Type |
Details |
Score |
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Siekevitz M |
Year: |
1982 |
Journal: |
Eur J Immunol |
Title: |
The genetic basis of antibody production: the dominant anti-arsonate idiotype response of the strain A mouse. |
Volume: |
12 |
Issue: |
12 |
Pages: |
1023-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sims J |
Year: |
1982 |
Journal: |
Science |
Title: |
Somatic mutation in genes for the variable portion of the immunoglobulin heavy chain. |
Volume: |
216 |
Issue: |
4543 |
Pages: |
309-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barnes N |
Year: |
2002 |
Journal: |
Immunity |
Title: |
FcgammaRI-deficient mice show multiple alterations to inflammatory and immune responses. |
Volume: |
16 |
Issue: |
3 |
Pages: |
379-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zakut R |
Year: |
1980 |
Journal: |
Nucleic Acids Res |
Title: |
Cloning and sequence of the cDNA corresponding to the variable region of immunoglobulin heavy chain MPC11. |
Volume: |
8 |
Issue: |
16 |
Pages: |
3591-601 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
117
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Givol D |
Year: |
1981 |
Journal: |
Nature |
Title: |
Diversity of germ-line immunoglobulin VH genes. |
Volume: |
292 |
Issue: |
5822 |
Pages: |
426-30 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
117
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Sakano H |
Year: |
1980 |
Journal: |
Nature |
Title: |
Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes. |
Volume: |
286 |
Issue: |
5774 |
Pages: |
676-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Auffray C |
Year: |
1981 |
Journal: |
Gene |
Title: |
Mouse immunoglobulin A: nucleotide sequence of the structural gene for the alpha heavy chain derived from cloned cDNAs. |
Volume: |
13 |
Issue: |
4 |
Pages: |
365-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen Q |
Year: |
2000 |
Journal: |
Nature |
Title: |
Development of Th1-type immune responses requires the type I cytokine receptor TCCR. |
Volume: |
407 |
Issue: |
6806 |
Pages: |
916-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rinfret A |
Year: |
1989 |
Journal: |
Mol Immunol |
Title: |
Cloning, sequencing and expression of the rearranged MOPC 315 VH gene segment. |
Volume: |
26 |
Issue: |
4 |
Pages: |
431-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
9
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Thirion S |
Year: |
1996 |
Journal: |
Immunogenetics |
Title: |
PCR cloning and sequencing of a CD3-specific monoclonal antibody. |
Volume: |
43 |
Issue: |
3 |
Pages: |
167-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rocca-Serra J |
Year: |
1983 |
Journal: |
EMBO J |
Title: |
Analysis of antibody diversity: V-D-J mRNA nucleotide sequence of four anti-GAT monoclonal antibodies. A paucigene system using alternate D-J recombinations to generate functionally similar hypervariable regions. |
Volume: |
2 |
Issue: |
6 |
Pages: |
867-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kwak JW |
Year: |
1996 |
Journal: |
Gene |
Title: |
Cloning and characterization of cDNAs coding for heavy and light chains of a monoclonal antibody (MabA34) specific for human plasma apolipoprotein A-I. |
Volume: |
173 |
Issue: |
2 |
Pages: |
257-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Press JL |
Year: |
1991 |
Journal: |
Mol Immunol |
Title: |
A new germline VH36-60 gene is used in the neonatal primary and adult memory response to (T,G)-A--L. |
Volume: |
28 |
Issue: |
11 |
Pages: |
1217-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nishimura H |
Year: |
2006 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Involvement of a tissue-specific autoantibody in skin disorders of murine systemic lupus erythematosus and autoinflammatory diseases. |
Volume: |
103 |
Issue: |
9 |
Pages: |
3292-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lipsanen V |
Year: |
1997 |
Journal: |
Int Immunol |
Title: |
Restricted CDR3 length of the heavy chain is characteristic of six randomly isolated disease-associated VH J558+ IgM autoantibodies in lupus prone motheaten mice. |
Volume: |
9 |
Issue: |
5 |
Pages: |
655-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yoh K |
Year: |
2003 |
Journal: |
J Am Soc Nephrol |
Title: |
Transgenic overexpression of GATA-3 in T lymphocytes improves autoimmune glomerulonephritis in mice with a BXSB/MpJ-Yaa genetic background. |
Volume: |
14 |
Issue: |
10 |
Pages: |
2494-502 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alarcón-Riquelme ME |
Year: |
1995 |
Journal: |
Clin Exp Immunol |
Title: |
CDR3 regions in the preimmune VH B cell repertoire of lpr mice. |
Volume: |
101 |
Issue: |
1 |
Pages: |
73-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Neubert K |
Year: |
2008 |
Journal: |
Nat Med |
Title: |
The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis. |
Volume: |
14 |
Issue: |
7 |
Pages: |
748-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shahinian A |
Year: |
1993 |
Journal: |
Science |
Title: |
Differential T cell costimulatory requirements in CD28-deficient mice. |
Volume: |
261 |
Issue: |
5121 |
Pages: |
609-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Maaser C |
Year: |
2004 |
Journal: |
Infect Immun |
Title: |
Clearance of Citrobacter rodentium requires B cells but not secretory immunoglobulin A (IgA) or IgM antibodies. |
Volume: |
72 |
Issue: |
6 |
Pages: |
3315-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roes J |
Year: |
1993 |
Journal: |
J Exp Med |
Title: |
Immunoglobulin D (IgD)-deficient mice reveal an auxiliary receptor function for IgD in antigen-mediated recruitment of B cells. |
Volume: |
177 |
Issue: |
1 |
Pages: |
