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Search results 501 to 600 out of 608 for Csf2

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Type Details Score
Publication
28202523 | J:242084
First Author: Valenti G
Year: 2017
Journal: Cancer Res
Title: Cancer Stem Cells Regulate Cancer-Associated Fibroblasts via Activation of Hedgehog Signaling in Mammary Gland Tumors.
Volume: 77
Issue: 8
Pages: 2134-2147
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Publication
19092943 | J:147182
First Author: Golonzhka O
Year: 2009
Journal: J Invest Dermatol
Title: Dual role of COUP-TF-interacting protein 2 in epidermal homeostasis and permeability barrier formation.
Volume: 129
Issue: 6
Pages: 1459-70
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Publication
28546511 | J:243650
First Author: Herriges MJ
Year: 2017
Journal: Genes Dev
Title: The NANCI-Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis.
Volume: 31
Issue: 9
Pages: 889-903
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Publication
8499630 | J:12563
First Author: McClanahan T
Year: 1993
Journal: Blood
Title: Hematopoietic growth factor receptor genes as markers of lineage commitment during in vitro development of hematopoietic cells.
Volume: 81
Issue: 11
Pages: 2903-15
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Publication
7507352 | J:16083
First Author: Taverne J
Year: 1993
Journal: Int J Exp Pathol
Title: Transgenic mice in the study of cytokine function.
Volume: 74
Issue: 6
Pages: 525-46
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Publication
8595891 | J:29693
First Author: Spicer AP
Year: 1995
Journal: Genomics
Title: The human and mouse receptors for hyaluronan-mediated motility, RHAMM, genes (HMMR) map to human chromosome 5q33.2-qter and mouse chromosome 11.
Volume: 30
Issue: 1
Pages: 115-7
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Publication
9070927 | J:37827
First Author: Watkins-Chow DE
Year: 1997
Journal: Genomics
Title: Genetic mapping of 21 genes on mouse chromosome 11 reveals disruptions in linkage conservation with human chromosome 5.
Volume: 40
Issue: 1
Pages: 114-22
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Publication
8903730 | J:31555
First Author: Stassen AP
Year: 1996
Journal: Mamm Genome
Title: Genetic composition of the recombinant congenic strains.
Volume: 7
Issue: 1
Pages: 55-8
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Publication
8043949 | J:18647
First Author: Ko MS
Year: 1994
Journal: Mamm Genome
Title: Genetic mapping of 40 cDNA clones on the mouse genome by PCR.
Volume: 5
Issue: 6
Pages: 349-55
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Publication
1794058 | J:459
First Author: Hearne CM
Year: 1991
Journal: Mamm Genome
Title: Additional microsatellite markers for mouse genome mapping.
Volume: 1
Issue: 4
Pages: 273-82
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Publication
8075499 | J:18140
First Author: Rowe LB
Year: 1994
Journal: Mamm Genome
Title: Maps from two interspecific backcross DNA panels available as a community genetic mapping resource.
Volume: 5
Issue: 5
Pages: 253-74
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Publication
22682244 | J:186161
First Author: Hu B
Year: 2012
Journal: Cell
Title: Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling.
