Search our database by keyword

Examples

Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 501 to 545 out of 545 for Map2k1

<< First < Previous | Next > Last >>

0.029s

Type

Details

Score

Transgene

MGI:3707554 | Tg(ACTB-MAP2K1*K97M)1Stl

Type:	transgene
Organism:	mouse, laboratory

•

Strain

MGI:6770921 | C57BL/6JSmoc-Map2k1<em1Smoc>/Smoc

Attribute String:

coisogenic, endonuclease-mediated mutation, mutant strain

•

HT Experiment

E-GEOD-51644 | Microarray analysis of gene expression profiles in Map2k1+/-Map2k2+/- and Map2k1flox/-Map2k2+/-Tg+/Sox2Cre placentas

Series Id:	GSE51644
Experiment Type:	transcription profiling by array
Study Type:	WT vs. Mutant
Source:	ArrayExpress

•

Allele

Tg(Scgb1a1-Map2k1*S218V*S222V)1Eli | MGI:3836054

Name:	transgene insertion 1, Jack A Elias
Allele Type:	Transgenic
Attribute String:	Inserted expressed sequence

•

Allele

Map2k1<tm1.1(Map2k1,Map2k2)Chrn> | MGI:6148037

Name:	mitogen-activated protein kinase kinase 1; targeted mutation 1.1, M Jean Charron
Allele Type:	Targeted
Attribute String:	Epitope tag, Inserted expressed sequence

•

Allele

Tg(CAG-cat,-Map2k1*)243Rbns | MGI:3822131

Name:	transgene insertion 243, Jeffrey Robbins
Allele Type:	Transgenic
Attribute String:	Conditional ready, Constitutively active, Inserted expressed sequence

•

Publication

18192500 | J:149719

First Author:	Manning CB
Year:	2008
Journal:	Am J Respir Cell Mol Biol
Title:	Targeting the MEK1 cascade in lung epithelium inhibits proliferation and fibrogenesis by asbestos.
Volume:	38
Issue:	5
Pages:	618-26

•

Allele

Map2k1<tm1(Map2k1,Map2k2)Chrn> | MGI:6148035

Name:	mitogen-activated protein kinase kinase 1; targeted mutation 1, M Jean Charron
Allele Type:	Targeted
Attribute String:	Epitope tag, Inserted expressed sequence, Null/knockout

•

Allele

Map2k1<tm1.2(Map2k2)Chrn> | MGI:6148039

Name:	mitogen-activated protein kinase kinase 1; targeted mutation 1.2, M Jean Charron
Allele Type:	Targeted
Attribute String:	Epitope tag, Inserted expressed sequence, Null/knockout

•

Allele

Tg(Myh6-Map2k1*)1Jmol | MGI:3766499

Name:	transgene insertion 1, Jeffery D Molkentin
Allele Type:	Transgenic
Attribute String:	Constitutively active, Inserted expressed sequence

•

Strain

MGI:6865830 | FVB/NJ-Tg(CAG-cat*,-Map2k1*)243Krnz/Mmmh

Attribute String:

coisogenic, mutant strain, transgenic

•

Strain

MGI:6143638 | 129.Cg-Map2k1<tm1(Map2k1,Map2k2)Chrn>/Mmnc

Attribute String:

mutant strain, congenic, targeted mutation

•

Allele

Gt(ROSA)26Sor<em1(CAG-Map2k1*K57N,-GFP)Psmi> | MGI:7709531

Name:	gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1, Patrick Smits
Allele Type:	Endonuclease-mediated
Attribute String:	Conditional ready, Inserted expressed sequence, Reporter

•

Strain

MGI:3851688 | FVB-Tg(Myh6-Map2k1*)1Jmol/J

Attribute String:

coisogenic, mutant strain, transgenic

•

Allele

Gt(ROSA)26Sor<tm3(RNAi:Map2k1,Map2k2)Rkuhn> | MGI:3785798

Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Ralf Kuhn
Allele Type:	Targeted
Attribute String:	Conditional ready, Knockdown, RMCE-ready

•

Genotype

Symbol:	Tg(Myh6-Map2k1*)1Jmol/?
Background:	involves: FVB
Zygosity:	ot
Has Mutant Allele:	true

•

Genotype

Symbol:	Tg(Myh6-Map2k1*)1Jmol/?
Background:	involves: FVB/N
Zygosity:	ot
Has Mutant Allele:	true

•

Publication

34407418 | J:310652

First Author:	Mori Y
Year:	2021
Journal:	Cell Rep
Title:	Cdc42 is required for male germline niche development in mice.
Volume:	36
Issue:	7
Pages:	109550

•

Publication

14729955 | J:149730

First Author:	Purcell NH
Year:	2004
Journal:	Mol Cell Biol
Title:	Extracellular signal-regulated kinase 2 interacts with and is negatively regulated by the LIM-only protein FHL2 in cardiomyocytes.
Volume:	24
Issue:	3
Pages:	1081-95

•

Genotype

Symbol:	Mapk1/Mapk1<+> Tg(Myh6-Map2k1*)1Jmol/?
Background:	involves: 129S2/SvPas * FVB
Zygosity:	cx
Has Mutant Allele:	true

•

Genotype

Symbol:	Mapk3/Mapk3 Tg(Myh6-Map2k1*)1Jmol/?
Background:	involves: 129/Sv * FVB/N
Zygosity:	cx
Has Mutant Allele:	true

•

Genotype

Symbol:	Gata4/Gata4 Tg(Myh6-Map2k1*)1Jmol/?
Background:	involves: 129 * C57BL/6 * FVB
Zygosity:	cx
Has Mutant Allele:	true

•

Publication

37999644 | J:345567

First Author:	Grimes KM
Year:	2024
Journal:	Am J Physiol Heart Circ Physiol
Title:	MEK1-ERK1/2 signaling regulates the cardiomyocyte non-sarcomeric actin cytoskeletal network.
Volume:	326
Issue:	1
Pages:	H180-H189

•

Publication

15096454 | J:127872

First Author:	Lips DJ
Year:	2004
Journal:	Circulation
Title:	MEK1-ERK2 signaling pathway protects myocardium from ischemic injury in vivo.
Volume:	109
Issue:	16
Pages:	1938-41

•

Allele

Map2k1<tm2.1Chrn> | MGI:6157680

Name:	mitogen-activated protein kinase kinase 1; targeted mutation 2.1, M Jean Charron
Allele Type:	Targeted
Attribute String:	Humanized sequence

•

Genotype

Symbol:	Gata4/Gata4 Tg(Myh6-Map2k1*)1Jmol/?
Background:	involves: 129S1/Sv * 129X1/SvJ * FVB
Zygosity:	cx
Has Mutant Allele:	true

•

Publication

35085550 | J:360448

First Author:	Urena F
Year:	2022
Journal:	J Biol Chem
Title:	T-cell activation decreases miRNA-15a/16 levels to promote MEK1-ERK1/2-Elk1 signaling and proliferative capacity.
Volume:	298
Issue:	3
Pages:	101634

•

Publication

30239744 | J:268918

First Author:	Inoue SI
Year:	2019
Journal:	Hum Mol Genet
Title:	C-type natriuretic peptide improves growth retardation in a mouse model of cardio-facio-cutaneous syndrome.
Volume:	28
Issue:	1
Pages:	74-83

•

Publication

24741069 | J:214674

First Author:	Gonzalez-Garcia JR
Year:	2014
Journal:	J Cell Sci
Title:	The dynamics of MAPK inactivation at fertilization in mouse eggs.
Volume:	127
Issue:	Pt 12
Pages:	2749-60

•

Publication

36907503 | J:334498

First Author:	Zhan D
Year:	2023
Journal:	Cancer Lett
Title:	Expanding individualized therapeutic options via genoproteomics.
Volume:	560

Pages:	216123

•

Publication

24706815 | J:208629

First Author:	Lajiness JD
Year:	2014
Journal:	Proc Natl Acad Sci U S A
Title:	SHP-2 deletion in postmigratory neural crest cells results in impaired cardiac sympathetic innervation.
Volume:	111
Issue:	14
Pages:	E1374-82

•

Publication

16374521 | J:105338

First Author:	Lee PJ
Year:	2006
Journal:	J Clin Invest
Title:	ERK1/2 mitogen-activated protein kinase selectively mediates IL-13-induced lung inflammation and remodeling in vivo.
Volume:	116
Issue:	1
Pages:	163-73

•

Publication

21746915 | J:174537

First Author:	van Berlo JH
Year:	2011
Journal:	Proc Natl Acad Sci U S A
Title:	Serine 105 phosphorylation of transcription factor GATA4 is necessary for stress-induced cardiac hypertrophy in vivo.
Volume:	108
Issue:	30
Pages:	12331-6

•

Strain

MGI:6157681 | STOCK Map2k1<tm2.1Chrn>/J

Attribute String:

mutant stock, targeted mutation

•

Strain

MGI:6148801 | STOCK Map2k1<tm2.1Chrn>/Mmmh

Attribute String:

mutant stock, targeted mutation

•

Genotype

Symbol:	Tg(CAG-cat,-Map2k1*)243Rbns/? Tg(Tek-cre)12Flv/?
Background:	involves: C3H * C57BL/6 * FVB/N
Zygosity:	cn
Has Mutant Allele:	true

•

Genotype

Symbol:	Gata4/Gata4 Tg(Myh6-Map2k1*)1Jmol/? Tg(Myh7-cre)1Jmk/?
Background:	involves: 129S1/Sv * 129X1/SvJ * FVB
Zygosity:	cn
Has Mutant Allele:	true

•

Genotype

Symbol:	Tg(Myh6-Map2k1)1Jmol/? Tg(Myh6/tetO-Tnnc1I61Q)1Jmol/? Tg(Myh6-tTA)55Rbns/?
Background:	involves: FVB
Zygosity:	cx
Has Mutant Allele:	true

•

Genotype

Symbol:	Map2k1/Map2k1<+>
Background:	involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL/J
Zygosity:	ht
Has Mutant Allele:	true

•

Genotype

Symbol:	Map2k1/Map2k1
Background:	involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL/J
Zygosity:	hm
Has Mutant Allele:	true

•

Genotype

Symbol:	Map2k1/Map2k1
Background:	involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL/J
Zygosity:	ht
Has Mutant Allele:	true

•

Publication

17709754 | J:124903

First Author:	Purcell NH
Year:	2007
Journal:	Proc Natl Acad Sci U S A
Title:	Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo.
Volume:	104
Issue:	35
Pages:	14074-9

•

Publication

36733907 | J:333030

First Author:	Grimes KM
Year:	2023
Journal:	Front Physiol
Title:	Rpl3l gene deletion in mice reduces heart weight over time.
Volume:	14

Pages:	1054169

•

Publication

17586814 | J:133638

First Author:	Hitz C
Year:	2007
Journal:	Nucleic Acids Res
Title:	Conditional brain-specific knockdown of MAPK using Cre/loxP regulated RNA interference.
Volume:	35
Issue:	12
Pages:	e90

•

Publication

27114035 | J:234490

First Author:	Davis J
Year:	2016
Journal:	Cell
Title:	A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy.
Volume:	165
Issue:	5
Pages:	1147-1159

•

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/keywordSearchResults.do?searchOffset=500&searchTerm=Map2k1

MouseMine

Search our database by keyword

Examples

Search results 501 to 545 out of 545 for Map2k1

Categories

Hits by Pathway

Hits by Category

Hits by Strain