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Search results 501 to 600 out of 3295 for Kras

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Type Details Score
Publication
35815941 | J:326849
   
First Author: Kerk SA
Year: 2022
Journal: Elife
Title: Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context.
Volume: 11
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Publication
33864001 | J:305481
First Author: Azizi N
Year: 2021
Journal: Oncogene
Title: Loss of activating transcription factor 3 prevents KRAS-mediated pancreatic cancer.
Volume: 40
Issue: 17
Pages: 3118-3135
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Publication
25628462 | J:260326
First Author: Bowman BM
Year: 2015
Journal: Sci Signal
Title: Phosphorylation of FADD by the kinase CK1α promotes KRASG12D-induced lung cancer.
Volume: 8
Issue: 361
Pages: ra9
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Publication
26404002 | J:226774
First Author: Loncle C
Year: 2015
Journal: Cancer Res
Title: IL17 Functions through the Novel REG3β-JAK2-STAT3 Inflammatory Pathway to Promote the Transition from Chronic Pancreatitis to Pancreatic Cancer.
Volume: 75
Issue: 22
Pages: 4852-62
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Publication
25042889 | J:214846
First Author: Yamaguchi T
Year: 2014
Journal: J Pathol
Title: A genetically engineered mouse model developing rapid progressive pancreatic ductal adenocarcinoma.
Volume: 234
Issue: 2
Pages: 228-38
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Publication
32580961 | J:296304
First Author: Wang F
Year: 2020
Journal: Cancer Res
Title: p38γ MAPK Is Essential for Aerobic Glycolysis and Pancreatic Tumorigenesis.
Volume: 80
Issue: 16
Pages: 3251-3264
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Publication
21896780 | J:178325
First Author: Ahn YH
Year: 2011
Journal: Mol Cell Biol
Title: Map2k4 functions as a tumor suppressor in lung adenocarcinoma and inhibits tumor cell invasion by decreasing peroxisome proliferator-activated receptor γ2 expression.
Volume: 31
Issue: 21
Pages: 4270-85
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Publication
24632531 | J:210824
First Author: Byun AJ
Year: 2014
Journal: Cancer Lett
Title: Colon-specific tumorigenesis in mice driven by Cre-mediated inactivation of Apc and activation of mutant Kras.
Volume: 347
Issue: 2
Pages: 191-5
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Publication
31527715 | J:306834
First Author: Parameswaran N
Year: 2019
Journal: Sci Rep
Title: A FAM83A Positive Feed-back Loop Drives Survival and Tumorigenicity of Pancreatic Ductal Adenocarcinomas.
Volume: 9
Issue: 1
Pages: 13396
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Publication
28539837 | J:265014
First Author: Wang Y
Year: 2017
Journal: Int J Biol Sci
Title: Ezh2 Acts as a Tumor Suppressor in Kras-driven Lung Adenocarcinoma.
Volume: 13
Issue: 5
Pages: 652-659
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Publication
25261994 | J:227828
First Author: Mayers JR
Year: 2014
Journal: Nat Med
Title: Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development.
Volume: 20
Issue: 10
Pages: 1193-1198
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Publication
30089720 | J:286945
 
First Author: Bauer AK
Year: 2018
Journal: JCI Insight
Title: Requirement for MUC5AC in KRAS-dependent lung carcinogenesis.
Volume: 3
Issue: 15
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Publication
31310834 | J:294440
First Author: Shi C
Year: 2019
Journal: Cell Mol Gastroenterol Hepatol
Title: Differential Cell Susceptibilities to KrasG12D in the Setting of Obstructive Chronic Pancreatitis.
Volume: 8
Issue: 4
Pages: 579-594
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Publication
21107427 | J:166973
First Author: Junttila MR
Year: 2010
Journal: Nature
Title: Selective activation of p53-mediated tumour suppression in high-grade tumours.
Volume: 468
Issue: 7323
Pages: 567-71
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Publication
34301865 | J:308301
 
