| Type |
Details |
Score |
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Allele |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Ophir D Klein |
| Allele Type: |
Targeted |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Allele |
| Name: |
lysine (K)-specific methyltransferase 2A; targeted mutation 1, Stanley J Korsmeyer |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2; gene trap 1, Srecko Gajovic |
| Allele Type: |
Gene trapped |
| Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kapuralin K |
| Year: |
2015 |
| Journal: |
Mol Cell Neurosci |
| Title: |
STAM2, a member of the endosome-associated complex ESCRT-0 is highly expressed in neurons. |
| Volume: |
67 |
|
| Pages: |
104-15 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
gene trap, mutant strain |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kapuralin K |
| Year: |
2012 |
| Journal: |
Anat Rec (Hoboken) |
| Title: |
Neurons and a subset of interstitial cells of Cajal in the enteric nervous system highly express Stam2 gene. |
| Volume: |
295 |
| Issue: |
1 |
| Pages: |
113-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Furić Cunko V |
| Year: |
2008 |
| Journal: |
Coll Antropol |
| Title: |
Expression pattern and functional analysis of mouse Stam2 in the olfactory system. |
| Volume: |
32 Suppl 1 |
|
| Pages: |
59-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Curlin M |
| Year: |
2012 |
| Journal: |
Gene Expr Patterns |
| Title: |
Stam2 expression pattern during embryo development. |
| Volume: |
12 |
| Issue: |
1-2 |
| Pages: |
68-76 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Stam2/Stam2 |
| Background: |
B6NCrl.Cg-Stam2 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Stam2/Stam2<+> |
| Background: |
B6NCrl.Cg-Stam2 |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim SY |
| Year: |
2007 |
| Journal: |
J Biol Chem |
| Title: |
Developmental regulation of Eed complex composition governs a switch in global histone modification in brain. |
| Volume: |
282 |
| Issue: |
13 |
| Pages: |
9962-72 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gupta S |
| Year: |
2010 |
| Journal: |
J Neurosci |
| Title: |
Histone methylation regulates memory formation. |
| Volume: |
30 |
| Issue: |
10 |
| Pages: |
3589-99 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hanson RD |
| Year: |
1999 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development. |
| Volume: |
96 |
| Issue: |
25 |
| Pages: |
14372-7 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
targeted mutation, mutant stock |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jude CD |
| Year: |
2007 |
| Journal: |
Cell Stem Cell |
| Title: |
Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors. |
| Volume: |
1 |
| Issue: |
3 |
| Pages: |
324-37 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dorrance AM |
| Year: |
2008 |
| Journal: |
Blood |
| Title: |
The Mll partial tandem duplication: differential, tissue-specific activity in the presence or absence of the wild-type allele. |
| Volume: |
112 |
| Issue: |
6 |
| Pages: |
2508-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huang HS |
| Year: |
2007 |
| Journal: |
J Neurosci |
| Title: |
Prefrontal dysfunction in schizophrenia involves mixed-lineage leukemia 1-regulated histone methylation at GABAergic gene promoters. |
| Volume: |
27 |
| Issue: |
42 |
| Pages: |
11254-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dorrance AM |
| Year: |
2006 |
| Journal: |
J Clin Invest |
| Title: |
Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations. |
| Volume: |
116 |
| Issue: |
10 |
| Pages: |
2707-16 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Takeda S |
| Year: |
2013 |
| Journal: |
J Clin Invest |
| Title: |
HGF-MET signals via the MLL-ETS2 complex in hepatocellular carcinoma. |
| Volume: |
123 |
| Issue: |
7 |
| Pages: |
3154-65 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yu BD |
| Year: |
1998 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis. |
| Volume: |
95 |
| Issue: |
18 |
| Pages: |
10632-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu H |
| Year: |
2010 |
| Journal: |
Nature |
| Title: |
Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint. |
| Volume: |
467 |
| Issue: |
7313 |
| Pages: |
343-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang P |
| Year: |
2009 |
| Journal: |
Mol Cell Biol |
| Title: |
Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II. |
| Volume: |
29 |
| Issue: |
22 |
| Pages: |
6074-85 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Kmt2a/Kmt2a |
| Background: |
involves: 129S2/SvPas * C3H * C57BL/6 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Kmt2a/Kmt2a<+> |
| Background: |
involves: 129S2/SvPas * C3H * C57BL/6 |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Kmt2a/Kmt2a |
| Background: |
involves: 129S2/SvPas * C57BL/6 * FVB/N |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Kmt2a/Kmt2a |
| Background: |
involves: 129S2/SvPas * CD-1 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Bmi1/Bmi1 Kmt2a/Kmt2a<+> |
| Background: |
involves: 129P2/OlaHsd * 129S2/SvPas * C3H * C57BL/6 * FVB |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Allele |
| Name: |
homeobox C8; targeted mutation 3, Jeh-Ping Liu |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
72
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
136
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
This domain constitutes the N-terminal of the paralogous homeobox proteins HoxA9, HoxB9, HoxC9 and HoxD9. The N-terminal region is thought to act as a transcription activation region. Activation may be by interaction with proteins such as Btg proteins, which are thought to recruit a multi-protein Ccr4-like complex []. |
|
•
•
•
•
•
|
| Allele |
| Name: |
homeobox C8; targeted mutation 4, Jeh-Ping Liu |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gajović S |
| Year: |
1998 |
| Journal: |
Exp Cell Res |
| Title: |
Genes expressed after retinoic acid-mediated differentiation of embryoid bodies are likely to be expressed during embryo development. |
| Volume: |
242 |
| Issue: |
1 |
| Pages: |
138-43 |
|
•
•
•
•
•
|
| Allele |
| Name: |
homeobox C cluster; targeted mutation 1.1, S Steven Potter |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Hoxc8/Hoxc8<+> |
| Background: |
involves: 129S1/Sv * C57BL/6 |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Hoxc8/Hoxc8 |
| Background: |
involves: 129S1/Sv * C57BL/6 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Hoxc8/Hoxc8 |
| Background: |
involves: 129S1/Sv * C57BL/6 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor Gli1/Gli1<+> |
| Background: |
involves: 129S6/SvEvTac |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Hoxa/Hoxa Hoxc/Hoxc |
| Background: |
involves: 129 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Hoxa/Hoxa<+> Hoxc/Hoxc |
| Background: |
involves: 129 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Hoxa/Hoxa Hoxc/Hoxc<+> |
| Background: |
involves: 129 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Prévôt D |
| Year: |
2000 |
| Journal: |
J Biol Chem |
| Title: |
The leukemia-associated protein Btg1 and the p53-regulated protein Btg2 interact with the homeoprotein Hoxb9 and enhance its transcriptional activation. |
| Volume: |
275 |
| Issue: |
1 |
| Pages: |
147-53 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Drake KA |
| Year: |
2018 |
| Journal: |
Sci Rep |
| Title: |
Disruption of Hox9,10,11 function results in cellular level lineage infidelity in the kidney. |
| Volume: |
8 |
| Issue: |
1 |
| Pages: |
6306 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Hoxa/Hoxa<+> Hoxc/Hoxc<+> Hoxd/Hoxd<+> |
| Background: |
involves: 129 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Hoxa/Hoxa<+> Hoxc/Hoxc<+> Hoxd/Hoxd<+> |
| Background: |
involves: 129 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mucenski ML |
| Year: |
2019 |
| Journal: |
Sci Rep |
| Title: |
Single cell RNA-seq study of wild type and Hox9,10,11 mutant developing uterus. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
4557 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Biehs B |
| Year: |
2013 |
| Journal: |
Nat Cell Biol |
| Title: |
BMI1 represses Ink4a/Arf and Hox genes to regulate stem cells in the rodent incisor. |
| Volume: |
15 |
| Issue: |
7 |
| Pages: |
846-52 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
260
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
250
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
271
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
339
 |
| Fragment?: |
false |
|
•
•
•
•
•
|