Type |
Details |
Score |
Publication |
First Author: |
Shigehara T |
Year: |
2003 |
Journal: |
J Am Soc Nephrol |
Title: |
Inducible podocyte-specific gene expression in transgenic mice. |
Volume: |
14 |
Issue: |
8 |
Pages: |
1998-2003 |
|
•
•
•
•
•
|
Publication |
First Author: |
Haas ME |
Year: |
2016 |
Journal: |
Circulation |
Title: |
The Role of Proprotein Convertase Subtilisin/Kexin Type 9 in Nephrotic Syndrome-Associated Hypercholesterolemia. |
Volume: |
134 |
Issue: |
1 |
Pages: |
61-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yi M |
Year: |
2017 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Autophagy is activated to protect against podocyte injury in adriamycin-induced nephropathy. |
Volume: |
313 |
Issue: |
1 |
Pages: |
F74-F84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rutkowski JM |
Year: |
2013 |
Journal: |
J Am Soc Nephrol |
Title: |
Adiponectin promotes functional recovery after podocyte ablation. |
Volume: |
24 |
Issue: |
2 |
Pages: |
268-82 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Lama5/Lama5 Tg(NPHS2-rtTA2*M2)1Jbk/? Tg(tetO-LAMA5)1Jhm/? |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * FVB/N |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Wt1/Wt1 Tg(tetO-cre)LC1Bjd/? Tg(NPHS2-rtTA2*M2)1Jbk/? |
Background: |
involves: BALB/c * C57BL/6 * FVB/N |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Coq6/Coq6 Tg(NPHS2-cre)295Lbh/? |
Background: |
involves: C57BL/6 * C57BL/6N * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Coq8b/Coq8b Tg(NPHS2-cre)295Lbh/? |
Background: |
involves: C3H * C57BL/6 * C57BL/6N * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Srgap1/Srgap1 Tg(NPHS2-cre)295Lbh/? |
Background: |
involves: C57BL/6 * C57BL/6N * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Kctd15/Kctd15 Tg(NPHS2-cre)295Lbh/? |
Background: |
involves: C57BL/6J * C57BL/6N * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Kctd1/Kctd1 Tg(NPHS2-cre)295Lbh/? |
Background: |
involves: C57BL/6J * C57BL/6N * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Phb2/Phb2<+> Nphs2/Nphs2<+> |
Background: |
involves: C57BL/6NTac |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Phb2/Phb2 Nphs2/Nphs2<+> |
Background: |
involves: C57BL/6NTac |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(NPHS2-cre)295Lbh/? |
Background: |
involves: 129S4/SvJaeSor * C57BL/6 * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Tg(CAG-Bgeo/ALPP)1Lbe/? Tg(NPHS2-rtTA,tetO-cre)1Holt/? |
Background: |
involves: 129S1/Sv * 129X1/SvJ * FVB/N |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(NPHS2-icre/ERT2)1Dnsh/? |
Background: |
involves: 129S4/SvJaeSor * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(NPHS2-cre)295Lbh/? |
Background: |
B6.Cg-Gt(ROSA)26Sor Tg(NPHS2-cre)295Lbh |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(NPHS2-cre)295Lbh/? |
Background: |
involves: 129 * C57BL/6 * CD-1 * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(NPHS2-cre)295Lbh/? |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * ICR * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
68
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
94
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The band-7 protein family comprises a diverse set of membrane-bound proteins characterised by the presence of a conserved domain, the band-7 domain, also known as SPFH or PHB domain. The exact function of the band-7 domain is not known, but examples from animal and bacterial stomatin-type proteins demonstrate binding to lipids and the ability to assemble into membrane-bound oligomers that form putative scaffolds [].A variety of proteins belong to the band-7 family. These include the stomatins, prohibitins, flottins and the HflK/C bacterial proteins. Eukaryotic band 7 proteins tend to be oligomeric and are involved in membrane-associated processes. Stomatins are involved in ion channel function, prohibitins are involved in modulating the activity of a membrane-bound FtsH protease and the assembly of mitochondrial respiratory complexes, and flotillins are involved in signal transduction and vesicle trafficking [].Stomatin, also known as human erythrocyte membrane protein band 7.2b [], was first identified in the band 7 region of human erythrocyte membrane proteins. It is an oligomeric, monotopic membrane protein associated with cholesterol-rich membranes/lipid rafts. Human stomatin is ubiquitously expressed in all tissues; highly in hematopoietic cells, relatively low in brain. It is associated with the plasma membrane and cytoplasmic vesicles of fibroblasts, epithelial and endothelial cells [].Stomatin is believed to be involved in regulating monovalent cation transport through lipid membranes. Absence of the protein in hereditary stomatocytosis is believed to be the reason for