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Search results 501 to 600 out of 903 for Il13

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Type Details Score
Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:165964
     
First Author: Mammalian Functional Genomics Centre
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba
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Publication
- | J:15839
       
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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MP Term
MP:0008671 | abnormal interleukin-13 secretion
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MP Term
MP:0008672 | increased interleukin-13 secretion
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MP Term
MP:0008608 | increased circulating interleukin-13 level
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MP Term
MP:0008607 | abnormal circulating interleukin-13 level
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Publication
23851685 | J:205695
First Author: Furusawa J
Year: 2013
Journal: J Immunol
Title: Critical role of p38 and GATA3 in natural helper cell function.
Volume: 191
Issue: 4
Pages: 1818-26
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Publication
33188077 | J:300741
First Author: Kamran M
Year: 2020
Journal: J Immunol
Title: The Clusters of Transcription Factors NFATC2, STAT5, GATA2, AP1, RUNX1 and EGR2 Binding Sites at the Induced Il13 Enhancers Mediate Il13 Gene Transcription in Response to Antigenic Stimulation.
Volume: 205
Issue: 12
Pages: 3311-3318
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Regulatory Region
MGI:4880761 | Rr9
Type: TF_binding_site
Organism: mouse, laboratory
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MP Term
MP:0008609 | decreased circulating interleukin-13 level
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MP Term
MP:0008673 | decreased interleukin-13 secretion
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Publication
21131966 | J:167446
First Author: Tanaka S
Year: 2011
Journal: Nat Immunol
Title: The enhancer HS2 critically regulates GATA-3-mediated Il4 transcription in T(H)2 cells.
Volume: 12
Issue: 1
Pages: 77-85
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Publication
22365664 | J:181626
First Author: Harada Y
Year: 2012
Journal: Immunity
Title: The 3' enhancer CNS2 is a critical regulator of interleukin-4-mediated humoral immunity in follicular helper T cells.
Volume: 36
Issue: 2
Pages: 188-200
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Allele
Il13<em2(IL13)Smoc> | MGI:7290425
Name: interleukin 13; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Il13<em3Smoc> | MGI:7290426
Name: interleukin 13; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Tg(CD4-Il13)431Anjm | MGI:6459873
Name: transegne insertion 431, Andrew NJ McKenzie
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:6428914 | C57BL/6JSmoc-Il13<em2(IL13)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6354890 | C57BL/6JSmoc-Il13<em3Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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CL Term
CL:0002679 | natural helper lymphocyte
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Allele
Rr250409<em1Kejz> | MGI:7709976
Name: regulatory region 250409; endonuclease-mediated mutation 1, Keji Zhao
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Il5<tm1Anjm> | MGI:3688245
Name: interleukin 5; targeted mutation 1, Andrew NJ McKenzie
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Rr9<tm1.1Kubo> | MGI:4880765
Name: regulatory region 9; targeted mutation 1.1, Masato Kubo
Allele Type: Targeted
Attribute String: Modified regulatory region, Null/knockout
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Publication
9670052 | J:112473
First Author: Emson CL
Year: 1998
Journal: J Exp Med
Title: Interleukin (IL)-4-independent induction of immunoglobulin (Ig)E, and perturbation of T cell development in transgenic mice expressing IL-13.
