| Type |
Details |
Score |
| Allele |
| Name: |
Fc receptor, IgG, low affinity IIb; autoimmune Fcgr2 promoter haplotype |
| Allele Type: |
Spontaneous |
| Attribute String: |
Hypomorph |
|
•
•
•
•
•
|
| Allele |
| Name: |
Fc receptor, IgG, low affinity IIb; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
| Allele |
| Name: |
Fc receptor, IgG, low affinity IIb; endonuclease-mediated mutation 3, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Allele |
| Name: |
Fc receptor, IgG, low affinity IIb; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
Fc receptor, IgG, low affinity III; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
Fc receptor, IgG, low affinity IV; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
330
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
283
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
302
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Allele |
| Name: |
Fc receptor, IgG, low affinity IIb; endonuclease-mediated mutation 1, Synbal |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Humanized sequence, Inserted expressed sequence, Null/knockout |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, spontaneous mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bersellini Farinotti A |
| Year: |
2019 |
| Journal: |
J Exp Med |
| Title: |
Cartilage-binding antibodies induce pain through immune complex-mediated activation of neurons. |
| Volume: |
216 |
| Issue: |
8 |
| Pages: |
1904-1924 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jonsson S |
| Year: |
2017 |
| Journal: |
Nat Genet |
| Title: |
Identification of sequence variants influencing immunoglobulin levels. |
| Volume: |
49 |
| Issue: |
8 |
| Pages: |
1182-1191 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kimura J |
| Year: |
2014 |
| Journal: |
Genes Immun |
| Title: |
BXSB-type genome causes murine autoimmune glomerulonephritis: pathological correlation between telomeric region of chromosome 1 and Yaa. |
| Volume: |
15 |
| Issue: |
3 |
| Pages: |
182-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nomura H |
| Year: |
2022 |
| Journal: |
J Immunol |
| Title: |
IgM to IgG Class Switching Is a Necessary Step for Pemphigus Phenotype Induction in Desmoglein 3-Specific B Cell Receptor Knock-in Mouse. |
| Volume: |
208 |
| Issue: |
3 |
| Pages: |
582-593 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kumpunya S |
| Year: |
2022 |
| Journal: |
Front Immunol |
| Title: |
cGAS deficiency enhances inflammasome activation in macrophages and inflammatory pathology in pristane-induced lupus. |
| Volume: |
13 |
|
| Pages: |
1010764 |
|
•
•
•
•
•
|