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Search results 501 to 600 out of 637 for Gnas

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Type Details Score
Allele
Gnas<tm5Lsw> | MGI:6407048
Name: GNAS complex locus; targeted mutation 5, Lee S Weinstein
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Gnas<em17Gpt> | MGI:7299693
Name: GNAS complex locus; endonuclease-mediated mutation 17, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Gnas<em1Gpt> | MGI:7299694
Name: GNAS complex locus; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Gnas<em1Cya> | MGI:7584052
Name: GNAS complex locus; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Tg(PGK1-Gnas*R201C)60Pabi/?
Background: either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * FVB/N)
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(EEF1A1-Gnas*R201C)184Pabi/?
Background: either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * FVB/N)
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas<+>
Background: involves: 129S2/SvPas * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas<+>
Background: involves: 129S2/SvPas * C57BL/6J * CD-1
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas<+>
Background: involves: 129P2/OlaHsd * C57BL/6J * DS/2
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas<+>
Background: involves: 129S2/SvPas
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas<+>
Background: involves: 129S2/SvPas * CD-1
Zygosity: ht
Has Mutant Allele: true
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DO Term
DOID:0111623 | ACTH-independent macronodular adrenal hyperplasia 1
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Publication
30962325 | J:285927
First Author: Miyado M
Year: 2019
Journal: J Am Soc Nephrol
Title: Germline-Derived Gain-of-Function Variants of Gsα-Coding GNAS Gene Identified in Nephrogenic Syndrome of Inappropriate Antidiuresis.
Volume: 30
Issue: 5
Pages: 877-889
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Genotype
Genotype
Symbol: Gnasas1/Gnasas1
Background: involves: 129S/SvEv * 129S1/Sv
Zygosity: ht
Has Mutant Allele: true
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Strain
MGI:4887565 | 129S/SvEv-Gnas<tm1Jop>/H
Attribute String: coisogenic, mutant strain, targeted mutation
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Strain
MGI:5490273 | 129S(B6)-Gnas<tm2Kel>/H
Attribute String: targeted mutation
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Strain
MGI:5492389 | B6.129S1-Gnas<tm2Kel>/H
Attribute String: targeted mutation, congenic
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Strain
MGI:6407056 | STOCK Gnas<tm5.1Lsw>/J
Attribute String: mutant stock, targeted mutation
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Allele
Gnasas1<Gt(EUCE0077f03)Hmgu> | MGI:4369867
 
Name: GNAS antisense RNA 1; gene trap EUCE0077f03, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Gnasas1<Gt(EUCE0169f06)Hmgu> | MGI:4377555
 
Name: GNAS antisense RNA 1; gene trap EUCE0169f06, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Gnasas1<Gt(EUCE0286a08)Hmgu> | MGI:4383330
 
Name: GNAS antisense RNA 1; gene trap EUCE0286a08, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Gnasas1<Gt(296H3)Cmhd> | MGI:4965148
 
Name: GNAS antisense RNA 1; gene trap 296H3, Centre for Modeling Human Disease
Allele Type: Gene trapped
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Allele
Gnasas1<Gt(IST10897C8)Tigm> | MGI:5145661
 
Name: GNAS antisense RNA 1; gene trap IST10897C8, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Gnasas1<Gt(IST14214A8)Tigm> | MGI:5216045
 
Name: GNAS antisense RNA 1; gene trap IST14214A8, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Gnasas1<Gt(IST14389G6)Tigm> | MGI:5230259
 
Name: GNAS antisense RNA 1; gene trap IST14389G6, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Gnas<Gt(IST15034D4)Tigm> | MGI:5277993
 
Name: GNAS complex locus; gene trap IST15034D4, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Gnas<Gt(IST15036D4)Tigm> | MGI:5278134
 
Name: GNAS complex locus; gene trap IST15036D4, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Gnas<Gt(IST15036E4)Tigm> | MGI:5278144
 
