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Search results 501 to 600 out of 633 for Icos

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Type Details Score
Publication
31123085 | J:280051
First Author: Zhu Y
Year: 2019
Journal: J Exp Med
Title: The E3 ligase VHL promotes follicular helper T cell differentiation via glycolytic-epigenetic control.
Volume: 216
Issue: 7
Pages: 1664-1681
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Publication
27637146 | J:254812
First Author: Zeng H
Year: 2016
Journal: Immunity
Title: mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation.
Volume: 45
Issue: 3
Pages: 540-554
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Publication
23812097 | J:201798
First Author: Kang SG
Year: 2013
Journal: Nat Immunol
Title: MicroRNAs of the miR-17∼92 family are critical regulators of T(FH) differentiation.
Volume: 14
Issue: 8
Pages: 849-57
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Publication
33637761 | J:304853
First Author: Yao Y
Year: 2021
Journal: Nat Commun
Title: METTL3-dependent m6A modification programs T follicular helper cell differentiation.
Volume: 12
Issue: 1
Pages: 1333
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Publication
16443792 | J:106844
First Author: Lundholm M
Year: 2006
Journal: Diabetes
Title: Defective induction of CTLA-4 in the NOD mouse is controlled by the NOD allele of Idd3/IL-2 and a novel locus (Ctex) telomeric on chromosome 1.
Volume: 55
Issue: 2
Pages: 538-44
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Publication
16177065 | J:118994
First Author: Fields ML
Year: 2005
Journal: J Immunol
Title: CD4+ CD25+ regulatory T cells inhibit the maturation but not the initiation of an autoantibody response.
Volume: 175
Issue: 7
Pages: 4255-64
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Publication
29398449 | J:257764
First Author: Cortes JR
Year: 2018
Journal: Cancer Cell
Title: RHOA G17V Induces T Follicular Helper Cell Specification and Promotes Lymphomagenesis.
Volume: 33
Issue: 2
Pages: 259-273.e7
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Publication
28228556 | J:252233
First Author: Zhang Z
Year: 2017
Journal: J Immunol
Title: Activation and Functional Specialization of Regulatory T Cells Lead to the Generation of Foxp3 Instability.
Volume: 198
Issue: 7
Pages: 2612-2625
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Publication
28290453 | J:244924
 
First Author: Downs-Canner S
Year: 2017
Journal: Nat Commun
Title: Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells.
Volume: 8
Pages: 14649
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Publication
25743066 | J:221898
 
First Author: Pratama A
Year: 2015
Journal: Nat Commun
Title: MicroRNA-146a regulates ICOS-ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres.
Volume: 6
Pages: 6436
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Publication
34471108 | J:310403
First Author: Hoefig KP
Year: 2021
Journal: Nat Commun
Title: Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation.
Volume: 12
Issue: 1
Pages: 5208
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Publication
23242415 | J:192538
First Author: Sage PT
Year: 2013
Journal: Nat Immunol
Title: The receptor PD-1 controls follicular regulatory T cells in the lymph nodes and blood.
Volume: 14
Issue: 2
Pages: 152-61
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Publication
24138884 | J:208729
First Author: He J
Year: 2013
Journal: Immunity
Title: Circulating precursor CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.
Volume: 39
Issue: 4
Pages: 770-81
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Publication
26146074 | J:224845
First Author: Sage PT
Year: 2015
Journal: Cell Rep
Title: Defective TFH Cell Function and Increased TFR Cells Contribute to Defective Antibody Production in Aging.
Volume: 12
Issue: 2
Pages: 163-71
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Publication
28490441 | J:249056
First Author: Taylor S
Year: 2017
Journal: J Exp Med
Title: PD-1 regulates KLRG1+ group 2 innate lymphoid cells.
Volume: 214
Issue: 6
Pages: 1663-1678
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Publication
34752418 | J:329521
 
First Author: Borges TJ
Year: 2021
Journal: JCI Insight
Title: Overexpression of PD-1 on T cells promotes tolerance in cardiac transplantation via ICOS-dependent mechanisms.
Volume: 6
Issue: 24
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Publication
36820828 | J:340867
 
