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Search results 501 to 600 out of 644 for Cyp1a1

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Type Details Score
Publication
9224733 | J:41664
First Author: Ohgiya S
Year: 1997
Journal: Arch Biochem Biophys
Title: Establishment of a novel host, high-red yeast that stably expresses hamster NADPH-cytochrome P450 oxidoreductase: usefulness for examination of the function of mammalian cytochrome P450.
Volume: 343
Issue: 2
Pages: 215-24
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Publication
9934857 | J:52250
First Author: Brooks RA
Year: 1999
Journal: Carcinogenesis
Title: The mutagenicity of benzo[a]pyrene in mouse small intestine.
Volume: 20
Issue: 1
Pages: 109-14
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Publication
16085934 | J:102488
First Author: Pollenz RS
Year: 2005
Journal: J Biol Chem
Title: Redefining the role of the endogenous XAP2 and C-terminal hsp70-interacting protein on the endogenous Ah receptors expressed in mouse and rat cell lines.
Volume: 280
Issue: 39
Pages: 33346-56
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Publication
17023418 | J:117619
First Author: Sekine H
Year: 2006
Journal: J Biol Chem
Title: Unique and overlapping transcriptional roles of arylhydrocarbon receptor nuclear translocator (Arnt) and Arnt2 in xenobiotic and hypoxic responses.
Volume: 281
Issue: 49
Pages: 37507-16
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Publication
18096572 | J:133970
First Author: Dougherty EJ
Year: 2008
Journal: Toxicol Sci
Title: Analysis of Ah receptor-ARNT and Ah receptor-ARNT2 complexes in vitro and in cell culture.
Volume: 103
Issue: 1
Pages: 191-206
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Publication
17162532 | J:134715
First Author: Moto M
Year: 2006
Journal: Toxicol Pathol
Title: Gene expression analysis on the dicyclanil-induced hepatocellular tumors in mice.
Volume: 34
Issue: 6
Pages: 744-51
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Publication
19666105 | J:153426
First Author: Wang Z
Year: 2009
Journal: Free Radic Biol Med
Title: Overexpression of Cu/Zn-superoxide dismutase and/or catalase accelerates benzo(a)pyrene detoxification by upregulation of the aryl hydrocarbon receptor in mouse endothelial cells.
Volume: 47
Issue: 8
Pages: 1221-9
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Publication
20106948 | J:171791
First Author: DiNatale BC
Year: 2010
Journal: Toxicol Sci
Title: Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling.
Volume: 115
Issue: 1
Pages: 89-97
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Publication
22951721 | J:196484
First Author: Tigges J
Year: 2013
Journal: J Invest Dermatol
Title: Aryl hydrocarbon receptor repressor (AhRR) function revisited: repression of CYP1 activity in human skin fibroblasts is not related to AhRR expression.
Volume: 133
Issue: 1
Pages: 87-96
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Publication
19470599 | J:205245
First Author: Wihlén B
Year: 2009
Journal: Mol Cancer Res
Title: Estrogen receptor subtype- and promoter-specific modulation of aryl hydrocarbon receptor-dependent transcription.
Volume: 7
Issue: 6
Pages: 977-86
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Publication
23457121 | J:206900
First Author: Rignall B
Year: 2013
Journal: Toxicol Sci
Title: Biological and tumor-promoting effects of dioxin-like and non-dioxin-like polychlorinated biphenyls in mouse liver after single or combined treatment.
Volume: 133
Issue: 1
Pages: 29-41
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Publication
25305016 | J:218801
First Author: Solaimani P
Year: 2014
Journal: J Biol Chem
Title: SIN3A, generally regarded as a transcriptional repressor, is required for induction of gene transcription by the aryl hydrocarbon receptor.
Volume: 289
Issue: 48
Pages: 33655-62
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Publication
25602157 | J:220594
First Author: van den Bogaard EH
Year: 2015
Journal: J Invest Dermatol
Title: Genetic and pharmacological analysis identifies a physiological role for the AHR in epidermal differentiation.
Volume: 135
Issue: 5
Pages: 1320-1328
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Publication
26493931 | J:227919
First Author: Zhang F
Year: 2015
Journal: Toxicol Appl Pharmacol
Title: Effects of sexually dimorphic growth hormone secretory patterns on arachidonic acid metabolizing enzymes in rodent heart.
