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Search results 501 to 600 out of 887 for Etv6

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0.029s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Protein Domain
IPR013761 | SAM/pointed_sf
Type: Homologous_superfamily
Description: Sterile alpha motif (SAM) domains are known to be involved in diverse protein-protein interactions, associating with both SAM-containing and non-SAM-containing proteins pathway []. SAM domains exhibit a conserved structure, consisting of a 4-5-helical bundle of two orthogonally packed alpha-hairpins. However SAM domains display a diversity of function, being involved in interactions with proteins, DNA and RNA []. The name sterile alpha motif arose from its presence in proteins that are essential for yeast sexual differentiation. The SAM domain has had various names, including SPM, PTN (pointed), SEP (yeast sterility, Ets-related, PcG proteins), NCR (N-terminal conserved region) and HLH (helix-loop-helix) domain, all of which are related and can be classified as SAM domains.SAM domains occur in eukaryotic and in some bacterial proteins. Structures have been determined for several proteins that contain SAM domains, including Ets-1 transcription factor, which plays a role in the development and invasion of tumour cells by regulating the expression of matrix-degrading proteases []; Etv6 transcription factor, gene rearrangements of which have been demonstrated in several malignancies []; EphA4 receptor tyrosine kinase, which is believed to be important for the correct localization of a motoneuron pool to a specific position in the spinal cord []; EphB2 receptor, which is involved in spine morphogenesis via intersectin, Cdc42 and N-Wasp []; p73, a p53 homologue involved in neuronal development []; and polyhomeotic, which is a member of the Polycomb group of genes (Pc-G) required for the maintenance of the spatial expression pattern of homeotic genes [].
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Protein
Q8R3Y5
Organism: Mus musculus/domesticus
Length: 413  
Fragment?: false
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Protein
Q5SXE1
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: true
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Protein
A0A087WPA4
Organism: Mus musculus/domesticus
Length: 190  
Fragment?: true
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Protein
D2JZZ5
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: true
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Protein
G5E8E3
Organism: Mus musculus/domesticus
Length: 413  
Fragment?: false
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Protein
A0A0R4J2B5
Organism: Mus musculus/domesticus
Length: 391  
Fragment?: false
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Protein
A0A087WRI8
Organism: Mus musculus/domesticus
Length: 397  
Fragment?: false
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Protein
Q5SXE2
Organism: Mus musculus/domesticus
Length: 205  
Fragment?: true
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Protein
Q6PAJ3
Organism: Mus musculus/domesticus
Length: 880  
Fragment?: false
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Protein
Q3UFT3
Organism: Mus musculus/domesticus
Length: 876  
Fragment?: false
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Protein
Q6TDG7
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: true
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Protein
Q8CC79
Organism: Mus musculus/domesticus
Length: 217  
Fragment?: true
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Protein
A0A3B2WCY8
Organism: Mus musculus/domesticus
Length: 282  
Fragment?: true
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Protein
D3Z292
Organism: Mus musculus/domesticus
Length: 66  
Fragment?: true
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Publication
12858164 | -
First Author: Aviv T
Year: 2003
Journal: Nat Struct Biol
Title: The RNA-binding SAM domain of Smaug defines a new family of post-transcriptional regulators.