First Author: Seth A
Year: 2023
Journal: J Exp Med
Title: AP-1-independent NFAT signaling maintains follicular T cell function in infection and autoimmunity.
Volume: 220
Issue: 5
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Protein Coding Gene
MGI:1098772 | Pik3r2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
O08908
Organism: Mus musculus/domesticus
Length: 722  
Fragment?: false
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Allele
Prdm1<tm1Clme> | MGI:3605621
Name: PR domain containing 1, with ZNF domain; targeted mutation 1, Kathryn Calame
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Genotype
Genotype
Symbol: Prdm1/Prdm1 Tg(Itgax-cre)1-1Reiz/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Protein Coding Gene
MGI:3611233 | Tox2
Type: protein_coding_gene
Organism: mouse, laboratory
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Allele
Batf<tm1.1Ejt> | MGI:4459733
Name: basic leucine zipper transcription factor, ATF-like; targeted mutation 1.1, Elizabeth J Taparowsky
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Pik3cd<tm2.1Tnr> | MGI:4850049
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; targeted mutation 2.1, Martin Turner
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Bcl6<tm1.1Mtto> | MGI:5461311
Name: B cell leukemia/lymphoma 6; targeted mutation 1.1, Toshitada Takemori
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Bcl6<tm1.1Meln> | MGI:5502178
Name: B cell leukemia/lymphoma 6; targeted mutation 1.1, Ari Melnick
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Allele
Tnfsf15<tm1Hluo> | MGI:5563219
Name: tumor necrosis factor (ligand) superfamily, member 15; targeted mutation 1, Hongyu Luo
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Ikzf4<tm1Djr> | MGI:6467011
Name: IKAROS family zinc finger 4; targeted mutation 1, Derrick Rossi
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Rinl<tm1.1Boun> | MGI:7623983
Name: Ras and Rab interactor-like; targeted mutation 1.1, Nicole Boucheron
Allele Type: Targeted
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Pik3cd/Pik3cd Tnfrsf4/Tnfrsf4<+>
Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bcl6/Bcl6 Tg(Cd4-cre)1Cwi/?
Background: involves: C57BL/6 * C57BL/6JJcl * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rnaseh2b/Rnaseh2b<+> Tlr7/Tlr7<+>
Background: C57BL/6NCrl-Rnaseh2b Tlr7
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rinl/Rinl
Background: B6.Cg-Rinl
Zygosity: hm
Has Mutant Allele: true
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Protein Coding Gene
MGI:97583 | Pik3r1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1206581 | Pik3ca
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P26450
Organism: Mus musculus/domesticus
Length: 724  
Fragment?: false
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Protein
P42337
Organism: Mus musculus/domesticus
Length: 1068  
Fragment?: false
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Allele
Rc3h1<san> | MGI:3581675
 