Volume: 289
Issue: 3
Pages: 495-506
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Publication
19299563 | J:338739
First Author: Flaveny CA
Year: 2009
Journal: Mol Pharmacol
Title: Ligand selectivity and gene regulation by the human aryl hydrocarbon receptor in transgenic mice.
Volume: 75
Issue: 6
Pages: 1412-20
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Publication
37272852 | J:341970
First Author: Dong F
Year: 2023
Journal: FASEB J
Title: Complex chemical signals dictate Ah receptor activation through the gut-lung axis.
Volume: 37
Issue: 7
Pages: e23010
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Publication
22895187 | J:186765
First Author: Koo BK
Year: 2012
Journal: Nature
Title: Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.
Volume: 488
Issue: 7413
Pages: 665-9
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Publication
27207656 | J:232782
First Author: Wang H
Year: 2016
Journal: Carcinogenesis
Title: Obesity promotes PhIP-induced small intestinal carcinogenesis in hCYP1A-db/db mice: involvement of mutations and DNA hypermethylation of Apc.
Volume: 37
Issue: 7
Pages: 723-730
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Publication
22884366 | J:196014
First Author: Radulescu S
Year: 2012
Journal: Cell Rep
Title: Luminal iron levels govern intestinal tumorigenesis after Apc loss in vivo.
Volume: 2
Issue: 2
Pages: 270-82
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Publication
25307863 | J:232543
First Author: BĂĽller NV
Year: 2015
Journal: Gastroenterology
Title: Stromal Indian hedgehog signaling is required for intestinal adenoma formation in mice.
Volume: 148
Issue: 1
Pages: 170-180.e6
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Publication
20736363 | J:165592
First Author: Cole AM
Year: 2010
Journal: Cancer Res
Title: Cyclin D2-cyclin-dependent kinase 4/6 is required for efficient proliferation and tumorigenesis following Apc loss.
Volume: 70
Issue: 20
Pages: 8149-58
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Publication
30552232 | J:272062
First Author: Young MA
Year: 2019
Journal: Mol Cancer Res
Title: Epigenetic Regulation of Dlg1, via Kaiso, Alters Mitotic Spindle Polarity and Promotes Intestinal Tumorigenesis.
Volume: 17
Issue: 3
Pages: 686-696
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Publication
15480419 | J:94711
First Author: Reed KR
Year: 2004
Journal: Oncogene
Title: PPARdelta status and Apc-mediated tumourigenesis in the mouse intestine.
Volume: 23
Issue: 55
Pages: 8992-6
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Publication
24662053 | J:215358
First Author: Cecchini MJ
Year: 2014
Journal: Mol Cell Biol
Title: A retinoblastoma allele that is mutated at its common E2F interaction site inhibits cell proliferation in gene-targeted mice.
Volume: 34
Issue: 11
Pages: 2029-45
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Publication
20016602 | J:155799
First Author: Chong JL
Year: 2009
Journal: Nature
Title: E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells.
Volume: 462
Issue: 7275
Pages: 930-4
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Publication
26192440 | J:227295
First Author: Liu H
Year: 2015
Journal: Nat Cell Biol
Title: Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles.
Volume: 17
Issue: 8
Pages: 1036-48
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Publication
30119997 | J:277045
First Author: Metidji A
Year: 2018
Journal: Immunity
Title: The Environmental Sensor AHR Protects from Inflammatory Damage by Maintaining Intestinal Stem Cell Homeostasis and Barrier Integrity.
Volume: 49
Issue: 2
Pages: 353-362.e5
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Publication
22119784 | J:178925
First Author: Itzkovitz S
Year: 2011
Journal: Nat Cell Biol
Title: Single-molecule transcript counting of stem-cell markers in the mouse intestine.
Volume: 14
Issue: 1
Pages: 106-14
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Publication
25500896 | J:275009
 
First Author: Simmini S
Year: 2014
Journal: Nat Commun
Title: Transformation of intestinal stem cells into gastric stem cells on loss of transcription factor Cdx2.
Volume: 5
Pages: 5728
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Publication
27585866 | J:237929
First Author: Chiacchiera F
Year: 2016
Journal: EMBO J
Title: PRC2 preserves intestinal progenitors and restricts secretory lineage commitment.
Volume: 35
Issue: 21
Pages: 2301-2314
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Publication
26192438 | J:227297
First Author: Lu WY
Year: 2015
Journal: Nat Cell Biol
Title: Hepatic progenitor cells of biliary origin with liver repopulation capacity.
Volume: 17
Issue: 8
Pages: 971-983
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Publication
24685131 | J:211824
First Author: Song JH
Year: 2014
Journal: Cell Rep
Title: The APC network regulates the removal of mutated cells from colonic crypts.
Volume: 7
Issue: 1
Pages: 94-103
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Publication
24258210 | J:210358
First Author: Kerr GE
Year: 2014
Journal: Biol Reprod
Title: Regulated Wnt/beta-catenin signaling sustains adult spermatogenesis in mice.
Volume: 90
Issue: 1
Pages: 3
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Publication
24037525 | J:213044
First Author: Greenow KR
Year: 2014
Journal: Oncogene
Title: Wnt-driven intestinal tumourigenesis is suppressed by Chk1 deficiency but enhanced by conditional haploinsufficiency.
Volume: 33
Issue: 31
Pages: 4089-96
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Publication
16959882 | J:113749
First Author: Sansom OJ
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo.
Volume: 103
Issue: 38
Pages: 14122-7
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Publication
18644872 | J:140355
First Author: Phesse TJ
Year: 2008
Journal: Mol Cell Biol
Title: Deficiency of Mbd2 attenuates Wnt signaling.
Volume: 28
Issue: 19
Pages: 6094-103
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Publication
26956214 | J:236502
 
First Author: van der Heijden M
Year: 2016
Journal: Nat Commun
Title: Bcl-2 is a critical mediator of intestinal transformation.
Volume: 7
Pages: 10916
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Publication
21283818 | J:169565
First Author: Shorning BY
Year: 2011
Journal: PLoS One
Title: Lkb1 and Pten synergise to suppress mTOR-mediated tumorigenesis and epithelial-mesenchymal transition in the mouse bladder.
Volume: 6
Issue: 1
Pages: e16209
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Publication
15131783 | J:92092
First Author: Ireland H
Year: 2004
Journal: Gastroenterology
Title: Inducible Cre-mediated control of gene expression in the murine gastrointestinal tract: effect of loss of beta-catenin.
Volume: 126
Issue: 5
Pages: 1236-46
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Publication
16954380 | J:114673
First Author: Muncan V
Year: 2006
Journal: Mol Cell Biol
Title: Rapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-Myc.
Volume: 26
Issue: 22
Pages: 8418-26
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Publication
21480232 | J:171973
First Author: Cheng CW
Year: 2011
Journal: J Pathol
Title: Activation of mutated K-ras in donor endometrial epithelium and stroma promotes lesion growth in an intact immunocompetent murine model of endometriosis.
Volume: 224
Issue: 2
Pages: 261-9
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Publication
32690888 | J:291426
First Author: Sato T
Year: 2020
Journal: Nat Cell Biol
Title: Regulated IFN signalling preserves the stemness of intestinal stem cells by restricting differentiation into secretory-cell lineages.
Volume: 22
Issue: 8
Pages: 919-926
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Publication
18778245 | J:147474
First Author: Finn RD
Year: 2009
Journal: Biochem J
Title: Unsaturated fatty acid regulation of cytochrome P450 expression via a CAR-dependent pathway.
Volume: 417
Issue: 1
Pages: 43-54
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Publication
20569471 | J:196052
 
First Author: McCutcheon SC
Year: 2010
Journal: BMC Biol
Title: Characterization of a heat resistant beta-glucosidase as a new reporter in cells and mice.
Volume: 8
Pages: 89
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Publication
21878906 | J:205646
 
First Author: Muncan V
Year: 2011
Journal: Nat Commun
Title: Blimp1 regulates the transition of neonatal to adult intestinal epithelium.
Volume: 2
Pages: 452
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Publication
27157990 | J:233829
First Author: Cohran V
Year: 2016
Journal: Am J Pathol
Title: Epithelial PIK3R1 (p85) and TP53 Regulate Survivin Expression during Adaptation to Ileocecal Resection.
Volume: 186
Issue: 7
Pages: 1837-46
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Publication
22821983 | J:323380
First Author: Doupé DP
Year: 2012
Journal: Science
Title: A single progenitor population switches behavior to maintain and repair esophageal epithelium.
Volume: 337
Issue: 6098
Pages: 1091-3
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Publication
19269367 | J:148715
First Author: van der Flier LG
Year: 2009
Journal: Cell
Title: Transcription factor achaete scute-like 2 controls intestinal stem cell fate.
