|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 501 to 600 out of 1795 for Nkx2-5

0.013s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
First Author: Heallen T
Year: 2011
Journal: Science
Title: Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size.
Volume: 332
Issue: 6028
Pages: 458-61
Publication
First Author: Zhang H
Year: 2016
Journal: Nat Genet
Title: Genetic lineage tracing identifies endocardial origin of liver vasculature.
Volume: 48
Issue: 5
Pages: 537-43
Publication
First Author: Ye W
Year: 2016
Journal: Development
Title: A unique stylopod patterning mechanism by Shox2-controlled osteogenesis.
Volume: 143
Issue: 14
Pages: 2548-60
Publication
First Author: Bazzi H
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: STRIP1, a core component of STRIPAK complexes, is essential for normal mesoderm migration in the mouse embryo.
Volume: 114
Issue: 51
Pages: E10928-E10936
Publication
First Author: Risebro CA
Year: 2006
Journal: Development
Title: Hand1 regulates cardiomyocyte proliferation versus differentiation in the developing heart.
Volume: 133
Issue: 22
Pages: 4595-606
Publication
First Author: Klaus A
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Wnt/β-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells.
Volume: 109
Issue: 27
Pages: 10921-6
Publication
First Author: Dominguez MH
Year: 2023
Journal: Cell
Title: Graded mesoderm assembly governs cell fate and morphogenesis of the early mammalian heart.
Volume: 186
Issue: 3
Pages: 479-496.e23
Publication
First Author: Sereti KI
Year: 2018
Journal: Nat Commun
Title: Analysis of cardiomyocyte clonal expansion during mouse heart development and injury.
Volume: 9
Issue: 1
Pages: 754
Publication  
First Author: Dykes IM
Year: 2018
Journal: J Mol Cell Cardiol
Title: HIC2 regulates isoform switching during maturation of the cardiovascular system.
Volume: 114
Pages: 29-37
Publication
First Author: Dilg D
Year: 2016
Journal: PLoS One
Title: HIRA Is Required for Heart Development and Directly Regulates Tnni2 and Tnnt3.
Volume: 11
Issue: 8
Pages: e0161096
Publication  
First Author: Miyamoto M
Year: 2021
Journal: Biochem Biophys Res Commun
Title: Noncanonical Notch signals have opposing roles during cardiac development.
Volume: 577
Pages: 12-16
Publication
First Author: Zhang R
Year: 2015
Journal: PLoS One
Title: Heparan Sulfate Biosynthesis Enzyme, Ext1, Contributes to Outflow Tract Development of Mouse Heart via Modulation of FGF Signaling.
Volume: 10
Issue: 8
Pages: e0136518
Publication
First Author: Chen X
Year: 2019
Journal: Protein Cell
Title: Dgcr8 deletion in the primitive heart uncovered novel microRNA regulating the balance of cardiac-vascular gene program.
Volume: 10
Issue: 5
Pages: 327-346
Publication
First Author: Nomaru H
Year: 2021
Journal: Nat Commun
Title: Single cell multi-omic analysis identifies a Tbx1-dependent multilineage primed population in murine cardiopharyngeal mesoderm.
Volume: 12
Issue: 1
Pages: 6645
Publication
First Author: Torregrosa-Carrión R
Year: 2021
Journal: Sci Adv
Title: Adhesion G protein-coupled receptor Gpr126/Adgrg6 is essential for placental development.
Volume: 7
Issue: 46
Pages: eabj5445
Publication    
First Author: Ivanovitch K
Year: 2017
Journal: Elife
Title: Live imaging of heart tube development in mouse reveals alternating phases of cardiac differentiation and morphogenesis.
Volume: 6
Publication
First Author: Saba R
Year: 2019
Journal: Sci Rep
Title: Endocardium differentiation through Sox17 expression in endocardium precursor cells regulates heart development in mice.
Volume: 9
Issue: 1
Pages: 11953
Publication
First Author: Szumska D
Year: 2017
Journal: BMC Dev Biol
Title: Pcsk5 is required in the early cranio-cardiac mesoderm for heart development.
Volume: 17
Issue: 1
Pages: 6
Publication
First Author: Watanabe Y
Year: 2006
Journal: Development
Title: Activation of Notch1 signaling in cardiogenic mesoderm induces abnormal heart morphogenesis in mouse.
