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Search results 501 to 600 out of 646 for Irf8

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Type Details Score
Publication
27705792 | J:240662
First Author: Seillet C
Year: 2016
Journal: Cell Rep
Title: Deciphering the Innate Lymphoid Cell Transcriptional Program.
Volume: 17
Issue: 2
Pages: 436-447
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Publication
27941786 | J:260180
First Author: Herzig Y
Year: 2017
Journal: Nat Immunol
Title: Transcriptional programs that control expression of the autoimmune regulator gene Aire.
Volume: 18
Issue: 2
Pages: 161-172
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Publication
27135602 | J:260124
First Author: Goldmann T
Year: 2016
Journal: Nat Immunol
Title: Origin, fate and dynamics of macrophages at central nervous system interfaces.
Volume: 17
Issue: 7
Pages: 797-805
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Publication
20008528 | J:155668
First Author: Ginhoux F
Year: 2009
Journal: J Exp Med
Title: The origin and development of nonlymphoid tissue CD103+ DCs.
Volume: 206
Issue: 13
Pages: 3115-30
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Publication
36045707 | J:338451
 
First Author: Shintani A
Year: 2022
Journal: Curr Res Immunol
Title: Dach1 transcription factor regulates the expression of peripheral node addressin and lymphocyte trafficking in lymph nodes.
Volume: 3
Pages: 175-185
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Publication
33979578 | J:314462
First Author: de Mingo Pulido Á
Year: 2021
Journal: Immunity
Title: The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake.
Volume: 54
Issue: 6
Pages: 1154-1167.e7
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Publication
23467089 | J:241283
First Author: Yosef N
Year: 2013
Journal: Nature
Title: Dynamic regulatory network controlling TH17 cell differentiation.
Volume: 496
Issue: 7446
Pages: 461-8
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Publication
35444279 | J:330253
First Author: Chou C
Year: 2022
Journal: Nature
Title: Programme of self-reactive innate-like T cell-mediated cancer immunity.
Volume: 605
Issue: 7908
Pages: 139-145
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Publication
32269339 | J:293313
First Author: Maier B
Year: 2020
Journal: Nature
Title: A conserved dendritic-cell regulatory program limits antitumour immunity.
Volume: 580
Issue: 7802
Pages: 257-262
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Publication
28468974 | J:247750
First Author: Zhu Q
Year: 2017
Journal: J Immunol
Title: Cutting Edge: Distinct Regulatory Mechanisms Control Proinflammatory Cytokines IL-18 and IL-1β.
Volume: 198
Issue: 11
Pages: 4210-4215
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Publication
32341550 | J:291234
First Author: Dawson CA
Year: 2020
Journal: Nat Cell Biol
Title: Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling.
Volume: 22
Issue: 5
Pages: 546-558
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Publication
12935356 | J:86521
First Author: Hoebe K
Year: 2003
Journal: J Endotoxin Res
Title: Lps2: a new locus required for responses to lipopolysaccharide, revealed by germline mutagenesis and phenotypic screening.
Volume: 9
Issue: 4
Pages: 250-5
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Publication
19734904 | J:152783
First Author: Mandal M
Year: 2009
Journal: Nat Immunol
Title: Ras orchestrates exit from the cell cycle and light-chain recombination during early B cell development.
Volume: 10
Issue: 10
Pages: 1110-7
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Publication
21045126 | J:166600
First Author: Blasius AL
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells.
Volume: 107
Issue: 46
Pages: 19973-8
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Publication
27716507 | J:236522
First Author: Chudnovskiy A
Year: 2016
Journal: Cell
Title: Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.
Volume: 167
Issue: 2
Pages: 444-456.e14
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Publication
16897342 | J:111669
First Author: Sollars VE
Year: 2006
Journal: Mamm Genome
Title: Analysis of expansion of myeloid progenitors in mice to identify leukemic susceptibility genes.
Volume: 17
Issue: 8
Pages: 808-21
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Publication
7558020 | J:25567
First Author: Kozak CA
Year: 1995
Journal: Genomics
Title: Genomic cloning of mouse MIF (macrophage inhibitory factor) and genetic mapping of the human and mouse expressed gene and nine mouse pseudogenes.
Volume: 27
Issue: 3
Pages: 405-11
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Publication
33238123 | J:300359
First Author: Zhang H
Year: 2020
Journal: Cell Rep
Title: An IL-27-Driven Transcriptional Network Identifies Regulators of IL-10 Expression across T Helper Cell Subsets.
Volume: 33
Issue: 8
Pages: 108433
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Publication
22366192 | J:184926
First Author: Blackburn J
Year: 2012
Journal: Dev Biol
Title: The role of Irf6 in tooth epithelial invagination.
Volume: 365
Issue: 1
Pages: 61-70
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Publication
35444273 | J:330324
First Author: Masuda T
Year: 2022
Journal: Nature
Title: Specification of CNS macrophage subsets occurs postnatally in defined niches.
Volume: 604
Issue: 7907
Pages: 740-748
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Publication
38164795 | J:344217
First Author: Roy TA
Year: 2024
Journal: Genes Brain Behav
Title: Discovery and validation of genes driving drug-intake and related behavioral traits in mice.
Volume: 23
Issue: 1
Pages: e12875
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Publication
38346162 | J:346895
   
