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Search results 501 to 600 out of 622 for Mesp1

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Type Details Score
GXD Expression      
Probe: MGI:7569198
Assay Type: RT-PCR
Annotation Date: 2023-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7569209
Age: embryonic day 13.5
Specimen Label: Mesp1 CRE/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7569200
Assay Type: RT-PCR
Annotation Date: 2023-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7569211
Age: embryonic day 13.5
Specimen Label: Mesp1 CRE/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7569202
Assay Type: RT-PCR
Annotation Date: 2023-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7569213
Age: embryonic day 13.5
Specimen Label: Mesp1 CRE/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7569203
Assay Type: RT-PCR
Annotation Date: 2023-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7569215
Age: embryonic day 13.5
Specimen Label: Mesp1 CRE/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7569205
Assay Type: RT-PCR
Annotation Date: 2023-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7569217
Age: embryonic day 13.5
Specimen Label: Mesp1 CRE/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7569199
Assay Type: RT-PCR
Annotation Date: 2023-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7569210
Age: embryonic day 13.5
Specimen Label: Mesp1 CRE/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7569201
Assay Type: RT-PCR
Annotation Date: 2023-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7569212
Age: embryonic day 13.5
Specimen Label: Mesp1 CRE/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7328518
Assay Type: RT-PCR
Annotation Date: 2023-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7569216
Age: embryonic day 13.5
Specimen Label: Mesp1 CRE/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7569207
Assay Type: RT-PCR
Annotation Date: 2023-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7569218
Age: embryonic day 13.5
Specimen Label: Mesp1 CRE/+
Detected: true
Specimen Num: 1
Publication
First Author: Park EJ
Year: 2008
Journal: Development
Title: An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart.
Volume: 135
Issue: 21
Pages: 3599-610
Publication
First Author: Tampakakis E
Year: 2021
Journal: Sci Adv
Title: Heart neurons use clock genes to control myocyte proliferation.
Volume: 7
Issue: 49
Pages: eabh4181
Publication
First Author: Santos R
Year: 2016
Journal: PLoS Biol
Title: Conditional Creation and Rescue of Nipbl-Deficiency in Mice Reveals Multiple Determinants of Risk for Congenital Heart Defects.
Volume: 14
Issue: 9
Pages: e2000197
Publication  
First Author: Quilez S
Year: 2024
Journal: Front Cell Dev Biol
Title: Loss of Neogenin alters branchial arch development and leads to craniofacial skeletal defects.
Volume: 12
Pages: 1256465
Publication
First Author: Luo W
Year: 2015
Journal: Development
Title: Akt1 signaling coordinates BMP signaling and β-catenin activity to regulate second heart field progenitor development.
Volume: 142
Issue: 4
Pages: 732-42
Publication
First Author: Klaus A
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Wnt/β-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells.
Volume: 109
Issue: 27
Pages: 10921-6
Publication
First Author: Kong P
Year: 2014
Journal: Hum Mol Genet
Title: Tbx1 is required autonomously for cell survival and fate in the pharyngeal core mesoderm to form the muscles of mastication.
Volume: 23
Issue: 16
Pages: 4215-31
Publication
First Author: Watanabe Y
Year: 2006
Journal: Development
Title: Activation of Notch1 signaling in cardiogenic mesoderm induces abnormal heart morphogenesis in mouse.
Volume: 133
Issue: 9
Pages: 1625-34
Publication
First Author: Lee D
Year: 2008
Journal: Cell Stem Cell
Title: ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification.
Volume: 2
Issue: 5
Pages: 497-507
Publication      
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
Publication
First Author: Zhu Z
Year: 2024
Journal: Adv Sci (Weinh)
Title: Isl Identifies the Extraembryonic Mesodermal/Allantois Progenitors and is Required for Placenta Morphogenesis and Vasculature Formation.
Volume: 11
Issue: 32
Pages: e2400238
Publication
First Author: Stevens JD
Year: 2008
Journal: Differentiation
Title: Phylogenetic and expression analysis of the basic helix-loop-helix transcription factor gene family: genomic approach to cellular differentiation.
Volume: 76
Issue: 9
Pages: 1006-22
Publication
First Author: Lumayag S
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.
Volume: 110
Issue: 6
Pages: E507-16
Publication
First Author: Willnow T
Year: 2005
Journal: Organogenesis
Title: The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.
