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Search results 501 to 600 out of 851 for Lrp2

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Hits by Strain

Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:4949862
Assay Type: Immunohistochemistry
Annotation Date: 2014-03-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2801123
Stage: TS23
Assay Id: MGI:5548303
Age: embryonic day 15.5
Image: GUDMAP:8201
Specimen Label: GUDMAP:8201
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5299067
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:2801128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5543051
Age: postnatal day 84
Image: GUDMAP:14452
Specimen Label: GUDMAP:14452
Specimen Num: 2
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Publication
10766831 | J:67664
First Author: Hammad SM
Year: 2000
Journal: J Biol Chem
Title: Megalin acts in concert with cubilin to mediate endocytosis of high density lipoproteins.
Volume: 275
Issue: 16
Pages: 12003-8
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Publication
14983511 | J:88400
First Author: Drake CJ
Year: 2004
Journal: Anat Rec A Discov Mol Cell Evol Biol
Title: Differential distribution of cubilin and megalin expression in the mouse embryo.
Volume: 277
Issue: 1
Pages: 163-70
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Publication
15616221 | J:98256
First Author: Assémat E
Year: 2005
Journal: Biol Reprod
Title: Expression and role of cubilin in the internalization of nutrients during the peri-implantation development of the rodent embryo.
Volume: 72
Issue: 5
Pages: 1079-86
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Publication
16099815 | J:104065
First Author: Faber K
Year: 2006
Journal: Mol Endocrinol
Title: Megalin is a receptor for apolipoprotein M, and kidney-specific megalin-deficiency confers urinary excretion of apolipoprotein M.
Volume: 20
Issue: 1
Pages: 212-8
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Publication
17462596 | J:121774
First Author: Kaseda R
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Megalin-mediated endocytosis of cystatin C in proximal tubule cells.
Volume: 357
Issue: 4
Pages: 1130-4
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Publication
23825075 | J:200932
First Author: Jobst-Schwan T
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Renal uptake of the antiapoptotic protein survivin is mediated by megalin at the apical membrane of the proximal tubule.
Volume: 305
Issue: 5
Pages: F734-44
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Publication
27773703 | J:251304
First Author: Hirano M
Year: 2017
Journal: Biochim Biophys Acta
Title: N-Glycoform-dependent interactions of megalin with its ligands.
Volume: 1861
Issue: 1 Pt A
Pages: 3106-3118
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Publication
28659595 | J:243418
First Author: Johanns M
Year: 2017
Journal: Sci Rep
Title: Cellular uptake of proMMP-2:TIMP-2 complexes by the endocytic receptor megalin/LRP-2.
Volume: 7
Issue: 1
Pages: 4328
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Publication
19279259 | J:147068
First Author: Fleming CE
Year: 2009
Journal: J Neurosci
Title: Transthyretin internalization by sensory neurons is megalin mediated and necessary for its neuritogenic activity.
Volume: 29
Issue: 10
Pages: 3220-32
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Publication
17369355 | J:120117
First Author: Nielsen R
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells.
Volume: 104
Issue: 13
Pages: 5407-12
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Publication
24980834 | J:315754
First Author: Storm T
Year: 2014
Journal: Cell Tissue Res
Title: Megalin-deficiency causes high myopia, retinal pigment epithelium-macromelanosomes and abnormal development of the ciliary body in mice.
Volume: 358
Issue: 1
Pages: 99-107
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Publication
27796299 | J:242634
 