Volume: 133
Issue: 9
Pages: 1625-34
Publication  
First Author: Baik J
Year: 2016
Journal: Nat Commun
Title: Endoglin integrates BMP and Wnt signalling to induce haematopoiesis through JDP2.
Volume: 7
Pages: 13101
Publication
First Author: Chang Z
Year: 2010
Journal: Dev Biol
Title: Deletion of Akt1 causes heart defects and abnormal cardiomyocyte proliferation.
Volume: 347
Issue: 2
Pages: 384-91
Publication
First Author: Ma L
Year: 2005
Journal: Development
Title: Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning.
Volume: 132
Issue: 24
Pages: 5601-11
Publication
First Author: Lin Y
Year: 2007
Journal: Genesis
Title: Generation of an Frs2alpha conditional null allele.
Volume: 45
Issue: 9
Pages: 554-9
Publication
First Author: Leung C
Year: 2014
Journal: J Am Heart Assoc
Title: Rac1 signaling is critical to cardiomyocyte polarity and embryonic heart development.
Volume: 3
Issue: 5
Pages: e001271
Publication  
First Author: Gharibeh L
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: GATA6 is a regulator of sinus node development and heart rhythm.
Volume: 118
Issue: 1
Publication
First Author: Laforest B
Year: 2011
Journal: Dev Biol
Title: GATA5 interacts with GATA4 and GATA6 in outflow tract development.
Volume: 358
Issue: 2
Pages: 368-78
Publication
First Author: Boczonadi V
Year: 2014
Journal: Cardiovasc Res
Title: Scrib:Rac1 interactions are required for the morphogenesis of the ventricular myocardium.
Volume: 104
Issue: 1
Pages: 103-15
Publication
First Author: Voss AK
Year: 2012
Journal: Dev Cell
Title: MOZ regulates the Tbx1 locus, and Moz mutation partially phenocopies DiGeorge syndrome.
Volume: 23
Issue: 3
Pages: 652-63
Publication
First Author: Kalisch-Smith JI
Year: 2021
Journal: Nat Commun
Title: Maternal iron deficiency perturbs embryonic cardiovascular development in mice.
Volume: 12
Issue: 1
Pages: 3447
Publication  
First Author: Fulcoli FG
Year: 2016
Journal: Nat Commun
Title: Rebalancing gene haploinsufficiency in vivo by targeting chromatin.
Volume: 7
Pages: 11688
Publication
First Author: Molkentin JD
Year: 1997
Journal: Genes Dev
Title: Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis.
Volume: 11
Issue: 8
Pages: 1061-72
Publication
First Author: Maitra M
Year: 2009
Journal: Dev Biol
Title: Interaction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac development.
Volume: 326
Issue: 2
Pages: 368-77
Publication
First Author: Xin M
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: A threshold of GATA4 and GATA6 expression is required for cardiovascular development.
Volume: 103
Issue: 30
Pages: 11189-94
Publication
First Author: Nadeau M
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: An endocardial pathway involving Tbx5, Gata4, and Nos3 required for atrial septum formation.
Volume: 107
Issue: 45
Pages: 19356-61
Publication  
First Author: Kim BJ
Year: 2018
Journal: Dis Model Mech
Title: RERE deficiency leads to decreased expression of GATA4 and the development of ventricular septal defects.
Volume: 11
Issue: 9
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Nakazawa M
Year: 2011
Journal: J Mol Cell Cardiol
Title: Inositol 1,4,5-trisphosphate receptors are essential for the development of the second heart field.
Volume: 51
Issue: 1
Pages: 58-66
Publication  
First Author: Uchida K
Year: 2010
Journal: PLoS One
Title: Gene knock-outs of inositol 1,4,5-trisphosphate receptors types 1 and 2 result in perturbation of cardiogenesis.
Volume: 5
Issue: 9
Publication
First Author: MacDonald ST
Year: 2013
Journal: Eur Heart J
Title: A cell-autonomous role of Cited2 in controlling myocardial and coronary vascular development.
Volume: 34
Issue: 32
Pages: 2557-65
Publication
First Author: Lin JI
Year: 2020
Journal: Commun Biol
Title: Mutation of LRP1 in cardiac neural crest cells causes congenital heart defects by perturbing outflow lengthening.
Volume: 3
Issue: 1
Pages: 312
Publication
First Author: van Loo PF
Year: 2007
Journal: Mol Cell Biol
Title: Transcription factor Sp3 knockout mice display serious cardiac malformations.