Volume: 136
Issue: 5
Pages: 903-12
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Publication
26174178 | J:313143
First Author: Gonneaud A
Year: 2016
Journal: J Cell Physiol
Title: Distinct Roles for Intestinal Epithelial Cell-Specific Hdac1 and Hdac2 in the Regulation of Murine Intestinal Homeostasis.
Volume: 231
Issue: 2
Pages: 436-48
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Publication
25892522 | J:263295
First Author: Flanagan DJ
Year: 2015
Journal: Stem Cell Reports
Title: Frizzled7 functions as a Wnt receptor in intestinal epithelial Lgr5(+) stem cells.
Volume: 4
Issue: 5
Pages: 759-67
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Publication
29439001 | J:263054
First Author: Balbinot C
Year: 2018
Journal: J Exp Med
Title: The Cdx2 homeobox gene suppresses intestinal tumorigenesis through non-cell-autonomous mechanisms.
Volume: 215
Issue: 3
Pages: 911-926
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Publication
25759216 | J:221041
First Author: Horvay K
Year: 2015
Journal: EMBO J
Title: Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium.
Volume: 34
Issue: 10
Pages: 1319-35
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Publication
23922304 | J:204013
First Author: Holik AZ
Year: 2013
Journal: Stem Cells
Title: Brg1 is required for stem cell maintenance in the murine intestinal epithelium in a tissue-specific manner.
Volume: 31
Issue: 11
Pages: 2457-66
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Publication
25512559 | J:217374
First Author: Rai TS
Year: 2014
Journal: Genes Dev
Title: HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia.
Volume: 28
Issue: 24
Pages: 2712-25
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Allele
Cyp1a<tm1Dwn> | MGI:3721229
Name: cytochrome P450, family 1, subfamily a cluster; targeted mutation 1, Daniel W Nebert
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:3721792 | B6.129-Cyp1a<tm1Dwn>
Attribute String: targeted mutation, mutant strain, congenic, deletion
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Genotype
Genotype
Symbol: Cyp1a/Cyp1a
Background: B6.129-Cyp1a
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Apc/Apc<+> Pten/Pten Tg(Cyp1a1-cre/ERT)1Dwi/?
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Apc/Apc Pten/Pten Tg(Cyp1a1-cre/ERT)1Dwi/?
Background: involves: 129S4/SvJae * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Publication
8634152 | J:32093
First Author: Vasiliou V
Year: 1996
Journal: DNA Cell Biol
Title: Mouse microsomal Class 3 aldehyde dehydrogenase: AHD3 cDNA sequence, inducibility by dioxin and clofibrate, and genetic mapping.
Volume: 15
Issue: 3
Pages: 235-45
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Publication
8195121 | J:18333
First Author: Savas U
Year: 1994
Journal: J Biol Chem
Title: Mouse cytochrome P-450EF, representative of a new 1B subfamily of cytochrome P-450s. Cloning, sequence determination, and tissue expression.
Volume: 269
Issue: 21
Pages: 14905-11
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Publication
10677587 | J:60274
First Author: Vasiliou V
Year: 2000
Journal: Biochem Pharmacol
Title: Comparison of oxidative stress response parameters in newborn mouse liver versus simian virus 40 (SV40)-transformed hepatocyte cell lines.
Volume: 59
Issue: 6
Pages: 703-12
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Publication
17376491 | J:123179
First Author: Knaapen AM
Year: 2007
Journal: Mutat Res
Title: The environmental carcinogen benzo[a]pyrene induces expression of monocyte-chemoattractant protein-1 in vascular tissue: a possible role in atherogenesis.
Volume: 621
Issue: 1-2
Pages: 31-41
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Publication
27559173 | J:235213
First Author: Ziegler N
Year: 2016
Journal: J Neurosci
Title: β-Catenin Is Required for Endothelial Cyp1b1 Regulation Influencing Metabolic Barrier Function.
Volume: 36
Issue: 34
Pages: 8921-35
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Publication
37113990 | J:345810
 
First Author: Wu M
Year: 2023
Journal: Front Genet
Title: Nrf2(-/-) regulated lung DNA demethylation and CYP2E1 DNA methylation under PM(2.5) exposure.
Volume: 14
Pages: 1144903
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Publication
19056912 | J:163971
First Author: Zhang QY
Year: 2009
Journal: Drug Metab Dispos
Title: An intestinal epithelium-specific cytochrome P450 (P450) reductase-knockout mouse model: direct evidence for a role of intestinal p450s in first-pass clearance of oral nifedipine.
