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Search results 501 to 529 out of 529 for Mesp2

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Type

Details

Score

Allele

Mesp2<tm16.1(Rbpj*)Ysa> | MGI:4867475

Name:	mesoderm posterior 2; targeted mutation 16.1, Yumiko Saga
Allele Type:	Targeted
Attribute String:	Dominant negative, Inserted expressed sequence, Null/knockout

•

Strain

MGI:6144631 | ICR.Cg-Tg(CAG-cat,-Mesp2)1Ysa/YsaRbrc

Attribute String:

mutant strain, congenic, transgenic

•

Genotype

Symbol:	Mesp1/Mesp1 Mesp2/Mesp2
Background:	involves: C57BL/6 * CBA
Zygosity:	cx
Has Mutant Allele:	true

•

Genotype

Symbol:	Mesp1/Mesp2/Mesp1<+> Mesp1/Mesp2/Mesp2
Background:	involves: C57BL/6 * CBA * ICR
Zygosity:	cx
Has Mutant Allele:	true

•

Genotype

Symbol:	Mesp2/Mesp2
Background:	involves: C57BL/6 * CBA
Zygosity:	hm
Has Mutant Allele:	true

•

Genotype

Symbol:	Mesp2/Mesp2
Background:	involves: C57BL/6 * CBA
Zygosity:	hm
Has Mutant Allele:	true

•

Genotype

Symbol:	Mesp2/Mesp2<+>
Background:	involves: C57BL/6 * CBA
Zygosity:	ht
Has Mutant Allele:	true

•

Genotype

Symbol:	Mesp2/Mesp2 Tcf15/Tcf15
Background:	involves: 129S7/SvEvBrd * C57BL/6 * CBA * ICR
Zygosity:	cx
Has Mutant Allele:	true

•

Publication

11369261 | -

First Author:	Saga Y
Year:	2000
Journal:	Trends Cardiovasc Med
Title:	Mesp1 expression is the earliest sign of cardiovascular development.
Volume:	10
Issue:	8
Pages:	345-52

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Publication

21148448 | -

First Author:	Bondue A
Year:	2010
Journal:	Circ Res
Title:	Mesp1: a key regulator of cardiovascular lineage commitment.
Volume:	107
Issue:	12
Pages:	1414-27

•

Protein Domain

IPR040259 | Mesogenin/MesP

Type:

Family

Description:

This class C basic helix-loop-helix (bHLH) family of transcription factors consists of mesogenin and orthologues MesP1 (mesoderm posterior protein 1) and MesP2. Mesogenin is involved in specifying the paraxial mesoderm, which gives rise to all future trunk and limb skeletal muscles in vertebrates []. MesP1 is expressed in the posterior part of the embryonic mesoderm and is expressed in cardiac progenitors during embryogenesis and required for cardiovascular development [, ]. Mesp2 plays a critical role in establishing the rostro-caudal patterning of each somite, as well as somite boundary formation [, ].

•

Strain

MGI:6474528 | STOCK Mesp1/Mesp2<tm1Ysa> Tg(Mesp1*-ALPL)2Ysa/YsaRbrc

Attribute String:

transgenic, mutant stock

•

Genotype

Symbol:	Mesp2/Mesp2
Background:	involves: C57BL/6 * CBA
Zygosity:	hm
Has Mutant Allele:	true

•

Genotype

Symbol:	Mesp1/Mesp2/Mesp1<+> Mesp1/Mesp2/Mesp2
Background:	involves: C57BL/6 * CBA * ICR
Zygosity:	cx
Has Mutant Allele:	true

•

Genotype

Symbol:	Mesp2/Mesp2 Psen1/Psen1
Background:	involves: C57BL/6 * CBA
Zygosity:	cx
Has Mutant Allele:	true

•

Genotype

Symbol:	Mesp2/Mesp2 Psen1/Psen1
Background:	involves: C57BL/6 * CBA
Zygosity:	cx
Has Mutant Allele:	true

•

Genotype

Symbol:	Mesp1/Mesp2/Mesp1<+> Mesp1/Mesp2/Mesp2
Background:	involves: C57BL/6 * CBA * ICR
Zygosity:	cx
Has Mutant Allele:	true

•

Genotype

Symbol:	Mesp1/Mesp2/Mesp1<+> Mesp1/Mesp2/Mesp2
Background:	involves: C57BL/6 * CBA * ICR
Zygosity:	cx
Has Mutant Allele:	true

•

Genotype

Symbol:	Mesp2/Mesp2
Background:	involves: C57BL/6 * CBA
Zygosity:	ht
Has Mutant Allele:	true

•

Publication

9736723 | J:49906

First Author:	Kenny DA
Year:	1998
Journal:	Proc Natl Acad Sci U S A
Title:	Identification and characterization of LMO4, an LMO gene with a novel pattern of expression during embryogenesis.
Volume:	95
Issue:	19
Pages:	11257-62

•

Publication

27185833 | J:236817

First Author:	Chiapparo G
Year:	2016
Journal:	J Cell Biol
Title:	Mesp1 controls the speed, polarity, and directionality of cardiovascular progenitor migration.
Volume:	213
Issue:	4
Pages:	463-77

•

Publication

18775957 | J:169874

First Author:	Sparrow DB
Year:	2008
Journal:	Hum Mol Genet
Title:	Mutation of Hairy-and-Enhancer-of-Split-7 in humans causes spondylocostal dysostosis.
Volume:	17
Issue:	23
Pages:	3761-6

•

Publication

25343988 | J:219229

First Author:	McInerney-Leo AM
Year:	2015
Journal:	Hum Mol Genet
Title:	Compound heterozygous mutations in RIPPLY2 associated with vertebral segmentation defects.
Volume:	24
Issue:	5
Pages:	1234-42

•

Publication

16385447 | J:205678

First Author:	Sparrow DB
Year:	2006
Journal:	Am J Hum Genet
Title:	Mutation of the LUNATIC FRINGE gene in humans causes spondylocostal dysostosis with a severe vertebral phenotype.
Volume:	78
Issue:	1
Pages:	28-37

•

Publication

14960495 | J:88580

First Author:	Cordes R
Year:	2004
Journal:	Development
Title:	Specification of vertebral identity is coupled to Notch signalling and the segmentation clock.
Volume:	131
Issue:	6
Pages:	1221-33

•

Protein

O08574

Organism:	Mus musculus/domesticus
Length:	370
Fragment?:	false

•

Protein

Q9JK54

Organism:	Mus musculus/domesticus
Length:	188
Fragment?:	false

•

Protein

P97309

Organism:	Mus musculus/domesticus
Length:	243
Fragment?:	false

•

Protein

A6H5V4

Organism:	Mus musculus/domesticus
Length:	370
Fragment?:	false

•

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