|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 501 to 568 out of 568 for Nkx3-2

<< First    < Previous  |  Next >    Last >>
0.021s
Type Details Score
GXD Expression    
Probe: MGI:4879388
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5541032
Age: embryonic day 15.5
Image: GUDMAP:5167
Specimen Label: GUDMAP:5167
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4879388
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5541032
Age: embryonic day 15.5
Image: GUDMAP:5168
Specimen Label: GUDMAP:5168
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:4428285
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5422600
Age: embryonic day 14.5
Specimen Label: MH3090; Specimen C4166
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:4428285
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1802422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422600
Age: embryonic day 14.5
Image: MH3090; Specimen C4166
Specimen Label: MH3090; Specimen C4166
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6179087
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6189845
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Bapx1
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:6179087
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6189845
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Bapx1
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:6179087
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6189845
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Bapx1
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:6179087
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6189845
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Bapx1
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:6179087
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6189845
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Bapx1
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:6179087
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6189845
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Bapx1
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:6179087
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6189845
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Bapx1
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:4879388
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5541032
Age: embryonic day 15.5
Image: GUDMAP:5167
Specimen Label: GUDMAP:5167
Detected: false
Specimen Num: 1
GXD Expression
Probe: MGI:4428285
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1768022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422600
Age: embryonic day 14.5
Image: MH3090; Specimen C4166
Note: Expression was detected in the skull (base and vault).
Specimen Label: MH3090; Specimen C4166
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4428285
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5422600
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: MH3090; Specimen C4166
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:1930115
Assay Type: RNA in situ
Annotation Date: 2012-10-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3264922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5438139
Age: embryonic day 14.5
Image: 7K
Specimen Label: 7K
Detected: true
Specimen Num: 16
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Carrillo MB
Year: 1997
Journal: Glycobiology
Title: Cloning and characterization of a sialidase from the murine histocompatibility-2 complex: low levels of mRNA and a single amino acid mutation are responsible for reduced sialidase activity in mice carrying the Neu1a allele.
Volume: 7
Issue: 7
Pages: 975-86
Publication
First Author: Rottier RJ
Year: 1998
Journal: Hum Mol Genet
Title: A point mutation in the neu-1 locus causes the neuraminidase defect in the SM/J mouse.
Volume: 7
Issue: 2
Pages: 313-21
Strain
Attribute String: inbred strain
Publication
First Author: White EJ
Year: 2018
Journal: J Biol Chem
Title: Sialidase down-regulation reduces non-HDL cholesterol, inhibits leukocyte transmigration, and attenuates atherosclerosis in ApoE knockout mice.
Volume: 293
Issue: 38
Pages: 14689-14706
Allele
Name: NK3 homeobox 2; targeted mutation 1, Robert E Hill
Allele Type: Targeted
Attribute String: Null/knockout
Allele    
Name: neuraminidase 1; a variant
Strain
Attribute String: congenic, spontaneous mutation
Publication
First Author: Potier M
Year: 1979
Journal: FEBS Lett
Title: Neuraminidase deficiency in the mouse.
Volume: 108
Issue: 2
Pages: 345-8
Publication
First Author: Womack JE
Year: 1982
Journal: Immunogenetics
Title: Mouse gene for neuraminidase activity (Neu-1) maps to the D end of H-2.
Volume: 16
Issue: 2
Pages: 177-80
Publication
First Author: Klein D
Year: 1982
Journal: Immunogenetics
Title: Polymorphism of the Apl (Neu-1) locus in the mouse.
Volume: 16
Issue: 2
Pages: 181-4
Publication
First Author: Yang A
Year: 2012
Journal: J Lipid Res
Title: Hypomorphic sialidase expression decreases serum cholesterol by downregulation of VLDL production in mice.
Volume: 53
Issue: 12
Pages: 2573-85
Publication
First Author: Kijimoto-Ochiai S
Year: 2018
Journal: Glycobiology
Title: Existence of NEU1 sialidase on mouse thymocytes whose natural substrate is CD5.
Volume: 28
Issue: 5
Pages: 306-317
Publication
First Author: Hildebrand CE
Year: 1985
Journal: Biochem Biophys Res Commun
Title: Regional linkage analysis of the dioxin-inducible P-450 gene family on mouse chromosome 9.
Volume: 130
Issue: 1
Pages: 396-406
Publication
First Author: Womack JE
Year: 1981
Journal: Science
Title: Gene for neuraminidase activity on mouse chromosome 17 near h-2: pleiotropic effects on multiple hydrolases.