Volume: 10
Issue: 8
Pages: 614-21
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Protein
Q61127
Organism: Mus musculus/domesticus
Length: 525  
Fragment?: false
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Protein
Q8K070
Organism: Mus musculus/domesticus
Length: 417  
Fragment?: false
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Protein
F6XZJ7
Organism: Mus musculus/domesticus
Length: 620  
Fragment?: false
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Protein
D3YXK1
Organism: Mus musculus/domesticus
Length: 519  
Fragment?: false
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Protein
Q60710
Organism: Mus musculus/domesticus
Length: 658  
Fragment?: false
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Protein
Q8VCQ6
Organism: Mus musculus/domesticus
Length: 419  
Fragment?: false
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Protein
Q8C8Y5
Organism: Mus musculus/domesticus
Length: 445  
Fragment?: false
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Protein
Q69Z37
Organism: Mus musculus/domesticus
Length: 1561  
Fragment?: false
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Protein
Q8C4H2
Organism: Mus musculus/domesticus
Length: 520  
Fragment?: false
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Protein
Q9DA37
Organism: Mus musculus/domesticus
Length: 478  
Fragment?: false
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Protein
Q7TST3
Organism: Mus musculus/domesticus
Length: 202  
Fragment?: false
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Protein
Q1RNF8
Organism: Mus musculus/domesticus
Length: 542  
Fragment?: false
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Protein
Q0VE29
Organism: Mus musculus/domesticus
Length: 161  
Fragment?: false
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Protein
D3YUG0
Organism: Mus musculus/domesticus
Length: 102  
Fragment?: false
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Protein
Q3V1H9
Organism: Mus musculus/domesticus
Length: 173  
Fragment?: false
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Protein
Q6NZC7
Organism: Mus musculus/domesticus
Length: 998  
Fragment?: false
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Protein
Q9ERA0
Organism: Mus musculus/domesticus
Length: 502  
Fragment?: false
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Protein
Q3UNW5
Organism: Mus musculus/domesticus
Length: 479  
Fragment?: false
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Protein
Q80VG1
Organism: Mus musculus/domesticus
Length: 408  
Fragment?: false
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Protein
Q811S7
Organism: Mus musculus/domesticus
Length: 540  
Fragment?: false
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Protein
Q3UH82
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: false
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Protein
Q3U247
Organism: Mus musculus/domesticus
Length: 342  
Fragment?: false
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Protein
Q8C5C0
Organism: Mus musculus/domesticus
Length: 551  
Fragment?: false
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Protein
E9Q3G4
Organism: Mus musculus/domesticus
Length: 514  
Fragment?: false
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Protein
Q3TYF1
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
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Protein
Q14AQ4
Organism: Mus musculus/domesticus
Length: 478  
Fragment?: false
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Protein
B9EKF8
Organism: Mus musculus/domesticus
Length: 300  
Fragment?: false
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Protein
C4IXV3
Organism: Mus musculus/domesticus
Length: 330  
Fragment?: false
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Protein
Q3UR41
Organism: Mus musculus/domesticus
Length: 166  
Fragment?: false
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Protein
S4R2K2
Organism: Mus musculus/domesticus
Length: 76  
Fragment?: false
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Protein
Q4G0C0
Organism: Mus musculus/domesticus
Length: 998  
Fragment?: false
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Protein
Q8CCF9
Organism: Mus musculus/domesticus
Length: 44  
Fragment?: true
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Protein
Q3TBN2
Organism: Mus musculus/domesticus
Length: 202  
Fragment?: false
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Protein
E9PX59
Organism: Mus musculus/domesticus
Length: 1579  
Fragment?: false
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Protein
Q3UDX7
Organism: Mus musculus/domesticus
Length: 411  
Fragment?: true
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Protein
A2BGK7
Organism: Mus musculus/domesticus
Length: 141  
Fragment?: true
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Protein
Q3TCJ7
Organism: Mus musculus/domesticus
Length: 620  
Fragment?: false
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Protein
J3QN61
Organism: Mus musculus/domesticus
Length: 552  
Fragment?: false
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Protein
Q8BY88
Organism: Mus musculus/domesticus
Length: 190  
Fragment?: true
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Protein
V9GX63
Organism: Mus musculus/domesticus
Length: 103  
Fragment?: true
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Protein
A2BIB7
Organism: Mus musculus/domesticus
Length: 181  
Fragment?: true
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Protein
F6TVP2
Organism: Mus musculus/domesticus
Length: 631  
Fragment?: true
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Protein
Q05CZ7
