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Search results 501 to 600 out of 625 for Ncoa1

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Type Details Score
Publication
22859932 | J:189684
First Author: Wang Z
Year: 2012
Journal: PLoS One
Title: The transcriptional coactivators p/CIP and SRC-1 control insulin resistance through IRS1 in obesity models.
Volume: 7
Issue: 7
Pages: e36961
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Publication
17854779 | J:127266
 
First Author: Schmidt MV
Year: 2007
Journal: Brain Res
Title: Ontogeny of steroid receptor coactivators in the hippocampus and their role in regulating postnatal HPA axis function.
Volume: 1174
Pages: 1-6
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Publication
15983373 | J:99863
First Author: Ye X
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Roles of steroid receptor coactivator (SRC)-1 and transcriptional intermediary factor (TIF) 2 in androgen receptor activity in mice.
Volume: 102
Issue: 27
Pages: 9487-92
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Publication
19109434 | J:143510
First Author: Wang S
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Disruption of the SRC-1 gene in mice suppresses breast cancer metastasis without affecting primary tumor formation.
Volume: 106
Issue: 1
Pages: 151-6
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Publication
12138202 | J:78075
First Author: Gehin M
Year: 2002
Journal: Mol Cell Biol
Title: The function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIP.
Volume: 22
Issue: 16
Pages: 5923-37
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Publication
21035760 | J:167908
First Author: Duteil D
Year: 2010
Journal: Cell Metab
Title: The transcriptional coregulators TIF2 and SRC-1 regulate energy homeostasis by modulating mitochondrial respiration in skeletal muscles.
Volume: 12
Issue: 5
Pages: 496-508
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Publication
19383905 | J:148269
First Author: Qin L
Year: 2009
Journal: Cancer Res
Title: The steroid receptor coactivator-1 regulates twist expression and promotes breast cancer metastasis.
Volume: 69
Issue: 9
Pages: 3819-27
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Publication
9708794 | J:49107
First Author: Jain S
Year: 1998
Journal: Am J Pathol
Title: Differential expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) and its coactivators steroid receptor coactivator-1 and PPAR-binding protein PBP in the brown fat, urinary bladder, colon, and breast of the mouse.
Volume: 153
Issue: 2
Pages: 349-54
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Publication
16723356 | J:178277
First Author: Flajollet S
Year: 2006
Journal: J Biol Chem
Title: Distinct roles of the steroid receptor coactivator 1 and of MED1 in retinoid-induced transcription and cellular differentiation.
Volume: 281
Issue: 29
Pages: 20338-48
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Publication
9556555 | J:127192
First Author: Na SY
Year: 1998
Journal: J Biol Chem
Title: Steroid receptor coactivator-1 interacts with the p50 subunit and coactivates nuclear factor kappaB-mediated transactivations.
Volume: 273
Issue: 18
Pages: 10831-4
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Publication
16373399 | J:319988
First Author: Burgermeister E
Year: 2006
Journal: Mol Endocrinol
Title: A novel partial agonist of peroxisome proliferator-activated receptor-gamma (PPARgamma) recruits PPARgamma-coactivator-1alpha, prevents triglyceride accumulation, and potentiates insulin signaling in vitro.
Volume: 20
Issue: 4
Pages: 809-30
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Publication
10501088 | J:57723
First Author: Ning G
Year: 1999
Journal: In Vitro Cell Dev Biol Anim
Title: Structure and chromosomal locations of mouse steroid receptor coactivator gene family.
Volume: 35
Issue: 8
Pages: 481-6
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Publication
10381882 | J:64957
First Author: Chen D
Year: 1999
Journal: Science
Title: Regulation of transcription by a protein methyltransferase.
Volume: 284
Issue: 5423
Pages: 2174-7
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Publication
12754525 | J:160665
First Author: Puigserver P
Year: 2003
Journal: Nature
Title: Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction.
Volume: 423
Issue: 6939
Pages: 550-5
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Publication
29077881 | J:295872
First Author: Costantino S
Year: 2019
Journal: Eur Heart J
Title: Interplay among H3K9-editing enzymes SUV39H1, JMJD2C and SRC-1 drives p66Shc transcription and vascular oxidative stress in obesity.
Volume: 40
Issue: 4
Pages: 383-391
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Publication
18483622 | J:137697
First Author: Scheppke L
Year: 2008
Journal: J Clin Invest
Title: Retinal vascular permeability suppression by topical application of a novel VEGFR2/Src kinase inhibitor in mice and rabbits.
Volume: 118
Issue: 6
Pages: 2337-46
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Publication
30451821 | J:268322
First Author: He Z
Year: 2018
Journal: Nat Commun
Title: Sumoylation of RORγt regulates TH17 differentiation and thymocyte development.
Volume: 9
Issue: 1
Pages: 4870
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Publication
17962186 | J:128919
First Author: Guo D
Year: 2007
Journal: J Biol Chem
Title: Induction of nuclear translocation of constitutive androstane receptor by peroxisome proliferator-activated receptor alpha synthetic ligands in mouse liver.
Volume: 282
Issue: 50
Pages: 36766-76
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Publication
9434940 | J:42692
First Author: Sato H
Year: 1998
Journal: Mamm Genome
Title: A new mutation Rim3 resembling Re(den) is mapped close to retinoic acid receptor alpha (Rara) gene on mouse chromosome 11.
Volume: 9
Issue: 1
Pages: 20-5
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Publication
14993927 | J:101966
First Author: Mascrez B
Year: 2004
Journal: EMBO Rep
Title: Ligand-dependent contribution of RXRbeta to cholesterol homeostasis in Sertoli cells.
Volume: 5
Issue: 3
Pages: 285-90
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Publication
27728806 | J:236712
First Author: Duran A
Year: 2016
Journal: Cancer Cell
Title: p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer.
Volume: 30
Issue: 4
Pages: 595-609
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Publication
12514218 | J:81201
First Author: Nishihara E
Year: 2003
Journal: J Neurosci
Title: SRC-1 null mice exhibit moderate motor dysfunction and delayed development of cerebellar Purkinje cells.
Volume: 23
Issue: 1
Pages: 213-22
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Publication
24811170 | J:274009
First Author: Reineke EL
Year: 2014
Journal: J Biol Chem
Title: Steroid receptor coactivator-2 is a dual regulator of cardiac transcription factor function.
Volume: 289
Issue: 25
Pages: 17721-31
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15155786 | J:91558
First Author: Song KH
Year: 2004
Journal: Mol Endocrinol
Title: The atypical orphan nuclear receptor DAX-1 interacts with orphan nuclear receptor Nur77 and represses its transactivation.
Volume: 18
Issue: 8
Pages: 1929-40
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Publication
11076796 | J:66247
First Author: Naltner A
Year: 2000
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Temporal/spatial expression of nuclear receptor coactivators in the mouse lung.
Volume: 279
Issue: 6
Pages: L1066-74
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Publication
10803578 | J:61908
First Author: Martinez de Arrieta C
Year: 2000
Journal: Endocrinology
Title: Coactivator and corepressor gene expression in rat cerebellum during postnatal development and the effect of altered thyroid status.
Volume: 141
Issue: 5
Pages: 1693-8
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Publication
12709428 | J:222684
First Author: Wansa KD
Year: 2003
Journal: J Biol Chem
Title: The AF-1 domain of the orphan nuclear receptor NOR-1 mediates trans-activation, coactivator recruitment, and activation by the purine anti-metabolite 6-mercaptopurine.
Volume: 278
Issue: 27
Pages: 24776-90
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Publication
9192892 | J:42181
First Author: Torchia J
Year: 1997
Journal: Nature
Title: The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function.
Volume: 387
Issue: 6634
Pages: 677-84
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Publication
21195347 | J:169479
First Author: Chopra AR
Year: 2011
Journal: Cell Metab
Title: Cellular energy depletion resets whole-body energy by promoting coactivator-mediated dietary fuel absorption.
Volume: 13
Issue: 1
Pages: 35-43
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Publication
11891224 | J:76833
First Author: Gonzalez MM
Year: 2002
Journal: J Biol Chem
Title: Cross-repression, a functional consequence of the physical interaction of non-liganded nuclear receptors and POU domain transcription factors.
Volume: 277
Issue: 21
Pages: 18501-9
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Publication
10882104 | J:61840
First Author: Ito M
Year: 2000
Journal: Mol Cell
Title: Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action.
Volume: 5
Issue: 4
Pages: 683-93
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Publication
12446761 | J:80609
First Author: Kim SW
Year: 2002
Journal: Mol Cell Biol
Title: Multiple developmental defects derived from impaired recruitment of ASC-2 to nuclear receptors in mice: implication for posterior lenticonus with cataract.
Volume: 22
Issue: 24
Pages: 8409-14
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Publication
16109736 | J:104056
First Author: Winnay JN
Year: 2006
Journal: Mol Endocrinol
Title: Adrenocorticotropic hormone-mediated signaling cascades coordinate a cyclic pattern of steroidogenic factor 1-dependent transcriptional activation.
Volume: 20
Issue: 1
Pages: 147-66
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Publication
15681609 | J:96189
First Author: Guan HP
Year: 2005
Journal: Genes Dev
Title: Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes.
Volume: 19
Issue: 4
Pages: 453-61
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Publication
14519200 | J:85784
First Author: Yu J
Year: 2003
Journal: Genome Biol
Title: Annotation and analysis of 10,000 expressed sequence tags from developing mouse eye and adult retina.
Volume: 4
Issue: 10
Pages: R65
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Publication
26221073 | J:309486
First Author: Chen X
Year: 2015
Journal: Int J Biol Sci
Title: Knockout of SRC-1 and SRC-3 in Mice Decreases Cardiomyocyte Proliferation and Causes a Noncompaction Cardiomyopathy Phenotype.
Volume: 11
Issue: 9
Pages: 1056-72
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Publication
22982455 | J:189008
First Author: Jia Y
Year: 2012
Journal: Mech Dev
Title: Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene.
Volume: 129
Issue: 9-12
Pages: 193-207
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Publication
26098214 | J:224542
First Author: Gao L
Year: 2015
Journal: J Clin Invest
Title: Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition.
Volume: 125
Issue: 7
Pages: 2808-24
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Publication
28424251 | J:242229
First Author: Ran H
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Nuclear Shp2 directs normal embryo implantation via facilitating the ERα tyrosine phosphorylation by the Src kinase.
Volume: 114
Issue: 18
Pages: 4816-4821
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Publication
19737349 | J:159513
First Author: Huang J
Year: 2009
Journal: Liver Int
Title: Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells.
Volume: 29
Issue: 10
Pages: 1569-81
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Publication
24880616 | J:226885
First Author: Tannour-Louet M
Year: 2014
Journal: Nat Med
Title: Increased gene copy number of VAMP7 disrupts human male urogenital development through altered estrogen action.
Volume: 20
Issue: 7
Pages: 715-24
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Publication
18022353 | J:126799
First Author: Allis CD
Year: 2007
Journal: Cell
Title: New nomenclature for chromatin-modifying enzymes.
Volume: 131
Issue: 4
Pages: 633-6
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Publication
20436479 | J:157819
First Author: Shimogori T
Year: 2010
Journal: Nat Neurosci
Title: A genomic atlas of mouse hypothalamic development.
Volume: 13
Issue: 6
Pages: 767-75
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Publication
- | J:94077
     