Volume: 188
Issue: 2
Pages: 399-404
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Allele
Il4/Il13<tm3Anjm> | MGI:3038244
Name: interleukin 4; targeted mutation 3, Andrew NJ McKenzie
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Il4/Il13<tm3Anjm> | MGI:3038245
Name: interleukin 13; targeted mutation 3, Andrew NJ McKenzie
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Tg(tetO-Il13)1Mer | MGI:3605464
Name: transgene insertion 1, Marc E Rothenberg
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
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Allele
Il5<tm2Anjm> | MGI:3689812
Name: interleukin 5; targeted mutation 2, Andrew NJ McKenzie
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Rr250409<tm1Lky> | MGI:3760155
Name: regulatory region 250409; targeted mutation 1, Richard M Locksley
Allele Type: Targeted
Attribute String: Modified regulatory region, Null/knockout
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Allele
Tg(Scgb1a1-Il13)2Eli | MGI:3832264
Name: transgene insertion 2, Jack A Elias
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:7715202 | B6(Cg)-Rr9<tm1.1Kubo>/Kubo
Attribute String: mutant strain, targeted mutation
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Strain
MGI:4881481 | C57BL/6-Rr9<tm1.1Kubo>
Attribute String: coisogenic, mutant strain, targeted mutation
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Allele
Tg(Il13-DsRed)K1Wep | MGI:6118070
Name: transgene insertion K1, William E Paul
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Il13<em1(icre)Smoc> | MGI:7290424
Name: interleukin 13; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Recombinase
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Strain
MGI:7781353 | C57BL/6JSmoc-Tnfrsf4<em1(TNFRSF4)Smoc> Il13<em2(IL13)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Genotype
Genotype
Symbol: Il5/Il5
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rr9/Rr9
Background: C57BL/6-Rr9
Zygosity: hm
Has Mutant Allele: true
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Protein Domain
IPR018799 | TRAF3IP1
Type: Family
Description: TRAF3-interacting protein 1 (TRAF3IP1) recruits TRAF3 (tumour necrosis factor receptor-associated factor 3) and DISC1 (Disrupted-In-Schizophrenia 1) to the microtubules and is conserved from worms to humans []. The N-terminal region is the microtubule binding domain and is well-conserved; the C-terminal 100 residues, also well-conserved, constitute the coiled-coil region which binds to TRAF3. The central region of the protein is rich in lysine and glutamic acid and carries KKE motifs which may also be necessary for tubulin-binding, but this region is the least well-conserved []. In humans, it plays an inhibitory role on IL13 signaling by binding to IL13RA1. It is involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding [, ].
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Publication
22826322 | J:189872
First Author: Lee CG
Year: 2012
Journal: J Immunol
Title: Chitinase 1 is a biomarker for and therapeutic target in scleroderma-associated interstitial lung disease that augments TGF-β1 signaling.
Volume: 189
Issue: 5
Pages: 2635-44
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Protein
Q149C2
Organism: Mus musculus/domesticus
Length: 625  
Fragment?: false
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Protein
A0A087WQD8
Organism: Mus musculus/domesticus
Length: 654  
Fragment?: false
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Publication
10791955 | -
First Author: Ling L
Year: 2000
Journal: J Biol Chem
Title: MIP-T3, a novel protein linking tumor necrosis factor receptor-associated factor 3 to the microtubule network.
Volume: 275
Issue: 31
Pages: 23852-60
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Publication
12812986 | -
First Author: Morris JA
Year: 2003
Journal: Hum Mol Genet
Title: DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation.
Volume: 12
Issue: 13
Pages: 1591-608
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Publication
12935900 | -
First Author: Niu Y
Year: 2003
Journal: FEBS Lett
Title: MIP-T3 associates with IL-13Ralpha1 and suppresses STAT6 activation in response to IL-13 stimulation.
Volume: 550
Issue: 1-3
Pages: 139-43
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Protein Domain
IPR042576 | TRAF3IP1_N_sf
Type: Homologous_superfamily
Description: TRAF3-interacting protein 1 (TRAF3IP1) recruits TRAF3 (tumour necrosis factor receptor-associated factor 3) and DISC1 (Disrupted-In-Schizophrenia 1) to the microtubules and is conserved from worms to humans []. The N-terminal region is the microtubule binding domain and is well-conserved; the C-terminal 100 residues, also well-conserved, constitute the coiled-coil region which binds to TRAF3. The central region of the protein is rich in lysine and glutamic acid and carries KKE motifs which may also be necessary for tubulin-binding, but this region is the least well-conserved []. In humans, it plays an inhibitory role on IL13 signaling by binding to IL13RA1. It is involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding [, ].This superfamily represents the N-terminal domain of TRAF3-interacting protein 1.