Volume: 2
Issue: 2
Pages: 42-7
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Islas JF
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors.
Volume: 109
Issue: 32
Pages: 13016-21
GXD Expression    
Probe: MGI:6456741
Assay Type: RT-PCR
Annotation Date: 2020-09-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610514
Stage: TS14
Assay Id: MGI:6456771
Age: embryonic day 9.0
Image: S2
Specimen Label: Mesp1 Cre/+; fl/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6456741
Assay Type: RT-PCR
Annotation Date: 2020-09-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610514
Stage: TS14
Assay Id: MGI:6456771
Age: embryonic day 9.0
Image: S2
Specimen Label: Mesp1 Cre/+; fl/fl
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7569200
Assay Type: RT-PCR
Annotation Date: 2023-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7569211
Age: embryonic day 13.5
Specimen Label: Mesp1 CRE/+ Hic2 FL/FL
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7569202
Assay Type: RT-PCR
Annotation Date: 2023-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7569213
Age: embryonic day 13.5
Specimen Label: Mesp1 CRE/+ Hic2 FL/FL
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7569203
Assay Type: RT-PCR
Annotation Date: 2023-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7569215
Age: embryonic day 13.5
Specimen Label: Mesp1 CRE/+ Hic2 FL/FL
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7569205
Assay Type: RT-PCR
Annotation Date: 2023-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7569217
Age: embryonic day 13.5
Specimen Label: Mesp1 CRE/+ Hic2 FL/FL
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7569198
Assay Type: RT-PCR
Annotation Date: 2023-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7569209
Age: embryonic day 13.5
Specimen Label: Mesp1 CRE/+ Hic2 FL/FL
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7569199
Assay Type: RT-PCR
Annotation Date: 2023-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7569210
Age: embryonic day 13.5
Specimen Label: Mesp1 CRE/+ Hic2 FL/FL
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7569201
Assay Type: RT-PCR
Annotation Date: 2023-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7569212
Age: embryonic day 13.5
Specimen Label: Mesp1 CRE/+ Hic2 FL/FL
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7328518
Assay Type: RT-PCR
Annotation Date: 2023-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7569216
Age: embryonic day 13.5
Specimen Label: Mesp1 CRE/+ Hic2 FL/FL
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7569207
Assay Type: RT-PCR
Annotation Date: 2023-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7569218
Age: embryonic day 13.5
Specimen Label: Mesp1 CRE/+ Hic2 FL/FL
Detected: true
Specimen Num: 2
Publication
First Author: Saga Y
Year: 2000
Journal: Trends Cardiovasc Med
Title: Mesp1 expression is the earliest sign of cardiovascular development.
Volume: 10
Issue: 8
Pages: 345-52
Allele
Name: mesoderm posterior 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
GXD Expression
Probe: MGI:5436618
Assay Type: RNA in situ
Annotation Date: 2012-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1675215
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5437238
Age: embryonic day 9.5
Image: 4L top & bottom
Note: Mesp1 and Mesp2 are co-expressed in almost the same region in the presomitic mesoderm.
Specimen Label: 4L top & bottom
Detected: true
Specimen Num: 3
Allele
Name: mesoderm posterior 1; endonuclease-mediated mutation 1, Makoto Sahara
Allele Type: Endonuclease-mediated
Attribute String: Recombinase
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 6.0-6.5
Stage: 9
Structure . Name: embryo
Notes: control embryo; is either Mesp1 +/+ or Mesp1 -/+ (as well as carrying Rosa and cardiac reporter alleles)
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 6.0-6.5
Stage: 9
Structure . Name: embryo
Notes: control embryo; is either Mesp1 +/+ or Mesp1 -/+ (as well as carrying Rosa and cardiac reporter alleles)
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 6.0-6.5
Stage: 9
Structure . Name: embryo
Notes: control embryo; is either Mesp1 +/+ or Mesp1 -/+ (as well as carrying Rosa and cardiac reporter alleles)
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 6.0-6.5
Stage: 9
Structure . Name: embryo
Notes: control embryo; is either Mesp1 +/+ or Mesp1 -/+ (as well as carrying Rosa and cardiac reporter alleles)
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 6.0-6.5
Stage: 9
Structure . Name: embryo
Notes: control embryo; is either Mesp1 +/+ or Mesp1 -/+ (as well as carrying Rosa and cardiac reporter alleles)
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 6.5-7.5
Stage: 10
Structure . Name: embryo
Notes: control embryo; is either Mesp1 +/+ or Mesp1 -/+ (as well as carrying Rosa and cardiac reporter alleles)
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 6.5-7.5
Stage: 10
Structure . Name: embryo
Notes: control embryo; is either Mesp1 +/+ or Mesp1 -/+ (as well as carrying Rosa and cardiac reporter alleles)
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 6.5-7.5
Stage: 10
Structure . Name: embryo
Notes: control embryo; is either Mesp1 +/+ or Mesp1 -/+ (as well as carrying Rosa and cardiac reporter alleles)
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 7.5-7.75
Stage: 11
Structure . Name: embryo
Notes: control embryo; is either Mesp1 +/+ or Mesp1 -/+ (as well as carrying Rosa and cardiac reporter alleles)
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 7.5-7.75
Stage: 11
Structure . Name: embryo
Notes: control embryo; is either Mesp1 +/+ or Mesp1 -/+ (as well as carrying Rosa and cardiac reporter alleles)
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 7.5-7.75
Stage: 11
Structure . Name: embryo
Notes: control embryo; is either Mesp1 +/+ or Mesp1 -/+ (as well as carrying Rosa and cardiac reporter alleles)
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 7.5-7.75
Stage: 11
Structure . Name: embryo
Notes: control embryo; is either Mesp1 +/+ or Mesp1 -/+ (as well as carrying Rosa and cardiac reporter alleles)
Curation Status: Curated
Allele
Name: mesoderm posterior 1; targeted mutation 1, Yumiko Saga
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: mesoderm posterior 2; targeted mutation 1, Yumiko Saga
Allele Type: Targeted
Attribute String: Null/knockout
Strain
Attribute String: mutant strain, congenic, targeted mutation
Allele
Name: transgene insertion 2, Yumiko Saga
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 1, Yumiko Saga
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Genotype
Symbol: Mesp1/Mesp2/Mesp1/Mesp2
Background: involves: C57BL/6 * CBA * ICR
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Mesp1/Mesp2/Mesp1/Mesp2
Background: involves: C57BL/6 * CBA * ICR
Zygosity: hm
Has Mutant Allele: true
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Allele
Name: transgene insertion 1, Yumiko Saga
Allele Type: Transgenic
Attribute String: Reporter
Publication
First Author: Morimoto M
Year: 2005
Journal: Nature
Title: The Mesp2 transcription factor establishes segmental borders by suppressing Notch activity.
Volume: 435
Issue: 7040
Pages: 354-9
Publication
First Author: Morimoto M
Year: 2007
Journal: Development
Title: The negative regulation of Mesp2 by mouse Ripply2 is required to establish the rostro-caudal patterning within a somite.
Volume: 134
Issue: 8
Pages: 1561-9
Publication
First Author: Bondue A
Year: 2010
Journal: Circ Res
Title: Mesp1: a key regulator of cardiovascular lineage commitment.
Volume: 107
Issue: 12
Pages: 1414-27
Protein Domain
Type: Family
Description: This class C basic helix-loop-helix (bHLH) family of transcription factors consists of mesogenin and orthologues MesP1 (mesoderm posterior protein 1) and MesP2. Mesogenin is involved in specifying the paraxial mesoderm, which gives rise to all future trunk and limb skeletal muscles in vertebrates []. MesP1 is expressed in the posterior part of the embryonic mesoderm and is expressed in cardiac progenitors during embryogenesis and required for cardiovascular development [, ]. Mesp2 plays a critical role in establishing the rostro-caudal patterning of each somite, as well as somite boundary formation [, ].
Allele
Name: mesoderm posterior 2; targeted mutation 3, Yumiko Saga
Allele Type: Targeted
Attribute String: Recombinase
Strain
Attribute String: transgenic, mutant stock
Allele
Name: transgene insertion D1, Yumiko Saga
Allele Type: Transgenic
Attribute String: Reporter
Strain
Attribute String: transgenic, mutant stock
Strain
Attribute String: transgenic, mutant stock
Allele
Name: transgene insertion 1, Yumiko Saga
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
Allele
Name: mesoderm posterior 2; targeted mutation 2, Yumiko Saga
Allele Type: Targeted
Attribute String: Inserted expressed sequence, Null/knockout
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: transgenic, mutant stock
Strain
Attribute String: transgenic, mutant stock