the leakage of Na+and K+ions into and from erythrocytes []. Stomatin is also expressed in mechanosensory neurons, where it may interact directly with transduction components, including cation channels [].Stomatin proteins have been identified in various organisms, including Caenorhabditis elegans. There are nine stomatin-like proteins in C. elegans, MEC-2 being the one best characterised []. In mammals, other stomatin family members are stomatin-like proteins SLP1, SLP2 and SLP3, and NPHS2 (podocin), which display selective expression patterns []. Stomatin family members are oligomeric, they mostly localise to membrane domains, and in many cases have been shown to modulate ion channel activity.The stomatins and prohibitins, and to a lesser extent flotillins, are highly conserved protein families and are found in a variety of organisms ranging from prokaryotes to higher eukaryotes, whereas HflK and HflC homologues are only present in bacteria [].This entry represents the stomatins and stomatin-like proteins, including podicin, from a wide range of eukaryotes, bacteria, archaea and viruses. It excludes the HflK and HflC proteins, prohibitins and flotillins. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The band-7 protein family comprises a diverse set of membrane-bound proteins characterised by the presence of a conserved domain, the band-7 domain, also known as SPFH or PHB domain. The exact function of the band-7 domain is not known, but examples from animal and bacterial stomatin-type proteins demonstrate binding to lipids and the ability to assemble into membrane-bound oligomers that form putative scaffolds [].A variety of proteins belong to the band-7 family. These include the stomatins, prohibitins, flottins and the HflK/C bacterial proteins. Eukaryotic band 7 proteins tend to be oligomeric and are involved in membrane-associated processes. Stomatins are involved in ion channel function, prohibitins are involved in modulating the activity of a membrane-bound FtsH protease and the assembly of mitochondrial respiratory complexes, and flotillins are involved in signal transduction and vesicle trafficking [].Stomatin, also known as human erythrocyte membrane protein band 7.2b [], was first identified in the band 7 region of human erythrocyte membrane proteins. It is an oligomeric, monotopic membrane protein associated with cholesterol-rich membranes/lipid rafts. Human stomatin is ubiquitously expressed in all tissues; highly in hematopoietic cells, relatively low in brain. It is associated with the plasma membrane and cytoplasmic vesicles of fibroblasts, epithelial and endothelial cells [].Stomatin is believed to be involved in regulating monovalent cation transport through lipid membranes. Absence of the protein in hereditary stomatocytosis is believed to be the reason for the leakage of Na+and K+ions into and from erythrocytes []. Stomatin is also expressed in mechanosensory neurons, where it may interact directly with transduction components, including cation channels [].Stomatin proteins have been identified in various organisms, including Caenorhabditis elegans. There are nine stomatin-like proteins in C. elegans, MEC-2 being the one best characterised []. In mammals, other stomatin family members are stomatin-like proteins SLP1, SLP2 and SLP3, and NPHS2 (podocin), which display selective expression patterns []. Stomatin family members are oligomeric, they mostly localise to membrane domains, and in many cases have been shown to modulate ion channel activity.The stomatins and prohibitins, and to a lesser extent flotillins, are highly conserved protein families and are found in a variety of organisms ranging from prokaryotes to higher eukaryotes, whereas HflK and HflC homologues are only present in bacteria [].This entry matches Stomatin, HflK and HflC proteins. |
|
•
•
•
•
•
|
Publication |
First Author: |
Price MP |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
Stomatin modulates gating of acid-sensing ion channels. |
Volume: |
279 |
Issue: |
51 |
Pages: |
53886-91 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
385
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
395
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
385
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
395
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
265
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
395
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Gehl B |
Year: |
2014 |
Journal: |
Front Plant Sci |
Title: |
Mitochondrial Band-7 family proteins: scaffolds for respiratory chain assembly? |
Volume: |
5 |
|
Pages: |
141 |
|
•
•
•
•
•
|
Publication |
First Author: |
Goldstein BJ |
Year: |
2003 |
Journal: |
J Assoc Res Otolaryngol |
Title: |
