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Search results 501 to 588 out of 588 for Lrat

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4424567
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824770
Age: embryonic day 14.5
Image: euxassay_012212_18
Specimen Label: euxassay_012212_18
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
 
Probe: MGI:4424567
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824770
Age: embryonic day 14.5
Image: euxassay_012212_19
Specimen Label: euxassay_012212_19
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
 
Probe: MGI:4424567
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1794223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824770
Age: embryonic day 14.5
Image: euxassay_012212_04
Specimen Label: euxassay_012212_04
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4424567
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1794223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824770
Age: embryonic day 14.5
Image: euxassay_012212_17
Specimen Label: euxassay_012212_17
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
     
Probe: MGI:1368750
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754722
Stage: TS22
Assay Id: MGI:4354944
Age: embryonic day 14.5
Specimen Label: Table S5 - AW125753
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4424567
Assay Type: RNA in situ
Annotation Date: 2024-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7576069
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:1368750
Assay Type: RNA in situ
Annotation Date: 2024-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7576092
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4424567
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1788623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824770
Age: embryonic day 14.5
Image: euxassay_012212_05
Specimen Label: euxassay_012212_05
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:4424567
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1702123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824770
Age: embryonic day 14.5
Image: euxassay_012212_06
Specimen Label: euxassay_012212_06
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:4424567
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1702123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824770
Age: embryonic day 14.5
Image: euxassay_012212_07
Specimen Label: euxassay_012212_07
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:3514255
Assay Type: RNA in situ
Annotation Date: 2005-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3514347
Age: embryonic day 13.0
Image: 1C E13.0
Specimen Label: 1C E13.0
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3514255
Assay Type: RNA in situ
Annotation Date: 2005-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:3514347
Age: embryonic day 17.0
Image: 1C E17.0
Specimen Label: 1C E17.0
Detected: true
Specimen Num: 2
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Allele
Lratd1<tm1e(KOMP)Wtsi> | MGI:4419971
Name: LRAT domain containing 1; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Lratd1<tm2e(KOMP)Wtsi> | MGI:4452674
Name: LRAT domain containing 1; targeted mutation 2e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Lratd1<tm2a(KOMP)Wtsi> | MGI:4452693
Name: LRAT domain containing 1; targeted mutation 2a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Lratd2<em1(IMPC)Ccpcz> | MGI:6316150
Name: LRAT domain containing 1; endonuclease-mediated mutation 1, Institute of Molecular Genetics
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Lrat/Lrat
Background: involves: 129S6/SvEvTac
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0110188 | Leber congenital amaurosis 14
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Publication
30526553 | J:308845
First Author: Homer-Bouthiette C
Year: 2018
Journal: BMC Cancer
Title: Deletion of the murine ortholog of the 8q24 gene desert has anti-cancer effects in transgenic mammary cancer models.
Volume: 18
Issue: 1
Pages: 1233
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Strain
MGI:6335833 | C57BL/6NCrl-Lratd2<em1(IMPC)Ccpcz>/Ph
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6460941 | C57BL/6N-Lratd2<em1(IMPC)Ccpcz>/Ccpcz
Attribute String: coisogenic, targeted mutation
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Genotype
Genotype
Symbol: Lratd2/Lratd2
Background: C57BL/6N-Lratd2/Ccpcz
Zygosity: hm
Has Mutant Allele: true
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Allele
Lrat<em1(cre)Smoc> | MGI:6514033
Name: lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase); endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Recombinase
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HT Experiment
E-GEOD-74905 | Effects of vitamin A on Ventricular myocardium gene expression [right ventricle]
Series Id: GSE74905
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Strain
MGI:7461607 | C57BL/6JSmoc-Lrat<em1(cre)Smoc>/SmocKmpc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:6429120 | C57BL/6JSmoc-Lrat<em1(cre)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Publication
21424122 | J:184955
First Author: Kamino H
Year: 2011
Journal: Int J Oncol
Title: Nuclear receptor CAR-regulated expression of the FAM84A gene during the development of mouse liver tumors.
Volume: 38
Issue: 6
Pages: 1511-20
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HT Experiment
E-GEOD-74904 | Effects of vitamin A on ventricular myocardium gene expression [left ventricle]
Series Id: GSE74904
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Allele
Tg(Lrat-cre)1Rshw | MGI:5545650
Name: transgene insertion 1, Robert F Schwabe
Allele Type: Transgenic
Attribute String: Recombinase
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Strain
MGI:6861811 | B6.Cg-Tg(Lrat-cre)1Rshw/Mmjax
Attribute String: congenic, mutant strain, transgenic
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Publication
38340725 | J:350705
First Author: Fondevila MF
Year: 2024
Journal: Cell Rep Med
Title: p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway.
Volume: 5
Issue: 2
Pages: 101401
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Publication
39654034 | J:360734
First Author: Liu S
Year: 2024
Journal: J Cell Mol Med
Title: Aryl Hydrocarbon Receptor Alleviates Hepatic Fibrosis by Inducing Hepatic Stellate Cell Ferroptosis.
Volume: 28
Issue: 23
Pages: e70278
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Publication
33706013 | J:306307
First Author: Hoffmann S
Year: 2021
Journal: Biochim Biophys Acta Gene Regul Mech
Title: Network-driven discovery yields new insight into Shox2-dependent cardiac rhythm control.
Volume: 1864
Issue: 4-5
Pages: 194702
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Publication
35662287 | J:358001
First Author: Kim SM
Year: 2022
Journal: Exp Mol Med
Title: Hyaluronan synthase 2, a target of miR-200c, promotes carbon tetrachloride-induced acute and chronic liver inflammation via regulation of CCL3 and CCL4.
Volume: 54
Issue: 6
Pages: 739-752
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Publication
37463576 | J:341066
First Author: Rho H
Year: 2023
Journal: Cell Metab
Title: Hexokinase 2-mediated gene expression via histone lactylation is required for hepatic stellate cell activation and liver fibrosis.
Volume: 35
Issue: 8
Pages: 1406-1423.e8
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Publication
24859337 | J:212391
First Author: Uslu VV
Year: 2014
Journal: Nat Genet
Title: Long-range enhancers regulating Myc expression are required for normal facial morphogenesis.
Volume: 46
Issue: 7
Pages: 753-8
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Publication
36902241 | J:334248
 