Name: RING CCCH (C3H) domains 1; sanroque
Allele Type: Chemically induced (ENU)
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Protein Coding Gene
MGI:2444024 | Rinl
Type: protein_coding_gene
Organism: mouse, laboratory
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Allele
Itfg2<Gt(OST215121)Lex> | MGI:4235940
Name: integrin alpha FG-GAP repeat containing 2; gene trap OST215121, Lexicon Genetics
Allele Type: Gene trapped
Attribute String: Null/knockout, Reporter
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Genotype
Genotype
Symbol: Batf/Batf
Background: involves: 129S/Sv * C57BL/6 * FVB/N
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pik3cd/Pik3cd Tg(Cd4-cre)1Cwi/?
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bcl6/Bcl6
Background: involves: 129 * C57BL/6 * FVB/N
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rc3h1/Rc3h1 Rc3h2/Rc3h2 Tg(Cd4-cre)1Cwi/?
Background: involves: C57BL/6N * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tnfsf15/Tnfsf15
Background: D1LacJ.129(B6)-Tnfsf15
Zygosity: hm
Has Mutant Allele: true
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Publication
21844204 | J:177784
First Author: Bertossi A
Year: 2011
Journal: J Exp Med
Title: Loss of Roquin induces early death and immune deregulation but not autoimmunity.
Volume: 208
Issue: 9
Pages: 1749-56
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Publication
30610163 | J:270110
First Author: Lownik JC
Year: 2019
Journal: J Immunol
Title: B Cell ADAM10 Controls Murine Lupus Progression through Regulation of the ICOS:ICOS Ligand Axis.
Volume: 202
Issue: 3
Pages: 664-674
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Publication
20668237 | J:163595
First Author: Teh CE
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: T-cell regulation by casitas B-lineage lymphoma (Cblb) is a critical failsafe against autoimmune disease due to autoimmune regulator (Aire) deficiency.
Volume: 107
Issue: 33
Pages: 14709-14
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Publication
24614103 | J:209612
First Author: Wu J
Year: 2014
Journal: J Clin Invest
Title: iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions.
Volume: 124
Issue: 4
Pages: 1685-98
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Publication
31819031 | J:292424
First Author: Jang E
Year: 2019
Journal: Exp Mol Med
Title: Bach2 deficiency leads autoreactive B cells to produce IgG autoantibodies and induce lupus through a T cell-dependent extrafollicular pathway.
Volume: 51
Issue: 12
Pages: 1-13
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Publication
19478203 | J:164756
First Author: Wigren M
Year: 2009
Journal: Circ Res
Title: Atheroprotective effects of Alum are associated with capture of oxidized LDL antigens and activation of regulatory T cells.
Volume: 104
Issue: 12
Pages: e62-70
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Publication
18768854 | J:139100
First Author: Kamperschroer C
Year: 2008
Journal: J Immunol
Title: SAP enables T cells to help B cells by a mechanism distinct from Th cell programming or CD40 ligand regulation.
Volume: 181
Issue: 6
Pages: 3994-4003
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Publication
15661906 | J:96411
First Author: Krawczyk CM
Year: 2005
Journal: J Immunol
Title: Differential control of CD28-regulated in vivo immunity by the E3 ligase Cbl-b.
Volume: 174
Issue: 3
Pages: 1472-8
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Publication
16754717 | J:124375
First Author: Cannons JL
Year: 2006
Journal: J Exp Med
Title: SAP regulates T cell-mediated help for humoral immunity by a mechanism distinct from cytokine regulation.
Volume: 203
Issue: 6
Pages: 1551-65
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Publication
36078100 | J:336690
 
First Author: Busse M
Year: 2022
Journal: Cells
Title: IL-10 Producing B Cells Protect against LPS-Induced Murine Preterm Birth by Promoting PD1- and ICOS-Expressing T Cells.
Volume: 11
Issue: 17
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Publication
21098093 | J:176869
First Author: Batten M
Year: 2010
Journal: J Exp Med
Title: IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells.
Volume: 207
Issue: 13
Pages: 2895-906
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Publication
27859053 | J:246248
First Author: Jayachandran N
Year: 2017
Journal: Eur J Immunol
Title: B-cell-intrinsic function of TAPP adaptors in controlling germinal center responses and autoantibody production in mice.
Volume: 47
Issue: 2
Pages: 280-290
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Publication
17218615 | J:136611
First Author: Van Hove CL
Year: 2007
Journal: Am J Respir Cell Mol Biol
Title: Prolonged inhaled allergen exposure can induce persistent tolerance.
Volume: 36
Issue: 5
Pages: 573-84
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Publication
15944258 | J:100788
First Author: Thoeni G
Year: 2005
Journal: J Immunol
Title: Tetrahydro-4-aminobiopterin attenuates dendritic cell-induced T cell priming independently from inducible nitric oxide synthase.
Volume: 174
Issue: 12
Pages: 7584-91
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Publication
22908333 | J:190232
First Author: Shalaby KH
Year: 2012
Journal: J Immunol
Title: ICOS-expressing CD4 T cells induced via TLR4 in the nasal mucosa are capable of inhibiting experimental allergic asthma.
Volume: 189
Issue: 6
Pages: 2793-804
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Publication
31152091 | J:289871
 
