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Search results 501 to 600 out of 617 for Eed

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Type Details Score
Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
24457600 | J:345192
 
First Author: Cao Q
Year: 2014
Journal: Nat Commun
Title: The central role of EED in the orchestration of polycomb group complexes.
Volume: 5
Pages: 3127
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Publication
9806832 | J:51102
First Author: Schumacher A
Year: 1998
Journal: Genomics
Title: The murine Polycomb-group gene eed and its human orthologue: functional implications of evolutionary conservation.
Volume: 54
Issue: 1
Pages: 79-88
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Protein
Q921E6-2
Organism: Mus musculus/domesticus
Length: 500  
Fragment?: false
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Protein
Q921E6-3
Organism: Mus musculus/domesticus
Length: 427  
Fragment?: false
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HT Experiment
GSE139413 | EED is required for Mouse Primordial Germ Cell Differentiation in the Embryonic Gonad
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE116713 | Maternal Eed knockout causes loss of H3K27me3 imprinting and random X-inactivation in the extra-embryonic cells
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
12123576 | -
First Author: Mak W
Year: 2002
Journal: Curr Biol
Title: Mitotically stable association of polycomb group proteins eed and enx1 with the inactive x chromosome in trophoblast stem cells.
Volume: 12
Issue: 12
Pages: 1016-20
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Publication
9880543 | J:52259
First Author: Peytavi R
Year: 1999
Journal: J Biol Chem
Title: HEED, the product of the human homolog of the murine eed gene, binds to the matrix protein of HIV-1.
Volume: 274
Issue: 3
Pages: 1635-45
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HT Experiment
E-GEOD-83244 | Analysis of changes in gene expression in skin epidermis upon conditional knockout of PRC2-subunit Eed
Series Id: GSE83244
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
21248841 | -
First Author: Margueron R
Year: 2011
Journal: Nature
Title: The Polycomb complex PRC2 and its mark in life.
Volume: 469
Issue: 7330
Pages: 343-9
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Interaction Experiment
Cao Q (2014)
Description: The central role of EED in the orchestration of polycomb group complexes.
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GXD Expression
GXD Expression
 