First Author: Barasch J
Year: 2016
Journal: Nat Commun
Title: Disposal of iron by a mutant form of lipocalin 2.
Volume: 7
Pages: 12973
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Publication
28351841 | J:247839
First Author: Arora K
Year: 2017
Journal: FASEB J
Title: Maternofetal transport of vitamin B12: role of TCblR/CD320 and megalin.
Volume: 31
Issue: 7
Pages: 3098-3106
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Publication
23430977 | J:199961
First Author: Lai SC
Year: 2013
Journal: FASEB J
Title: The transcobalamin receptor knockout mouse: a model for vitamin B12 deficiency in the central nervous system.
Volume: 27
Issue: 6
Pages: 2468-75
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Publication
10556425 | J:58190
First Author: Bouchard G
Year: 1999
Journal: Mamm Genome
Title: High-resolution maps of the murine Chromosome 2 region containing the cholesterol gallstone locus, Lith1.
Volume: 10
Issue: 11
Pages: 1070-4
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Publication
9546356 | J:46905
First Author: Moll S
Year: 1998
Journal: Am J Pathol
Title: Tubular up-regulation of clusterin mRNA in murine lupus-like nephritis.
Volume: 152
Issue: 4
Pages: 953-62
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Publication
10665926 | J:103160
First Author: Birn H
Year: 2000
Journal: J Am Soc Nephrol
Title: Receptor-associated protein is important for normal processing of megalin in kidney proximal tubules.
Volume: 11
Issue: 2
Pages: 191-202
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Publication
18005667 | J:136759
First Author: Zhang H
Year: 2008
Journal: Biochim Biophys Acta
Title: Core 2 GlcNAc modification and megalin ligand-binding activity.
Volume: 1780
Issue: 3
Pages: 479-85
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Publication
15342463 | J:98337
First Author: Strope S
Year: 2004
Journal: Development
Title: Mouse amnionless, which is required for primitive streak assembly, mediates cell-surface localization and endocytic function of cubilin on visceral endoderm and kidney proximal tubules.
Volume: 131
Issue: 19
Pages: 4787-95
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Publication
18174160 | J:133662
First Author: Olson GE
Year: 2008
Journal: J Biol Chem
Title: Megalin mediates selenoprotein P uptake by kidney proximal tubule epithelial cells.
Volume: 283
Issue: 11
Pages: 6854-60
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Publication
27518433 | J:258912
First Author: Gomes JR
Year: 2016
Journal: Cell Death Differ
Title: Transthyretin provides trophic support via megalin by promoting neurite outgrowth and neuroprotection in cerebral ischemia.
Volume: 23
Issue: 11
Pages: 1749-1764
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Publication
12748857 | J:106203
First Author: Bacic D
Year: 2003
Journal: Pflugers Arch
Title: Impaired PTH-induced endocytotic down-regulation of the renal type IIa Na+/Pi-cotransporter in RAP-deficient mice with reduced megalin expression.
Volume: 446
Issue: 4
Pages: 475-84
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Publication
33069809 | J:299817
 
First Author: Otomo H
Year: 2020
Journal: Metabolism
Title: Sodium-glucose cotransporter 2 inhibition attenuates protein overload in renal proximal tubule via suppression of megalin O-GlcNacylation in progressive diabetic nephropathy.
Volume: 113
Pages: 154405
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Publication
10662735 | J:60362
First Author: van Hoek AN
Year: 2000
Journal: Am J Physiol Renal Physiol
Title: Aquaporin-4 is expressed in basolateral membranes of proximal tubule S3 segments in mouse kidney.
Volume: 278
Issue: 2
Pages: F310-6
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Publication
30401801 | J:268388
First Author: Shrestha S
Year: 2018
Journal: Sci Rep
Title: Circulating FABP4 is eliminated by the kidney via glomerular filtration followed by megalin-mediated reabsorption.
Volume: 8
Issue: 1
Pages: 16451
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Publication
20798259 | J:164025
First Author: Amsellem S
Year: 2010
Journal: J Am Soc Nephrol
Title: Cubilin is essential for albumin reabsorption in the renal proximal tubule.
Volume: 21
Issue: 11
Pages: 1859-67
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Publication
15870384 | J:100535
First Author: Nagai J
Year: 2005
Journal: Am J Physiol Renal Physiol
Title: Mutually dependent localization of megalin and Dab2 in the renal proximal tubule.
Volume: 289
Issue: 3
Pages: F569-76
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Publication
12815097 | J:84433
First Author: Christensen EI
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules.
Volume: 100
Issue: 14
Pages: 8472-7
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Publication
25270072 | J:302868
First Author: Pohl M
Year: 2015
Journal: J Am Soc Nephrol
Title: Short-term functional adaptation of aquaporin-1 surface expression in the proximal tubule, a component of glomerulotubular balance.
Volume: 26
Issue: 6
Pages: 1269-78
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Publication
31548351 | J:298306
First Author: Janssens V
Year: 2019
Journal: J Am Soc Nephrol
Title: Protection of Cystinotic Mice by Kidney-Specific Megalin Ablation Supports an Endocytosis-Based Mechanism for Nephropathic Cystinosis Progression.
Volume: 30
Issue: 11
Pages: 2177-2190
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Publication
16787536 | J:119685
 