Volume: 149
Issue: 6
Pages: 1207-20
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein Domain
IPR017546 | CRISPR-assoc_prot_Csf2
Type: Family
Description: This entry represents the Csf2 family of Cas proteins. Members of this family show up near CRISPR repeats in Acidithiobacillus ferrooxidans ATCC 23270, Azoarcus sp. (strain EbN1), and Rhodoferax ferrireducens (strain DSM 15236/ATCC BAA-621/T118). In the latter two species, the CRISPR/cas locus is found on a plasmid. This family is one of several characteristic of a type of cas gene cluster we designate Aferr after A. ferrooxidans, where it is both chromosomal and the only type of cas gene cluster found. The gene is designated csf2 (CRISPR/cas Subtype as in A. ferrooxidans protein 2), as it lies second closest to the repeats.The CRISPR-Cas system is a prokaryotic defense mechanism against foreign genetic elements. The key elements of this defense system are the Cas proteins and the CRISPR RNA. Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) are a family of DNA direct repeats separated by regularly sized non-repetitive spacer sequences that are found in most bacterial and archaeal genomes []. CRISPRs appear to provide acquired resistance against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).The defense reaction is divided into three stages. In the adaptation stage, the invader DNA is cleaved, and a piece of it is selected to be integrated as a new spacer into the CRISPR locus, where it is stored as an identity tag for future attacks by this invader. During the second stage (the expression stage), the CRISPR RNA (pre-crRNA) is transcribed and subsequently processed into the mature crRNAs. In the third stage (the interference stage), Cas proteins, together with crRNAs, identify and degrade the invader [, , ].The CRISPR-Cas systems have been sorted into three major classes. In CRISPR-Cas types I and III, the mature crRNA is generally generated by a member of the Cas6 protein family. Whereas in system III the Cas6 protein acts alone, in some class I systems it is part of a complex of Cas proteins known as Cascade (CRISPR-associated complex for antiviral defense). The Cas6 protein is an endoribonuclease necessary for crRNA production whereas the additional Cas proteins that form the Cascade complex are needed for crRNA stability [].
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Allele
Csf2<em4(CSF2)Smoc> | MGI:6446761
Name: colony stimulating factor 2 (granulocyte-macrophage); endonuclease-mediated mutation 4, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence, Null/knockout
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Allele
Csf2<em2Smoc> | MGI:7289168
Name: colony stimulating factor 2 (granulocyte-macrophage); endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Csf2<tm1(CSF2)Smoc> | MGI:7289170
Name: colony stimulating factor 2 (granulocyte-macrophage); targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Allele
Csf2<tm3(CSF2)Smoc> | MGI:7289171
Name: colony stimulating factor 2 (granulocyte-macrophage); targeted mutation 3, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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GO Term
GO:0038157 | granulocyte-macrophage colony-stimulating factor signaling pathway
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Allele
Idd4.3<NOD/ShiLtJ> | MGI:6850663
 
Name: insulin dependent diabetes susceptibility 4.3; NOD/ShiLtJ
Allele Type: QTL
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Strain
MGI:6428487 | C57BL/6JSmoc-Csf2<em2Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6354706 | C57BL/6JSmoc-Csf2<tm1(CSF2)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
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Allele
Il33<tm3(IL33)Smoc> | MGI:7290500
Name: interleukin 33; targeted mutation 3, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Csn1s1<em1(CSF2)Nrba> | MGI:7312048
Name: casein alpha s1; endonuclease-mediated mutation 1, Nariman R Battulin
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Csn1s1<em2(CSF2)Nrba> | MGI:7312049
Name: casein alpha s1; endonuclease-mediated mutation 2, Nariman R Battulin
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence, Null/knockout
