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Search results 501 to 600 out of 935 for Dbh

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Type Details Score
Publication
35103284 | J:321979
 
First Author: Kurz J
Year: 2022
Journal: Development
Title: Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter.
Volume: 149
Issue: 4
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Publication
29688375 | J:250512
   
First Author: Li J
Year: 2018
Journal: Database (Oxford)
Title: CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.
Volume: 2018
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Publication
9371744 | J:44483
First Author: Brady KP
Year: 1997
Journal: Genome Res
Title: Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis.
Volume: 7
Issue: 11
Pages: 1085-93
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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Publication
- | J:342601
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Strain
MGI:5770777 | B6.129S7(FVB)-Dbh<em2.1(flpo)Rray>/Mmucd
Attribute String: mutant strain, congenic, endonuclease-mediated mutation
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GXD Expression
GXD Expression
Probe: MGI:7608292
Assay Type: RNA in situ
Annotation Date: 2024-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1756320
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7608312
Age: embryonic day 12.5
Image: 3B Rnf220 E2
Note: Expression overlapping with Dbh expression.
Specimen Label: 3B Rnf220 E2
Detected: true
Specimen Num: 2
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Allele
Dbh<em2.1(flpo)Rray> | MGI:5770774
Name: dopamine beta hydroxylase; endonuclease-mediated mutation 2.1, Russell Ray
Allele Type: Endonuclease-mediated
Attribute String: Recombinase
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GXD Expression
GXD Expression
Probe: MGI:7608292
Assay Type: RNA in situ
Annotation Date: 2024-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1629017
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7608312
Age: embryonic day 10.5
Image: 3A Rnf220 E2
Note: Expression in dorsal rhombomere 1, overlapping with Dbh expression.
Specimen Label: 3A Rnf220 E2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7608063
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1629017
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7608327
Age: embryonic day 10.5
Image: 1A Dbh/Phox2a
Note: Expression in dorsal rhombomere 1, colocalized with Dbh and Phox2b expression..
Specimen Label: 1A Dbh/Phox2a
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7608064
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1629017
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7608329
Age: embryonic day 10.5
Image: 1A Dbh/Phox2b
Note: Expression in dorsal rhombomere 1, colocalized with Dbh and Phox2a expression..
Specimen Label: 1A Dbh/Phox2b
Detected: true
Specimen Num: 1
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Allele
Dbh<tm1(cre)Sath> | MGI:6850023
Name: dopamine beta hydroxylase; targeted mutation 1, Steven A Thomas
Allele Type: Targeted
Attribute String: Recombinase
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Allele
Dbh<tm2(Th)Rpa> | MGI:1928960
 
Name: dopamine beta hydroxylase; targeted mutation 2, Richard D Palmiter
Allele Type: Targeted
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Allele
Dbh<tm1(flpo)Pjen> | MGI:5495939
Name: dopamine beta hydroxylase; targeted mutation 1, Patricia Jensen
Allele Type: Targeted
Attribute String: Recombinase
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Allele
Tg(DBH-TH)4-4Koba | MGI:7280908
Name: transgene insertion 4-4, Kazuto Kobayashi
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Dbh/Dbh<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
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Allele
Tg(Chrm4-tTA)1Kftnk | MGI:7520789
Name: transgene insertion 1, Kenji Tanaka
Allele Type: Transgenic
Attribute String: Transactivator
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Allele
Tg(Dbh-tTA)1Kftnk | MGI:7520787
Name: transgene insertion 1, Kenji Tanaka
Allele Type: Transgenic
Attribute String: Transactivator
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Allele
Tg(DBH-PTS)41Csic | MGI:7513828
Name: transgene insertion 41, Chiho Sumi-Ichinose
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Dbh/Dbh
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dbh/Dbh<+>
Background: involves: 129S7/SvEvBrd * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dbh/Dbh
Background: involves: 129S7/SvEvBrd * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Publication
15848803 | -
First Author: Alkema MJ
Year: 2005
Journal: Neuron
Title: Tyramine Functions independently of octopamine in the Caenorhabditis elegans nervous system.
Volume: 46
Issue: 2
Pages: 247-60
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Publication
14623230 | -
First Author: Monastirioti M
Year: 2003
Journal: Dev Biol
Title: Distinct octopamine cell population residing in the CNS abdominal ganglion controls ovulation in Drosophila melanogaster.
Volume: 264
Issue: 1
Pages: 38-49
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Publication
14978721 | -
First Author: Saraswati S
Year: 2004
Journal: J Neurobiol
Title: Tyramine and octopamine have opposite effects on the locomotion of Drosophila larvae.
Volume: 58
Issue: 4
Pages: 425-41
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Publication
11857564 | -
First Author: Kim CH
Year: 2002
Journal: Am J Med Genet
Title: Mutations in the dopamine beta-hydroxylase gene are associated with human norepinephrine deficiency.
Volume: 108
Issue: 2
Pages: 140-7
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Publication
20301647 | -
       