First Author: Salmón M
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: KRAS4A induces metastatic lung adenocarcinomas in vivo in the absence of the KRAS4B isoform.
Volume: 118
Issue: 30
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Publication
26683769 | J:237649
First Author: Liao J
Year: 2016
Journal: Cancer Lett
Title: Inhibition of mutant KrasG12D-initiated murine pancreatic carcinoma growth by a dual c-Raf and soluble epoxide hydrolase inhibitor t-CUPM.
Volume: 371
Issue: 2
Pages: 187-93
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Publication
31410985 | J:295866
First Author: Zhang M
Year: 2019
Journal: J Cell Mol Med
Title: Deregulated lncRNA expression profile in the mouse lung adenocarcinomas with KRAS-G12D mutation and P53 knockout.
Volume: 23
Issue: 10
Pages: 6978-6988
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Publication
25748236 | J:311968
First Author: Albury TM
Year: 2015
Journal: Neoplasia
Title: Constitutively active Akt1 cooperates with KRas(G12D) to accelerate in vivo pancreatic tumor onset and progression.
Volume: 17
Issue: 2
Pages: 175-82
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Publication
22665051 | J:197233
First Author: Shi G
Year: 2013
Journal: Oncogene
Title: Maintenance of acinar cell organization is critical to preventing Kras-induced acinar-ductal metaplasia.
Volume: 32
Issue: 15
Pages: 1950-8
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Publication
31545922 | J:305869
First Author: Dong TS
Year: 2019
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Metformin alters the duodenal microbiome and decreases the incidence of pancreatic ductal adenocarcinoma promoted by diet-induced obesity.
Volume: 317
Issue: 6
Pages: G763-G772
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Publication
34735515 | J:312867
First Author: Walcheck MT
Year: 2021
Journal: PLoS One
Title: Sex-dependent development of Kras-induced anal squamous cell carcinoma in mice.
Volume: 16
Issue: 11
Pages: e0259245
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Publication
26146959 | J:226338
First Author: Zou M
Year: 2015
Journal: Lab Invest
Title: KRAS(G12D)-mediated oncogenic transformation of thyroid follicular cells requires long-term TSH stimulation and is regulated by SPRY1.
Volume: 95
Issue: 11
Pages: 1269-77
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Publication
39342278 | J:357744
First Author: Sozzi S
Year: 2024
Journal: J Exp Clin Cancer Res
Title: Inactivation of HIPK2 attenuates KRAS(G12D) activity and prevents pancreatic tumorigenesis.
Volume: 43
Issue: 1
Pages: 265
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Publication
31330317 | J:293294
First Author: Gao C
Year: 2019
Journal: Cell Mol Gastroenterol Hepatol
Title: PYK2 Is Involved in Premalignant Acinar Cell Reprogramming and Pancreatic Ductal Adenocarcinoma Maintenance by Phosphorylating β-CateninY654.
Volume: 8
Issue: 4
Pages: 561-578
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Publication
37760426 | J:341359
 
First Author: Kalailingam P
Year: 2023
Journal: Cancers (Basel)
Title: Conditional Knockout of N-WASP Enhanced the Formation of Keratinizing Squamous Cell Carcinoma Induced by KRas(G12D).
Volume: 15
Issue: 18
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Publication
27941872 | J:243050
First Author: Dumartin L
Year: 2017
Journal: Oncogene
Title: ER stress protein AGR2 precedes and is involved in the regulation of pancreatic cancer initiation.
Volume: 36
Issue: 22
Pages: 3094-3103
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Publication
39128004 | J:353582
First Author: Huber A
Year: 2024
Journal: Cell Rep
Title: Mutant TP53 switches therapeutic vulnerability during gastric cancer progression within interleukin-6 family cytokines.
Volume: 43
Issue: 8
Pages: 114616
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Publication
30042178 | J:266580
 