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Strain
MGI:7788618 | C.B6JSmoc-Il3<tm3(IL3)Smoc> Csf2<tm3(CSF2)Smoc>/Smoc
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:6428973 | C57BL/6JSmoc-Il3<tm3(IL3)Smoc> Csf2<tm3(CSF2)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
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Allele
Del(11Irf1-D11Mit23)1Rub | MGI:3614966
 
Name: deletion, Chr 11, Edward M Rubin 1
Allele Type: Targeted
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Allele
Csf2/Il3<tm1.1(CSF2,IL3)Flv> | MGI:4887879
Name: colony stimulating factor 2 (granulocyte-macrophage); targeted mutation 1.1, Richard A Flavell
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Csf2/Il3<tm1.1(CSF2,IL3)Flv> | MGI:4887881
Name: interleukin 3; targeted mutation 1.1, Richard A Flavell
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:6850651 | B6.NOD-Idd5<NOD/ShiLtJ> Idd4.3<NOD/ShiLtJ>/Lith
Attribute String: congenic
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Strain
MGI:7718108 | C57BL/6JSmoc-Csf2<tm1(CSF2)Smoc> Csf1<tm2(CSF1)Smoc> Il3<tm1(IL3)Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain, targeted mutation
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Strain
MGI:6429827 | NOD.Cg-Csf2<em4(CSF2)Smoc> Prkdc<scid> Il2rg<em1Smoc>/Smoc
Attribute String: congenic, mutant strain, endonuclease-mediated mutation, spontaneous mutation
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Strain
MGI:7751774 | STOCK Csf2<tm3(CSF2)Smoc> Il3<tm3(IL3)Smoc> Prkdc<scid> Il2rg<em1Smoc>/Smoc
Attribute String: endonuclease-mediated mutation, mutant stock, spontaneous mutation, targeted mutation
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Strain
MGI:3615503 | STOCK Del(11Irf1-D11Mit23)1Rub/Mmnc
Attribute String: deletion, mutant stock, targeted mutation
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Strain
MGI:3615011 | 129/Sv-Del(11Irf1-D11Mit23)1Rub
Attribute String: mutant strain, targeted mutation, deletion, coisogenic
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Strain
MGI:7718109 | C57BL/6JSmoc-Sirpa<tm2(SIRPA)Smoc> Csf2<tm1(CSF2)Smoc> Cd47<em2(CD47)Smoc> Il3<tm1(IL3)Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
35568783 | J:326408
First Author: Smirnov AV
Year: 2022
Journal: Sci Rep
Title: Evaluation of the α-casein (CSN1S1) locus as a potential target for a site-specific transgene integration.
Volume: 12
Issue: 1
Pages: 7983
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Genotype
Genotype
Symbol: Del(11Irf1-D11Mit23)1Rub/Del(11Irf1-D11Mit23)1Rub
Background: 129/Sv-Del(11Irf1-D11Mit23)1Rub
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(11Irf1-D11Mit23)1Rub/+
Background: 129/Sv-Del(11Irf1-D11Mit23)1Rub
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Il2rg/Il2rg Csf2/Il3/Csf2/Il3 Rag2/Rag2
Background: involves: 129S4/SvJae * BALB/cAnNCr * BALB/cAnNTac
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Csf2/Il3/Csf2/Il3 Il2rg/Il2rg Rag2/Rag2
Background: involves: 129S4/SvJae * BALB/cAnNCr * BALB/cAnNTac
Zygosity: cx
Has Mutant Allele: true
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Strain
MGI:5555036 | C;129S4-Rag2<tm1.1Flv> Csf1<tm1(CSF1)Flv> Csf2/Il3<tm1.1(CSF2,IL3)Flv> Thpo<tm1.1(TPO)Flv> Il2rg<tm1.1Flv>/J
Attribute String: mutant stock, targeted mutation
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Publication
26982366 | J:237978
First Author: Kumar P
Year: 2016
Journal: Immunity
Title: Intestinal Interleukin-17 Receptor Signaling Mediates Reciprocal Control of the Gut Microbiota and Autoimmune Inflammation.
Volume: 44
Issue: 3
Pages: 659-671
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Publication
29958803 | J:278000
First Author: Wang Z
Year: 2018
Journal: Immunity
Title: Iron Drives T Helper Cell Pathogenicity by Promoting RNA-Binding Protein PCBP1-Mediated Proinflammatory Cytokine Production.
Volume: 49
Issue: 1
Pages: 80-92.e7
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Publication
32640223 | J:300234
First Author: Castro-Dopico T
Year: 2020
Journal: Cell Rep
Title: GM-CSF Calibrates Macrophage Defense and Wound Healing Programs during Intestinal Infection and Inflammation.