Volume: 37
Issue: 3
Pages: 651-7
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Publication
9377560 | J:43453
First Author: Alexander DL
Year: 1997
Journal: Cancer Res
Title: Ah receptor regulation of CYP1B1 expression in primary mouse embryo-derived cells.
Volume: 57
Issue: 20
Pages: 4498-506
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Publication
10605936 | J:58872
First Author: Nebert DW
Year: 2000
Journal: Biochem Pharmacol
Title: Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis.
Volume: 59
Issue: 1
Pages: 65-85
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Publication
10828274 | J:62981
First Author: Gressani KM
Year: 2000
Journal: Toxicol Sci
Title: Prenatal toxicity and lack of carcinogenicity of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) following transplacental exposure.
Volume: 55
Issue: 2
Pages: 407-14
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Publication
1312672 | J:1544
First Author: Carrier F
Year: 1992
Journal: Mol Cell Biol
Title: Dioxin-dependent activation of murine Cyp1a-1 gene transcription requires protein kinase C-dependent phosphorylation.
Volume: 12
Issue: 4
Pages: 1856-63
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Publication
7508708 | J:16642
First Author: Nemoto N
Year: 1994
Journal: Arch Biochem Biophys
Title: Elevated expression of the Cyp1a2 gene in the presence of nicotinamide by adult mouse hepatocytes in primary culture.
Volume: 308
Issue: 1
Pages: 292-8
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Publication
8006463 | J:18879
First Author: Jugert FK
Year: 1994
Journal: J Invest Dermatol
Title: Multiple cytochrome P450 isozymes in murine skin: induction of P450 1A, 2B, 2E, and 3A by dexamethasone.
Volume: 102
Issue: 6
Pages: 970-5
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Publication
7744798 | J:25184
First Author: Bhattacharyya KK
Year: 1995
Journal: J Biol Chem
Title: Identification of a rat adrenal cytochrome P450 active in polycyclic hydrocarbon metabolism as rat CYP1B1. Demonstration of a unique tissue-specific pattern of hormonal and aryl hydrocarbon receptor-linked regulation.
Volume: 270
Issue: 19
Pages: 11595-602
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Publication
9067559 | J:39409
First Author: Witschi H
Year: 1997
Journal: Carcinogenesis
Title: The carcinogenicity of environmental tobacco smoke.
Volume: 18
Issue: 3
Pages: 575-86
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Publication
9233375 | J:42406
First Author: Ryu DY
Year: 1997
Journal: Chem Biol Interact
Title: Regulation of hepatic CYP1A isozymes by piperonyl butoxide and acenaphthylene in the mouse.
Volume: 105
Issue: 1
Pages: 53-63
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Publication
9434738 | J:45020
First Author: Mori T
Year: 1997
Journal: Arch Biochem Biophys
Title: Regulation of CYP1A and CYP3A mRNAs by ascorbic acid in guinea pigs.
Volume: 348
Issue: 2
Pages: 268-77
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Publication
9637800 | J:49681
First Author: Maier A
Year: 1998
Journal: Environ Health Perspect
Title: Aromatic hydrocarbon receptor polymorphism: development of new methods to correlate genotype with phenotype.
Volume: 106
Issue: 7
Pages: 421-6
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Publication
12584184 | J:78489
First Author: Buters J
Year: 2003
Journal: Carcinogenesis
Title: CYP1B1 determines susceptibility to low doses of 7,12-dimethylbenz[a]anthracene-induced ovarian cancers in mice: correlation of CYP1B1-mediated DNA adducts with carcinogenicity.
Volume: 24
Issue: 2
Pages: 327-34
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Publication
15183014 | J:102095
First Author: Filbrandt CR
Year: 2004
Journal: Neurotoxicology
Title: Presence and functional activity of the aryl hydrocarbon receptor in isolated murine cerebral vascular endothelial cells and astrocytes.
Volume: 25
Issue: 4
Pages: 605-16
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Publication
16929009 | J:113290
First Author: Choi SS
Year: 2006
Journal: Toxicol Sci
Title: In utero exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin induces amphiregulin gene expression in the developing mouse ureter.
Volume: 94
Issue: 1
Pages: 163-74
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Publication
19749160 | J:154312
First Author: Peters J
Year: 2009
Journal: Am J Physiol Heart Circ Physiol
Title: Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism.
Volume: 297
Issue: 5
Pages: H1845-52
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Publication
21929726 | J:192073
First Author: Avadhani NG
Year: 2011
Journal: FEBS J
Title: Bimodal targeting of cytochrome P450s to endoplasmic reticulum and mitochondria: the concept of chimeric signals.