First Author: Kobayashi T
Year: 2018
Journal: Development
Title: Lin28a overexpression reveals the role of Erk signaling in articular cartilage development.
Volume: 145
Issue: 15
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Publication
36995340 | J:341372
 
First Author: Gonzalez MA
Year: 2023
Journal: J Exp Med
Title: Phagocytosis increases an oxidative metabolic and immune suppressive signature in tumor macrophages.
Volume: 220
Issue: 6
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Publication
23436574 | J:196071
First Author: van der Weyden L
Year: 2013
Journal: J Pathol
Title: Cancer of mice and men: old twists and new tails.
Volume: 230
Issue: 1
Pages: 4-16
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Publication
30456390 | J:287931
First Author: Pitarresi JR
Year: 2018
Journal: Life Sci Alliance
Title: Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth.
Volume: 1
Issue: 5
Pages: e201800190
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Publication
19421407 | J:148887
First Author: Efeyan A
Year: 2009
Journal: PLoS One
Title: Limited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression.
Volume: 4
Issue: 5
Pages: e5475
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Publication
20609353 | J:161780
First Author: Puyol M
Year: 2010
Journal: Cancer Cell
Title: A synthetic lethal interaction between K-Ras oncogenes and Cdk4 unveils a therapeutic strategy for non-small cell lung carcinoma.
Volume: 18
Issue: 1
Pages: 63-73
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Publication
25127677 | J:314626
First Author: Hermann PC
Year: 2014
Journal: Gastroenterology
Title: Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.
Volume: 147
Issue: 5
Pages: 1119-33.e4
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Publication
23523371 | J:198227
First Author: Snyder EL
Year: 2013
Journal: Mol Cell
Title: Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma.
Volume: 50
Issue: 2
Pages: 185-99
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Publication
27633013 | J:235647
First Author: Liu X
Year: 2016
Journal: Genes Dev
Title: Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia.
Volume: 30
Issue: 17
Pages: 1943-55
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Publication
35835117 | J:327356
First Author: Orstad G
Year: 2022
Journal: Dev Cell
Title: FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma.
Volume: 57
Issue: 15
Pages: 1866-1882.e10
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Publication
25306215 | J:217168
 
First Author: Stellas D
Year: 2014
Journal: J Natl Cancer Inst
Title: Therapeutic effects of an anti-Myc drug on mouse pancreatic cancer.
Volume: 106
Issue: 12
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Publication
35216965 | J:350085
First Author: Garcia Garcia CJ
Year: 2022
Journal: Gastroenterology
Title: Stromal HIF2 Regulates Immune Suppression in the Pancreatic Cancer Microenvironment.
Volume: 162
Issue: 7
Pages: 2018-2031
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Publication
34009137 | J:308022
First Author: Flowers BM
Year: 2021
Journal: Cancer Discov
Title: Cell of Origin Influences Pancreatic Cancer Subtype.
Volume: 11
Issue: 3
Pages: 660-677
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Publication
24550494 | J:207404
First Author: Ischenko I
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Analysis of the tumor-initiating and metastatic capacity of PDX1-positive cells from the adult pancreas.
Volume: 111
Issue: 9
Pages: 3466-71
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Publication
29588349 | J:262590
First Author: Vreka M
Year: 2018
Journal: Cancer Res
Title: IκB Kinase α Is Required for Development and Progression of KRAS-Mutant Lung Adenocarcinoma.
Volume: 78
Issue: 11
Pages: 2939-2951
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Publication
19648963 | J:153756
First Author: Kelly-Spratt KS
Year: 2009
Journal: Oncogene
Title: Inhibition of PI-3K restores nuclear p27Kip1 expression in a mouse model of Kras-driven lung cancer.
Volume: 28
Issue: 41
Pages: 3652-62
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Publication
30952657 | J:276349
First Author: Poulin EJ
Year: 2019
Journal: Cancer Discov
Title: Tissue-Specific Oncogenic Activity of KRASA146T.
Volume: 9
Issue: 6
Pages: 738-755
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Publication
36548081 | J:333347
 