First Author: Guo P
Year: 2024
Journal: Elife
Title: A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis.
Volume: 13
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Publication
26147683 | J:239648
First Author: Bettigole SE
Year: 2015
Journal: Nat Immunol
Title: The transcription factor XBP1 is selectively required for eosinophil differentiation.
Volume: 16
Issue: 8
Pages: 829-37
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Publication
8672127 | J:34474
First Author: Lyu MS
Year: 1996
Journal: Mamm Genome
Title: Genetic mapping of the human and mouse phospholipase C genes.
Volume: 7
Issue: 7
Pages: 501-4
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Publication
10501973 | J:62456
First Author: Lyu MS
Year: 1999
Journal: Mamm Genome
Title: Genetic mapping of six mouse peroxiredoxin genes and fourteen peroxiredoxin related sequences.
Volume: 10
Issue: 10
Pages: 1017-9
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Publication
35315772 | J:322321
   
First Author: Catela C
Year: 2022
Journal: Elife
Title: Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity.
Volume: 11
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Publication
10441734 | J:56825
First Author: Kozak CA
Year: 1999
Journal: Mamm Genome
Title: Identification and genetic mapping of differentially expressed genes in mice differing at the If1 interferon regulatory locus.
Volume: 10
Issue: 9
Pages: 853-7
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Publication
28700664 | J:246066
First Author: Sundberg JP
Year: 2017
Journal: PLoS One
Title: Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
Volume: 12
Issue: 7
Pages: e0180682
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
20932939 | J:168654
First Author: Chung YC
Year: 2011
Journal: Gene Expr Patterns
Title: Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.
Volume: 11
Issue: 1-2
Pages: 84-92
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Publication
24154525 | J:205051
First Author: Miller JA
Year: 2013
Journal: Development
Title: Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.
Volume: 140
Issue: 22
Pages: 4633-44
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Publication
20412781 | J:140465
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Rr174<em1Kmm> | MGI:6368524
Name: regulatory region 174; endonuclease-mediated mutation 1, Kenneth Murphy
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Publication
37645844 | J:361271
     
First Author: Saeki K
Year: 2024
Journal: bioRxiv
Title: IRF8 configures enhancer landscape in postnatal microglia and directs microglia specific transcriptional programs.
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Publication
34968772 | J:319778
 
