Search our database by keyword

Examples

Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 501 to 533 out of 533 for Ephb4

<< First < Previous | Next > Last >>

0.018s

Type

Details

Score

DO Term

DOID:0081030 | central conducting lymphatic anomaly

•

Protein Domain

IPR034290 | EphB4_rcpt_lig-bd

Type:

Domain

Description:

This entry represents the ligand-binding domain found in ephrin type-B receptor 4 (EphB4). EphB4 has been implicated in a number of cancers [, , , ]. It has also been shown to play a role in osteoblast differentiation []. Class EphB receptors bind to transmembrane ephrin-B ligands. There are six vertebrate EhpB receptors (EphB1-6), which display promiscuous interactions with three ephrin-B ligands [].Ephrin receptors (EphRs) comprise the largest subfamily of receptor tyrosine kinases (RTKs). EphRs contain a ligand binding domain and two fibronectin repeats extracellularly, a transmembrane segment, and a cytoplasmic tyrosine kinase domain. Binding of the ephrin ligand to EphR requires cell-cell contact since both are anchored to the plasma membrane. The resulting downstream signals occur bidirectionally in both EphR-expressing cells (forward signaling) and ephrin-expressing cells (reverse signaling) [].

•

Publication

26481148 | J:226762

First Author:	Pradeep S
Year:	2015
Journal:	Cancer Cell
Title:	Erythropoietin Stimulates Tumor Growth via EphB4.
Volume:	28
Issue:	5
Pages:	610-622

•

Publication

33789115 | J:304276

First Author:	Bissen D
Year:	2021
Journal:	Cell Rep
Title:	EphrinB2 and GRIP1 stabilize mushroom spines during denervation-induced homeostatic plasticity.
Volume:	34
Issue:	13
Pages:	108923

•

Publication

38570531 | J:361362

First Author:	Stewen J
Year:	2024
Journal:	Nat Commun
Title:	Eph-ephrin signaling couples endothelial cell sorting and arterial specification.
Volume:	15
Issue:	1
Pages:	2539

•

Publication

19299512 | J:175143

First Author:	Irie N
Year:	2009
Journal:	J Biol Chem
Title:	Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesis.
Volume:	284
Issue:	21
Pages:	14637-44

•

Publication

26878170 | J:232423

First Author:	Teramachi J
Year:	2016
Journal:	J Clin Invest
Title:	Measles virus nucleocapsid protein increases osteoblast differentiation in Paget's disease.
Volume:	126
Issue:	3
Pages:	1012-22

•

Publication

17234965 | J:133690

First Author:	Limbourg A
Year:	2007
Journal:	Circ Res
Title:	Notch ligand Delta-like 1 is essential for postnatal arteriogenesis.
Volume:	100
Issue:	3
Pages:	363-71

•

Publication

26407069 | J:243324

First Author:	Mimche PN
Year:	2015
Journal:	PLoS One
Title:	Expression of the Receptor Tyrosine Kinase EphB2 on Dendritic Cells Is Modulated by Toll-Like Receptor Ligation but Is Not Required for T Cell Activation.
Volume:	10
Issue:	9
Pages:	e0138835

•

Publication

22622783 | J:187764

First Author:	Kawano H
Year:	2012
Journal:	Eur J Immunol
Title:	A novel feedback mechanism by Ephrin-B1/B2 in T-cell activation involves a concentration-dependent switch from costimulation to inhibition.
Volume:	42
Issue:	6
Pages:	1562-72

•

Publication

19843150 | J:166309

First Author:	Weiler S
Year:	2009
Journal:	Dev Growth Differ
Title:	Mammary epithelial-specific knockout of the ephrin-B2 gene leads to precocious epithelial cell death at lactation.
Volume:	51
Issue:	9
Pages:	809-19

•

Publication

32323401 | J:322864

First Author:	Hamard L
Year:	2020
Journal:	FASEB J
Title:	Targeting connexin37 alters angiogenesis and arteriovenous differentiation in the developing mouse retina.
Volume:	34
Issue:	6
Pages:	8234-8249

•

Publication

22789927 | J:213971

First Author:	Taylor AC
Year:	2012
Journal:	Invest Ophthalmol Vis Sci
Title:	Attenuation of ephrinB2 reverse signaling decreases vascularized area and preretinal vascular tuft formation in the murine model of oxygen-induced retinopathy.
Volume:	53
Issue:	9
Pages:	5462-70

•

Publication

29058717 | J:252612

First Author:	Lagares D
Year:	2017
Journal:	Nat Med
Title:	ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis.
Volume:	23
Issue:	12
Pages:	1405-1415