First Author: Zhang S
Year: 2023
Journal: J Clin Invest
Title: The UBE2C/CDH1/DEPTOR axis is an oncogene and tumor suppressor cascade in lung cancer cells.
Volume: 133
Issue: 4
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Publication
16585505 | J:108298
First Author: Bardeesy N
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse.
Volume: 103
Issue: 15
Pages: 5947-52
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Publication
34380768 | J:317185
 
First Author: Martinez-Usatorre A
Year: 2021
Journal: Sci Transl Med
Title: Overcoming microenvironmental resistance to PD-1 blockade in genetically engineered lung cancer models.
Volume: 13
Issue: 606
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Publication
20018721 | J:156461
First Author: Morton JP
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer.
Volume: 107
Issue: 1
Pages: 246-51
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Publication
24859528 | J:227613
First Author: Li X
Year: 2014
Journal: Nat Med
Title: Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture.
Volume: 20
Issue: 7
Pages: 769-77
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Publication
21042537 | J:166709
First Author: Mazur PK
Year: 2010
Journal: PLoS One
Title: Identification of epidermal Pdx1 expression discloses different roles of Notch1 and Notch2 in murine Kras(G12D)-induced skin carcinogenesis in vivo.
Volume: 5
Issue: 10
Pages: e13578
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Publication
29490942 | J:262303
First Author: Sangrador I
Year: 2018
Journal: Cancer Res
Title: Zeb1 in Stromal Myofibroblasts Promotes Kras-Driven Development of Pancreatic Cancer.
Volume: 78
Issue: 10
Pages: 2624-2637
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Publication
18725219 | J:142261
First Author: Heiser PW
Year: 2008
Journal: Gastroenterology
Title: Stabilization of beta-catenin induces pancreas tumor formation.
Volume: 135
Issue: 4
Pages: 1288-300
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Publication
20071774 | J:156681
First Author: Morris JP 4th
Year: 2010
Journal: J Clin Invest
Title: Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice.
Volume: 120
Issue: 2
Pages: 508-20
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Publication
28279655 | J:241941
First Author: Jungnickel C
Year: 2017
Journal: Am J Pathol
Title: Nontypeable Haemophilus influenzae-Promoted Proliferation of Kras-Induced Early Adenomatous Lesions Is Completely Dependent on Toll-Like Receptor Signaling.
Volume: 187
Issue: 5
Pages: 973-979
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Publication
36715544 | J:334469
First Author: Stein BD
Year: 2023
Journal: Cancer Discov
Title: LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma.
Volume: 13
Issue: 4
Pages: 1002-1025
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Publication
34006524 | J:307155
First Author: Deneka AY
Year: 2021
Journal: Cancer Res
Title: Nedd9 Restrains Autophagy to Limit Growth of Early Stage Non-Small Cell Lung Cancer.
Volume: 81
Issue: 13
Pages: 3717-3726
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Publication
34998392 | J:338506
First Author: Saliakoura M
Year: 2022
Journal: J Exp Clin Cancer Res
Title: Restriction of extracellular lipids renders pancreatic cancer dependent on autophagy.
Volume: 41
Issue: 1
Pages: 16
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Publication
33972443 | J:306300
 
First Author: Tien JC
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: AGO2 promotes tumor progression in KRAS-driven mouse models of non-small cell lung cancer.
Volume: 118
Issue: 20
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27643638 | J:240510
First Author: Svensson RU
Year: 2016
Journal: Nat Med
Title: Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models.
Volume: 22
Issue: 10
Pages: 1108-1119
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32586050 | J:305914
 