Volume: 278
Issue: 22
Pages: 4218-29
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Publication
24519526 | J:213688
First Author: Kurita H
Year: 2014
Journal: Toxicol Sci
Title: The Ah receptor recruits IKKα to its target binding motifs to phosphorylate serine-10 in histone H3 required for transcriptional activation.
Volume: 139
Issue: 1
Pages: 121-32
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Publication
21535883 | J:303606
 
First Author: Alberts R
Year: 2011
Journal: Respir Res
Title: Genome-wide analysis of the mouse lung transcriptome reveals novel molecular gene interaction networks and cell-specific expression signatures.
Volume: 12
Pages: 61
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Publication
29603746 | J:266665
First Author: May S
Year: 2018
Journal: J Pathol
Title: Mbd2 enables tumourigenesis within the intestine while preventing tumour-promoting inflammation.
Volume: 245
Issue: 3
Pages: 270-282
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Publication
22922255 | J:190744
First Author: Jamieson T
Year: 2012
Journal: J Clin Invest
Title: Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis.
Volume: 122
Issue: 9
Pages: 3127-44
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Publication
22057237 | J:178629
First Author: March HN
Year: 2011
Journal: Nat Genet
Title: Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis.
Volume: 43
Issue: 12
Pages: 1202-9
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Publication
22318232 | J:182751
First Author: Ueo T
Year: 2012
Journal: Development
Title: The role of Hes genes in intestinal development, homeostasis and tumor formation.
Volume: 139
Issue: 6
Pages: 1071-82
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Publication
24264992 | J:205193
First Author: Vermeulen L
Year: 2013
Journal: Science
Title: Defining stem cell dynamics in models of intestinal tumor initiation.
Volume: 342
Issue: 6161
Pages: 995-8
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Publication
26679840 | J:227691
First Author: Cheung EC
Year: 2016
Journal: Genes Dev
Title: Opposing effects of TIGAR- and RAC1-derived ROS on Wnt-driven proliferation in the mouse intestine.
Volume: 30
Issue: 1
Pages: 52-63
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Publication
30576387 | J:269445
First Author: O'Driscoll CA
Year: 2018
Journal: PLoS One
Title: Polycyclic aromatic hydrocarbons (PAHs) present in ambient urban dust drive proinflammatory T cell and dendritic cell responses via the aryl hydrocarbon receptor (AHR) in vitro.
Volume: 13
Issue: 12
Pages: e0209690
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Publication
30858608 | J:285667
First Author: Liko D
Year: 2019
Journal: Cell Death Differ
Title: Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas.
Volume: 26
Issue: 12
Pages: 2535-2550
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Publication
22190642 | J:179732
First Author: Stringer EJ
Year: 2012
Journal: Development
Title: Cdx2 determines the fate of postnatal intestinal endoderm.
Volume: 139
Issue: 3
Pages: 465-74
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Publication
19033191 | J:142249
First Author: Reed KR
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver.
Volume: 105
Issue: 48
Pages: 18919-23
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Publication
20708588 | J:163669
First Author: Ashton GH
Year: 2010
Journal: Dev Cell
Title: Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling.
Volume: 19
Issue: 2
Pages: 259-69
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Publication
24735923 | J:210629
First Author: Valeri N
Year: 2014
Journal: Cancer Cell
Title: MicroRNA-135b promotes cancer progression by acting as a downstream effector of oncogenic pathways in colon cancer.
Volume: 25
Issue: 4
Pages: 469-83
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Publication
23335179 | J:195059
First Author: Parry L
Year: 2013
Journal: Stem Cells
Title: Evidence for a crucial role of paneth cells in mediating the intestinal response to injury.
Volume: 31
Issue: 4
Pages: 776-85
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Publication
24583641 | J:229501
First Author: Phesse TJ
Year: 2014
Journal: Cell Death Differ
Title: Endogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo.
Volume: 21
Issue: 6
Pages: 956-66
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Publication
20887898 | J:164644
First Author: Snippert HJ
Year: 2010
Journal: Cell
Title: Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells.
Volume: 143
Issue: 1
Pages: 134-44
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Strain
MGI:3721805 | STOCK Cyp1a<tm1Dwn> Tg(CYP1A1,CYP1A2)1Dwn/J
Attribute String: targeted mutation, transgenic, mutant stock, deletion
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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