Volume: 27
Issue: 24
Pages: 8571-82
Publication
First Author: Poleshko A
Year: 2017
Journal: Cell
Title: Genome-Nuclear Lamina Interactions Regulate Cardiac Stem Cell Lineage Restriction.
Volume: 171
Issue: 3
Pages: 573-587.e14
Publication
First Author: Wang L
Year: 2022
Journal: Circ Res
Title: Endothelial Loss of ETS1 Impairs Coronary Vascular Development and Leads to Ventricular Non-Compaction.
Volume: 131
Issue: 5
Pages: 371-387
Publication
First Author: Yin Z
Year: 2008
Journal: Circulation
Title: Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis.
Volume: 117
Issue: 11
Pages: 1414-22
Publication
First Author: Chen JX
Year: 2012
Journal: Circ Res
Title: Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5.
Volume: 111
Issue: 1
Pages: 50-5
Publication
First Author: Gómez-Del Arco P
Year: 2024
Journal: Nat Commun
Title: The G4 resolvase Dhx36 modulates cardiomyocyte differentiation and ventricular conduction system development.
Volume: 15
Issue: 1
Pages: 8602
Publication
First Author: Gómez-Del Arco P
Year: 2016
Journal: Cell Metab
Title: The Chromatin Remodeling Complex Chd4/NuRD Controls Striated Muscle Identity and Metabolic Homeostasis.
Volume: 23
Issue: 5
Pages: 881-92
Publication
First Author: Lee MJ
Year: 2012
Journal: J Biol Chem
Title: Characterization of arginylation branch of N-end rule pathway in G-protein-mediated proliferation and signaling of cardiomyocytes.
Volume: 287
Issue: 28
Pages: 24043-52
Publication
First Author: Kehat I
Year: 2011
Journal: Circ Res
Title: Extracellular signal-regulated kinases 1 and 2 regulate the balance between eccentric and concentric cardiac growth.
Volume: 108
Issue: 2
Pages: 176-83
Publication
First Author: Jongbloed MR
Year: 2011
Journal: Dev Dyn
Title: Expression of Id2 in the second heart field and cardiac defects in Id2 knock-out mice.
Volume: 240
Issue: 11
Pages: 2561-77
Publication
First Author: Li P
Year: 2011
Journal: Development
Title: IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development.
Volume: 138
Issue: 9
Pages: 1795-805
Publication
First Author: Wang K
Year: 2019
Journal: BMC Dev Biol
Title: Differential roles of insulin like growth factor 1 receptor and insulin receptor during embryonic heart development.
Volume: 19
Issue: 1
Pages: 5
Publication
First Author: Shang Y
Year: 2013
Journal: PLoS Biol
Title: Transcriptional corepressors HIPK1 and HIPK2 control angiogenesis via TGF-β-TAK1-dependent mechanism.
Volume: 11
Issue: 4
Pages: e1001527
Publication
First Author: Yin Z
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation.
Volume: 99
Issue: 16
Pages: 10488-93
Publication
First Author: Krishnan J
Year: 2008
Journal: Circ Res
Title: Essential role of developmentally activated hypoxia-inducible factor 1alpha for cardiac morphogenesis and function.
Volume: 103
Issue: 10
Pages: 1139-46
Publication
First Author: Niu Z
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Serum response factor orchestrates nascent sarcomerogenesis and silences the biomineralization gene program in the heart.
Volume: 105
Issue: 46
Pages: 17824-9
Publication
First Author: Chinchilla A
Year: 2011
Journal: Circ Cardiovasc Genet
Title: PITX2 insufficiency leads to atrial electrical and structural remodeling linked to arrhythmogenesis.
Volume: 4
Issue: 3
Pages: 269-79
Publication
First Author: Windmueller R
Year: 2020
Journal: Cell Rep
Title: Direct Comparison of Mononucleated and Binucleated Cardiomyocytes Reveals Molecular Mechanisms Underlying Distinct Proliferative Competencies.
Volume: 30
Issue: 9
Pages: 3105-3116.e4
Publication
First Author: Risebro CA
Year: 2009
Journal: Development
Title: Prox1 maintains muscle structure and growth in the developing heart.
Volume: 136
Issue: 3
Pages: 495-505
Publication
First Author: Smart N
Year: 2007
Journal: Nature
Title: Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization.