First Author: Hsieh MJ
Year: 2020
Journal: Int J Mol Sci
Title: Inactivation of APC Induces CD34 Upregulation to Promote Epithelial-Mesenchymal Transition and Cancer Stem Cell Traits in Pancreatic Cancer.
Volume: 21
Issue: 12
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26168291 | J:228762
First Author: Nassar D
Year: 2015
Journal: Nat Med
Title: Genomic landscape of carcinogen-induced and genetically induced mouse skin squamous cell carcinoma.
Volume: 21
Issue: 8
Pages: 946-54
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24737325 | J:349074
First Author: Mills LD
Year: 2014
Journal: J Biol Chem
Title: Inactivation of the transcription factor GLI1 accelerates pancreatic cancer progression.
Volume: 289
Issue: 23
Pages: 16516-25
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32157212 | J:297887
First Author: Arnal-Estapé A
Year: 2020
Journal: Oncogene
Title: Tumor progression and chromatin landscape of lung cancer are regulated by the lineage factor GATA6.
Volume: 39
Issue: 18
Pages: 3726-3737
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Publication
26567140 | J:227253
First Author: Green S
Year: 2015
Journal: Cancer Res
Title: PIK3CA(H1047R) Accelerates and Enhances KRAS(G12D)-Driven Lung Tumorigenesis.
Volume: 75
Issue: 24
Pages: 5378-91
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Publication
38473403 | J:346080
 
First Author: Fang KT
Year: 2024
Journal: Cancers (Basel)
Title: Haploinsufficiency of Adenomatous Polyposis Coli Coupled with Kirsten Rat Sarcoma Viral Oncogene Homologue Activation and P53 Loss Provokes High-Grade Glioblastoma Formation in Mice.
Volume: 16
Issue: 5
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29447458 | J:279130
First Author: Sinkevicius KW
Year: 2018
Journal: Am J Respir Cell Mol Biol
Title: E-Cadherin Loss Accelerates Tumor Progression and Metastasis in a Mouse Model of Lung Adenocarcinoma.
Volume: 59
Issue: 2
Pages: 237-245
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36702816 | J:332808
First Author: Bhatt V
Year: 2023
Journal: Cell Death Dis
Title: Inhibition of autophagy and MEK promotes ferroptosis in Lkb1-deficient Kras-driven lung tumors.
Volume: 14
Issue: 1
Pages: 61
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29892061 | J:271617
First Author: Lissanu Deribe Y
Year: 2018
Journal: Nat Med
Title: Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer.
Volume: 24
Issue: 7
Pages: 1047-1057
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18676835 | J:140034
First Author: Macias-Perez I
Year: 2008
Journal: Cancer Res
Title: Loss of integrin alpha1beta1 ameliorates Kras-induced lung cancer.
Volume: 68
Issue: 15
Pages: 6127-35
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30515799 | J:320879
First Author: Amit M
Year: 2019
Journal: Int J Cancer
Title: RET, a targetable driver of pancreatic adenocarcinoma.
Volume: 144
Issue: 12
Pages: 3014-3022
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23918374 | J:200917
First Author: Aytes A
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer.
Volume: 110
Issue: 37
Pages: E3506-15
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34475109 | J:312347
First Author: Kodama M
Year: 2021
Journal: Cancer Res
Title: Sleeping Beauty Transposon Mutagenesis Identifies Genes Driving the Initiation and Metastasis of Uterine Leiomyosarcoma.
Volume: 81
Issue: 21
Pages: 5413-5424
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32990679 | J:296368
 