Probe: MGI:7628718
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-20
Strength: Present
Sex: Female
Emaps: EMAPS:1796525
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:7640208
Age: embryonic day 17.5
Note: Some germ cells were lost in EED hypomorphic mice.
Specimen Label: 5A Eed
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7628718
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-20
Strength: Present
Sex: Female
Emaps: EMAPS:1796525
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:7640208
Age: embryonic day 17.5
Note: Some germ cells were lost in EED hypomorphic mice.
Specimen Label: 5B Eed
Detected: true
Specimen Num: 4
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Publication
8984348 | -
First Author: Schumacher A
Year: 1996
Journal: Nature
Title: Positional cloning of a global regulator of anterior-posterior patterning in mice.
Volume: 384
Issue: 6610
Pages: 648
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Publication
16007070 | -
First Author: Bao S
Year: 2005
Journal: EMBO Rep
Title: Initiation of epigenetic reprogramming of the X chromosome in somatic nuclei transplanted to a mouse oocyte.
Volume: 6
Issue: 8
Pages: 748-54
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Publication
16224021 | -
First Author: Cha TL
Year: 2005
Journal: Science
Title: Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3.
Volume: 310
Issue: 5746
Pages: 306-10
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Publication
16618801 | -
First Author: Bracken AP
Year: 2006
Journal: Genes Dev
Title: Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions.
Volume: 20
Issue: 9
Pages: 1123-36
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Allele
Eed<tm1Smoc> | MGI:7289444
Name: embryonic ectoderm development; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Publication
12689588 | -
First Author: Silva J
Year: 2003
Journal: Dev Cell
Title: Establishment of histone h3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 polycomb group complexes.
Volume: 4
Issue: 4
Pages: 481-95
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Publication
14752160 | J:90454
First Author: Mak W
Year: 2004
Journal: Science
Title: Reactivation of the paternal X chromosome in early mouse embryos.
Volume: 303
Issue: 5658
Pages: 666-9
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Publication
15516932 | J:94241
First Author: Umlauf D
Year: 2004
Journal: Nat Genet
Title: Imprinting along the Kcnq1 domain on mouse chromosome 7 involves repressive histone methylation and recruitment of Polycomb group complexes.
Volume: 36
Issue: 12
Pages: 1296-300
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Publication
15684044 | -
First Author: Kuzmichev A
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation.
Volume: 102
Issue: 6
Pages: 1859-64
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HT Experiment
GSE118263 | Polycomb group proteins regulate chromatin architecture in mouse oocytes and early embryos
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Tg(Eed-EGFP)LZ55Gsat | MGI:4847015
Name: transgene insertion LZ55, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:6354754 | C57BL/6JSmoc-Eed<tm1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
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HT Experiment
GSE207451 | scRNA-seq study of Eed-deleted cerebellar granule neuron progenitors (CGNPs)
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE123331 | Mouse Embryo E11, E13, E15, E18 conditional knockout of EED, with wt controls
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Strain
MGI:5004167 | STOCK Tg(Eed-EGFP)LZ55Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Protein Domain
IPR025644 | DUF4344
Type: Family
Description: This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 247 and 291 amino acids in length. There is a conserved EED sequence motif. This is a putative metallopeptidase.
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HT Experiment
GSE123173 | Switching from Random to Imprinted X-inactivation by Maternal PRC2
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE169395 | Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and EedcKO Forebrain Transcriptomes
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE167921 | Single cell RNA-seq developmental series in mouse hypothalamus in wild-type and Eed-cKO
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE147418 | Epigenetic control of cellular cross-talk defines organ fate and function
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
19026780 | J:142193
First Author: Shen X
Year: 2008
Journal: Mol Cell
Title: EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency.
Volume: 32
Issue: 4
Pages: 491-502
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Publication
23970558 | J:201058
First Author: Nguyen KD
Year: 2013
Journal: Science
Title: Circadian gene Bmal1 regulates diurnal oscillations of Ly6C(hi) inflammatory monocytes.
Volume: 341
Issue: 6153
Pages: 1483-8
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HT Experiment
GSE154995 | Selective Involvement of PRC2 in Mouse Hypothalamus Cell Specification
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE130115 | Allelic histone-to-DNA methylation switch establishes secondary DMR to maintain noncanonical imprinting
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Protein Domain
IPR041343 | PRC2_HTH_1
Type: Domain
Description: This domain can be found in the polycomb repressive complex 2 (PRC2) subunits EZH1 and EZH2. Three core subunits make up the catalytic core of PRC2: EZH1 or EZH2, the zinc-finger containing SUZ12 and EED. Polycomb complexes maintain repressive chromatin states by silencing gene expression. PRC2 does this by methylating lysine 27 of histone H3 []. This domain makes up part of the N-lobe which consists of EED and the N-terminal region of EZH2, and is involved in regulation [].
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HT Experiment
GSE193582 | Transient Polycomb activity represses developmental genes in growing oocytes.
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
17257618 | -
First Author: Ybe JA
Year: 2007
Journal: J Mol Biol
Title: Crystal structure at 2.8 A of the DLLRKN-containing coiled-coil domain of huntingtin-interacting protein 1 (HIP1) reveals a surface suitable for clathrin light chain binding.
Volume: 367
Issue: 1
Pages: 8-15
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Publication
20179344 | -
First Author: Wilbur JD
Year: 2010
Journal: Acta Crystallogr D Biol Crystallogr
Title: Accommodation of structural rearrangements in the huntingtin-interacting protein 1 coiled-coil domain.
Volume: 66
Issue: Pt 3
Pages: 314-8
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Protein Domain
IPR032422 | HIP1_clath-bd
Type: Domain
Description: This entry represents the coiled-coil region of Huntingtin-interacting protein 1 (HIP1). It carries a highly conserved HADLLRKN sequence motif at its N terminus which effects the binding of HIP1R to clathrin light-chain EED regulatory site. This binding then stimulates clathrin lattice assembly. HIP1 is an obligate binding partner for Huntingtin, and loss of this interaction triggers the cascade of events that results in the apoptosis of neuronal cells and the onset of Huntington's disease []. Clathrin light-chain binds to a flexible coiled-coil domain in HIP1 and induces a compact state that is refractory to actin binding [].
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HT Experiment
GSE210398 | Fetal growth delay caused by loss of non-canonical imprinting is resolved late in pregnancy and culminates in offspring overgrowth
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
28387316 | J:253496
 
First Author: Zhang H
Year: 2017
Journal: Nat Commun
Title: Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2.
Volume: 8
Pages: 14922
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Publication
19755104 | J:154927
First Author: Hirabayashi Y
Year: 2009
Journal: Neuron
Title: Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition.
Volume: 63
Issue: 5
Pages: 600-13
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Publication
15493016 | J:94206
First Author: Ohhata T
Year: 2004
Journal: Genesis
Title: X-inactivation is stably maintained in mouse embryos deficient for histone methyl transferase G9a.
Volume: 40
Issue: 3
Pages: 151-6
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Publication
34348118 | J:332698
First Author: Bhattacharjee A
Year: 2021
Journal: Immunity
Title: Environmental enteric dysfunction induces regulatory T cells that inhibit local CD4+ T cell responses and impair oral vaccine efficacy.
Volume: 54
Issue: 8
Pages: 1745-1757.e7
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Publication
24882207 | J:228104
First Author: Cifuentes-Rojas C
Year: 2014
Journal: Mol Cell
Title: Regulatory interactions between RNA and polycomb repressive complex 2.
Volume: 55
Issue: 2
Pages: 171-85
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Publication
25271128 | J:242817
First Author: Vizán P
Year: 2015
Journal: FEBS J
Title: Role of PRC2-associated factors in stem cells and disease.
Volume: 282
Issue: 9
Pages: 1723-35
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Publication
33895473 | J:308819
 