First Author: Chung KJ
Year: 2023
Journal: Int J Mol Sci
Title: Analysis of the Role of Stellate Cell VCAM-1 in NASH Models in Mice.
Volume: 24
Issue: 5
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Publication
37620309 | J:339287
First Author: Otto J
Year: 2023
Journal: Cell Death Dis
Title: Expression of Cyclin E1 in hepatic stellate cells is critical for the induction and progression of liver fibrosis and hepatocellular carcinoma in mice.
Volume: 14
Issue: 8
Pages: 549
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Publication
9383334 | J:45737
 
First Author: Evans BL
Year: 1997
Journal: Mol Vis
Title: Analysis of esterification of retinoids in the retinal pigmented epithelium of the Mitf-vit (vitiligo) mutant mouse.
Volume: 3
Pages: 11
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Publication
31862954 | J:287110
First Author: Saeed A
Year: 2019
Journal: Sci Rep
Title: Farnesoid X receptor and bile acids regulate vitamin A storage.
Volume: 9
Issue: 1
Pages: 19493
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Publication
21551411 | J:181416
First Author: Hu Y
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Comparison of ocular pathologies in vitamin A-deficient mice and RPE65 gene knockout mice.
Volume: 52
Issue: 8
Pages: 5507-14
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Publication
12590612 | J:115541
First Author: Moiseyev G
Year: 2003
Journal: Biochemistry
Title: Retinyl esters are the substrate for isomerohydrolase.
Volume: 42
Issue: 7
Pages: 2229-38
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Publication
20876139 | J:165400
First Author: Moiseyev G
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Inhibition of the visual cycle by A2E through direct interaction with RPE65 and implications in Stargardt disease.
Volume: 107
Issue: 41
Pages: 17551-6
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Publication
38582490 | J:347881
 
First Author: Pan X
Year: 2024
Journal: Metabolism
Title: Krüppel-like factor 10 protects against metabolic dysfunction-associated steatohepatitis by regulating HNF4α-mediated metabolic pathways.
Volume: 155
Pages: 155909
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Publication
31170413 | J:289876
First Author: Yan J
Year: 2019
Journal: Gastroenterology
Title: Aryl Hydrocarbon Receptor Signaling Prevents Activation of Hepatic Stellate Cells and Liver Fibrogenesis in Mice.
Volume: 157
Issue: 3
Pages: 793-806.e14
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Publication
36036554 | J:342536
First Author: Chowdhury K
Year: 2022
Journal: FASEB J
Title: Sirtuin 6 protects against hepatic fibrogenesis by suppressing the YAP and TAZ function.
Volume: 36
Issue: 10
Pages: e22529
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Publication
38670107 | J:349456
First Author: Isaac R
Year: 2024
Journal: Cell Metab
Title: TM7SF3 controls TEAD1 splicing to prevent MASH-induced liver fibrosis.
Volume: 36
Issue: 5
Pages: 1030-1043.e7
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Publication
34440898 | J:313560
 
First Author: Zhang W
Year: 2021
Journal: Cells
Title: Heterogeneity of Hepatic Stellate Cells in Fibrogenesis of the Liver: Insights from Single-Cell Transcriptomic Analysis in Liver Injury.
Volume: 10
Issue: 8
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Publication
26923201 | J:310889
First Author: Song G
Year: 2016
Journal: Cell Stem Cell
Title: Direct Reprogramming of Hepatic Myofibroblasts into Hepatocytes In Vivo Attenuates Liver Fibrosis.
Volume: 18
Issue: 6
Pages: 797-808
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Publication
37860002 | J:341621
 
First Author: Kandhi R
Year: 2023
Journal: Front Immunol
Title: Hepatic stellate cell-intrinsic role of SOCS1 in controlling hepatic fibrogenic response and the pro-inflammatory macrophage compartment during liver fibrosis.
Volume: 14
Pages: 1259246
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Lrat-cre)1Rshw/?
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Lrat-cre)1Rshw/?
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Lrat-cre)1Rshw/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA
Zygosity: cn
Has Mutant Allele: true
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Publication
17614941 | J:125931
First Author: Mühlfriedel S
Year: 2007
Journal: Eur J Neurosci
Title: Novel genes differentially expressed in cortical regions during late neurogenesis.
Volume: 26
Issue: 1
Pages: 33-50
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Publication
32698042 | J:327670
First Author: Saeed A
Year: 2021
Journal: Cell Mol Gastroenterol Hepatol
Title: Impaired Hepatic Vitamin A Metabolism in NAFLD Mice Leading to Vitamin A Accumulation in Hepatocytes.
Volume: 11
Issue: 1
Pages: 309-325.e3
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Publication
32027669 | J:285528
First Author: Maguire M
Year: 2020
Journal: PLoS One
Title: Cyp1b1 directs Srebp-mediated cholesterol and retinoid synthesis in perinatal liver; Association with retinoic acid activity during fetal development.
Volume: 15
Issue: 2
Pages: e0228436
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Publication
30180270 | J:325303
First Author: Inzaugarat ME
Year: 2019
Journal: Hepatology
Title: NLR Family Pyrin Domain-Containing 3 Inflammasome Activation in Hepatic Stellate Cells Induces Liver Fibrosis in Mice.
Volume: 69
Issue: 2
Pages: 845-859
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Publication
31189722 | J:279074
 
First Author: Yang YM
Year: 2019
Journal: Sci Transl Med
Title: Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis.
Volume: 11
Issue: 496
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Publication
29774570 | J:352259
First Author: Ge X
Year: 2018
Journal: Hepatology
Title: High Mobility Group Box-1 Drives Fibrosis Progression Signaling via the Receptor for Advanced Glycation End Products in Mice.
Volume: 68
Issue: 6
Pages: 2380-2404
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Publication
30445007 | J:293707
First Author: Liang S
Year: 2019
Journal: Gastroenterology
Title: NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice.
Volume: 156
Issue: 4
Pages: 1156-1172.e6
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Publication
32305562 | J:313610
First Author: Zhong X
Year: 2020
Journal: Cell Mol Gastroenterol Hepatol
Title: SIRT6 Protects Against Liver Fibrosis by Deacetylation and Suppression of SMAD3 in Hepatic Stellate Cells.
Volume: 10
Issue: 2
Pages: 341-364
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Publication
27728806 | J:236712
First Author: Duran A
Year: 2016
Journal: Cancer Cell
Title: p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer.
Volume: 30
Issue: 4
Pages: 595-609
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Publication
31982409 | J:299369
First Author: Liu X
Year: 2020
Journal: Gastroenterology
Title: Identification of Lineage-Specific Transcription Factors That Prevent Activation of Hepatic Stellate Cells and Promote Fibrosis Resolution.
Volume: 158
Issue: 6
Pages: 1728-1744.e14
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Publication
14651920 | J:86843
First Author: Easterday MC
Year: 2003
Journal: Dev Biol
Title: Neural progenitor genes. Germinal zone expression and analysis of genetic overlap in stem cell populations.
Volume: 264
Issue: 2
Pages: 309-22
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Publication
29091291 | J:317536
First Author: Caviglia JM
Year: 2018
Journal: Hepatology
Title: MicroRNA-21 and Dicer are dispensable for hepatic stellate cell activation and the development of liver fibrosis.
Volume: 67
Issue: 6
Pages: 2414-2429
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Publication
35385339 | J:326757
First Author: Mederacke I
Year: 2022
Journal: Sci Transl Med
Title: The purinergic P2Y14 receptor links hepatocyte death to hepatic stellate cell activation and fibrogenesis in the liver.
Volume: 14
Issue: 639
Pages: eabe5795
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Publication
38309273 | J:345926
First Author: Savage TM
Year: 2024
Journal: Immunity
Title: Amphiregulin from regulatory T cells promotes liver fibrosis and insulin resistance in non-alcoholic steatohepatitis.
Volume: 57
Issue: 2
Pages: 303-318.e6
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Publication
36198802 | J:339972
First Author: Filliol A
Year: 2022
Journal: Nature
Title: Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis.
Volume: 610
Issue: 7931
Pages: 356-365
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Publication
24264436 | J:205330
 
First Author: Mederacke I
Year: 2013
Journal: Nat Commun
Title: Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology.
Volume: 4
Pages: 2823
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Publication
37676943 | J:358242
First Author: Peiseler M
Year: 2023
Journal: Science
Title: Kupffer cell-like syncytia replenish resident macrophage function in the fibrotic liver.
Volume: 381
Issue: 6662
Pages: eabq5202
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Publication
37338984 | J:360059
 
First Author: Feng D
Year: 2023
Journal: J Clin Invest
Title: Monocyte-derived macrophages orchestrate multiple cell-type interactions to repair necrotic liver lesions in disease models.
Volume: 133
Issue: 15
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Publication
33930309 | J:306524
First Author: Affo S
Year: 2021
Journal: Cancer Cell
Title: Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations.
Volume: 39
Issue: 6
Pages: 866-882.e11
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Publication
19521500 | J:149737
First Author: Sansom SN
Year: 2009
Journal: PLoS Genet
Title: The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
Volume: 5
Issue: 6
Pages: e1000511
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
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First Author: Mouse Genome Informatics Scientific Curators
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Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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First Author: MGD Nomenclature Committee
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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