First Author: Smith BT
Year: 2006
Journal: BMC Dev Biol
Title: Targeted disruption of cubilin reveals essential developmental roles in the structure and function of endoderm and in somite formation.
Volume: 6
Pages: 30
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Publication
28575050 | J:247321
First Author: Jensen D
Year: 2017
Journal: PLoS One
Title: Megalin dependent urinary cystatin C excretion in ischemic kidney injury in rats.
Volume: 12
Issue: 6
Pages: e0178796
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Publication
34370295 | J:317807
First Author: Kawakami R
Year: 2021
Journal: J Pathol
Title: Urinary FABP1 is a biomarker for impaired proximal tubular protein reabsorption and is synergistically enhanced by concurrent liver injury.
Volume: 255
Issue: 4
Pages: 362-373
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Publication
21926402 | J:181393
First Author: Weyer K
Year: 2011
Journal: Nephrol Dial Transplant
Title: Mouse model of proximal tubule endocytic dysfunction.
Volume: 26
Issue: 11
Pages: 3446-51
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Publication
32200668 | J:294299
First Author: Ren Q
Year: 2020
Journal: Am J Physiol Renal Physiol
Title: Distinct functions of megalin and cubilin receptors in recovery of normal and nephrotic levels of filtered albumin.
Volume: 318
Issue: 5
Pages: F1284-F1294
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Publication
18400109 | J:136270
 
First Author: Gelineau-van Waes J
Year: 2008
Journal: BMC Genomics
Title: Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complex.
Volume: 9
Pages: 156
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Publication
37215091 | J:338444
 
First Author: Liang S
Year: 2023
Journal: Front Cell Dev Biol
Title: Generation and characterization of an inducible renal proximal tubule-specific CreERT2 mouse.
Volume: 11
Pages: 1171637
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Publication
8244399 | J:14575
First Author: Xia YR
Year: 1993
Journal: Genomics
Title: Mapping of the glycoprotein 330 (Gp330) gene to mouse chromosome 2.
Volume: 17
Issue: 3
Pages: 780-1
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Publication
21444625 | J:180919
First Author: Schulz LC
Year: 2011
Journal: Reproduction
Title: Dynamic changes in leptin distribution in the progression from ovum to blastocyst of the pre-implantation mouse embryo.
Volume: 141
Issue: 6
Pages: 767-77
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Publication
23836931 | J:201520
First Author: Shah M
Year: 2013
Journal: J Cell Biol
Title: ARH directs megalin to the endocytic recycling compartment to regulate its proteolysis and gene expression.
Volume: 202
Issue: 1
Pages: 113-27
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Publication
30025861 | J:267032
 
First Author: Jakovac H
Year: 2018
Journal: Neuroscience
Title: Expression Profiles of Metallothionein I/II and Megalin in Cuprizone Model of De- and Remyelination.
Volume: 388
Pages: 69-86
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Publication
26206087 | J:240374
First Author: Causeret F
Year: 2016
Journal: Cell Death Differ
Title: Kremen1 and Dickkopf1 control cell survival in a Wnt-independent manner.
Volume: 23
Issue: 2
Pages: 323-32
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Publication
10772929 | J:273590
First Author: Muramatsu H
Year: 2000
Journal: Biochem Biophys Res Commun
Title: LDL receptor-related protein as a component of the midkine receptor.
Volume: 270
Issue: 3
Pages: 936-41
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Publication
19177150 | J:168293
First Author: Nada S
Year: 2009
Journal: EMBO J
Title: The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes.
Volume: 28
Issue: 5
Pages: 477-89
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Publication
12413896 | J:79862
First Author: Yang DH
Year: 2002
Journal: Dev Biol
Title: Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis.
Volume: 251
Issue: 1
Pages: 27-44
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Publication
16263760 | J:103780
First Author: Maurer ME
Year: 2005
Journal: J Cell Sci
Title: Endocytosis of megalin by visceral endoderm cells requires the Dab2 adaptor protein.
Volume: 118
Issue: Pt 22
Pages: 5345-55
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Publication
20048263 | J:296099
First Author: Follit JA
Year: 2010
Journal: J Cell Biol
Title: The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence.
Volume: 188
Issue: 1
Pages: 21-8
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Publication
17283184 | J:168197
First Author: Dubreuil V
Year: 2007
Journal: J Cell Biol
Title: Midbody and primary cilium of neural progenitors release extracellular membrane particles enriched in the stem cell marker prominin-1.
Volume: 176
Issue: 4
Pages: 483-95
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Publication
20637285 | J:171318
First Author: Alvira-Botero X
Year: 2010
Journal: Mol Cell Neurosci
Title: Megalin interacts with APP and the intracellular adapter protein FE65 in neurons.
Volume: 45
Issue: 3
Pages: 306-15
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Publication
30567480 | J:291381
First Author: Ye F
Year: 2019
Journal: Arterioscler Thromb Vasc Biol
Title: Angiotensinogen and Megalin Interactions Contribute to Atherosclerosis-Brief Report.
Volume: 39
Issue: 2
Pages: 150-155
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Publication
24760755 | J:216630
First Author: Burk RF
Year: 2014
Journal: FASEB J
Title: Selenoprotein P and apolipoprotein E receptor-2 interact at the blood-brain barrier and also within the brain to maintain an essential selenium pool that protects against neurodegeneration.
Volume: 28
Issue: 8
Pages: 3579-88
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Publication
24434121 | J:211934
 
First Author: Kurokawa S
Year: 2014
Journal: Free Radic Biol Med
Title: Sepp1(UF) forms are N-terminal selenoprotein P truncations that have peroxidase activity when coupled with thioredoxin reductase-1.
Volume: 69
Pages: 67-76
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Publication
23651543 | J:203560
First Author: Burk RF
Year: 2013
Journal: FASEB J
Title: Maternal-fetal transfer of selenium in the mouse.
Volume: 27
Issue: 8
Pages: 3249-56
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Publication
24950692 | J:214979
First Author: Sutter I
Year: 2014
Journal: J Lipid Res
Title: Apolipoprotein M modulates erythrocyte efflux and tubular reabsorption of sphingosine-1-phosphate.
Volume: 55
Issue: 8
Pages: 1730-7
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Publication
18388738 | J:136621
First Author: Wicher G
Year: 2008
Journal: Neuroreport
Title: Megalin deficiency induces critical changes in mouse spinal cord development.
Volume: 19
Issue: 5
Pages: 559-63
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Publication
18322545 | J:152876
First Author: Gailly P
Year: 2008
Journal: Kidney Int
Title: A novel renal carbonic anhydrase type III plays a role in proximal tubule dysfunction.
Volume: 74
Issue: 1
Pages: 52-61
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Publication
29032953 | J:294376
First Author: Weyer K
Year: 2018
Journal: Kidney Int
Title: Abolishment of proximal tubule albumin endocytosis does not affect plasma albumin during nephrotic syndrome in mice.
Volume: 93
Issue: 2
Pages: 335-342
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Publication
26786190 | J:235885
 
First Author: Chou SY
Year: 2016
Journal: Nat Commun
Title: CLIC4 regulates apical exocytosis and renal tube luminogenesis through retromer- and actin-mediated endocytic trafficking.
Volume: 7
Pages: 10412
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Publication
21938401 | J:178554
First Author: Pernot E
Year: 2011
Journal: Pflugers Arch
Title: The inositol Inpp5k 5-phosphatase affects osmoregulation through the vasopressin-aquaporin 2 pathway in the collecting system.
Volume: 462
Issue: 6
Pages: 871-83
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Publication
10535319 | J:61092
First Author: Lehtonen S
Year: 1999
Journal: Int J Dev Biol
Title: Vesicular transport and kidney development.
Volume: 43
Issue: 5
Pages: 425-33
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Publication
24740791 | J:212115
First Author: Li XC
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Mechanisms of AT1a receptor-mediated uptake of angiotensin II by proximal tubule cells: a novel role of the multiligand endocytic receptor megalin.
Volume: 307
Issue: 2
Pages: F222-33
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Publication
24586199 | J:215153
First Author: Follit JA
Year: 2014
Journal: PLoS Genet
Title: Arf4 is required for Mammalian development but dispensable for ciliary assembly.
Volume: 10
Issue: 2
Pages: e1004170
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Publication
17077144 | J:117102
First Author: Zheng B
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Essential role of RGS-PX1/sorting nexin 13 in mouse development and regulation of endocytosis dynamics.
Volume: 103
Issue: 45
Pages: 16776-81
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Publication
20357188 | J:164094
First Author: Wunderlich KA
Year: 2010
Journal: Invest Ophthalmol Vis Sci
Title: Altered expression of metallothionein-I and -II and their receptor megalin in inherited photoreceptor degeneration.
Volume: 51
Issue: 9
Pages: 4809-20
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Publication
27382987 | J:268609
First Author: Mori KP
Year: 2017
Journal: J Am Soc Nephrol
Title: Increase of Total Nephron Albumin Filtration and Reabsorption in Diabetic Nephropathy.
Volume: 28
Issue: 1
Pages: 278-289
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Publication
12370429 | J:79682
First Author: Girnun GD
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: APC-dependent suppression of colon carcinogenesis by PPARgamma.
Volume: 99
Issue: 21
Pages: 13771-6
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Publication
24277939 | J:315320
First Author: Moore R
Year: 2014
Journal: Mol Cell Biol
Title: The primitive endoderm segregates from the epiblast in β1 integrin-deficient early mouse embryos.
Volume: 34
Issue: 3
Pages: 560-72
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Publication
34463328 | J:310346
 
First Author: Mecklenburg N
Year: 2021
Journal: Development
Title: Identification of disease-relevant modulators of the SHH pathway in the developing brain.
Volume: 148
Issue: 17
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Publication
32876567 | J:296006
   
First Author: Hong M
Year: 2020
Journal: Elife
Title: Cdon mutation and fetal alcohol converge on Nodal signaling in a mouse model of holoprosencephaly.
Volume: 9
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Publication
28226240 | J:242325
   
First Author: Posfai E
Year: 2017
Journal: Elife
Title: Position- and Hippo signaling-dependent plasticity during lineage segregation in the early mouse embryo.
Volume: 6
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Publication
17339320 | J:121266
First Author: Yang DH
Year: 2007
Journal: J Biol Chem
Title: Disabled-2 is an epithelial surface positioning gene.
Volume: 282
Issue: 17
Pages: 13114-22
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Publication
16901941 | J:121998
First Author: Knipper M
Year: 2006
Journal: J Physiol
Title: Deafness in LIMP2-deficient mice due to early loss of the potassium channel KCNQ1/KCNE1 in marginal cells of the stria vascularis.
Volume: 576
Issue: Pt 1
Pages: 73-86
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Publication
15314648 | J:136795
First Author: Zarbalis K
Year: 2004
Journal: PLoS Biol
Title: A focused and efficient genetic screening strategy in the mouse: identification of mutations that disrupt cortical development.
Volume: 2
Issue: 8
Pages: E219
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Publication
19047013 | J:149003
First Author: Spoelgen R
Year: 2009
Journal: Neuroscience
Title: Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.
Volume: 158
Issue: 4
Pages: 1460-8
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Publication
16196028 | J:104562
First Author: Wicher G
Year: 2005
Journal: J Comp Neurol
Title: Low-density lipoprotein receptor-related protein (LRP)-2/megalin is transiently expressed in a subpopulation of neural progenitors in the embryonic mouse spinal cord.
Volume: 492
Issue: 2
Pages: 123-31
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Publication
10827173 | J:113901
First Author: Gotthardt M
Year: 2000
Journal: J Biol Chem
Title: Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.
Volume: 275
Issue: 33
Pages: 25616-24
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Publication
22354480 | J:183783
First Author: Ortega MC
Year: 2012
Journal: Glia
Title: Megalin mediates the influence of sonic hedgehog on oligodendrocyte precursor cell migration and proliferation during development.
Volume: 60
Issue: 6
Pages: 851-66
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Publication
30046000 | J:266356
 
First Author: Marable SS
Year: 2018
Journal: JCI Insight
Title: Hnf4a deletion in the mouse kidney phenocopies Fanconi renotubular syndrome.
Volume: 3
Issue: 14
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Publication
10469351 | J:59629
First Author: Lehtonen S
Year: 1999
Journal: Kidney Int
Title: Syntaxin 3 and Munc-18-2 in epithelial cells during kidney development.
Volume: 56
Issue: 3
Pages: 815-26
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Publication
11675412 | J:74182
First Author: Legallicier B
Year: 2001
Journal: J Am Soc Nephrol
Title: Expression of the type IV collagenase system during mouse kidney development and tubule segmentation.
Volume: 12
Issue: 11
Pages: 2358-69
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Allele
Lrp2bp<+> | MGI:3527267
   
Name: Lrp2 binding protein; wild type
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Publication
15082773 | J:90197
First Author: Marschang P
Year: 2004
Journal: Mol Cell Biol
Title: Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.
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