Organism: Mus musculus/domesticus
Length: 714  
Fragment?: false
Publication
First Author: Ponting CP
Year: 1996
Journal: Trends Biochem Sci
Title: ZZ and TAZ: new putative zinc fingers in dystrophin and other proteins.
Volume: 21
Issue: 1
Pages: 11-13
Protein
Organism: Mus musculus/domesticus
Length: 1589  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 2412  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2441  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2429  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 2403  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2441  
Fragment?: false
Publication
First Author: Matthews JM
Year: 2002
Journal: IUBMB Life
Title: Zinc fingers--folds for many occasions.
Volume: 54
Issue: 6
Pages: 351-5
Publication
First Author: Gamsjaeger R
Year: 2007
Journal: Trends Biochem Sci
Title: Sticky fingers: zinc-fingers as protein-recognition motifs.
Volume: 32
Issue: 2
Pages: 63-70
Publication
First Author: Hall TM
Year: 2005
Journal: Curr Opin Struct Biol
Title: Multiple modes of RNA recognition by zinc finger proteins.
Volume: 15
Issue: 3
Pages: 367-73
Publication
First Author: Brown RS
Year: 2005
Journal: Curr Opin Struct Biol
Title: Zinc finger proteins: getting a grip on RNA.
Volume: 15
Issue: 1
Pages: 94-8
Publication
First Author: Klug A
Year: 1999
Journal: J Mol Biol
Title: Zinc finger peptides for the regulation of gene expression.
Volume: 293
Issue: 2
Pages: 215-8
Publication
First Author: Laity JH
Year: 2001
Journal: Curr Opin Struct Biol
Title: Zinc finger proteins: new insights into structural and functional diversity.
Volume: 11
Issue: 1
Pages: 39-46