|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 501 to 600 out of 1562 for Grb2

<< First    < Previous  |  Next >    Last >>
0.044s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
34345012 | J:311002
First Author: Su J
Year: 2021
Journal: Oncogene
Title: NSUN2-mediated RNA 5-methylcytosine promotes esophageal squamous cell carcinoma progression via LIN28B-dependent GRB2 mRNA stabilization.
Volume: 40
Issue: 39
Pages: 5814-5828
•
•
•
•
•
Publication
8959326 | J:200354
First Author: Vogel W
Year: 1996
Journal: Cell Growth Differ
Title: Multiple in vivo phosphorylated tyrosine phosphatase SHP-2 engages binding to Grb2 via tyrosine 584.
Volume: 7
Issue: 12
Pages: 1589-97
•
•
•
•
•
Publication
7523381 | J:159097
First Author: Tauchi T
Year: 1994
Journal: J Biol Chem
Title: The ubiquitously expressed Syp phosphatase interacts with c-kit and Grb2 in hematopoietic cells.
Volume: 269
Issue: 40
Pages: 25206-11
•
•
•
•
•
Publication
8183561 | J:18774
First Author: Borrello MG
Year: 1994
Journal: Oncogene
Title: The oncogenic versions of the Ret and Trk tyrosine kinases bind Shc and Grb2 adaptor proteins.
Volume: 9
Issue: 6
Pages: 1661-8
•
•
•
•
•
Publication
26188370 | J:226434
First Author: Burdon KP
Year: 2015
Journal: Diabetologia
Title: Genome-wide association study for sight-threatening diabetic retinopathy reveals association with genetic variation near the GRB2 gene.
Volume: 58
Issue: 10
Pages: 2288-97
•
•
•
•
•
Pathway
R-MMU-1963640 | GRB2 events in ERBB2 signaling
•
•
•
•
•
Pathway
R-MMU-179812 | GRB2 events in EGFR signaling
•
•
•
•
•
Publication
11238891 | J:67363
First Author: Dankort D
Year: 2001
Journal: Mol Cell Biol
Title: Grb2 and Shc adapter proteins play distinct roles in Neu (ErbB-2)-induced mammary tumorigenesis: implications for human breast cancer.
Volume: 21
Issue: 5
Pages: 1540-51
•
•
•
•
•
Gene
116743 | Sh3gl2
Type: gene
Organism: rat
•
•
•
•
•
Gene
81921 | Sh3gl3
Type: gene
Organism: rat
•
•
•
•
•
Gene
362801 | Garem2
Type: gene
Organism: rat
•
•
•
•
•
Gene
609858 | SH3GL3
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
611239 | SH3GL2
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
612505 | SH3GLB1
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
453602 | SH3GL3
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
465008 | SH3GL2
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
679154 | Garem1
Type: gene
Organism: rat
•
•
•
•
•
Gene
81922 | Sh3gl1
Type: gene
Organism: rat
•
•
•
•
•
Gene
456993 | SH3GLB1
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
468614 | GAREM1
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
470133 | GAB4
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
738129 | SH3GL1
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
743125 | GAREM2
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
485039 | SH3GL1
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
490496 | GAREM1
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
491306 | SH3GLB2
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
504750 | SH3GLB2
Type: gene
Organism: cattle
•
•
•
•
•
Gene
507330 | GAREM1
Type: gene
Organism: cattle
•
•
•
•
•
Gene
512450 | SH3GL2
Type: gene
Organism: cattle
•
•
•
•
•
Gene
512719 | SH3GL1
Type: gene
Organism: cattle
•
•
•
•
•
Gene
520311 | SH3GL3
Type: gene
Organism: cattle
•
•
•
•
•
Gene
533918 | SH3GLB1
Type: gene
Organism: cattle
•
•
•
•
•
Gene
783429 | GAREM2
Type: gene
Organism: cattle
•
•
•
•
•
Gene
100855723 | GAREM2
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
395201 | SH3GL3
Type: gene
Organism: chicken
•
•
•
•
•
Gene
395202 | SH3GL1
Type: gene
Organism: chicken
•
•
•
•
•
Gene
395203 | SH3GL2
Type: gene
Organism: chicken
•
•
•
•
•
Gene
417197 | SH3GLB2
Type: gene
Organism: chicken
•
•
•
•
•
Gene
421098 | GAREM1
Type: gene
Organism: chicken
•
•
•
•
•
Gene
424522 | SH3GLB1
Type: gene
Organism: chicken
•
•
•
•
•
Gene
770888 | GAREM2
Type: gene
Organism: chicken
•
•
•
•
•
Gene
776038 | SGIP1
Type: gene
Organism: chicken
•
•
•
•
•
Gene
394091 | sh3gl2a
Type: gene
Organism: zebrafish
•
•
•
•
•
Gene