Volume: 32
Issue: 1
Pages: 107857
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Publication
26750311 | J:254659
First Author: Jain R
Year: 2016
Journal: Immunity
Title: Interleukin-23-Induced Transcription Factor Blimp-1 Promotes Pathogenicity of T Helper 17 Cells.
Volume: 44
Issue: 1
Pages: 131-142
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Publication
33079443 | J:303682
First Author: Biundo F
Year: 2021
Journal: Glia
Title: Microglial reduction of colony stimulating factor-1 receptor expression is sufficient to confer adult onset leukodystrophy.
Volume: 69
Issue: 3
Pages: 779-791
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Publication
33027513 | J:301357
     
First Author: Ito R
Year: 2020
Journal: Int Immunol
Title: Bovine β-lactoglobulin-induced passive systemic anaphylaxis model using humanized NOG hIL-3/hGM-CSF transgenic mice.
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Strain
MGI:5555040 | C;129S4-Rag2<tm1.1Flv> Csf1<tm1(CSF1)Flv> Csf2/Il3<tm1.1(CSF2,IL3)Flv> Thpo<tm1.1(TPO)Flv> Il2rg<tm1.1Flv> Tg(SIRPA)1Flv/J
Attribute String: targeted mutation, mutant stock, transgenic
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Strain
MGI:4887966 | C;129S4-Rag2<tm1.1Flv> Csf2/Il3<tm1.1(CSF2,IL3)Flv> Il2rg<tm1.1Flv>/J
Attribute String: mutant stock, targeted mutation
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Genotype
Genotype
Symbol: Csf1/Csf1 Il2rg/Il2rg Csf2/Il3/Csf2/Il3 Rag2/Rag2 Tg(SIRPA)1Flv/? Thpo/Thpo
Background: involves: 129S4/SvJae * BALB/cAnNTac
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Csf1/Csf1 Csf2/Il3/Csf2/Il3 Il2rg/Il2rg Rag2/Rag2 Thpo/Thpo
Background: involves: 129S4/SvJae * BALB/cAnNTac
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Csf1/Csf1 Il2rg/Il2rg Csf2/Il3/Csf2/Il3 Rag2/Rag2 Thpo/Thpo
Background: involves: 129S4/SvJae * BALB/cAnNTac
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Csf1/Csf1 Csf2/Il3/Csf2/Il3 Il2rg/Il2rg Rag2/Rag2 Tg(SIRPA)1Flv/? Thpo/Thpo
Background: involves: 129S4/SvJae * BALB/cAnNTac
Zygosity: cx
Has Mutant Allele: true
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Publication
17442114 | -
First Author: Kunin V
Year: 2007
Journal: Genome Biol
Title: Evolutionary conservation of sequence and secondary structures in CRISPR repeats.
Volume: 8
Issue: 4
Pages: R61
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Publication
17379808 | -
First Author: Barrangou R
Year: 2007
Journal: Science
Title: CRISPR provides acquired resistance against viruses in prokaryotes.
Volume: 315
Issue: 5819
Pages: 1709-12
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Publication
16545108 | -
 
First Author: Makarova KS
Year: 2006
Journal: Biol Direct
Title: A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action.
Volume: 1
Pages: 7
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Publication
21699496 | -
First Author: Howard JA
Year: 2011
Journal: Biochem J
Title: Helicase dissociation and annealing of RNA-DNA hybrids by Escherichia coli Cas3 protein.
Volume: 439
Issue: 1
Pages: 85-95
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Publication
24459147 | -
First Author: Brendel J
Year: 2014
Journal: J Biol Chem
Title: A complex of Cas proteins 5, 6, and 7 is required for the biogenesis and stability of clustered regularly interspaced short palindromic repeats (crispr)-derived rnas (crrnas) in Haloferax volcanii.
Volume: 289
Issue: 10
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Strain
MGI:3615513 | STOCK Del(11Irf1-D11Mit23)1Rub Tg(A94G6)1Rub/Mmucd
Attribute String: deletion, mutant stock, transgenic, targeted mutation
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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