First Author: Robertson D
Year: 1993
Title: Dopamine Beta-Hydroxylase Deficiency
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Protein Domain
IPR028460 | Tbh/DBH
Type: Family
Description: This entry includes tyramine beta-hydroxylases from invertebrates and dopamine beta-hydroxylases from mammals. Tyramine beta-hydroxylase (TBH) converts tyramine into octopamine, a neurotransmitter involved in pharyngeal pumping and egg laying in Caenorhabditis elegans []and in ovulation and locomotion in Drosophila [, , ]. It is evolutionarily related and remarkably similar to mammalian dopamine beta-hydroxylase [].Dopamine beta-hydroxylases (DBH) converts dopamine to noradrenaline (norepinephrine), a key neurotransmitter of the central and peripheral nervous systems [, ]. DBH is a copper-containing oxygenase consisting of four identical subunits. Mutations in DBH gene cause the dopamine beta-hydroxylase deficiency (DBH deficiency), which is characterised by profound deficits in autonomic and cardiovascular function [].
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Publication
21634003 | J:180731
First Author: Stubbusch J
Year: 2011
Journal: Genesis
Title: Generation of the tamoxifen-inducible DBH-Cre transgenic mouse line DBH-CT.
Volume: 49
Issue: 12
Pages: 935-41
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Allele
Tg(Dbh-icre)1Gsc | MGI:4355551
Name: transgene insertion 1, Gunther Schutz
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Dbh-EGFP)FI99Gsat | MGI:4846982
Name: transgene insertion FI99, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Dbh-cre)KH212Gsat | MGI:4846983
Name: transgene insertion KH212, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Dbh-cre)KH210Gsat | MGI:5435477
Name: transgene insertion KH210, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Recombinase
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Strain
MGI:6147124 | STOCK Tg(Chrm4-tTA)Kftnk/KftnkRbrc
Attribute String: mutant stock, transgenic
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Strain
MGI:6147121 | STOCK Tg(Dbh-tTA)1Kftnk
Attribute String: mutant stock, transgenic
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Strain
MGI:6145632 | C57BL/6J-Tg(DBH-PTS)41Csic/CsicRbrc
Attribute String: mutant strain, coisogenic, transgenic
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Publication
8656284 | J:33417
First Author: Monastirioti M
Year: 1996
Journal: J Neurosci
Title: Characterization of Drosophila tyramine beta-hydroxylase gene and isolation of mutant flies lacking octopamine.
Volume: 16
Issue: 12
Pages: 3900-11
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Publication
6998654 | -
First Author: Rush RA
Year: 1980
Journal: Crit Rev Clin Lab Sci
Title: Dopamine beta-hydroxylase in health and disease.
Volume: 12
Issue: 3
Pages: 241-77
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Publication
34231420 | J:313747
First Author: Torres H
Year: 2021
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Sympathetic innervation of the mouse kidney and liver arising from prevertebral ganglia.
Volume: 321
Issue: 3
Pages: R328-R337
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Publication
2295597 | -
First Author: Robertson JG
Year: 1990
Journal: J Biol Chem
Title: Primary amino acid sequence of bovine dopamine beta-hydroxylase.
Volume: 265
Issue: 2
Pages: 1029-35
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Protein Domain
IPR000945 | DBH-like
Type: Family
Description: This family represents Dopamine beta-hydroxylase (DBH) and related enzymes, including tyramine beta-hydroxylase, MOXD1 homologue 1/2 and DBH-like monooxygenase protein 1/2 [].DBH, also known as Dopamine beta-hydroxylase, is a class of ascorbate-dependent enzymes from the catecholamine biosynthetic pathway that requires copper as a cofactor and uses ascorbate as an electron donor. DBH catalyses the conversion of dopamine to the neurotransmitter norepinephrine:3,4-dihydroxyphenethylamine+ ascorbate + O2= noradrenaline + dehydroascorbate + H2ODBH exists in both soluble (in chromaffin granules) and membrane bound forms. The protein functions as a homotetramer [, ].This entry includes monooxigenases found in metazoans, plants and fungi.