Volume: 445
Issue: 7124
Pages: 177-82
Publication
First Author: Song L
Year: 2007
Journal: Circ Res
Title: Myocardial smad4 is essential for cardiogenesis in mouse embryos.
Volume: 101
Issue: 3
Pages: 277-85
Publication
First Author: Kuo CT
Year: 1997
Journal: Genes Dev
Title: GATA4 transcription factor is required for ventral morphogenesis and heart tube formation.
Volume: 11
Issue: 8
Pages: 1048-60
Publication
First Author: Yang J
Year: 2012
Journal: Cardiovasc Res
Title: Inhibition of Notch2 by Numb/Numblike controls myocardial compaction in the heart.
Volume: 96
Issue: 2
Pages: 276-85
Publication
First Author: Fujita J
Year: 2017
Journal: Cell Rep
Title: Ronin Governs Early Heart Development by Controlling Core Gene Expression Programs.
Volume: 21
Issue: 6
Pages: 1562-1573
Publication
First Author: Yu H
Year: 2021
Journal: Circulation
Title: LARP7 Protects Against Heart Failure by Enhancing Mitochondrial Biogenesis.
Volume: 143
Issue: 20
Pages: 2007-2022
Publication
First Author: Singh R
Year: 2012
Journal: Cell Mol Life Sci
Title: Tbx2 and Tbx3 induce atrioventricular myocardial development and endocardial cushion formation.
Volume: 69
Issue: 8
Pages: 1377-89
Publication
First Author: Maillet M
Year: 2010
Journal: J Biol Chem
Title: Heart-specific deletion of CnB1 reveals multiple mechanisms whereby calcineurin regulates cardiac growth and function.
Volume: 285
Issue: 9
Pages: 6716-24
Publication
First Author: Beketaev I
Year: 2015
Journal: Dev Dyn
Title: Critical role of YY1 in cardiac morphogenesis.
Volume: 244
Issue: 5
Pages: 669-80
Publication
First Author: Cossette SM
Year: 2014
Journal: Biol Open
Title: Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolism.
Volume: 4
Issue: 1
Pages: 48-61
Publication
First Author: Gründl M
Year: 2020
Journal: PLoS Genet
Title: Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes.
Volume: 16
Issue: 5
Pages: e1008818
Publication
First Author: Xu J
Year: 2019
Journal: J Biol Chem
Title: Shox2 regulates osteogenic differentiation and pattern formation during hard palate development in mice.
Volume: 294
Issue: 48
Pages: 18294-18305
Publication
First Author: Zhang J
Year: 2008
Journal: Development
Title: Frs2alpha-deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis.
Volume: 135
Issue: 21
Pages: 3611-22
Publication
First Author: Paul MH
Year: 2014
Journal: Cell Mol Life Sci
Title: Cardiac outflow tract development relies on the complex function of Sox4 and Sox11 in multiple cell types.
Volume: 71
Issue: 15
Pages: 2931-45
Publication
First Author: Lanier J
Year: 2009
Journal: Dev Dyn
Title: Brn3a regulates the transition from neurogenesis to terminal differentiation and represses non-neural gene expression in the trigeminal ganglion.
Volume: 238
Issue: 12
Pages: 3065-79
Publication
First Author: Xie L
Year: 2012
Journal: Dev Cell
Title: Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation.
Volume: 23
Issue: 2
Pages: 280-91
Publication
First Author: Koshiba-Takeuchi K
Year: 2006
Journal: Nat Genet
Title: Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart.
Volume: 38
Issue: 2
Pages: 175-83
Publication
First Author: Miao L
Year: 2018
Journal: Sci Rep
Title: Notch signaling regulates Hey2 expression in a spatiotemporal dependent manner during cardiac morphogenesis and trabecular specification.
Volume: 8
Issue: 1
Pages: 2678
Publication
First Author: Mu Y
Year: 2020
Journal: PLoS Genet
Title: O-linked β-N-acetylglucosamine transferase plays an essential role in heart development through regulating angiopoietin-1.
Volume: 16
Issue: 4
Pages: e1008730
Publication
First Author: Miao L
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Cardiomyocyte orientation modulated by the Numb family proteins-N-cadherin axis is essential for ventricular wall morphogenesis.
Volume: 116
Issue: 31
Pages: 15560-15569
Publication  
First Author: Miao L
Year: 2021
Journal: Cells
Title: The Spatiotemporal Expression of Notch1 and Numb and Their Functional Interaction during Cardiac Morphogenesis.
Volume: 10
Issue: 9
Publication  
First Author: Muñoz-Martín N
Year: 2019
Journal: Development
Title: Myc is dispensable for cardiomyocyte development but rescues Mycn-deficient hearts through functional replacement and cell competition.
Volume: 146
Issue: 3
Publication
First Author: Kuwabara Y
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: A human FLII gene variant alters sarcomeric actin thin filament length and predisposes to cardiomyopathy.
Volume: 120
Issue: 19
Pages: e2213696120
Publication
First Author: Togi K
Year: 2004
Journal: Mol Cell Biol
Title: Role of Hand1/eHAND in the dorso-ventral patterning and interventricular septum formation in the embryonic heart.
Volume: 24
Issue: 11
Pages: 4627-35
Publication
First Author: Shpargel KB
Year: 2012
Journal: PLoS Genet
Title: UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development.
Volume: 8
Issue: 9
Pages: e1002964
Publication
First Author: Yoshimura K
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Distinct function of 2 chromatin remodeling complexes that share a common subunit, Williams syndrome transcription factor (WSTF).
Volume: 106
Issue: 23
Pages: 9280-5
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication
First Author: Tetzlaff MT
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein.
Volume: 101
Issue: 10
Pages: 3338-45
Publication
First Author: Kiefer SM
Year: 2008
Journal: Hum Mutat
Title: SALL1 truncated protein expression in Townes-Brocks syndrome leads to ectopic expression of downstream genes.
Volume: 29
Issue: 9
Pages: 1133-40
Publication
First Author: Caputo L
Year: 2015
Journal: Cell Stem Cell
Title: The Isl1/Ldb1 Complex Orchestrates Genome-wide Chromatin Organization to Instruct Differentiation of Multipotent Cardiac Progenitors.
Volume: 17
Issue: 3
Pages: 287-99
Publication
First Author: Grego-Bessa J
Year: 2023
Journal: Circ Res
Title: Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development.
Volume: 133
Issue: 11
Pages: 927-943
Publication
First Author: Bolte C
Year: 2011
Journal: PLoS One
Title: Expression of Foxm1 transcription factor in cardiomyocytes is required for myocardial development.
Volume: 6
Issue: 7
Pages: e22217
Publication
First Author: Yang Y
Year: 2024
Journal: iScience
Title: Maternal high-fat diet alters Tet-mediated epigenetic regulation during heart development.
Volume: 27
Issue: 9
Pages: 110631
Publication
First Author: Castagnaro L
Year: 2013
Journal: Immunity
Title: Nkx2-5(+)islet1(+) mesenchymal precursors generate distinct spleen stromal cell subsets and participate in restoring stromal network integrity.
Volume: 38
Issue: 4
Pages: 782-91
Publication
First Author: Fang S
Year: 2019
Journal: Nat Commun
Title: Tet inactivation disrupts YY1 binding and long-range chromatin interactions during embryonic heart development.
Volume: 10
Issue: 1
Pages: 4297
Publication
First Author: Gomez-Velazquez M
Year: 2017
Journal: PLoS Genet
Title: CTCF counter-regulates cardiomyocyte development and maturation programs in the embryonic heart.
Volume: 13
Issue: 8
Pages: e1006985
Publication
First Author: Hennig M
Year: 2019
Journal: Sci Rep
Title: Dietary protein restriction throughout intrauterine and postnatal life results in potentially beneficial myocardial tissue remodeling in the adult mouse heart.
Volume: 9
Issue: 1
Pages: 15126
Publication  
First Author: Magarin M
Year: 2016
Journal: J Mol Cell Cardiol
Title: Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress.
Volume: 97
Pages: 1-14
Publication
First Author: Cozzitorto C
Year: 2020
Journal: Dev Cell
Title: A Specialized Niche in the Pancreatic Microenvironment Promotes Endocrine Differentiation.
Volume: 55
Issue: 2
Pages: 150-162.e6
Publication
First Author: Villa Del Campo C
Year: 2014
Journal: Cell Rep
Title: Cell competition promotes phenotypically silent cardiomyocyte replacement in the mammalian heart.
Volume: 8
Issue: 6
Pages: 1741-1751
Publication
First Author: Prados B
Year: 2018
Journal: Cell Death Dis
Title: Myocardial Bmp2 gain causes ectopic EMT and promotes cardiomyocyte proliferation and immaturity.
Volume: 9
Issue: 3
Pages: 399