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Protein Domain
IPR040468 | TRAF3IP1_N
Type: Domain
Description: TRAF3-interacting protein 1 (TRAF3IP1) recruits TRAF3 (tumour necrosis factor receptor-associated factor 3) and DISC1 (Disrupted-In-Schizophrenia 1) to the microtubules and is conserved from worms to humans []. The N-terminal region is the microtubule binding domain and is well-conserved; the C-terminal 100 residues, also well-conserved, constitute the coiled-coil region which binds to TRAF3. The central region of the protein is rich in lysine and glutamic acid and carries KKE motifs which may also be necessary for tubulin-binding, but this region is the least well-conserved []. In humans, it plays an inhibitory role on IL13 signaling by binding to IL13RA1. It is involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding [, ].This entry represents the N-terminal domain of TRAF3-interacting protein 1.
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Strain
MGI:5816110 | C.129X(Cg)-Rr250409<tm1Lky>/RadkJ
Attribute String: congenic, mutant strain, targeted mutation
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Publication
19494294 | J:149293
First Author: Aoki K
Year: 2009
Journal: J Immunol
Title: Regulation of DNA demethylation during maturation of CD4+ naive T cells by the conserved noncoding sequence 1.
Volume: 182
Issue: 12
Pages: 7698-707
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Publication
12060560 | J:132802
First Author: Homer RJ
Year: 2002
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Pulmonary type II cell hypertrophy and pulmonary lipoproteinosis are features of chronic IL-13 exposure.
Volume: 283
Issue: 1
Pages: L52-9
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Publication
35697721 | J:341502
First Author: Kim RL
Year: 2022
Journal: Sci Rep
Title: Mesenchymal stem cells exert their anti-asthmatic effects through macrophage modulation in a murine chronic asthma model.
Volume: 12
Issue: 1
Pages: 9811
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Allele
Il4/Il13<tm1.1Lky> | MGI:4431367
Name: interleukin 4; targeted mutation 1.1, Richard M Locksley
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Il4/Il13<tm1.1Lky> | MGI:4431368
Name: interleukin 13; targeted mutation 1.1, Richard M Locksley
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Il13<tm1(YFP/cre)Lky> | MGI:4459318
Name: interleukin 13; targeted mutation 1, Richard M Locksley
Allele Type: Targeted
Attribute String: No functional change, Recombinase, Reporter
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Allele
Tg(Il4-AmCyan,Il13-DsRed*)1Wep | MGI:6118069
Name: transgene insertion 1, William E Paul
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:6118145 | C57BL/6J-Tg(Il13-DsRed)K1Wep/J
Attribute String: transgenic, mutant strain, coisogenic
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Strain
MGI:6428913 | C57BL/6JSmoc-Il13<em1(icre)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Genotype
Genotype
Symbol: Il4/Il13/Il4/Il13
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Il4/Il13/Il4/Il13
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Il4/Il13/Il4/Il13
Background: C.Cg-Il4/Il13
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Il4/Il13/Il4/Il13
Background: C.Cg-Il4/Il13
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rr250409/Rr250409<+>
Background: involves: 129X1/SvJ * BALB/c * C57BL/6 * FVB
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rr250409/Rr250409
Background: involves: 129X1/SvJ * BALB/c * C57BL/6 * FVB
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Scgb1a1-Il13)2Eli/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Il4/Il13/Il4/Il13
Background: C.129P2/OlaHsd-Il4/Il13
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Il4/Il13/Il4/Il13
Background: C.129P2/OlaHsd-Il4/Il13
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Il4/Il13/Il4/Il13
Background: involves: 129P2/OlaHsd * BALB/c
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Il4/Il13/Il4/Il13
Background: involves: 129P2/OlaHsd * BALB/c
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rr250409/Rr250409
Background: involves: 129X1/SvJ * BALB/c
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Il4/Il13/Il13<+>
Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Il4/Il13/Il4<+>
Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor
Zygosity: ht
Has Mutant Allele: true
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Strain
MGI:4461296 | C.Cg-Il13<tm1(YFP/cre)Lky>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5298397 | C.129S4(B6)-Il13<tm1(YFP/cre)Lky>/J
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:6118142 | C57BL/6J-Tg(Il4-AmCyan,Il13-DsRed*)1Wep/J
Attribute String: coisogenic, mutant strain, transgenic
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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