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Strain
MGI:3845923 | B6;129-Dbh<tm2(Th)Rpa> Th<tm1Rpa>/J
Attribute String: targeted mutation, mutant stock
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Publication
25367503 | J:324572
First Author: Hagino Y
Year: 2015
Journal: Neuropsychopharmacology
Title: Involvement of cholinergic system in hyperactivity in dopamine-deficient mice.
Volume: 40
Issue: 5
Pages: 1141-50
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Publication
29037208 | J:324625
First Author: Fujita M
Year: 2017
Journal: Mol Brain
Title: Light/dark phase-dependent spontaneous activity is maintained in dopamine-deficient mice.
Volume: 10
Issue: 1
Pages: 49
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Publication
32948232 | J:324571
First Author: Fujita M
Year: 2020
Journal: Mol Brain
Title: Increase in excitability of hippocampal neurons during novelty-induced hyperlocomotion in dopamine-deficient mice.
Volume: 13
Issue: 1
Pages: 126
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Publication
9822156 | J:51145
First Author: Nishii K
Year: 1998
Journal: J Neurosci Res
Title: Motor and learning dysfunction during postnatal development in mice defective in dopamine neuronal transmission.
Volume: 54
Issue: 4
Pages: 450-64
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Allele
Tg(DBH-RET*M918T)CH7720Rpk | MGI:3767822
Name: transgene insertion CH7720, Raj P Kapur
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(DBH-RET*M918T)CH7194Rpk | MGI:3767823
Name: transgene insertion CH7194, Raj P Kapur
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(DBH-RET*M918T)CH7214Rpk | MGI:3767825
Name: transgene insertion CH7214, Raj P Kapur
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(DBH-PTS)6Csic | MGI:3813870
Name: transgene insertion 6, Chiho Sumi-Ichinose
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Publication
23977333 | J:206424
First Author: Chmielarz P
Year: 2013
Journal: PLoS One
Title: Inactivation of glucocorticoid receptor in noradrenergic system influences anxiety- and depressive-like behavior in mice.
Volume: 8
Issue: 8
Pages: e72632
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Publication
31227310 | J:284541
First Author: Zerbi V
Year: 2019
Journal: Neuron
Title: Rapid Reconfiguration of the Functional Connectome after Chemogenetic Locus Coeruleus Activation.
Volume: 103
Issue: 4
Pages: 702-718.e5
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Allele
Tg(Dbh-cre/ERT2)198.1Hroh | MGI:4821735
Name: transgene insertion 198.1, Hermann Rohrer
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Strain
MGI:6376528 | STOCK Tg(Dbh-cre/ERT2)198.1Hroh/J
Attribute String: transgenic, mutant stock
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Strain
MGI:5003572 | STOCK Tg(Dbh-EGFP)FI99Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Strain
MGI:5004197 | STOCK Tg(Dbh-cre)KH212Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Strain
MGI:5491214 | B6.FVB(Cg)-Tg(Dbh-cre)KH212Gsat/Mmucd
Attribute String: congenic, transgenic, mutant strain
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Publication
35273081 | J:348891
First Author: Dvorkin R
Year: 2022
Journal: J Neurosci
Title: Precise and Pervasive Phasic Bursting in Locus Coeruleus during Maternal Behavior in Mice.
Volume: 42
Issue: 14
Pages: 2986-2999
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Publication
31315047 | J:298893
First Author: Li S
Year: 2019
Journal: Cell Rep
Title: Conversion of Astrocytes and Fibroblasts into Functional Noradrenergic Neurons.
Volume: 28
Issue: 3
Pages: 682-697.e7
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Publication
37037362 | J:355760
 
