| Type |
Details |
Score |
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
386
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
389
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
377
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
220
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Allele |
| Name: |
ectodysplasin-A; tabby 25 Harwell |
| Allele Type: |
Radiation induced |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
ectodysplasin-A; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Maeda K |
| Year: |
2010 |
| Journal: |
J Biol Chem |
| Title: |
GANP-mediated recruitment of activation-induced cytidine deaminase to cell nuclei and to immunoglobulin variable region DNA. |
| Volume: |
285 |
| Issue: |
31 |
| Pages: |
23945-53 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Madaule P |
| Year: |
1998 |
| Journal: |
Nature |
| Title: |
Role of citron kinase as a target of the small GTPase Rho in cytokinesis. |
| Volume: |
394 |
| Issue: |
6692 |
| Pages: |
491-4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Madaule P |
| Year: |
2000 |
| Journal: |
Microsc Res Tech |
| Title: |
Citron, a Rho target that affects contractility during cytokinesis. |
| Volume: |
49 |
| Issue: |
2 |
| Pages: |
123-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Morita C |
| Year: |
1994 |
| Journal: |
Zentralbl Veterinarmed B |
| Title: |
Origin of lymphocytic-choriomeningitis-virus-bearing mice in Japan. |
| Volume: |
41 |
| Issue: |
4 |
| Pages: |
291-3 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee D |
| Year: |
2016 |
| Journal: |
J Clin Invest |
| Title: |
Endogenous transmembrane protein UT2 inhibits pSTAT3 and suppresses hematological malignancy. |
| Volume: |
126 |
| Issue: |
4 |
| Pages: |
1300-10 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ohtani K |
| Year: |
2002 |
| Journal: |
GenBank Submission |
| Title: |
Mus musculus CL-P1 mRNA for collectin placenta 1, complete cds |
|
|
| Pages: |
AB078434 |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE6952 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mutoh H |
| Year: |
2002 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Conversion of gastric mucosa to intestinal metaplasia in Cdx2-expressing transgenic mice. |
| Volume: |
294 |
| Issue: |
2 |
| Pages: |
470-9 |
|
•
•
•
•
•
|
| Allele |
| Name: |
ectodysplasin-A; tabby Jackson |
| Allele Type: |
Spontaneous |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
ectodysplasin-A; tabby 4 Jackson |
| Allele Type: |
Spontaneous |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
ectodysplasin-A; tabby 29 Harwell |
| Allele Type: |
Radiation induced |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
ectodysplasin-A; tabby 30 Harwell |
| Allele Type: |
Radiation induced |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
ectodysplasin-A; tabby 32 Harwell |
| Allele Type: |
Radiation induced |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
ectodysplasin-A; tabby 33 Harwell |
| Allele Type: |
Spontaneous |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
ectodysplasin-A; tabby 9 Jackson |
| Allele Type: |
Spontaneous |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
ectodysplasin-A; tabby 40 Harwell |
| Allele Type: |
Chemically induced (ENU) |
|
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
deletion, radiation induced mutation, mutant stock |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kawai T |
| Year: |
2002 |
| Journal: |
Biosci Biotechnol Biochem |
| Title: |
Molecular cloning of mouse collectin liver 1. |
| Volume: |
66 |
| Issue: |
10 |
| Pages: |
2134-45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ohtani K |
| Year: |
2001 |
| Journal: |
J Biol Chem |
| Title: |
The membrane-type collectin CL-P1 is a scavenger receptor on vascular endothelial cells. |
| Volume: |
276 |
| Issue: |
47 |
| Pages: |
44222-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
de Oliveira EA |
| Year: |
2012 |
| Journal: |
PLoS One |
| Title: |
Structural and functional characterization of the protein kinase Mps1 in Arabidopsis thaliana. |
| Volume: |
7 |
| Issue: |
9 |
| Pages: |
e45707 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sun C |
| Year: |
2015 |
| Journal: |
Am J Physiol Gastrointest Liver Physiol |
| Title: |
Expression of Reg family genes in the gastrointestinal tract of mice treated with indomethacin. |
| Volume: |
308 |
| Issue: |
9 |
| Pages: |
G736-44 |
|
•
•
•
•
•
|
| Allele |
| Name: |
ectodysplasin-A; tabby 23 Harwell |
| Allele Type: |
Chemically induced (ENU) |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
ectodysplasin-A; tabby 26 Harwell |
| Allele Type: |
Spontaneous |
|
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
radiation induced mutation, mutant stock |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant stock, radiation induced mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