First Author: Wang H
Year: 2021
Journal: Biochem Biophys Res Commun
Title: RNF220-mediated ubiquitination promotes aggresomal accumulation and autophagic degradation of cytoplasmic Gli via HDAC6.
Volume: 557
Pages: 323-328
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Publication
32064321 | J:356091
First Author: Chen Z
Year: 2019
Journal: Sci Adv
Title: Allelic H3K27me3 to allelic DNA methylation switch maintains noncanonical imprinting in extraembryonic cells.
Volume: 5
Issue: 12
Pages: eaay7246
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Protein
F7AQX0
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: true
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Publication
27121947 | -
 
First Author: Justin N
Year: 2016
Journal: Nat Commun
Title: Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2.
Volume: 7
Pages: 11316
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HT Experiment
GSE153530 | Distinct dynamics and functions of H2AK119ub and H3K27me3 in mouse preimplantation embryos (RNA-Seq)
 
Experiment Type: RNA-Seq
Study Type: Baseline and WT vs. Mutant
Source: GEO
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Protein
E9PWK3
Organism: Mus musculus/domesticus
Length: 233  
Fragment?: true
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Protein
Q3U575
Organism: Mus musculus/domesticus
Length: 391  
Fragment?: true
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Protein
Q8C2I5
Organism: Mus musculus/domesticus
Length: 231  
Fragment?: true
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Publication
24144980 | J:206754
First Author: Escamilla-Del-Arenal M
Year: 2013
Journal: Mol Cell Biol
Title: Cdyl, a new partner of the inactive X chromosome and potential reader of H3K27me3 and H3K9me2.
Volume: 33
Issue: 24
Pages: 5005-20
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Publication
11390661 | J:69977
First Author: O'Carroll D
Year: 2001
Journal: Mol Cell Biol
Title: The polycomb-group gene Ezh2 is required for early mouse development.
Volume: 21
Issue: 13
Pages: 4330-6
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Publication
17339329 | J:122229
First Author: Pasini D
Year: 2007
Journal: Mol Cell Biol
Title: The polycomb group protein Suz12 is required for embryonic stem cell differentiation.
Volume: 27
Issue: 10
Pages: 3769-79
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Publication
35676242 | J:325564
First Author: Lian WS
Year: 2022
Journal: Cell Death Dis
Title: Histone H3K27 demethylase UTX compromises articular chondrocyte anabolism and aggravates osteoarthritic degeneration.
Volume: 13
Issue: 6
Pages: 538
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Publication
37729434 | J:343472
First Author: Wu G
Year: 2023
Journal: Sci Transl Med
Title: TP63 fusions drive multicomplex enhancer rewiring, lymphomagenesis, and EZH2 dependence.
Volume: 15
Issue: 714
Pages: eadi7244
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Publication
36790040 | J:338192
First Author: Duong P
Year: 2023
Journal: Glia
Title: Modulation of Schwann cell homeostasis by the BAP1 deubiquitinase.
Volume: 71
Issue: 6
Pages: 1466-1480
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Publication
9765275 | J:50370
First Author: Rietzler M
Year: 1998
Journal: J Biol Chem
Title: The human WD repeat protein WAIT-1 specifically interacts with the cytoplasmic tails of beta7-integrins.
Volume: 273
Issue: 42
Pages: 27459-66
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Publication
20123894 | J:157072
First Author: Li G
Year: 2010
Journal: Genes Dev
Title: Jarid2 and PRC2, partners in regulating gene expression.
Volume: 24
Issue: 4
Pages: 368-80
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Publication
31023785 | J:277111
First Author: Korfhage J
Year: 2019
Journal: Mol Cancer Res
Title: Malignant Peripheral Nerve Sheath Tumors: From Epigenome to Bedside.
Volume: 17
Issue: 7
Pages: 1417-1428
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Publication
17101788 | J:306184
First Author: Yamasaki-Ishizaki Y
Year: 2007
Journal: Mol Cell Biol
Title: Role of DNA methylation and histone H3 lysine 27 methylation in tissue-specific imprinting of mouse Grb10.
Volume: 27
Issue: 2
Pages: 732-42
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Protein
A0A0J9YUA3
Organism: Mus musculus/domesticus
Length: 618  
Fragment?: true
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Protein
Q80UP1
Organism: Mus musculus/domesticus
Length: 682  
Fragment?: true
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Publication
- | J:23411
 
First Author: Maltais LJ
Year: 1994
Journal: Mouse Genome
Title: Locus Map of mouse
Volume: 92
Pages: 62-85
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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