794400 | sh3gl2b
Type: gene
Organism: zebrafish
•
•
•
•
•
Gene
100425935 | GAB4
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Gene
697774 | GAREM2
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Gene
712393 | SH3GLB1
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Gene
713393 | SH3GL2
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Gene
713899 | GAREM1
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Gene
714957 | SH3GL1
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Gene
716994 | SH3GLB2
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Gene
718542 | SH3GL3
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Gene
100493323 | garem1
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Gene
101730630 | garem2
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Gene
101733179 | garem2
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Gene
548519 | sh3glb2
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Gene
548826 | sh3glb1
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Gene
107976792 | SH3GLB2
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
101027291 | gab2.S
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Gene
101027312 | gab3.S
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Gene
108698390 | gab3.L
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Gene
108701658 | grap.L
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Gene
108703215 | grap.S
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Gene
108708757 | gab2.L
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Gene
108714401 | sh3glb1.L
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Gene
108714531 | grap2.L
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Gene
108715763 | grap2.S
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Gene
108718315 | garem2.S
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Gene
108719234 | garem1.L
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Gene
431942 | garem1.S
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Gene
443857 | sh3glb1.S
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Gene
446714 | sh3glb2.S
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Gene
447381 | garem2.L
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Gene
447598 | sh3glb2.L
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Gene
734245 | gab1.L
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Gene
734248 | gab1.S
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Publication
8400282 | J:266153
First Author: Damen JE
Year: 1993
Journal: Blood
Title: Erythropoietin stimulates the tyrosine phosphorylation of Shc and its association with Grb2 and a 145-Kd tyrosine phosphorylated protein.
Volume: 82
Issue: 8
Pages: 2296-303
•
•
•
•
•
Allele
Garem1<+> | MGI:3819411
 
Name: GRB2 associated regulator of MAPK1 subtype 1; wild type
Allele Type: Not Specified
•
•
•
•
•
Allele
Garem2<+> | MGI:3819413
 
Name: GRB2 associated regulator of MAPK1 subtype 2; wild type
Allele Type: Not Specified
•
•
•
•
•
Protein
Q60631
Organism: Mus musculus/domesticus
Length: 217  
Fragment?: false
•
•
•
•
•
Interaction Experiment
Nishida M (2001)
Description: Novel recognition mode between Vav and Grb2 SH3 domains.
•
•
•
•
•
Publication
23168613 | J:198253
First Author: Chonabayashi K
Year: 2013
Journal: Leukemia
Title: Direct binding of Grb2 has an important role in the development of myeloproliferative disease induced by ETV6/FLT3.
Volume: 27
Issue: 6
Pages: 1433-6
•
•
•
•
•
Publication
10567542 | J:58608
First Author: Rauh MJ
Year: 1999
Journal: Mol Cell Biol
Title: Accelerated mammary tumor development in mutant polyomavirus middle T transgenic mice expressing elevated levels of either the Shc or Grb2 adapter protein.
Volume: 19
Issue: 12
Pages: 8169-79
•
•
•
•
•
Publication
7522233 | J:200361
First Author: Welham MJ
Year: 1994
Journal: J Biol Chem
Title: Interleukin (IL)-3 and granulocyte/macrophage colony-stimulating factor, but not IL-4, induce tyrosine phosphorylation, activation, and association of SHPTP2 with Grb2 and phosphatidylinositol 3'-kinase.