Volume: 212
Issue: 4490
Pages: 63-5
Publication
First Author: Kijimoto-Ochiai S
Year: 2008
Journal: Glycoconj J
Title: Low expression of Neu2 sialidase in the thymus of SM/J mice-existence of neuraminidase positive cells "Neu-medullocyte" in the murine thymus.
Volume: 25
Issue: 8
Pages: 787-96
Publication
First Author: Guo J
Year: 2019
Journal: Circ Res
Title: Endothelial SIRT6 Is Vital to Prevent Hypertension and Associated Cardiorenal Injury Through Targeting Nkx3.2-GATA5 Signaling.
Volume: 124
Issue: 10
Pages: 1448-1461
Allele
Name: NK3 homeobox 2; targeted mutation 3.1, Thomas Lufkin
Allele Type: Targeted
Attribute String: Recombinase
Allele
Name: NK3 homeobox 2; targeted mutation 4.1, Thomas Lufkin
Allele Type: Targeted
Attribute String: Recombinase
Allele
Name: NK3 homeobox 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
Allele
Name: NK3 homeobox 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
Genotype
Symbol: Neu1/Neu1
Background: SM/J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Neu1/Neu1
Background: B6.SM-Neu1
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Nkx3-2/Nkx3-2
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Nkx3-2/Nkx3-2
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Zeng L
Year: 2002
Journal: Genes Dev
Title: Shh establishes an Nkx3.2/Sox9 autoregulatory loop that is maintained by BMP signals to induce somitic chondrogenesis.
Volume: 16
Issue: 15
Pages: 1990-2005
Publication
First Author: Darbellay F
Year: 2024
Journal: Nat Commun
Title: Pre-hypertrophic chondrogenic enhancer landscape of limb and axial skeleton development.
Volume: 15
Issue: 1
Pages: 4820
GXD Expression
Probe: MGI:7580419
Assay Type: RNA in situ
Annotation Date: 2024-02-06
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1612817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7580431
Age: embryonic day 10.5
Image: 7J
Note: Expression severely downregulated compared to control. Expression overlapping with Nkx3.2 is absent.
Specimen Label: 7J
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:7580421
Assay Type: RNA in situ
Annotation Date: 2024-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1612817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7580432
Age: embryonic day 10.5
Image: 8B
Note: Expression disrupted in band of mandibular arch mesenchyme corresponding to Nkx3.2 mesenchymal expression domain.
Specimen Label: 8B
Detected: true
Specimen Num: 12
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2012-08-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1686019
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:5430518
Age: embryonic day 11.5
Image: 1C
Note: Nkx3.1 expression domains are indistinguishable in heterozygous and homozygous Nkx3.2 mutants.
Specimen Label: 1C
Detected: true
Specimen Num: 3
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2012-08-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1686019
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:5430518
Age: embryonic day 11.5
Image: 1D
Note: Nkx3.1 expression domains are indistinguishable in heterozygous and homozygous Nkx3.2 mutants.
Specimen Label: 1D
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2012-08-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3116917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5430518
Age: embryonic day 10.5
Note: Nkx3.1 expression domains are indistinguishable in heterozygous and homozygous Nkx3.2 mutants.
Specimen Label: Not shown E10.5
Detected: true
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2012-08-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3116920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5430518
Age: embryonic day 12.5
Note: Nkx3.1 expression domains are indistinguishable in heterozygous and homozygous Nkx3.2 mutants.
Specimen Label: Not shown E12.5
Detected: true
Specimen Num: 6
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Nkx3-2/Nkx3-2<+>
Background: involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2012-08-07
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1618419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:5430518
Age: embryonic day 11.5
Image: 1C
Note: Nkx3.1 expression domains are indistinguishable in heterozygous and homozygous Nkx3.2 mutants.
Specimen Label: 1C
Detected: true
Specimen Num: 3
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2012-08-07
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1618419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:5430518
Age: embryonic day 11.5
Image: 1D
Note: Nkx3.1 expression domains are indistinguishable in heterozygous and homozygous Nkx3.2 mutants.
Specimen Label: 1D
Detected: true
Specimen Num: 4
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Nkx3-2/Nkx3-2<+>
Background: involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
Interaction Experiment
Description: Exogenous signal-independent nuclear IkappaB kinase activation triggered by Nkx3.2 enables constitutive nuclear degradation of IkappaB-alpha in chondrocytes.
Interaction Detail    
Role 2: bait
Type: physical
Role 1: prey
Name: Nkx3-1-Msx2
Relationship Type: colocalization
Interaction Detail    
Role 2: prey
Type: physical
Role 1: bait
Name: Nkx3-1-Msx2
Relationship Type: colocalization