radiation induced mutation, mutant stock |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant stock, spontaneous mutation |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/Eda<+> |
| Background: |
involves: LDJ/LeJ |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/Eda<+> |
| Background: |
involves: 129 |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/? |
| Background: |
involves: 129 |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/Eda<+> |
| Background: |
involves: CBA/J |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/? |
| Background: |
involves: CBA/J |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/Eda |
| Background: |
involves: CBA/J |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/? |
| Background: |
Not Specified |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/Eda<+> |
| Background: |
Not Specified |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/? |
| Background: |
Not Specified |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/Eda<+> |
| Background: |
Not Specified |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/Eda<+> |
| Background: |
Not Specified |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/? |
| Background: |
Not Specified |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/? |
| Background: |
Not Specified |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/Eda<+> |
| Background: |
Not Specified |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/? |
| Background: |
involves: 129 |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Allele |
| Name: |
sex linked lethal 2; sex-linked lethal 2 |
| Allele Type: |
Spontaneous |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Muro AF |
| Year: |
2008 |
| Journal: |
Am J Respir Crit Care Med |
| Title: |
An essential role for fibronectin extra type III domain A in pulmonary fibrosis. |
| Volume: |
177 |
| Issue: |
6 |
| Pages: |
638-45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Roberts AL |
| Year: |
2020 |
| Journal: |
Sci Rep |
| Title: |
Fibronectin extra domain A (FN-EDA) elevates intraocular pressure through Toll-like receptor 4 signaling. |
| Volume: |
10 |
| Issue: |
1 |
| Pages: |
9815 |
|
•
•
•
•
•
|
| Allele |
| Name: |
ectodysplasin-A; tabby 10 Jackson |
| Allele Type: |
Spontaneous |
|
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
chemically induced mutation, mutant stock |
|
•
•
•
•
•
|
| Allele |
| Name: |
ectodysplasin-A; tabby 43 Harwell |
| Allele Type: |
Spontaneous |
| Attribute String: |
Not Specified |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/Eda<+> |
| Background: |
involves: BALB/c * C3H/HeN |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/? |
| Background: |
C3H101H-Eda/H |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/Eda<+> |
| Background: |
C3H101H-Eda/H |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/Eda |
| Background: |
C3H101H-Eda/H |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Walters MJ |
| Year: |
2008 |
| Journal: |
Bioorg Med Chem |
| Title: |
Characterization and crystal structure of Escherichia coli KDPGal aldolase. |
| Volume: |
16 |
| Issue: |
2 |
| Pages: |
710-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nishihara H |
| Year: |
1969 |
| Journal: |
Biochim Biophys Acta |
| Title: |
A stereospecific 2-keto-4-hydroxyglutarate aldolase from Escherichia coli. |
| Volume: |
185 |
| Issue: |
1 |
| Pages: |
255-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Murray EL |
| Year: |
2005 |
| Journal: |
J Bacteriol |
| Title: |
Multiple regulators control expression of the Entner-Doudoroff aldolase (Eda) of Escherichia coli. |
| Volume: |
187 |
| Issue: |
3 |
| Pages: |
991-1000 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
4-Hydroxy-2-oxoglutarate aldolase () (KHG-aldolase) catalyzes the interconversion of 4-hydroxy-2-oxoglutarate into pyruvate and glyoxylate. Phospho-2-dehydro-3-deoxygluconate aldolase () (KDPG-aldolase) catalyzes the interconversion of 6-phospho-2-dehydro-3-deoxy-D-gluconate into pyruvate and glyceraldehyde 3-phosphate. E. coli Eda is a KDPG-aldolase that has also been found to have a role in the degradation of 2-keto-4-hydroxyglutarate (KHG) to pyruvate and glyoxylate []. In fact, KHG-aldolase and Eda are the same enzyme [].This family consists of KHG/KDPG aldolases, and also includes 2-keto-3-deoxy-6-phosphogalactonate (KDPGal) aldolase. KDPGal-aldolase catalyzes an identical reaction to KDPG, differing in substrate specificity in only the configuration of a single stereocentre []. |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ar/Ar<+> Eda/Eda<+> |
| Background: |
involves: 101/H * C3H/HeH |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ar/? Eda/? |
| Background: |
involves: 101/H * C3H/HeH |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gortan Cappellari G |
| Year: |
2016 |
| Journal: |
Sci Rep |
| Title: |
Lack of Fibronectin Extra Domain A Alternative Splicing Exacerbates Endothelial Dysfunction in Diabetes. |
| Volume: |
6 |
|