45-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Azeredo da Silveira S |
Year: |
2002 |
Journal: |
J Exp Med |
Title: |
Complement activation selectively potentiates the pathogenicity of the IgG2b and IgG3 isotypes of a high affinity anti-erythrocyte autoantibody. |
Volume: |
195 |
Issue: |
6 |
Pages: |
665-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hill L |
Year: |
2023 |
Journal: |
EMBO J |
Title: |
Enhancers of the PAIR4 regulatory module promote distal V(H) gene recombination at the Igh locus. |
Volume: |
42 |
Issue: |
15 |
Pages: |
e112741 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hill L |
Year: |
2020 |
Journal: |
Nature |
Title: |
Wapl repression by Pax5 promotes V gene recombination by Igh loop extrusion. |
Volume: |
584 |
Issue: |
7819 |
Pages: |
142-147 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nimmerjahn F |
Year: |
2010 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
FcγRIV deletion reveals its central role for IgG2a and IgG2b activity in vivo. |
Volume: |
107 |
Issue: |
45 |
Pages: |
19396-401 |
|
•
•
•
•
•
|
Publication |
First Author: |
Haddad D |
Year: |
2011 |
Journal: |
EMBO J |
Title: |
Sense transcription through the S region is essential for immunoglobulin class switch recombination. |
Volume: |
30 |
Issue: |
8 |
Pages: |
1608-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shapiro DA |
Year: |
1998 |
Journal: |
J Immunol |
Title: |
Gamma 3 gene-disrupted mice selectively deficient in the dominant IgG subclass made to bacterial polysaccharides undergo normal isotype switching after immunization with polysaccharide-protein conjugate vaccines. |
Volume: |
161 |
Issue: |
7 |
Pages: |
3393-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
McLay J |
Year: |
2002 |
Journal: |
J Immunol |
Title: |
Gamma 3 gene-disrupted mice selectively deficient in the dominant IgG subclass made to bacterial polysaccharides. II. Increased susceptibility to fatal pneumococcal sepsis due to absence of anti-polysaccharide IgG3 is corrected by induction of anti-polysaccharide IgG1. |
Volume: |
168 |
Issue: |
7 |
Pages: |
3437-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tas JM |
Year: |
2016 |
Journal: |
Science |
Title: |
Visualizing antibody affinity maturation in germinal centers. |
Volume: |
351 |
Issue: |
6277 |
Pages: |
1048-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Helgason CD |
Year: |
2000 |
Journal: |
J Exp Med |
Title: |
A dual role for Src homology 2 domain-containing inositol-5-phosphatase (SHIP) in immunity: aberrant development and enhanced function of b lymphocytes in ship -/- mice. |
Volume: |
191 |
Issue: |
5 |
Pages: |
781-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liljedahl M |
Year: |
1998 |
Journal: |
Immunity |
Title: |
Altered antigen presentation in mice lacking H2-O. |
Volume: |
8 |
Issue: |
2 |
Pages: |
233-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gavin AL |
Year: |
1998 |
Journal: |
J Immunol |
Title: |
Identification of the mouse IgG3 receptor: implications for antibody effector function at the interface between innate and adaptive immunity. |
Volume: |
160 |
Issue: |
1 |
Pages: |
20-3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lapter S |
Year: |
2007 |
Journal: |
Stem Cells |
Title: |
Structure and implied functions of truncated B-cell receptor mRNAs in early embryo and adult mesenchymal stem cells: Cdelta replaces Cmu in mu heavy chain-deficient mice. |
Volume: |
25 |
Issue: |
3 |
Pages: |
761-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Castigli E |
Year: |
2004 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Impaired IgA class switching in APRIL-deficient mice. |
Volume: |
101 |
Issue: |
11 |
Pages: |
3903-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Egawa T |
Year: |
2003 |
Journal: |
Curr Biol |
Title: |
Requirement for CARMA1 in antigen receptor-induced NF-kappa B activation and lymphocyte proliferation. |
Volume: |
13 |
Issue: |
14 |
Pages: |
1252-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Samara M |
Year: |
2006 |
Journal: |
Int Immunol |
Title: |
Germ line transcription in mice bearing neor gene downstream of Igamma3 exon in the Ig heavy chain locus. |
Volume: |
18 |
Issue: |
4 |
Pages: |
581-9 |
|
•
•
•
•
•
|
Allele |
Name: |
immunoglobulin heavy chain 8 (heavy chain of IgG3); targeted mutation 2, Ahmed Amine Khamlichi |
Allele Type: |
Targeted |
|
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant stock, targeted mutation |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Igh-8/Igh-8 |
Background: |
involves: 129S2/SvPas |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Diaw L |
Year: |
1999 |
Journal: |
J Exp Med |
Title: |
Restricted immunoglobulin variable region (Ig V) gene expression accompanies secondary rearrangements of light chain Ig V genes in mouse plasmacytomas. |
Volume: |
190 |
Issue: |
10 |
Pages: |
1405-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Monestier M |
Year: |
2000 |
Journal: |
J Biol Chem |
Title: |
Molecular and structural properties of three autoimmune IgG monoclonal antibodies to histone H2B. |
Volume: |
275 |
Issue: |
18 |
Pages: |
13558-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adams JM |
Year: |
1980 |
Journal: |
Biochemistry |
Title: |
Molecular cloning of mouse immunoglobulin heavy chain messenger ribonucleic acids coding for mu, alpha, gamma 1, gamma 2a, and gamma 3 chains. |
Volume: |
19 |
Issue: |
12 |
Pages: |
2711-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marcu KB |
Year: |
1980 |
Journal: |
Cell |
Title: |
5' flanking region of immunoglobulin heavy chain constant region genes displays length heterogeneity in germlines of inbred mouse strains. |
Volume: |
22 |
Issue: |
1 Pt 1 |
Pages: |
187-96 |
|
•
•
•
•
•
|