First Author: Ovcinnikovs V
Year: 2019
Journal: Sci Immunol
Title: CTLA-4-mediated transendocytosis of costimulatory molecules primarily targets migratory dendritic cells.
Volume: 4
Issue: 35
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Publication
22450810 | J:188462
First Author: Good-Jacobson KL
Year: 2012
Journal: J Immunol
Title: CD80 expression on B cells regulates murine T follicular helper development, germinal center B cell survival, and plasma cell generation.
Volume: 188
Issue: 9
Pages: 4217-25
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Publication
20826752 | J:164283
First Author: Rolf J
Year: 2010
Journal: J Immunol
Title: Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction.
Volume: 185
Issue: 7
Pages: 4042-52
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Publication
24378538 | J:208352
First Author: Smigiel KS
Year: 2014
Journal: J Exp Med
Title: CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets.
Volume: 211
Issue: 1
Pages: 121-36
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Publication
22105301 | J:187798
First Author: Ko HJ
Year: 2012
Journal: Eur J Immunol
Title: Expansion of Tfh-like cells during chronic Salmonella exposure mediates the generation of autoimmune hypergammaglobulinemia in MyD88-deficient mice.
Volume: 42
Issue: 3
Pages: 618-28
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Publication
29884702 | J:264075
First Author: Sun IH
Year: 2018
Journal: J Immunol
Title: mTOR Complex 1 Signaling Regulates the Generation and Function of Central and Effector Foxp3+ Regulatory T Cells.
Volume: 201
Issue: 2
Pages: 481-492
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Publication
22891340 | J:188573
First Author: Xie DL
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Tumor suppressor TSC1 is critical for T-cell anergy.
Volume: 109
Issue: 35
Pages: 14152-7
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Publication
15014176 | J:323859
First Author: Kohyama M
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Inducible costimulator-dependent IL-10 production by regulatory T cells specific for self-antigen.
Volume: 101
Issue: 12
Pages: 4192-7
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Publication
28652395 | J:250822
First Author: Gullicksrud JA
Year: 2017
Journal: J Immunol
Title: Differential Requirements for Tcf1 Long Isoforms in CD8+ and CD4+ T Cell Responses to Acute Viral Infection.
Volume: 199
Issue: 3
Pages: 911-919
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Publication
29661826 | J:261476
First Author: Marangoni F
Year: 2018
Journal: J Immunol
Title: Tumor Tolerance-Promoting Function of Regulatory T Cells Is Optimized by CD28, but Strictly Dependent on Calcineurin.
Volume: 200
Issue: 10
Pages: 3647-3661
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Publication
17475832 | J:331613
First Author: Hurchla MA
Year: 2007
Journal: J Immunol
Title: Unexpected role of B and T lymphocyte attenuator in sustaining cell survival during chronic allostimulation.
Volume: 178
Issue: 10
Pages: 6073-82
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Publication
22434910 | J:183484
First Author: Yu M
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Signal inhibition by the dual-specific phosphatase 4 impairs T cell-dependent B-cell responses with age.
Volume: 109
Issue: 15
Pages: E879-88
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Publication
20224552 | J:160381
First Author: Lee AJ
Year: 2010
Journal: EMBO J
Title: Regulation of natural killer T-cell development by deubiquitinase CYLD.
Volume: 29
Issue: 9
Pages: 1600-12
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Publication
34290714 | J:316884
 
First Author: Di Giorgio E
Year: 2021
Journal: Front Immunol
Title: A Biological Circuit Involving Mef2c, Mef2d, and Hdac9 Controls the Immunosuppressive Functions of CD4+Foxp3+ T-Regulatory Cells.
Volume: 12
Pages: 703632
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Publication
31563695 | J:282159
First Author: Chen J
Year: 2019
Journal: Exp Cell Res
Title: Lkb1 in dendritic cells restricts CD8+Foxp3+regulatory T cells expansion in vivo.
Volume: 384
Issue: 2
Pages: 111650
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Publication
37575256 | J:347826
 
First Author: Curtiss ML
Year: 2023
Journal: Front Immunol
Title: Chitinase-3-like 1 regulates T(H)2 cells, T(FH) cells and IgE responses to helminth infection.
Volume: 14
Pages: 1158493
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Publication
17617602 | J:149397
First Author: Nurieva RI
Year: 2007
Journal: J Immunol
Title: A costimulation-initiated signaling pathway regulates NFATc1 transcription in T lymphocytes.
Volume: 179
Issue: 2
Pages: 1096-103
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Publication
19553531 | J:151403
First Author: Kool M
Year: 2009
Journal: J Immunol
Title: An anti-inflammatory role for plasmacytoid dendritic cells in allergic airway inflammation.
Volume: 183
Issue: 2
Pages: 1074-82
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Publication
30258434 | J:295510
 
First Author: Niu L
Year: 2018
Journal: Front Immunol
Title: Akt2 Regulates the Differentiation and Function of NKT17 Cells via FoxO-1-ICOS Axis.
Volume: 9
Pages: 1940
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Publication
26456940 | J:312638
First Author: Runtsch MC
Year: 2015
Journal: Oncotarget
Title: MicroRNA-146a constrains multiple parameters of intestinal immunity and increases susceptibility to DSS colitis.
Volume: 6
Issue: 30
Pages: 28556-72
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Publication
27226091 | J:319200
First Author: Corneth OB
Year: 2016
Journal: J Immunol
Title: Enhanced Expression of Bruton's Tyrosine Kinase in B Cells Drives Systemic Autoimmunity by Disrupting T Cell Homeostasis.
Volume: 197
Issue: 1
Pages: 58-67
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Protein
A0A668KLW6
Organism: Mus musculus/domesticus
Length: 257  
Fragment?: false
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Publication
23451046 | J:199407
First Author: Schaefer JS
Year: 2013
Journal: PLoS One
Title: Small intestine inflammation in Roquin-mutant and Roquin-deficient mice.
Volume: 8
Issue: 2
Pages: e56436
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Publication
23812589 | J:204754
First Author: Zeng H
Year: 2013
Journal: Nature
Title: mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function.
Volume: 499
Issue: 7459
Pages: 485-90
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Publication
27501248 | J:236613
First Author: Im SJ
Year: 2016
Journal: Nature
Title: Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy.
Volume: 537
Issue: 7620
Pages: 417-421
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Publication
34203838 | J:339390
 
First Author: Montes-Casado M
Year: 2021
Journal: Int J Mol Sci
Title: The PI-3-Kinase P110α Catalytic Subunit of T Lymphocytes Modulates Collagen-Induced Arthritis.
Volume: 22
Issue: 12
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Publication
25250764 | J:222505
First Author: Deakin A
Year: 2014
Journal: PLoS One
Title: Characterisation of a K390R ITK kinase dead transgenic mouse--implications for ITK as a therapeutic target.
Volume: 9
Issue: 9
Pages: e107490
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Protein Coding Gene
MGI:1859147 | Batf
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1096342 | Rhoa
Type: protein_coding_gene
Organism: mouse, laboratory
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Allele
Pten<tm2.1Ppp> | MGI:2679886
Name: phosphatase and tensin homolog; targeted mutation 2.1, Pier Paolo Pandolfi
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Scarf1<tm1Tkms> | MGI:5562868
Name: scavenger receptor class F, member 1; targeted mutation 1, Terry K Means
Allele Type: Targeted
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Cd274/Cd274
Background: C.129S-Cd274
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Itfg2/Itfg2
Background: involves: 129S5/SvEvBrd * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Foxp3/Foxp3 Ikzf4/Ikzf4
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctps1/Ctps1 Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: B6.Cg-Ctps1 Gt(ROSA)26Sor
Zygosity: cn
Has Mutant Allele: true
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Protein Coding Gene
MGI:96546 | Il1r2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1343139 | Ikzf4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2449455 | Scarf1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1915450 | Itfg2
Type: protein_coding_gene
Organism: mouse, laboratory
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Allele
Cd274<tm1Lpc> | MGI:3043876
Name: CD274 antigen; targeted mutation 1, Lieping Chen
Allele Type: Targeted
Attribute String: Null/knockout
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