First Author: Wong JC
Year: 2020
Journal: JCI Insight
Title: KrasP34R and KrasT58I mutations induce distinct RASopathy phenotypes in mice.
Volume: 5
Issue: 21
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33512434 | J:307795
First Author: Wen Z
Year: 2021
Journal: Blood
Title: Nras Q61R/+ and Kras-/- cooperate to downregulate Rasgrp1 and promote lympho-myeloid leukemia in early T-cell precursors.
Volume: 137
Issue: 23
Pages: 3259-3271
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25043045 | J:217109
First Author: Saha SK
Year: 2014
Journal: Nature
Title: Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer.
Volume: 513
Issue: 7516
Pages: 110-4
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32200350 | J:288996
First Author: Muthalagu N
Year: 2020
Journal: Cancer Discov
Title: Repression of the Type I Interferon Pathway Underlies MYC- and KRAS-Dependent Evasion of NK and B Cells in Pancreatic Ductal Adenocarcinoma.
Volume: 10
Issue: 6
Pages: 872-887
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22052106 | J:320501
First Author: DiNorcia J
Year: 2012
Journal: J Gastrointest Surg
Title: RAGE gene deletion inhibits the development and progression of ductal neoplasia and prolongs survival in a murine model of pancreatic cancer.
Volume: 16
Issue: 1
Pages: 104-12; discussion 112
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21926469 | J:178489
First Author: Ijichi H
Year: 2011
Journal: J Clin Invest
Title: Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma.
Volume: 121
Issue: 10
Pages: 4106-17
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28894253 | J:255708
First Author: Drosos Y
Year: 2017
Journal: Sci Rep
Title: ATM-deficiency increases genomic instability and metastatic potential in a mouse model of pancreatic cancer.
Volume: 7
Issue: 1
Pages: 11144
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33244070 | J:299705
First Author: Layeghi-Ghalehsoukhteh S
Year: 2020
Journal: Sci Rep
Title: Concerted cell and in vivo screen for pancreatic ductal adenocarcinoma (PDA) chemotherapeutics.
Volume: 10
Issue: 1
Pages: 20662
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26257060 | J:233987
First Author: Taki K
Year: 2016
Journal: Oncogene
Title: GNAS(R201H) and Kras(G12D) cooperate to promote murine pancreatic tumorigenesis recapitulating human intraductal papillary mucinous neoplasm.
Volume: 35
Issue: 18
Pages: 2407-12
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24395249 | J:205582
First Author: Saborowski M
Year: 2014
Journal: Genes Dev
Title: A modular and flexible ESC-based mouse model of pancreatic cancer.
Volume: 28
Issue: 1
Pages: 85-97
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Publication
33077574 | J:349058
First Author: Singh A
Year: 2021
Journal: Clin Cancer Res
Title: NRF2 Activation Promotes Aggressive Lung Cancer and Associates with Poor Clinical Outcomes.
Volume: 27
Issue: 3
Pages: 877-888
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24292713 | J:207625
First Author: Glasauer A
Year: 2014
Journal: J Clin Invest
Title: Targeting SOD1 reduces experimental non–small-cell lung cancer.
Volume: 124
Issue: 1
Pages: 117-28
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Publication
33983114 | J:314151
   