Organism: Mus musculus/domesticus
Length: 247  
Fragment?: true
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Protein
A2BIB6
Organism: Mus musculus/domesticus
Length: 127  
Fragment?: true
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Protein
B2RUD2
Organism: Mus musculus/domesticus
Length: 504  
Fragment?: false
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Protein
Q3URS4
Organism: Mus musculus/domesticus
Length: 326  
Fragment?: true
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Protein
D2JZZ6
Organism: Mus musculus/domesticus
Length: 216  
Fragment?: true
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Protein
B1AVB3
Organism: Mus musculus/domesticus
Length: 969  
Fragment?: false
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Protein
A0A0G2JGB1
Organism: Mus musculus/domesticus
Length: 83  
Fragment?: false
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Protein
Q80TH3
Organism: Mus musculus/domesticus
Length: 395  
Fragment?: true
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Protein
D3Z2S2
Organism: Mus musculus/domesticus
Length: 57  
Fragment?: true
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Protein
A0A2R8VHN6
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: true
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Protein
Q8R5E8
Organism: Mus musculus/domesticus
Length: 265  
Fragment?: true
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Protein
A0A140LHS5
Organism: Mus musculus/domesticus
Length: 432  
Fragment?: true
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Protein
A0A0R4J186
Organism: Mus musculus/domesticus
Length: 173  
Fragment?: false
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Protein
E0CXD0
Organism: Mus musculus/domesticus
Length: 126  
Fragment?: true
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Protein
Q3TPQ4
Organism: Mus musculus/domesticus
Length: 238  
Fragment?: true
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Protein
G3X928
Organism: Mus musculus/domesticus
Length: 998  
Fragment?: false
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Protein
A0A494BA77
Organism: Mus musculus/domesticus
Length: 293  
Fragment?: false
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Protein
V9GX50
Organism: Mus musculus/domesticus
Length: 209  
Fragment?: true
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Protein
A0A140LI45
Organism: Mus musculus/domesticus
Length: 190  
Fragment?: true
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Protein
A0A140LJ14
Organism: Mus musculus/domesticus
Length: 138  
Fragment?: true
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Protein
E9PYG9
Organism: Mus musculus/domesticus
Length: 582  
Fragment?: false
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Protein
A0A3B2WCI8
Organism: Mus musculus/domesticus
Length: 131  
Fragment?: true
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Protein
E0CXZ5
Organism: Mus musculus/domesticus
Length: 150  
Fragment?: false
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Protein
A0A571BEU3
Organism: Mus musculus/domesticus
Length: 211  
Fragment?: false
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Protein
A0A2R8VKI7
Organism: Mus musculus/domesticus
Length: 505  
Fragment?: false
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Protein
Q497L5
Organism: Mus musculus/domesticus
Length: 432  
Fragment?: false
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Protein
A0A3B2W446
Organism: Mus musculus/domesticus
Length: 82  
Fragment?: true
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Protein
B7ZN34
Organism: Mus musculus/domesticus
Length: 151  
Fragment?: false
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Protein
Q3U754
Organism: Mus musculus/domesticus
Length: 260  
Fragment?: true
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Protein
F6W657
Organism: Mus musculus/domesticus
Length: 46  
Fragment?: true
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Protein
A0A2I3BPX6
Organism: Mus musculus/domesticus
Length: 820  
Fragment?: false
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Protein
D3Z5Y1
Organism: Mus musculus/domesticus
Length: 111  
Fragment?: true
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Protein
A0A571BGE2
Organism: Mus musculus/domesticus
Length: 130  
Fragment?: true
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Protein
Q3TBL2
Organism: Mus musculus/domesticus
Length: 525  
Fragment?: false
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Protein
D3YZJ7
Organism: Mus musculus/domesticus
Length: 54  
Fragment?: true
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Protein
Q8BRY6
Organism: Mus musculus/domesticus
Length: 153  
Fragment?: false
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Protein
E3W996
Organism: Mus musculus/domesticus
Length: 220  
Fragment?: false
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Protein
A0AUN0
Organism: Mus musculus/domesticus
Length: 842  
Fragment?: true
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Publication
14659692 | -
First Author: Kim CA
Year: 2003
Journal: Trends Biochem Sci
Title: SAM domains: uniform structure, diversity of function.
Volume: 28
Issue: 12
Pages: 625-8
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Protein
Q80T11
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
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Protein
Q8K3X6
Organism: Mus musculus/domesticus
Length: 423  
Fragment?: false
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Protein
P81270
Organism: Mus musculus/domesticus
Length: 486  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom