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Search results 501 to 592 out of 592 for E2f4

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Type Details Score
Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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HT Experiment
E-GEOD-13753 | Transcription profiling of mouse placentas from wild-type and Rb -/- knock-out mice and embryonic day 11.5 placentas from wild-type and Rb -/-;E2f4 -/- double knock-outs reveals E2F4 cooperates with pRB in the development of extra-embryonic, not embryonic, tissues
Series Id: GSE13753
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Interaction Experiment
Rousseau V (2023)
Description: Trim33 masks a non-transcriptional function of E2f4 in replication fork progression.
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Allele
E2f4<em1Smoc> | MGI:7289429
Name: E2F transcription factor 4; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Interaction Experiment
Ferrer-Vicens I (2014)
Description: In vivo genome-wide binding of Id2 to E2F4 target genes as part of a reversible program in mice liver.
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Publication
17531812 | -
First Author: Litovchick L
Year: 2007
Journal: Mol Cell
Title: Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence.
Volume: 26
Issue: 4
Pages: 539-51
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Publication
37612308 | -
First Author: Rousseau V
Year: 2023
Journal: Nat Commun
Title: Trim33 masks a non-transcriptional function of E2f4 in replication fork progression.
Volume: 14
Issue: 1
Pages: 5143
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Publication
24573694 | -
First Author: Ferrer-Vicens I
Year: 2014
Journal: Cell Mol Life Sci
Title: In vivo genome-wide binding of Id2 to E2F4 target genes as part of a reversible program in mice liver.
Volume: 71
Issue: 18
Pages: 3583-97
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HT Experiment
E-GEOD-76926 | RNA-seq transcriptonal profiling in partial hepatectomy liver tissues in Arid1a WT and liver specific KO mice
Series Id: GSE76926
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
16730350 | J:111333
First Author: Sandoval R
Year: 2006
Journal: Exp Cell Res
Title: A mutant allele of BARA/LIN-9 rescues the cdk4-/- phenotype by releasing the repression on E2F-regulated genes.
Volume: 312
Issue: 13
Pages: 2465-75
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Publication
17075059 | -
First Author: Harrison MM
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Some C. elegans class B synthetic multivulva proteins encode a conserved LIN-35 Rb-containing complex distinct from a NuRD-like complex.
Volume: 103
Issue: 45
Pages: 16782-7
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Publication
15538385 | -
First Author: Gagrica S
Year: 2004
Journal: EMBO J
Title: Inhibition of oncogenic transformation by mammalian Lin-9, a pRB-associated protein.
Volume: 23
Issue: 23
Pages: 4627-38
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Publication
1524653 | -
First Author: Presswood R
Year: 1992
Journal: Int J Prosthodont
Title: A philosophy of dental practice.
Volume: 5
Issue: 3
Pages: 291
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Publication
23667535 | -
First Author: Esterlechner J
Year: 2013
Journal: PLoS One
Title: LIN9, a subunit of the DREAM complex, regulates mitotic gene expression and proliferation of embryonic stem cells.
Volume: 8
Issue: 5
Pages: e62882
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Protein Domain
IPR010561 | LIN-9/ALY1
Type: Family
Description: This entry represents protein LIN-9/ALWAYS EARLY (LIN-9/ALY). LIN-9 from Caenorhabditis elegans is a homologue of the Drosophila always early (ALY) protein, which functions as a repressor of cell cycle regulated genes [, ].LIN-9 is a component of the evolutionary conserved DREAM (MuvB/DRM) complex, which represses transcription []. DREAM complex undergoes a cell cycle dependent switch of subunits. DREAM core bindsto the E2F4 transcription factor and to the RBL2 (p130) in quiescent cells, while associates with the transcription factor B-MYB in the S-phase []. In humans, LIN-9 acts as a tumor suppressor and plays a role in the expression of genes required for the G1/S transition [, ]. In pluripotent embryonic stem cells (ESC), LIN-9 plays an important role for proliferation and genome stability by activating genes with important functions in mitosis and cytokinesis [].In Arabidopsis thaliana, ALY is expressed ubiquitously in vegetative and reproductive tissues [].
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Publication
15769944 | J:96750
First Author: Liu DX
Year: 2005
Journal: Genes Dev
Title: Regulation of neuron survival and death by p130 and associated chromatin modifiers.
Volume: 19
Issue: 6
Pages: 719-32
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Publication
18995834 | J:143178
First Author: van Oevelen C
Year: 2008
Journal: Mol Cell
Title: A role for mammalian Sin3 in permanent gene silencing.