First Author: Liu S
Year: 2021
Journal: Elife
Title: Single-PanIN-seq unveils that ARID1A deficiency promotes pancreatic tumorigenesis by attenuating KRAS-induced senescence.
Volume: 10
•
•
•
•
•
Publication
34922945 | J:322176
First Author: Costamagna A
Year: 2022
Journal: Gastroenterology
Title: Docking Protein p130Cas Regulates Acinar to Ductal Metaplasia During Pancreatic Adenocarcinoma Development and Pancreatitis.
Volume: 162
Issue: 4
Pages: 1242-1255.e11
•
•
•
•
•
Publication
34526722 | J:325768
First Author: Neuhöfer P
Year: 2021
Journal: Nature
Title: Acinar cell clonal expansion in pancreas homeostasis and carcinogenesis.
Volume: 597
Issue: 7878
Pages: 715-719
•
•
•
•
•
Publication
30705405 | J:278756
First Author: Nishikawa Y
Year: 2019
Journal: Oncogene
Title: Hes1 plays an essential role in Kras-driven pancreatic tumorigenesis.
Volume: 38
Issue: 22
Pages: 4283-4296
•
•
•
•
•
Publication
25622904 | J:244951
First Author: Tan M
Year: 2015
Journal: Neoplasia
Title: Inactivation of Sag/Rbx2/Roc2 e3 ubiquitin ligase triggers senescence and inhibits kras-induced immortalization.
Volume: 17
Issue: 1
Pages: 114-23
•
•
•
•
•
Publication
34987057 | J:321472
First Author: Liu X
Year: 2022
Journal: Cancer Res
Title: Chromatin Remodeling Induced by ARID1A Loss in Lung Cancer Promotes Glycolysis and Confers JQ1 Vulnerability.
Volume: 82
Issue: 5
Pages: 791-804
•
•
•
•
•
Publication
22549877 | J:316630
First Author: Liao J
Year: 2013
Journal: Mol Carcinog
Title: Atorvastatin inhibits pancreatic carcinogenesis and increases survival in LSL-KrasG12D-LSL-Trp53R172H-Pdx1-Cre mice.
Volume: 52
Issue: 9
Pages: 739-50
•
•
•
•
•
Publication
35091677 | J:321224
First Author: Meinhardt AL
Year: 2022
Journal: Oncogene
Title: The BCL-2 family member BOK promotes KRAS-driven lung cancer progression in a p53-dependent manner.
Volume: 41
Issue: 9
Pages: 1376-1382
•
•
•
•
•
Publication
32561656 | J:300427
First Author: Huang J
Year: 2020
Journal: Mol Cancer Res
Title: The Long Noncoding RNA NEAT1 Promotes Sarcoma Metastasis by Regulating RNA Splicing Pathways.
Volume: 18
Issue: 10
Pages: 1534-1544
•
•
•
•
•
Publication
28453558 | J:245946
First Author: Deneka AY
Year: 2017
Journal: PLoS One
Title: Tumor-targeted SN38 inhibits growth of early stage non-small cell lung cancer (NSCLC) in a KRas/p53 transgenic mouse model.
Volume: 12
Issue: 4
Pages: e0176747
•
•
•
•
•
Publication
31903163 | J:298338
First Author: Novitskiy SV
Year: 2019
Journal: Oncotarget
Title: Gas6/MerTK signaling is negatively regulated by NF-κB and supports lung carcinogenesis.
Volume: 10
Issue: 66
Pages: 7031-7042
•
•
•
•
•
Publication
32432338 | J:298110
First Author: Riera KM
Year: 2020
Journal: J Pathol
Title: Trop2 is upregulated in the transition to dysplasia in the metaplastic gastric mucosa.
Volume: 251
Issue: 3
Pages: 336-347
•
•
•
•
•
Publication
23999170 | J:310011
First Author: Delgiorno KE
Year: 2014
Journal: Gastroenterology
Title: Identification and manipulation of biliary metaplasia in pancreatic tumors.
Volume: 146
Issue: 1
Pages: 233-44.e5
•
•
•
•
•
Publication
37543088 | J:341112
First Author: Pan L
Year: 2023
Journal: Cell Mol Gastroenterol Hepatol
Title: RBPJ Deficiency Sensitizes Pancreatic Acinar Cells to KRAS-Mediated Pancreatic Intraepithelial Neoplasia Initiation.
Volume: 16
Issue: 5
Pages: 783-807
•
•
•
•
•
Publication
38924548 | J:350485
First Author: Brunet M
Year: 2024
Journal: J Pathol
Title: The E3 ubiquitin ligase TRIP12 is required for pancreatic acinar cell plasticity and pancreatic carcinogenesis.
Volume: 263
Issue: 4-5
Pages: 466-481
•
•
•
•
•
Publication
23689354 | J:200524
First Author: Li H
Year: 2013
Journal: Carcinogenesis
Title: Sulindac inhibits pancreatic carcinogenesis in LSL-KrasG12D-LSL-Trp53R172H-Pdx-1-Cre mice via suppressing aldo-keto reductase family 1B10 (AKR1B10).
Volume: 34
Issue: 9
Pages: 2090-8
•
•
•
•
•




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