| Pages: |
37965 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Prakash P |
| Year: |
2015 |
| Journal: |
Blood |
| Title: |
Cellular fibronectin containing extra domain A promotes arterial thrombosis in mice through platelet Toll-like receptor 4. |
| Volume: |
125 |
| Issue: |
20 |
| Pages: |
3164-72 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant stock, spontaneous mutation |
|
•
•
•
•
•
|
| Allele |
| Name: |
fibronectin 1; targeted mutation 2, Francisco E Baralle |
| Allele Type: |
Targeted |
| Attribute String: |
Modified isoform(s) |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 1, David Schlessinger |
| Allele Type: |
Transgenic |
| Attribute String: |
Inducible, Inserted expressed sequence |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant stock, spontaneous mutation |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/? |
| Background: |
involves: C3H/HeSnJ |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/Eda |
| Background: |
involves: C3H/HeSnJ |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/Eda<+> |
| Background: |
involves: C3H/HeSnJ |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/? |
| Background: |
Not Specified |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/Eda<+> |
| Background: |
Not Specified |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/Eda<+> |
| Background: |
involves: 101/H * C3H/HeH * STOCK Myo15/J |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/Eda |
| Background: |
involves: 101/H * C3H/HeH * STOCK Myo15/J |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eda/? |
| Background: |
involves: 101/H * C3H/HeH * STOCK Myo15/J |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE73715 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dhanesha N |
| Year: |
2015 |
| Journal: |
Circulation |
| Title: |
Genetic Ablation of Extra Domain A of Fibronectin in Hypercholesterolemic Mice Improves Stroke Outcome by Reducing Thrombo-Inflammation. |
| Volume: |
132 |
| Issue: |
23 |
| Pages: |
2237-47 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gay D |
| Year: |
2020 |
| Journal: |
Sci Adv |
| Title: |
Phagocytosis of Wnt inhibitor SFRP4 by late wound macrophages drives chronic Wnt activity for fibrotic skin healing. |
| Volume: |
6 |
| Issue: |
12 |
| Pages: |
eaay3704 |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE14877 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE14876 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE14874 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE14873 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE14872 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE14871 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE14870 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| Allele |
| Name: |
fibronectin 1; targeted mutation 1, Francisco E Baralle |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, Modified isoform(s) |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Malara A |
| Year: |
2016 |
| Journal: |
Stem Cells |
| Title: |
Brief Report: Alternative Splicing of Extra Domain A (EIIIA) of Fibronectin Plays a Tissue-Specific Role in Hematopoietic Homeostasis. |
| Volume: |
34 |
| Issue: |
8 |
| Pages: |
2263-8 |
|
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| Publication |
| First Author: |
Bhattacharyya S |
| Year: |
2014 |
| Journal: |
Sci Transl Med |
| Title: |
FibronectinEDA promotes chronic cutaneous fibrosis through Toll-like receptor signaling. |
| Volume: |
6 |
| Issue: |
232 |
| Pages: |
232ra50 |
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| Publication |
| First Author: |
Geiduschek EK |
| Year: |
2024 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
DAMPs Drive Fibroinflammatory Changes in the Glaucomatous ONH. |
| Volume: |
65 |
| Issue: |
12 |
| Pages: |
13 |
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| Genotype |
| Symbol: |
Fn1/Fn1 |
| Background: |
involves: 129X1/SvJ |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
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•
•
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| Genotype |
| Symbol: |
Fn1/Fn1 |
| Background: |
involves: 129X1/SvJ |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
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| Publication |
| First Author: |
Danussi C |
| Year: |
2013 |
| Journal: |
Mol Cell Biol |
| Title: |
EMILIN1/α9β1 integrin interaction is crucial in lymphatic valve formation and maintenance. |
| Volume: |
33 |
| Issue: |
22 |
| Pages: |
4381-94 |
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| Allele |
| Name: |
palate-tail-digits abnormality |
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| Publication |
| First Author: |
Phillips RJS |
| Year: |
1979 |
| Journal: |
Mouse News Lett |
| Title: |
sll-1. |
| Volume: |
60 |
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| Pages: |
45-6 |
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