Volume: 269
Issue: 38
Pages: 23764-8
•
•
•
•
•
Publication
7564569 | J:26716
First Author: Ghosh J
Year: 1995
Journal: Mech Ageing Dev
Title: Rapid tyrosine phosphorylation of Grb2 and Shc in T cells exposed to anti-CD3, anti-CD4, and anti-CD45 stimuli: differential effects of aging.
Volume: 80
Issue: 3
Pages: 171-87
•
•
•
•
•
Publication
31718706 | J:287781
First Author: Nishino T
Year: 2019
Journal: Mol Brain
Title: Behavioral analysis in mice deficient for GAREM2 (Grb2-associated regulator of Erk/MAPK subtype2) that is a subtype of highly expressing in the brain.
Volume: 12
Issue: 1
Pages: 94
•
•
•
•
•
Publication
19735729 | -
First Author: Ahmed Z
Year: 2010
Journal: Cell Signal
Title: Direct binding of Grb2 SH3 domain to FGFR2 regulates SHP2 function.
Volume: 22
Issue: 1
Pages: 23-33
•
•
•
•
•
Publication
24003223 | J:344920
First Author: Taniguchi T
Year: 2013
Journal: J Biol Chem
Title: A brain-specific Grb2-associated regulator of extracellular signal-regulated kinase (Erk)/mitogen-activated protein kinase (MAPK) (GAREM) subtype, GAREM2, contributes to neurite outgrowth of neuroblastoma cells by regulating Erk signaling.
Volume: 288
Issue: 41
Pages: 29934-42
•
•
•
•
•
Protein
Q60631-2
Organism: Mus musculus/domesticus
Length: 176  
Fragment?: false
•
•
•
•
•
Allele
Garem1<Gt(XT0544)Wtsi> | MGI:4332016
 
Name: GRB2 associated regulator of MAPK1 subtype 1; gene trap XT0544, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
•
•
•
•
•
Allele
Garem1<tm1a(EUCOMM)Wtsi> | MGI:4820333
Name: GRB2 associated regulator of MAPK1 subtype 1; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
•
•
•
•
•
Allele
Garem1<tm1e(EUCOMM)Wtsi> | MGI:4820351
Name: GRB2 associated regulator of MAPK1 subtype 1; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
•
•
•
•
•
Allele
Garem2<tm1.1Hkon> | MGI:6456656
Name: GRB2 associated regulator of MAPK1 subtype 2; targeted mutation 1.1, Hiroaki Konishi
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Allele
Garem2<tm1.2Hkon> | MGI:6456657
Name: GRB2 associated regulator of MAPK1 subtype 2; targeted mutation 1.2, Hiroaki Konishi
Allele Type: Targeted
Attribute String: Null/knockout
•
•
•
•
•
Allele
Garem1<em2Gpt> | MGI:7299439
Name: GRB2 associated regulator of MAPK1 subtype 1; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Allele
Garem1<em1Gpt> | MGI:7299440
Name: GRB2 associated regulator of MAPK1 subtype 1; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Allele
Garem1<em1.1Hkon> | MGI:7427461
Name: GRB2 associated regulator of MAPK1 subtype 1; endonuclease-mediated mutation 1, Hiroaki Konishi
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Interaction Experiment
Suen KL (1993)
Description: Molecular cloning of the mouse grb2 gene: differential interaction of the Grb2 adaptor protein with epidermal growth factor and nerve growth factor receptors.
•
•
•
•
•
Publication
17332510 | J:123565
First Author: Hayakawa-Yano Y
Year: 2007
Journal: Stem Cells
Title: Epidermal growth factor signaling mediated by grb2 associated binder1 is required for the spatiotemporally regulated proliferation of olig2-expressing progenitors in the embryonic spinal cord.
Volume: 25
Issue: 6
Pages: 1410-22
•
•
•
•
•
Publication
18778683 | -
First Author: McDonald CB
Year: 2008
Journal: Arch Biochem Biophys
Title: Structural basis of the differential binding of the SH3 domains of Grb2 adaptor to the guanine nucleotide exchange factor Sos1.
Volume: 479
Issue: 1
Pages: 52-62
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom