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Search results 501 to 600 out of 3442 for Hprt

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Hits by Pathway

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Type Details Score
Allele
Krt6a<tm1Der> | MGI:2386313
Name: keratin 6A; targeted mutation 1, Dennis R Roop
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:3849022 | B6.129P2-Gjd2<tm1Kwi>/Cnrm
Attribute String: targeted mutation, mutant strain, congenic
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Publication
11487627 | J:70839
First Author: Güldenagel M
Year: 2001
Journal: J Neurosci
Title: Visual transmission deficits in mice with targeted disruption of the gap junction gene connexin36.
Volume: 21
Issue: 16
Pages: 6036-44
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Publication
22056383 | J:184025
First Author: Klee P
Year: 2011
Journal: J Clin Invest
Title: Connexins protect mouse pancreatic β cells against apoptosis.
Volume: 121
Issue: 12
Pages: 4870-9
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Publication
22771400 | J:206560
 
First Author: Nagy JI
Year: 2012
Journal: Brain Res
Title: Evidence for connexin36 localization at hippocampal mossy fiber terminals suggesting mixed chemical/electrical transmission by granule cells.
Volume: 1487
Pages: 107-22
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Publication
16101742 | J:100930
First Author: Striedinger K
Year: 2005
Journal: Eur J Neurosci
Title: Loss of connexin36 increases retinal cell vulnerability to secondary cell loss.
Volume: 22
Issue: 3
Pages: 605-16
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Publication
15919802 | J:105190
First Author: Ravier MA
Year: 2005
Journal: Diabetes
Title: Loss of connexin36 channels alters beta-cell coupling, islet synchronization of glucose-induced Ca2+ and insulin oscillations, and basal insulin release.
Volume: 54
Issue: 6
Pages: 1798-807
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Publication
15617784 | J:95216
First Author: Frisch C
Year: 2005
Journal: Behav Brain Res
Title: Stimulus complexity dependent memory impairment and changes in motor performance after deletion of the neuronal gap junction protein connexin36 in mice.
Volume: 157
Issue: 1
Pages: 177-85
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Publication
15924862 | J:99856
First Author: Christie JM
Year: 2005
Journal: Neuron
Title: Connexin36 mediates spike synchrony in olfactory bulb glomeruli.
Volume: 46
Issue: 5
Pages: 761-72
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Publication
12064624 | J:117402
First Author: Calabrese A
Year: 2001
Journal: Cell Commun Adhes
Title: Cx36 and the function of endocrine pancreas.
Volume: 8
Issue: 4-6
Pages: 387-91
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Publication
12805309 | J:83883
First Author: De Zeeuw CI
Year: 2003
Journal: J Neurosci
Title: Deformation of network connectivity in the inferior olive of connexin 36-deficient mice is compensated by morphological and electrophysiological changes at the single neuron level.
Volume: 23
Issue: 11
Pages: 4700-11
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Publication
12042356 | J:105937
First Author: Maier N
Year: 2002
Journal: J Physiol
Title: Reduction of high-frequency network oscillations (ripples) and pathological network discharges in hippocampal slices from connexin 36-deficient mice.
Volume: 541
Issue: Pt 2
Pages: 521-8
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Publication
17395748 | J:122093
First Author: Speier S
Year: 2007
Journal: Diabetes
Title: Cx36-mediated coupling reduces beta-cell heterogeneity, confines the stimulating glucose concentration range, and affects insulin release kinetics.
Volume: 56
Issue: 4
Pages: 1078-86
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Publication
12738878 | J:83624
First Author: Chirala SS
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Fatty acid synthesis is essential in embryonic development: fatty acid synthase null mutants and most of the heterozygotes die in utero.
Volume: 100
Issue: 11
Pages: 6358-63
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Publication
26474913 | J:229098
 
First Author: Chung L
Year: 2015
Journal: Brain Res
Title: Parental origin impairment of synaptic functions and behaviors in cytoplasmic FMRP interacting protein 1 (Cyfip1) deficient mice.
Volume: 1629
Pages: 340-50
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Allele
Guca2a<tm1Mcoh> | MGI:2447172
Name: guanylate cyclase activator 2a (guanylin); targeted mutation 1, Mitchell B Cohen
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Wnt3<tm2Brd> | MGI:2450289
Name: wingless-type MMTV integration site family, member 3; targeted mutation 2, Allan Bradley
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Hprt1<tm1(ACTB-Epor)Unc> | MGI:2450106
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, University of North Carolina
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Strain
MGI:7714925 | STOCK Lipa<tm1Hodu>/CyanJ
Attribute String: targeted mutation, mutant stock
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Publication
9700186 | J:49674
First Author: Du H
Year: 1998
Journal: Hum Mol Genet
Title: Targeted disruption of the mouse lysosomal acid lipase gene: long-term survival with massive cholesteryl ester and triglyceride storage.
Volume: 7
Issue: 9
Pages: 1347-54
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Publication
29599133 | J:285128
First Author: Bowden KL
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: LAL (Lysosomal Acid Lipase) Promotes Reverse Cholesterol Transport In Vitro and In Vivo.
Volume: 38
Issue: 5
Pages: 1191-1201
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Publication
33159889 | J:304380
First Author: Ding X
Year: 2021
Journal: Am J Pathol
Title: Lysosomal Acid Lipase Deficiency Controls T- and B-Regulatory Cell Homeostasis in the Lymph Nodes of Mice with Human Cancer Xenotransplants.
Volume: 191
Issue: 2
Pages: 353-367
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Publication
22383970 | J:224048
First Author: Yan C
Year: 2012
Journal: PLoS One
Title: Gene profile of myeloid-derived suppressive cells from the bone marrow of lysosomal acid lipase knock-out mice.
Volume: 7
Issue: 2
Pages: e30701
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Publication
38160938 | J:344696
 
First Author: Akhmetshina A
Year: 2024
Journal: Mol Metab
Title: Loss of lysosomal acid lipase results in mitochondrial dysfunction and fiber switch in skeletal muscles of mice.
Volume: 79
Pages: 101869
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Publication
24287405 | J:208075
First Author: Ding X
Year: 2014
Journal: Am J Pathol
Title: Critical role of the mTOR pathway in development and function of myeloid-derived suppressor cells in lal-/- mice.
Volume: 184
Issue: 2
Pages: 397-408
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Publication
33113360 | J:312147
First Author: Nguyen HD
Year: 2020
Journal: Cell Rep
Title: Lysosomal Acid Lipase Is Required for Donor T Cells to Induce Graft-versus-Host Disease.
Volume: 33
Issue: 4
Pages: 108316
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Publication
25147230 | J:227757
First Author: Aqul A
Year: 2014
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Hepatic entrapment of esterified cholesterol drives continual expansion of whole body sterol pool in lysosomal acid lipase-deficient mice.
Volume: 307
Issue: 8
Pages: G836-47
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Publication
16127159 | J:100712
First Author: Lian X
Year: 2005
Journal: Am J Pathol
Title: Neutral lipids and peroxisome proliferator-activated receptor-{gamma} control pulmonary gene expression and inflammation-triggered pathogenesis in lysosomal acid lipase knockout mice.
Volume: 167
Issue: 3
Pages: 813-21
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Publication
14644759 | J:101217
First Author: Lian X
Year: 2004
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Lysosomal acid lipase deficiency causes respiratory inflammation and destruction in the lung.
Volume: 286
Issue: 4
Pages: L801-7
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Publication
26625314 | J:309646
First Author: Zhao T
Year: 2016
Journal: Oncotarget
Title: Critical role of PPARγ in myeloid-derived suppressor cell-stimulated cancer cell proliferation and metastasis.
Volume: 7
Issue: 2
Pages: 1529-43
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Publication
24837159 | J:212316
First Author: Sun Y
Year: 2014
Journal: Mol Genet Metab
Title: Reversal of advanced disease in lysosomal acid lipase deficient mice: a model for lysosomal acid lipase deficiency disease.
Volume: 112
Issue: 3
Pages: 229-41
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Publication
11487567 | J:71200
First Author: Du H
Year: 2001
Journal: Hum Mol Genet
Title: Enzyme therapy for lysosomal acid lipase deficiency in the mouse.
Volume: 10
Issue: 16
Pages: 1639-48
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Publication
19179613 | J:146658
First Author: Qu P
Year: 2009
Journal: Am J Pathol
Title: Critical roles of lysosomal acid lipase in T cell development and function.
Volume: 174
Issue: 3
Pages: 944-56
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Publication
34685599 | J:312439
 
First Author: Sachdev V
Year: 2021
Journal: Cells
Title: Impaired Bile Acid Metabolism and Gut Dysbiosis in Mice Lacking Lysosomal Acid Lipase.
Volume: 10
Issue: 10
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Publication
33838322 | J:353248
 
First Author: Helderman RC
Year: 2021
Journal: Bone
Title: Loss of function of lysosomal acid lipase (LAL) profoundly impacts osteoblastogenesis and increases fracture risk in humans.
Volume: 148
Pages: 115946
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Publication
27354281 | J:236160
First Author: Grumet L
Year: 2016
Journal: J Biol Chem
Title: Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover.
Volume: 291
Issue: 34
Pages: 17977-87
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Publication
29374543 | J:261851
First Author: Duta-Mare M
Year: 2018
Journal: Biochim Biophys Acta
Title: Lysosomal acid lipase regulates fatty acid channeling in brown adipose tissue to maintain thermogenesis.
Volume: 1863
Issue: 4
Pages: 467-478
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Publication
11290820 | J:68812
First Author: Du H
Year: 2001
Journal: J Lipid Res
Title: Lysosomal acid lipase-deficient mice: depletion of white and brown fat, severe hepatosplenomegaly, and shortened life span.
Volume: 42
Issue: 4
Pages: 489-500
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Publication
20348241 | J:160762
First Author: Qu P
Year: 2010
Journal: Am J Pathol
Title: Critical roles of lysosomal acid lipase in myelopoiesis.
Volume: 176
Issue: 5
Pages: 2394-404
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Publication
28402950 | J:275041
First Author: Schlager S
Year: 2017
Journal: Oncotarget
Title: Lysosomal lipid hydrolysis provides substrates for lipid mediator synthesis in murine macrophages.
Volume: 8
Issue: 25
Pages: 40037-40051
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Publication
24882582 | J:221270
First Author: Zhao T
Year: 2015
Journal: Oncogene
Title: Activation of mTOR pathway in myeloid-derived suppressor cells stimulates cancer cell proliferation and metastasis in lal(-/-) mice.
Volume: 34
Issue: 15
Pages: 1938-48
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Publication
24370824 | J:211848
First Author: Chuang JC
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Ezetimibe markedly attenuates hepatic cholesterol accumulation and improves liver function in the lysosomal acid lipase-deficient mouse, a model for cholesteryl ester storage disease.
Volume: 443
Issue: 3
Pages: 1073-7
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Allele
Atp1a1<tm1Ling> | MGI:2451290
Name: ATPase, Na+/K+ transporting, alpha 1 polypeptide; targeted mutation 1, Jerry B Lingrel
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Atp1a2<tm2Ling> | MGI:2451291
Name: ATPase, Na+/K+ transporting, alpha 2 polypeptide; targeted mutation 2, Jerry B Lingrel
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
38348353 | J:353413
 
First Author: Berdaweel IA
Year: 2023
Journal: Front Pharmacol
Title: Iron scavenging and suppression of collagen cross-linking underlie antifibrotic effects of carnosine in the heart with obesity.
Volume: 14
Pages: 1275388
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Publication
19744930 | J:156336
First Author: Liang H
Year: 2009
Journal: J Biol Chem
Title: Short form glutathione peroxidase 4 is the essential isoform required for survival and somatic mitochondrial functions.
Volume: 284
Issue: 45
Pages: 30836-44
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Publication
17895430 | J:129984
First Author: Ran Q
Year: 2007
Journal: J Gerontol A Biol Sci Med Sci
Title: Reduction in glutathione peroxidase 4 increases life span through increased sensitivity to apoptosis.
Volume: 62
Issue: 9
Pages: 932-42
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Publication
30226473 | J:271218
First Author: Anderson EJ
Year: 2018
Journal: J Clin Invest
Title: A carnosine analog mitigates metabolic disorders of obesity by reducing carbonyl stress.
Volume: 128
Issue: 12
Pages: 5280-5293
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Publication
16246897 | J:116838
First Author: Scimeca MS
Year: 2005
Journal: Exp Biol Med (Maywood)
Title: Effects of gpx4 haploid insufficiency on GPx4 activity, selenium concentration, and paraquat-induced protein oxidation in murine tissues.
Volume: 230
Issue: 10
Pages: 709-14
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Publication
26042203 | J:297698
First Author: Katunga LA
Year: 2015
Journal: Mol Metab
Title: Obesity in a model of gpx4 haploinsufficiency uncovers a causal role for lipid-derived aldehydes in human metabolic disease and cardiomyopathy.
Volume: 4
Issue: 6
Pages: 493-506
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Allele
Rtn4<tm3Matl> | MGI:2661203
Name: reticulon 4; targeted mutation 3, Marc Tessier-Lavigne
Allele Type: Targeted
Attribute String: Conditional ready, Hypomorph, Reporter
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Publication
21940816 | J:191910
First Author: Bundesmann MM
Year: 2012
Journal: Am J Respir Cell Mol Biol
Title: Role of urokinase plasminogen activator receptor-associated protein in mouse lung.
Volume: 46
Issue: 2
Pages: 233-9
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Publication
24663959 | J:215062
First Author: Rohani MG
Year: 2014
Journal: PLoS One
Title: uPARAP function in cutaneous wound repair.
Volume: 9
Issue: 3
Pages: e92660
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Publication
21768090 | J:309615
First Author: Jürgensen HJ
Year: 2011
Journal: J Biol Chem
Title: A novel functional role of collagen glycosylation: interaction with the endocytic collagen receptor uparap/ENDO180.
Volume: 286
Issue: 37
Pages: 32736-48
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Publication
18639653 | J:138322
First Author: Smith L
Year: 2008
Journal: Gene Expr Patterns
Title: uPARAP expression during murine lung development.
Volume: 8
Issue: 7-8
Pages: 486-93
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Publication
22294280 | J:307473
First Author: Madsen DH
Year: 2012
Journal: J Pathol
Title: Endocytic collagen degradation: a novel mechanism involved in protection against liver fibrosis.
Volume: 227
Issue: 1
Pages: 94-105
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Publication
30518756 | J:267963
First Author: Durré T
Year: 2018
Journal: Nat Commun
Title: uPARAP/Endo180 receptor is a gatekeeper of VEGFR-2/VEGFR-3 heterodimerisation during pathological lymphangiogenesis.
Volume: 9
Issue: 1
Pages: 5178
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Allele
Gucy2c<tm1Gian> | MGI:2678361
Name: guanylate cyclase 2c; targeted mutation 1, Ralph A Giannella
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Rho<tm2(RHO/GFP)Jhw> | MGI:3046186
Name: rhodopsin; targeted mutation 2, John H Wilson
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence, Null/knockout, Reporter
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Allele
Hprt1<tm1Dhm> | MGI:3050087
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, David H MacLennan
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Allele
Tbxas1<tm1Swl> | MGI:3052866
Name: thromboxane A synthase 1, platelet; targeted mutation 1, Shu-Wha Lin
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Apc<tm1Cip> | MGI:3513416
Name: APC, WNT signaling pathway regulator; targeted mutation 1, Christine Perret
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:6144801 | STOCK Apc<tm2.1Cip>/GvnRbrc
Attribute String: mutant stock, targeted mutation
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Strain
MGI:5498526 | STOCK Apc<tm2.1Cip>/Orl
Attribute String: mutant stock, targeted mutation
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Publication
7708733 | J:24158
First Author: Stacey A
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Lactation is disrupted by alpha-lactalbumin deficiency and can be restored by human alpha-lactalbumin gene replacement in mice.
Volume: 92
Issue: 7
Pages: 2835-9
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Strain
MGI:3589463 | B6.129S7-Del(11Cops3-Rnf112)1Jrl/J
Attribute String: congenic, chromosome aberration, deletion, mutant strain, targeted mutation
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Allele
Rr70<tm1Alb> | MGI:3617404
 
Name: regulatory region 70; targeted mutation 4, Arthur L Beaudet
Allele Type: Targeted
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Allele
Snrpn<tm5Alb> | MGI:3617407
Name: small nuclear ribonucleoprotein N; targeted mutation 5, Arthur L Beaudet
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Ufd1<tm1Bld> | MGI:3640091
Name: ubiquitin recognition factor in ER-associated degradation 1; targeted mutation 1, Antonio Baldini
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Csn3<tm1Kuma> | MGI:3640309
Name: casein kappa; targeted mutation 1, Satish Kumar
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Sele<tm2Alb> | MGI:3767067
Name: selectin, endothelial cell; targeted mutation 2, Arthur L Beaudet
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Dgcr2<tm1Aam> | MGI:3798958
Name: DiGeorge syndrome critical region gene 2; targeted mutation 1, Alea A Mills
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Hira<tm1Aam> | MGI:3798961
Name: histone cell cycle regulator; targeted mutation 1, Alea A Mills
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Tmprss6<tm1Otin> | MGI:3809291
Name: transmembrane serine protease 6; targeted mutation 1, Carlos Lopez-Otin
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
F2<tm1Jld> | MGI:3831686
Name: coagulation factor II; targeted mutation 1, Jay L Degen
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Tg(Cdx1-cre)23Kem | MGI:3841474
Name: transgene insertion 23, Rolf Kemler
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(FCER1A)1Bhk | MGI:3846551
Name: transgene insertion 1, Beverly H Koller
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Prnp<tm1Lnq> | MGI:4412098
 
Name: prion protein; targeted mutation 1, Susan Lindquist
Allele Type: Targeted
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Allele
TgTn(itol2-CAG-GFP)1Dla | MGI:4413570
Name: transgenic transposon concatemer 1, David A Largaespada
Allele Type: Transgenic
Attribute String: Transposon concatemer
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Allele
Abcg1<tm1Yah> | MGI:4421206
 
Name: ATP binding cassette subfamily G member 1; targeted mutation 1, Yann Herault
Allele Type: Targeted
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Allele
Is(17B1)1Yah | MGI:4431358
Name: insertion, Chr 17, cytogenetic band B1, Yann Herault 1
Allele Type: Targeted
Attribute String: Reporter
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Allele
F9<tm3Dws> | MGI:4847605
 
Name: coagulation factor IX; targeted mutation 3, Darrel W Stafford
Allele Type: Targeted
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Allele
Prmt2<tm1Yah> | MGI:4868409
 
Name: protein arginine N-methyltransferase 2; targeted mutation 1, Yann Herault
Allele Type: Targeted
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Strain
MGI:5318269 | B6.129P2-Cstb<tm1Yah>
Attribute String: congenic, mutant strain, targeted mutation
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Allele
F2<tm2Jld> | MGI:5140722
 
Name: coagulation factor II; targeted mutation 2, Jay L Degen
Allele Type: Targeted
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Publication
22056776 | J:180185
First Author: Lynch MD
Year: 2012
Journal: EMBO J
Title: An interspecies analysis reveals a key role for unmethylated CpG dinucleotides in vertebrate Polycomb complex recruitment.
Volume: 31
Issue: 2
Pages: 317-29
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Strain
MGI:5524246 | FVB.129S7-Del(13)1Mgld
Attribute String: congenic, deletion, chemically induced mutation
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Publication
23785296 | J:199158
First Author: Smits BM
Year: 2013
Journal: PLoS Genet
Title: The gene desert mammary carcinoma susceptibility locus Mcs1a regulates Nr2f1 modifying mammary epithelial cell differentiation and proliferation.
Volume: 9
Issue: 6
Pages: e1003549
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Allele
Rho<tm1.1(RHO*)Akgr> | MGI:5550062
 
Name: rhodopsin; targeted mutation 1.1, Alecia K Gross
Allele Type: Targeted
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Allele
Hprt1<tm1(CAG-NPM1*)Pgp> | MGI:5585588
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Pier Giuseppe Pelicci
Allele Type: Targeted
Attribute String: Conditional ready
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Publication
26039448 | J:344143
First Author: Varanita T
Year: 2015
Journal: Cell Metab
Title: The OPA1-dependent mitochondrial cristae remodeling pathway controls atrophic, apoptotic, and ischemic tissue damage.
Volume: 21
Issue: 6
Pages: 834-44
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Strain
MGI:6159859 | B6;129P2-Vmn2r1<tm1Mom>/MomJ
Attribute String: mutant strain, targeted mutation
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Allele
Hprt1<tm1(CAG-Glra3*)Jcme> | MGI:5608589
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Jochen C Meier
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence
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Strain
MGI:5661506 | B6.129P2-Hspbp1<tm1Jhoh>
Attribute String: targeted mutation, mutant strain, congenic
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Publication
21283720 | J:224282
First Author: Kettern N
Year: 2011
Journal: PLoS One
Title: The Hsc/Hsp70 co-chaperone network controls antigen aggregation and presentation during maturation of professional antigen presenting cells.
Volume: 6
Issue: 1
Pages: e16398
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Publication
24899640 | J:216246
First Author: Rogon C
Year: 2014
Journal: Mol Biol Cell
Title: HSP70-binding protein HSPBP1 regulates chaperone expression at a posttranslational level and is essential for spermatogenesis.
Volume: 25
Issue: 15
Pages: 2260-71
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Strain
MGI:5751468 | B6J.129S7-Cyfip1<tm1Yhj>
Attribute String: congenic, targeted mutation, mutant strain
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Allele
Hprt1<tm3(Zfy2*)Jtu> | MGI:6149948
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 3, James Turner
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Allele
Hprt1<tm1(GRN)Blrl> | MGI:6512847
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Blair R Leavitt
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Hprt1<tm368(NR2E1*,bEMS114)Ems> | MGI:6514877
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 368, Elizabeth M Simpson
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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