Name: GNAS complex locus; gene trap IST15036E4, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Strain
MGI:7591155 | C57BL/6J-Gnas<em1Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Gnasas1<em1Smoc> | MGI:7626469
Name: GNAS antisense RNA 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Gnas/Gnas<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas<+>
Background: involves: 101/H * C3H/HeH
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas<+>
Background: involves: 101/H * C3H/HeH * M. m. castaneus
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas
Background: involves: 129S6/SvEvTac * Black Swiss * CD-1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas
Background: involves: 129S4/SvJae * CD-1
Zygosity: hm
Has Mutant Allele: true
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Gene
8675 | STX16
Type: gene
Organism: human
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DO Term
DOID:0051013 | pseudohypoparathyroidism type 1C
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Genotype
Genotype
Symbol: Gnas/Gnas<+> Gnasas1/Gnasas1<+>
Background: involves: 101/H * 129S/SvEv * C3H/HeH
Zygosity: cx
Has Mutant Allele: true
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Allele
Tg(tetO-HTR4*D100A)2Niss | MGI:4367596
Name: transgene insertion 2, Robert A Nissenson
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
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HT Experiment
E-GEOD-60415 | The G-protein Alpha Subunit Gs alpha Is A Tumor Suppressor In Sonic Hedgehog-driven Medulloblastoma [RNA-Seq]
Series Id: GSE60415
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Strain
MGI:6475394 | C57BL/6JSmoc-Gnasas1<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Gnas/Gnas<+>
Background: involves: 129S/SvEv * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas
Background: involves: 129S/SvEv * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas Tg(Col2a1-cre)1Rsjo/?
Background: involves: 129S6/SvEvTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas<+>
Background: involves: 129S6/SvEvTac * Black Swiss * CD-1
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas<+>
Background: either: (involves: 129S1/Sv) or (involves: 129S1/Sv * C57BL/6J)
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas Tg(Alb1-cre)1Dlr/?
Background: involves: 129S6/SvEvTac * Black Swiss * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas<+>
Background: involves: 129S4/SvJae * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas<+>
Background: either: (involves: 129S4/SvJae * 129/Sv) or (involves: 129S4/SvJae * C57BL/6J) or (involves: 129S4/SvJae * CD-1)
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas<+>
Background: involves: 129S4/SvJae * CD-1
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas<+>
Background: involves: 129S4/SvJae
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas Tg(Fabp4-cre)1Abel/?
Background: involves: FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnasas1/Gnasas1<+>
Background: either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * C57BL/6J)
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Nespas/Gnas<+>
Background: involves: 129S/SvEv * 129S1/Sv
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnasas1/Gnasas1<+>
Background: involves: 129S/SvEv * 129S1/Sv
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Nespas/Gnas<+>
Background: involves: 129S/SvEv * 129S1/Sv
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnasas1/Gnasas1<+>
Background: involves: 129S/SvEv * 129S1/Sv
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Nespas/Gnas<+>
Background: involves: 129S1/Sv * M. spretus
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnasas1/Gnasas1<+>
Background: involves: 129S1/Sv * M. spretus
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas<+>
Background: involves: 129S/SvEv
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas<+>
Background: involves: 129S/SvEv
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas<+>
Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6 * CD-1 * SJL
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas<+>
Background: involves: 129S4/SvJae * C57BL/6 * C57BL/6J * SJL
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas<+>
Background: involves: 129S4/SvJae * C57BL/6 * CD-1 * SJL
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas Tg(TPO-cre)1Shk/?
Background: involves: 129S6/SvEvTac * FVB/NCr
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas Tg(Gfy-cre)1Yyos/?
Background: involves: 129S6/SvEvTac * Black Swiss * C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas Tg(Slc5a2-cre)1Tauc/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas Tg(Nes-cre)1Atp/?
Background: involves: 129S6/SvEvTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas Tg(GFAP-cre)25Mes/?
Background: involves: C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Publication
21172659 | J:168094
First Author: Zhao J
Year: 2010
Journal: Mol Cell
Title: Genome-wide identification of polycomb-associated RNAs by RIP-seq.
Volume: 40
Issue: 6
Pages: 939-53
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Allele
Tg(Or10j5-Gnas*Q227L,-EYFP)1Hsak | MGI:7442215
Name: transgene insertion 1, Hitoshi Sakano
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
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Transgene
MGI:4367597 | Tg(tetO-HTR4*D100A)2Niss
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5883013 | Tg(PGK1-Gnas*R201C)60Pabi
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5883022 | Tg(EEF1A1-Gnas*R201C)184Pabi
Type: transgene
Organism: mouse, laboratory
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Genotype
Genotype
Symbol: Tg(Col1a1-tTA)139Niss/? Tg(tetO-HTR4*D100A)2Niss/?
Background: FVB/N-Tg(Col1a1-tTA)139Niss Tg(tetO-HTR4*D100A)2Niss
Zygosity: cx
Has Mutant Allele: true
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DO Term
DOID:1858 | McCune Albright syndrome
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DO Term
DOID:0112010 | pituitary adenoma 3
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DO Term
DOID:0111535 | progressive osseous heteroplasia
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Allele
Gpa33<tm1(GNAS)Wtsi> | MGI:4889205
Name: glycoprotein A33 transmembrane; targeted mutation 1, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Constitutively active, Humanized sequence, Inserted expressed sequence
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Allele
Tg(RP1-309F20*)48Kel | MGI:5308373
Name: transgene insertion 48, Gavin Derek Kelsey
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Or8a1<tm40(Gnas*)Mom> | MGI:5788006
Name: olfactory receptor family 8 subfamily A member 1; targeted mutation 40, Peter Mombaerts
Allele Type: Targeted
Attribute String: Constitutively active, Inserted expressed sequence, Reporter
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Allele
Or8a1<tm39(Gnas*)Mom> | MGI:5784884
Name: olfactory receptor family 8 subfamily A member 1; targeted mutation 39, Peter Mombearts
Allele Type: Targeted
Attribute String: Constitutively active, Hypomorph, Inserted expressed sequence
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Allele
Gt(ROSA)26Sor<tm1(CAG-Bgeo,-MAPT/mTurquoise,-MAPT/tdTomato,-Gnas*)Kmov> | MGI:6764576
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Kiavash Movahedi
Allele Type: Targeted
Attribute String: Conditional ready, Dominant negative, Inserted expressed sequence, Reporter, RMCE-ready
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Strain
MGI:6145386 | C57BL/6-Tg(Or10j5-Gnas*Q227L,-EYFP)1Hsak/Hsak
Attribute String: mutant strain, coisogenic, transgenic
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Allele
Tg(Or10j5-Or6a2*D126R*R127D,-Gnas*Q227L,-ECFP*)1Hsak | MGI:7442219
Name: transgene insertion 1, Hitoshi Sakano
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
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Genotype
Genotype
Symbol: Gnas/Gnas Ren1/Ren1<+>
Background: involves: 129S6/SvEvTac * Black Swiss
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Braf/Braf Gnas/Gnas Tg(TPO-cre)1Shk/?
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/NCr
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas H2az2/H2az2<+>
Background: involves: 129S6/SvEvTac * C57BL/6J * CBA/J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gnas/Gnas Olig1/Olig1<+>
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Protein
Q9Z0F1
Organism: Mus musculus/domesticus
Length: 257  
Fragment?: false
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Protein
A6PW70
Organism: Mus musculus/domesticus
Length: 59  
Fragment?: true
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Protein
A6PW71
Organism: Mus musculus/domesticus
Length: 25  
Fragment?: true
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Publication
12438142 | -
 
First Author: Fischer-Colbrie R
Year: 2002
Journal: Ann N Y Acad Sci
Title: Neuroendocrine secretory protein 55: a novel marker for the constitutive secretory pathway.
Volume: 971
Pages: 317-22
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Protein Domain
IPR009434 | NESP55
Type: Family
Description: The imprinted GNAS cluster, located on chromosome 2 in mice and chromosome 20 in humans, contains transcripts that are maternally, paternally, and/or biallelically expressed. Neuroendocrine secretory protein 55 (NESP55) is encoded by an upstream exon of the GNAS1 gene, which is expressed exclusively from the maternal allele []. It is a neuroendocrine secretory granule protein originally identified by screening cDNA libraries from bovine chromaffin cells with antibody against secretogranin II []. It belongs to the granin family, whose members are involved in endocrine and neuronal secretory pathways [].NESP55 has been shown to act as biomarkers for endocrine and neuroendocrine tumours and implicated in cell growth []. It has been linked to pseudohypoparathyroidism type Ib (PHP-1b), an imprinted human disorder associated with methylation changes at one or several differentially methylated regions at the GNAS locus [].
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DO Term
DOID:4183 | pseudopseudohypoparathyroidism
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DO Term
DOID:0080222 | pseudohypoparathyroidism type 1B
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DO Term
DOID:0080053 | pseudohypoparathyroidism type 1A
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Strain
MGI:5308376 | B6CBACa-Tg(RP1-309F20*)48Kel/H
Attribute String: mutant stock, transgenic
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Allele
Or8a1<tm37(Or10j5*,Gnas*)Mom> | MGI:5489810
Name: olfactory receptor family 8 subfamily A member 1; targeted mutation 37, Peter Mombaerts
Allele Type: Targeted
Attribute String: Constitutively active, Inserted expressed sequence
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Strain
MGI:5788008 | B6;129P2-Or8a1<tm40(Gnas*)Mom>/MomJ
Attribute String: targeted mutation, mutant stock
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