First Author: Mutant Mouse Regional Resource Centers
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC)
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Publication
21731673 | J:174767
First Author: Tang F
Year: 2011
Journal: PLoS One
Title: Deterministic and stochastic allele specific gene expression in single mouse blastomeres.
Volume: 6
Issue: 6
Pages: e21208
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
22988430 | J:190636
 
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
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Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
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Publication
20412781 | J:140465
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Ncoa1<tm1.1So> | MGI:6442000
Name: nuclear receptor coactivator 1; targeted mutation 1.1, Steffi Oesterreich
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence
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Interaction Experiment
Li X (2023)
Description: Accumulation of NCOA1 dependent on HERC3 deficiency transactivates matrix metallopeptidases and promotes extracellular matrix degradation in intervertebral disc degeneration.
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Publication
36878279 | -
 
First Author: Li X
Year: 2023
Journal: Life Sci
Title: Accumulation of NCOA1 dependent on HERC3 deficiency transactivates matrix metallopeptidases and promotes extracellular matrix degradation in intervertebral disc degeneration.
Volume: 320
Pages: 121555
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Protein
P70383
Organism: Mus musculus/domesticus
Length: 61  
Fragment?: true
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Protein
Q3UX41
Organism: Mus musculus/domesticus
Length: 295  
Fragment?: false
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Protein Domain
IPR028187 | STAT6_C
Type: Domain
Description: This family represents the C terminus of mammalian STAT6 (signal transducer and activator of transcription 6). It contains an LXXLL motif which binds to NCOA1 (Nuclear receptor coactivator 1) [].
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Publication
22761580 | J:187174
First Author: Simeonova I
Year: 2012
Journal: PLoS Genet
Title: Fuzzy tandem repeats containing p53 response elements may define species-specific p53 target genes.
Volume: 8
Issue: 6
Pages: e1002731
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Protein Domain
IPR014920 | Nuc_rcpt_coact_Ncoa-typ
Type: Domain
Description: This entry represents the interlocking domain of the eukaryotic nuclear receptor coactivators Ncoa1, Ncoa2 and Ncoa3. The interlocking domain forms a 3-helical non-globular array that forms interlocked heterodimers with its target.Nuclear receptors are ligand-activated transcription factors involved in the regulation of many processes, including development, reproduction and homeostasis. Nuclear receptor coactivators act to modulate the function of nuclear receptors. Coactivators associate with promoters and enhancers primarily through protein-protein contacts to facilitate the interaction between DNA-bound transcription factors and the transcription machinery. In addition to their role as coactivators of various nuclear receptors, Ncoa1 and Ncoa3 both have histone acetyltransferase activity (), but Ncoa2 does not [, ].
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