First Author: Chauhan KS
Year: 2022
Journal: Cell Immunol
Title: IRF8 and BATF3 interaction enhances the cDC1 specific Pfkfb3 gene expression.
Volume: 371
Pages: 104468
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DO Term
DOID:0111985 | immunodeficiency 32B
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Regulatory Region
MGI:6863877 | Rr172
Type: enhancer
Organism: mouse, laboratory
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Regulatory Region
MGI:6863878 | Rr173
Type: enhancer
Organism: mouse, laboratory
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Regulatory Region
MGI:6863879 | Rr174
Type: enhancer
Organism: mouse, laboratory
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Publication
32341037 | J:348808
First Author: Wu H
Year: 2020
Journal: Cancer Res
Title: Loss of a Negative Feedback Loop between IRF8 and AR Promotes Prostate Cancer Growth and Enzalutamide Resistance.
Volume: 80
Issue: 13
Pages: 2927-2939
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Publication
34362833 | J:331194
First Author: Patel A
Year: 2021
Journal: J Immunol
Title: Multimodal Intralesional Therapy for Reshaping the Myeloid Compartment of Tumors Resistant to Anti-PD-L1 Therapy via IRF8 Expression.
Volume: 207
Issue: 5
Pages: 1298-1309
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DO Term
DOID:0111986 | immunodeficiency 32A
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GXD Expression
GXD Expression
 
Probe: MGI:7380580
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3660822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7382870
Age: embryonic day 14.5
Note: Choroid plexus macrophages were not affected in the Irf8 mutant background.
Specimen Label: 3f Choroid plexus Irf8<-/->;Cx3cr1
Detected: true
Specimen Num: 23
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GXD Expression
GXD Expression
 
Probe: MGI:5620494
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3660822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7382874
Age: embryonic day 14.5
Note: Choroid plexus macrophages were not affected in the Irf8 mutant background.
Specimen Label: 3f Choroid plexus Irf8<-/->;Cx3cr1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:7380580
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3660922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7382870
Age: embryonic day 14.5
Note: Choroid plexus macrophages were not affected in the Irf8 mutant background.
Specimen Label: 3f Choroid plexus Irf8<-/->;Cx3cr1
Detected: true
Specimen Num: 23
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GXD Expression
GXD Expression
 
Probe: MGI:5620494
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3660922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7382874
Age: embryonic day 14.5
Note: Choroid plexus macrophages were not affected in the Irf8 mutant background.
Specimen Label: 3f Choroid plexus Irf8<-/->;Cx3cr1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:7380580
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7382870
Age: embryonic day 14.5
Note: There was a reduction in the number of meningeal macrophages noted in the Irf8 mutant background.
Specimen Label: 3f Meninges Irf8<-/->;Cx3cr1
Detected: true
Specimen Num: 22
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GXD Expression
GXD Expression
 
Probe: MGI:5620494
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7382874
Age: embryonic day 14.5
Note: There was a reduction in the number of meningeal macrophages noted in the Irf8 mutant background.
Specimen Label: 3f Meninges Irf8<-/->;Cx3cr1
Detected: true
Specimen Num: 3
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Allele
Irf8<em1Smoc> | MGI:7290582
Name: interferon regulatory factor 8; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6354947 | C57BL/6JSmoc-Irf8<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Gm39266<em3Kmm> | MGI:7767853
Name: predicted gene, 39266; endonuclease-mediated mutation 3, Kenneth M Murphy
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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HT Experiment
GSE128854 | A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment. [scRNA-Seq]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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MP Term
MP:0013651 | increased CD11b-low dendritic cell number
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MP Term
MP:0013652 | decreased CD11b-low dendritic cell number
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MP Term
MP:0013650 | abnormal CD11b-low dendritic cell number
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HT Experiment
GSE231405 | Single-cell transcriptome profiles of wild-type and IRF8KO microglia [scRNA-seq]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Irf8<m2Btlr> | MGI:6305310
Name: interferon regulatory factor 8; mutation 2, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6305314 | C57BL/6J-Irf8<m2Btlr>
Attribute String: mutant strain, coisogenic, chemically induced mutation
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Strain
MGI:6368519 | C57BL/6-Rr172<em1Kmm>/J
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6368523 | C57BL/6-Rr173<em1Kmm>/J
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Irf8/Irf8
Background: C57BL/6J-Irf8
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:7448525 | C57BL/6J-Rr253<em6Kmm> Rr172<em1Kmm>
Attribute String: endonuclease-mediated mutation, mutant strain, coisogenic
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