•

Publication

16596241 | J:120093

First Author:	Katoh M
Year:	2006
Journal:	Int J Oncol
Title:	Comparative integromics on Eph family.
Volume:	28
Issue:	5
Pages:	1243-7

•

Publication

18406338 | J:135161

First Author:	Matsuo K
Year:	2008
Journal:	Arch Biochem Biophys
Title:	Osteoclast-osteoblast communication.
Volume:	473
Issue:	2
Pages:	201-9

•

Publication

18948631 | J:155271

First Author:	Aitsebaomo J
Year:	2008
Journal:	Circ Res
Title:	Brothers and sisters: molecular insights into arterial-venous heterogeneity.
Volume:	103
Issue:	9
Pages:	929-39

•

Publication

20133818 | J:158640

First Author:	Fuxe J
Year:	2010
Journal:	Am J Pathol
Title:	Angiopoietin/Tie2 signaling transforms capillaries into venules primed for leukocyte trafficking in airway inflammation.
Volume:	176
Issue:	4
Pages:	2009-18

•

Publication

23492730 | J:329592

First Author:	Kida Y
Year:	2013
Journal:	J Am Soc Nephrol
Title:	EphrinB2 reverse signaling protects against capillary rarefaction and fibrosis after kidney injury.
Volume:	24
Issue:	4
Pages:	559-72

•

Publication

21852108 | J:184954

First Author:	Herath NI
Year:	2012
Journal:	Eur J Cancer
Title:	Complex expression patterns of Eph receptor tyrosine kinases and their ephrin ligands in colorectal carcinogenesis.
Volume:	48
Issue:	5
Pages:	753-62

•

Publication

25830332 | J:233431

First Author:	Jahnsen ED
Year:	2015
Journal:	PLoS One
Title:	Notch1 is pan-endothelial at the onset of flow and regulated by flow.
Volume:	10
Issue:	4
Pages:	e0122622

•

Publication

27725190 | J:250989

First Author:	Sharifpanah F
Year:	2016
Journal:	Biochim Biophys Acta
Title:	Mechanical strain stimulates vasculogenesis and expression of angiogenesis guidance molecules of embryonic stem cells through elevation of intracellular calcium, reactive oxygen species and nitric oxide generation.
Volume:	1863
Issue:	12
Pages:	3096-3105

•

Publication

32078587 | J:301919

First Author:	Miyagawa K
Year:	2020
Journal:	JCI Insight
Title:	Osteoclast-derived IGF1 is required for pagetic lesion formation in vivo.
Volume:	5
Issue:	6

•

Publication

18206868 | J:131987

First Author:	Dimaio TA
Year:	2008
Journal:	Dev Biol
Title:	Attenuation of retinal vascular development and neovascularization in PECAM-1-deficient mice.
Volume:	315
Issue:	1
Pages:	72-88

•

Publication

11161569 | J:67371

First Author:	Gale NW
Year:	2001
Journal:	Dev Biol
Title:	Ephrin-B2 selectively marks arterial vessels and neovascularization sites in the adult, with expression in both endothelial and smooth-muscle cells.
Volume:	230
Issue:	2
Pages:	151-60

•

Publication

15223333 | J:91492

First Author:	Cowan CA
Year:	2004
Journal:	Dev Biol
Title:	Ephrin-B2 reverse signaling is required for axon pathfinding and cardiac valve formation but not early vascular development.
Volume:	271
Issue:	2
Pages:	263-71

•

Publication

12495863 | -

First Author:	Himanen JP
Year:	2003
Journal:	Trends Neurosci
Title:	Eph signaling: a structural view.
Volume:	26
Issue:	1
Pages:	46-51

•

Protein

P54761

Organism:	Mus musculus/domesticus
Length:	987
Fragment?:	false

•

Protein

Q91YM0

Organism:	Mus musculus/domesticus
Length:	987
Fragment?:	false

•

Protein

Q3V1K8

Organism:	Mus musculus/domesticus
Length:	987
Fragment?:	false

•

Protein

E9PWK7

Organism:	Mus musculus/domesticus
Length:	935
Fragment?:	false

•

Protein

Q8C7S3

Organism:	Mus musculus/domesticus
Length:	987
Fragment?:	false

•

Protein

Q8C8K1

Organism:	Mus musculus/domesticus
Length:	996
Fragment?:	false

•

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/keywordSearchResults.do?searchOffset=500&searchTerm=Ephb4

MouseMine

Search our database by keyword

Examples

Search results 501 to 533 out of 533 for Ephb4

Categories

Hits by Pathway

Hits by Category

Hits by Strain