|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 501 to 527 out of 527 for Frem2

<< First    < Previous  |  Next >    Last >>
0.013s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Genotype
Genotype
Symbol: Frem1/Frem1
Background: involves: AKR/J
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Grip1/Grip1
Background: involves: ATEB/Le * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Frem2/Frem2
Background: STOCK Frem2/GrsrJ
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Fras1/Fras1
Background: involves: 129S1/Sv * 129X1/SvJ * NMRI
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Frem2/Frem2
Background: C57BL/6J-Frem2
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Fras1/Fras1
Background: involves: C57BL/6JAnu
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
DO Term
DOID:0090001 | Fraser syndrome
•
•
•
•
•
Genotype
Genotype
Symbol: Frem2/Frem2
Background: MY/HuLeJ
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Frem3/Frem3
Background: involves: C57BL/6NJcl * DBA/2NJcl
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Fras1/Fras1
Background: involves: C57BL/6J * FVB/NJ
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Protein Domain
IPR032825 | FREM1
Type: Family
Description: FREM1 (FRAS1-related extracellular matrix protein 1) is an extracellular matrix protein that forms a ternary complex in the basement membrane with FRAS1 and FREM2 during epidermal development []. FREM1 also appears to act as a dermal mediator of basement membrane adhesion independently of the FRAS1 []. Mutations in the FREM1 gene cause two rare syndromes - bifid nose with or without anorectal and renal anomalies syndrome (BNAR; OMIM #608980) and Manitoba oculotrichoanal syndrome (MOTA; OMIM #248450) - whose phenotypic characteristics overlap those seen in individuals with Fraser syndrome [].
•
•
•
•
•
Protein Coding Gene
MGI:2385368 | Fras1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Genotype
Genotype
Symbol: Fras1/Fras1
Background: involves: 101/H * C3H/HeH
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Protein Coding Gene
MGI:1921303 | Grip1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Genotype
Genotype
Symbol: Frem1/Frem1
Background: C57BL/6J-Frem1
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Publication
31554749 | J:291067
First Author: Kiyozumi D
Year: 2020
Journal: Exp Anim
Title: Genetic mutation of Frem3 does not causeFraser syndrome in mice.
Volume: 69
Issue: 1
Pages: 104-109
•
•
•
•
•
Publication
21182980 | -
First Author: Pavlakis E
Year: 2011
Journal: Int J Biochem Cell Biol
Title: The role of Fras1/Frem proteins in the structure and function of basement membrane.
Volume: 43
Issue: 4
Pages: 487-95
•
•
•
•
•
Protein Coding Gene
MGI:2670972 | Frem1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Publication
15345741 | J:92613
First Author: Smyth I
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis.
Volume: 101
Issue: 37
Pages: 13560-5
•
•
•
•
•
Protein
F7D5I3
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: true
•
•
•
•
•
Publication
24232570 | J:208091
First Author: Richardson RJ
Year: 2014
Journal: J Invest Dermatol
Title: AMACO is a component of the basement membrane-associated Fraser complex.
Volume: 134
Issue: 5
Pages: 1313-1322
•
•
•
•
•
Publication
21507892 | J:200884
First Author: Slavotinek AM
Year: 2011
Journal: J Med Genet
Title: Manitoba-oculo-tricho-anal (MOTA) syndrome is caused by mutations in FREM1.
Volume: 48
Issue: 6
Pages: 375-82
•
•
•
•
•
Protein
Q5H8B9
Organism: Mus musculus/domesticus
Length: 2123  
Fragment?: false
•
•
•
•
•
Protein
F8WHZ0
Organism: Mus musculus/domesticus
Length: 2127  
Fragment?: false
•
•
•
•
•
Protein
Q684R7
Organism: Mus musculus/domesticus
Length: 2191  
Fragment?: false
•
•
•
•
•
Protein
A2ADN1
Organism: Mus musculus/domesticus
Length: 2172  
Fragment?: false
•
•
•
•
•
Protein
E9Q5Z7
Organism: Mus musculus/domesticus
Length: 2173  
Fragment?: false
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom