Type |
Details |
Score |
Publication |
First Author: |
Elsen GE |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map. |
Volume: |
110 |
Issue: |
10 |
Pages: |
4081-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Toronto Centre for Phenogenomics |
Year: |
2013 |
Journal: |
MGI Direct Data Submission |
Title: |
Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki N |
Year: |
2003 |
Journal: |
DNA Res |
Title: |
Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. |
Volume: |
10 |
Issue: |
4 |
Pages: |
167-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cobellis G |
Year: |
2005 |
Journal: |
Nucleic Acids Res |
Title: |
Tagging genes with cassette-exchange sites. |
Volume: |
33 |
Issue: |
4 |
Pages: |
e44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
MGC Data curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration |
Year: |
2001 |
|
Title: |
LocusLink Collaboration |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen J |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
Volume: |
100 |
Issue: |
17 |
Pages: |
9918-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Friedel RH |
Year: |
2007 |
Journal: |
Brief Funct Genomic Proteomic |
Title: |
EUCOMM--the European conditional mouse mutagenesis program. |
Volume: |
6 |
Issue: |
3 |
Pages: |
180-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bedogni F |
Year: |
2021 |
Journal: |
Front Mol Neurosci |
Title: |
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
Volume: |
14 |
|
Pages: |
686034 |
|
•
•
•
•
•
|
Publication |
First Author: |
GUDMAP Consortium |
Year: |
2004 |
Journal: |
www.gudmap.org |
Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Abe T |
Year: |
2014 |
Journal: |
Development |
Title: |
The NAV2 homolog Sickie regulates F-actin-mediated axonal growth in Drosophila mushroom body neurons via the non-canonical Rac-Cofilin pathway. |
Volume: |
141 |
Issue: |
24 |
Pages: |
4716-28 |
|
•
•
•
•
•
|
Allele |
Name: |
neuron navigator 2; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
14-3-3 and NAV2 interact to regulate neurite outgrowth and axon elongation. |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6405704 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-04-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1778728 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:6405702 |
Age: |
postnatal day 7 |
Image: |
5D |
Note: |
Expression was detected in oligodendrocytes. Staining overlapped with Nav2 stained cells in the Hyp mutant. |
Specimen Label: |
5D |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6405705 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-04-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1778728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6405703 |
Age: |
postnatal day 7 |
|
Note: |
Expression did not overlap with Nav2 stained cells fiber tract in the Hyp mutant. |
Specimen Label: |
not shown |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6405706 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-04-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1778728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6405707 |
Age: |
postnatal day 7 |
|
Note: |
Expression did not overlap with Nav2 stained cells fiber tract in the Hyp mutant. |
Specimen Label: |
not shown |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6405708 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-04-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1778728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6405709 |
Age: |
postnatal day 7 |
|
Note: |
Expression did not overlap with Nav2 stained cells fiber tract in the Hyp mutant. |
Specimen Label: |
not shown |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marzinke MA |
Year: |
2013 |
Journal: |
Arch Biochem Biophys |
Title: |
14-3-3ε and NAV2 interact to regulate neurite outgrowth and axon elongation. |
Volume: |
540 |
Issue: |
1-2 |
Pages: |
94-100 |
|
•
•
•
•
•
|
Allele |
Name: |
neuron navigator 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
223
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
296
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Schmidt KL |
Year: |
2009 |
Journal: |
Development |
Title: |
The cell migration molecule UNC-53/NAV2 is linked to the ARP2/3 complex by ABI-1. |
Volume: |
136 |
Issue: |
4 |
Pages: |
563-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Muley PD |
Year: |
2008 |
Journal: |
Dev Neurobiol |
Title: |
The atRA-responsive gene neuron navigator 2 functions in neurite outgrowth and axonal elongation. |
Volume: |
68 |
Issue: |
13 |
Pages: |
1441-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stringham EG |
Year: |
2009 |
Journal: |
Cell Adh Migr |
Title: |
Navigating the cell: UNC-53 and the navigators, a family of cytoskeletal regulators with multiple roles in cell migration, outgrowth and trafficking. |
Volume: |
3 |
Issue: |
4 |
Pages: |
342-6 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry include Nav1/2/3 from mammals, unc-53 from C. elegans. They contain a calponin homology (CH) domain in the N terminus, several coiled-coil regions, polyproline rich SH3 binding motifs, and an ATPases associated with diverse cellular activities domain (AAA domain) []. They are required for the migration of cells and neuronal processes. Nav2 has been shown to rescue the mechanosensory neuron outgrowth defects of unc-53 mutants []. Unc-53 has been found to bind to ABI-1, a regulator of Arp2/3 mediated actin filament nucleation []. The Drosophila Nav2 homologue Sickie, also included in this family, regulates F-actin-mediated axonal growth []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Maes T |
Year: |
2002 |
Journal: |
Genomics |
Title: |
Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans. |
Volume: |
80 |
Issue: |
1 |
Pages: |
21-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Felipe A |
Year: |
1994 |
Journal: |
J Biol Chem |
Title: |
Primary structure and differential expression during development and pregnancy of a novel voltage-gated sodium channel in the mouse. |
Volume: |
269 |
Issue: |
48 |
Pages: |
30125-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Taiwo O |
Year: |
2013 |
Journal: |
Epigenetics |
Title: |
DNA methylation analysis of murine hematopoietic side population cells during aging. |
Volume: |
8 |
Issue: |
10 |
Pages: |
1114-22 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1875
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
536
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2098
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1844
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
116
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
576
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
232
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
80
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
440
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
301
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
576
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
858
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2432
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2371
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2432
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2359
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2366
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2309
 |
Fragment?: |
false |
|
•
•
•
•
•
|