First Author: Abe C
Year: 2023
Journal: Brain Behav Immun
Title: Repeated activation of C1 neurons in medulla oblongata decreases anti-inflammatory effect via the hypofunction of the adrenal gland adrenergic response.
Volume: 111
Pages: 138-150
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Publication
26560463 | J:285975
First Author: Stornetta RL
Year: 2016
Journal: Brain Struct Funct
Title: Afferent and efferent connections of C1 cells with spinal cord or hypothalamic projections in mice.
Volume: 221
Issue: 8
Pages: 4027-4044
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Publication
28711601 | J:351941
 
First Author: Rukhadze I
Year: 2017
Journal: Respir Physiol Neurobiol
Title: Catecholaminergic A1/C1 neurons contribute to the maintenance of upper airway muscle tone but may not participate in NREM sleep-related depression of these muscles.
Volume: 244
Pages: 41-50
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Publication
34648731 | J:349556
First Author: Osorio-Forero A
Year: 2021
Journal: Curr Biol
Title: Noradrenergic circuit control of non-REM sleep substates.
Volume: 31
Issue: 22
Pages: 5009-5023.e7
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Publication
33071759 | J:308226
 
First Author: Sun P
Year: 2020
Journal: Front Neural Circuits
Title: Sex-Related Differential Whole-Brain Input Atlas of Locus Coeruleus Noradrenaline Neurons.
Volume: 14
Pages: 53
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Publication
39587312 | J:361476
First Author: Osorio-Forero A
Year: 2025
Journal: Nat Neurosci
Title: Infraslow noradrenergic locus coeruleus activity fluctuations are gatekeepers of the NREM-REM sleep cycle.
Volume: 28
Issue: 1
Pages: 84-96
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Publication
23407970 | J:248619
First Author: Abbott SB
Year: 2013
Journal: J Neurosci
Title: Selective optogenetic activation of rostral ventrolateral medullary catecholaminergic neurons produces cardiorespiratory stimulation in conscious mice.
Volume: 33
Issue: 7
Pages: 3164-77
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Publication
38142024 | J:350219
 
First Author: Herlihy R
Year: 2024
Journal: Respir Physiol Neurobiol
Title: Chronic intermittent hypoxia attenuates noradrenergic innervation of hypoglossal motor nucleus.
Volume: 321
Pages: 104206
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Publication
33196030 | J:349761
First Author: Nomura S
Year: 2020
Journal: iScience
Title: Combined Optogenetic Approaches Reveal Quantitative Dynamics of Endogenous Noradrenergic Transmission in the Brain.
Volume: 23
Issue: 11
Pages: 101710
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Publication
37200091 | J:338553
 
First Author: Chen CH
Year: 2023
Journal: JCI Insight
Title: Gastric vagal afferent signaling to the basolateral amygdala mediates anxiety-like behaviors in experimental colitis mice.
Volume: 8
Issue: 12
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Strain
MGI:5435798 | STOCK Tg(Dbh-cre)KH210Gsat/Mmucd
Attribute String: transgenic, mutant stock
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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