Volume: 32
Issue: 3
Pages: 359-70
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Publication
22174740 | -
First Author: Rodriguez-Jato S
Year: 2011
Journal: PLoS One
Title: Drosophila melanogaster dHCF interacts with both PcG and TrxG epigenetic regulators.
Volume: 6
Issue: 12
Pages: e27479
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Protein
A0A0A6YWF7
Organism: Mus musculus/domesticus
Length: 272  
Fragment?: false
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Protein
A0A0A6YXQ9
Organism: Mus musculus/domesticus
Length: 73  
Fragment?: true
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Publication
15246533 | -
First Author: Bhatt AM
Year: 2004
Journal: Gene
Title: Gene structure and molecular analysis of Arabidopsis thaliana ALWAYS EARLY homologs.
Volume: 336
Issue: 2
Pages: 219-29
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Publication
10629049 | -
First Author: Mahajan SS
Year: 2000
Journal: Mol Cell Biol
Title: Mutations in host cell factor 1 separate its role in cell proliferation from recruitment of VP16 and LZIP.
Volume: 20
Issue: 3
Pages: 919-28
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Publication
14532282 | J:87274
First Author: Luciano RL
Year: 2003
Journal: J Biol Chem
Title: HCF-1 functions as a coactivator for the zinc finger protein Krox20.
Volume: 278
Issue: 51
Pages: 51116-24
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Publication
10675337 | -
First Author: Vogel JL
Year: 2000
Journal: EMBO J
Title: The novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABP.
Volume: 19
Issue: 4
Pages: 683-90
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Publication
12244100 | -
First Author: Piluso D
Year: 2002
Journal: J Biol Chem
Title: Host cell factor-1 interacts with and antagonizes transactivation by the cell cycle regulatory factor Miz-1.
Volume: 277
Issue: 48
Pages: 46799-808
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Publication
10920196 | -
First Author: Vogel JL
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Autocatalytic proteolysis of the transcription factor-coactivator C1 (HCF): a potential role for proteolytic regulation of coactivator function.
Volume: 97
Issue: 17
Pages: 9425-30
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Publication
16624878 | -
First Author: Vogel JL
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Site-specific proteolysis of the transcriptional coactivator HCF-1 can regulate its interaction with protein cofactors.
Volume: 103
Issue: 18
Pages: 6817-22
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Publication
31049581 | -
First Author: Gudkova D
Year: 2019
Journal: Nucleic Acids Res
Title: HCF-2 inhibits cell proliferation and activates differentiation-gene expression programs.
Volume: 47
Issue: 11
Pages: 5792-5808
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Publication
12609738 | -
First Author: Izeta A
Year: 2003
Journal: Gene
Title: Primary structure and compartmentalization of Drosophila melanogaster host cell factor.
Volume: 305
Issue: 2
Pages: 175-83
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Publication
2568582 | -
First Author: Sabina RL
Year: 1989
Journal: Mol Cell Biol
Title: Expression of three stage-specific transcripts of AMP deaminase during myogenesis.
Volume: 9
Issue: 5
Pages: 2244-6
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Protein Domain
IPR043536 | HCF1/2
Type: Family
Description: This entry includes Host cell factor 1 (HCF1) and Host cell factor 2 (HCF2) from humans. They contain an N-terminal kelch domain and a C-terminal FnIII domain. However, HCF2 is smaller than HCF-1, lacking the complete central region including the HCF1 specific repeats and as a result is not subject to proteolytic processing []. This entry also includes their Drosophila melanogaster homologue, dHCF, which is involved in both activation and repression of transcription during fly development []. Host cell factor homologue hcf-1 from C. elegans controls the cell cycle through mitotic histone phosphorylation modulation and negatively regulates responses to environmental stresses [].HCF1 is associated with the activation and repression of gene expression. It is brought to specific promoters by association with DNA-sequence-specific transcription factors such as Sp1, GABP, YY1, Ronin/THAP11, and E2F1 and E2F4 []. HCFC1 recruits and is a part of several different complexes, including the SET1 histone methyltransferase complex (transcription activation), the SIN3 histone deacetylase complex (transcription repression) [], the THAP1/THAP3-HCFC1-OGT complex (required for the regulation of the transcriptional activity of RRM1) [], and the NSL complex (acetylation of nucleosomal histone H4) [].HCF2 is involved in activation of differentiation and morphogenesis gene expression programs, and in parallel in inhibition of cellular growth and metabolism [].
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Protein Domain
IPR037854 | HCF1
Type: Family
Description: Host cell factor 1 (HCFC1) is associated with the activation and repression of gene expression. It is brought to specific promoters by association with DNA-sequence-specific transcription factors such as Sp1, GABP, YY1, Ronin/THAP11, and E2F1 and E2F4 []. HCFC1 recruits and is a part of several different complexes, including the SET1 histone methyltransferase complex (transcription activation), the SIN3 histone deacetylase complex (transcription repression) [], the THAP1/THAP3-HCFC1-OGT complex (required for the regulation of the transcriptional activity of RRM1) [], and the NSL complex (acetylation of nucleosomal histone H4) []. This entry includes mammalian HCFC1 and the Drosophila homologue, dHCF. They undergo a process of proteolytic maturation to produce a heterodimeric complex of HCF-N and HCF-C subunits, by different enzymes, O-GlcNAc transferase and taspase1, respectively [, ]. They share a Kelch domain, regions biased for basic (Basic) or acidic (Acidic) amino acids, fibronectin type 3 repeats, and a nuclear localization signal [].During human herpes simplex virus infection, HCFC1 forms a multiprotein-DNA complex enabling transcription of the virus's early genes []. It is also a co-activator of EGR2/Krox20 []and the GA-binding protein GABP2 [], and represses ZBTB17/Miz-1 [].
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Publication
20713602 | J:163915
First Author: Scimè A
Year: 2010
Journal: J Cell Biol
Title: Oxidative status of muscle is determined by p107 regulation of PGC-1alpha.
Volume: 190
Issue: 4
Pages: 651-62
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Publication
33073500 | J:349651
First Author: Tiwari SK
Year: 2020
Journal: EMBO Rep
Title: Zika virus depletes neural stem cells and evades selective autophagy by suppressing the Fanconi anemia protein FANCC.
Volume: 21
Issue: 12
Pages: e49183
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Publication
12724423 | J:83303
First Author: Scheijen B
Year: 2003
Journal: Mol Cell Biol
Title: Constitutive E2F1 overexpression delays endochondral bone formation by inhibiting chondrocyte differentiation.
Volume: 23
Issue: 10
Pages: 3656-68
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Publication
11429786 | J:70633
First Author: Wang D
Year: 2001
Journal: Mol Carcinog
Title: Deregulated expression of DP1 induces epidermal proliferation and enhances skin carcinogenesis.
Volume: 31
Issue: 2
Pages: 90-100
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Publication
38491202 | J:348295
First Author: Young MJ
Year: 2024
Journal: Cell Death Differ
Title: USP24-i-101 targeting of USP24 activates autophagy to inhibit drug resistance acquired during cancer therapy.
Volume: 31
Issue: 5
Pages: 574-591
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Publication
27991932 | J:243159
First Author: Wang SA
Year: 2017
Journal: Oncogene
Title: EGF-mediated inhibition of ubiquitin-specific peptidase 24 expression has a crucial role in tumorigenesis.
Volume: 36
Issue: 21
Pages: 2930-2945
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Publication
30877126 | J:274880
 
First Author: Lu H
Year: 2019
Journal: Development
Title: Mcidas mutant mice reveal a two-step process for the specification and differentiation of multiciliated cells in mammals.
Volume: 146
Issue: 6
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Publication
12198120 | J:79877
First Author: Kobayashi M
Year: 2002
Journal: J Biol Chem
Title: Ectopic expression of necdin induces differentiation of mouse neuroblastoma cells.
Volume: 277
Issue: 44
Pages: 42128-35
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Publication
11751403 | J:73359
First Author: Gadd M
Year: 2001
Journal: Cancer Res
Title: Regulation of cyclin D1 and p16(INK4A) is critical for growth arrest during mammary involution.
Volume: 61
Issue: 24
Pages: 8811-9
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Publication
10779352 | J:65132
First Author: Leone G
Year: 2000
Journal: Mol Cell Biol
Title: Identification of a novel E2F3 product suggests a mechanism for determining specificity of repression by Rb proteins.
Volume: 20
Issue: 10
Pages: 3626-32
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Publication
12077144 | J:78775
First Author: Blais A
Year: 2002
Journal: J Biol Chem
Title: Regulation of the human cyclin-dependent kinase inhibitor p18INK4c by the transcription factors E2F1 and Sp1.
Volume: 277
Issue: 35
Pages: 31679-93
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Publication
12771133 | J:84885
First Author: Caretti G
Year: 2003
Journal: J Biol Chem
Title: Dynamic recruitment of NF-Y and histone acetyltransferases on cell-cycle promoters.
Volume: 278
Issue: 33
Pages: 30435-40
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Publication
16216419 | J:108560
First Author: Feo F
Year: 2006
Journal: Biochim Biophys Acta
Title: Hepatocellular carcinoma as a complex polygenic disease. Interpretive analysis of recent developments on genetic predisposition.
Volume: 1765
Issue: 2
Pages: 126-47
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Publication
19619530 | J:154490
First Author: Sandoval R
Year: 2009
Journal: Exp Cell Res
Title: Deletion of the p107/p130-binding domain of Mip130/LIN-9 bypasses the requirement for CDK4 activity for the dissociation of Mip130/LIN-9 from p107/p130-E2F4 complex.
Volume: 315
Issue: 17
Pages: 2914-20
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Publication
24071582 | J:211415
First Author: Fischer M
Year: 2014
Journal: Nucleic Acids Res
Title: Polo-like kinase 4 transcription is activated via CRE and NRF1 elements, repressed by DREAM through CDE/CHR sites and deregulated by HPV E7 protein.
Volume: 42
Issue: 1
Pages: 163-80
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Publication
31278282 | J:297007
First Author: Singh BN
Year: 2019
Journal: Sci Rep
Title: Etv2 transcriptionally regulates Yes1 and promotes cell proliferation during embryogenesis.
Volume: 9
Issue: 1
Pages: 9736
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Publication
12670868 | -
First Author: Wysocka J
Year: 2003
Journal: Genes Dev
Title: Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1.
Volume: 17
Issue: 7
Pages: 896-911
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Protein
Q8C735
Organism: Mus musculus/domesticus
Length: 542  
Fragment?: false
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Protein
A0A0A6YWD3
Organism: Mus musculus/domesticus
Length: 518  
Fragment?: true
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Protein
A0A0A6YVZ7
Organism: Mus musculus/domesticus
Length: 558  
Fragment?: false
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Publication
16086373 | J:107086
First Author: Wilker E
Year: 2005
Journal: Mol Carcinog
Title: Role of PI3K/Akt signaling in insulin-like growth factor-1 (IGF-1) skin tumor promotion.
Volume: 44
Issue: 2
Pages: 137-45
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Publication
31068677 | J:302983
First Author: Wildung M
Year: 2019
Journal: Cell Death Differ
Title: Transcription factor TAp73 and microRNA-449 complement each other to support multiciliogenesis.
Volume: 26
Issue: 12
Pages: 2740-2757
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Publication
16738312 | J:115056
First Author: Agromayor M
Year: 2006
Journal: Mol Cell Biol
Title: Visualizing dynamic E2F-mediated repression in vivo.
Volume: 26
Issue: 12
Pages: 4448-61
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Publication
8657141 | J:125251
First Author: Karlseder J
Year: 1996
Journal: Mol Cell Biol
Title: Interaction of Sp1 with the growth- and cell cycle-regulated transcription factor E2F.
Volume: 16
Issue: 4
Pages: 1659-67
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Publication
20200153 | -
First Author: Mazars R
Year: 2010
Journal: J Biol Chem
Title: The THAP-zinc finger protein THAP1 associates with coactivator HCF-1 and O-GlcNAc transferase: a link between DYT6 and DYT3 dystonias.
Volume: 285
Issue: 18
Pages: 13364-71
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Protein
Q3USQ6
Organism: Mus musculus/domesticus
Length: 209  
Fragment?: true
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Protein
F6SJS2
Organism: Mus musculus/domesticus
Length: 612  
Fragment?: true
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Publication
20018852 | -
First Author: Cai Y
Year: 2010
Journal: J Biol Chem
Title: Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex.
Volume: 285
Issue: 7
Pages: 4268-72
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Protein
Q61191
Organism: Mus musculus/domesticus
Length: 2045  
Fragment?: false
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Protein
B1AUX2
Organism: Mus musculus/domesticus
Length: 2090  
Fragment?: false
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Protein
F6T088
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: true
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Protein
F6T0G2
Organism: Mus musculus/domesticus
Length: 145  
Fragment?: true
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Protein
A0AUN4
Organism: Mus musculus/domesticus
Length: 365  
Fragment?: true
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Protein
Q9D968
Organism: Mus musculus/domesticus
Length: 722  
Fragment?: false
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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