Cloning and characterization of SLP3: a novel member of the stomatin family expressed by olfactory receptor neurons. |
Volume: |
4 |
Issue: |
1 |
Pages: |
74-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lapatsina L |
Year: |
2012 |
Journal: |
Eur J Cell Biol |
Title: |
Stomatin-domain proteins. |
Volume: |
91 |
Issue: |
4 |
Pages: |
240-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rungaldier S |
Year: |
2017 |
Journal: |
PLoS One |
Title: |
Structure-function analysis of human stomatin: A mutation study. |
Volume: |
12 |
Issue: |
6 |
Pages: |
e0178646 |
|
•
•
•
•
•
|
Publication |
First Author: |
Boehm M |
Year: |
2009 |
Journal: |
J Bacteriol |
Title: |
Structural and mutational analysis of band 7 proteins in the cyanobacterium Synechocystis sp. strain PCC 6803. |
Volume: |
191 |
Issue: |
20 |
Pages: |
6425-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Madhusudhan T |
Year: |
2015 |
Journal: |
Nat Commun |
Title: |
Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy. |
Volume: |
6 |
|
Pages: |
6496 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang W |
Year: |
2012 |
Journal: |
Cell Metab |
Title: |
Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells. |
Volume: |
15 |
Issue: |
2 |
Pages: |
186-200 |
|
•
•
•
•
•
|
Publication |
First Author: |
Badal SS |
Year: |
2016 |
Journal: |
Nat Commun |
Title: |
miR-93 regulates Msk2-mediated chromatin remodelling in diabetic nephropathy. |
Volume: |
7 |
|
Pages: |
12076 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhong Y |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
Arctigenin attenuates diabetic kidney disease through the activation of PP2A in podocytes. |
Volume: |
10 |
Issue: |
1 |
Pages: |
4523 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ducasa GM |
Year: |
2019 |
Journal: |
J Clin Invest |
Title: |
ATP-binding cassette A1 deficiency causes cardiolipin-driven mitochondrial dysfunction in podocytes. |
Volume: |
129 |
Issue: |
8 |
Pages: |
3387-3400 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fujita Y |
Year: |
2018 |
Journal: |
Sci Rep |
Title: |
An adjustment in BMP4 function represents a treatment for diabetic nephropathy and podocyte injury. |
Volume: |
8 |
Issue: |
1 |
Pages: |
13011 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu F |
Year: |
2010 |
Journal: |
J Am Soc Nephrol |
Title: |
Anion exchanger 1 interacts with nephrin in podocytes. |
Volume: |
21 |
Issue: |
9 |
Pages: |
1456-67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li J |
Year: |
2020 |
Journal: |
EMBO Rep |
Title: |
Smad4 promotes diabetic nephropathy by modulating glycolysis and OXPHOS. |
Volume: |
21 |
Issue: |
2 |
Pages: |
e48781 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brinkkoetter PT |
Year: |
2019 |
Journal: |
Cell Rep |
Title: |
Anaerobic Glycolysis Maintains the Glomerular Filtration Barrier Independent of Mitochondrial Metabolism and Dynamics. |
Volume: |
27 |
Issue: |
5 |
Pages: |
1551-1566.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hartleben B |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Role of the polarity protein Scribble for podocyte differentiation and maintenance. |
Volume: |
7 |
Issue: |
5 |
Pages: |
e36705 |
|
•
•
•
•
•
|
Publication |
First Author: |
Frahsek M |
Year: |
2019 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Cre recombinase toxicity in podocytes: a novel genetic model for FSGS in adolescent mice. |
Volume: |
317 |
Issue: |
5 |
Pages: |
F1375-F1382 |
|
•
•
•
•
•
|
Publication |
First Author: |
Steenhard BM |
Year: |
2010 |
Journal: |
Am J Pathol |
Title: |
Deletion of von Hippel-Lindau in glomerular podocytes results in glomerular basement membrane thickening, ectopic subepithelial deposition of collagen {alpha}1{alpha}2{alpha}1(IV), expression of neuroglobin, and proteinuria. |
Volume: |
177 |
Issue: |
1 |
Pages: |
84-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Harvey SJ |
Year: |
2007 |
Journal: |
Am J Pathol |
Title: |
Disruption of glomerular basement membrane charge through podocyte-specific mutation of agrin does not alter glomerular permselectivity. |
Volume: |
171 |
Issue: |
1 |
Pages: |
139-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brukamp K |
Year: |
2007 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Hypoxia and podocyte-specific Vhlh deletion confer risk of glomerular disease. |
Volume: |
293 |
Issue: |
4 |
Pages: |
F1397-407 |
|
•
•
•
•
•
|
Publication |
First Author: |
Canaud G |
Year: |
2013 |
Journal: |
Nat Med |
Title: |
AKT2 is essential to maintain podocyte viability and function during chronic kidney disease. |
Volume: |
19 |
Issue: |
10 |
Pages: |
1288-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Madhusudhan T |
Year: |
2017 |
Journal: |
Blood |
Title: |
Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function. |
Volume: |
130 |
Issue: |
12 |
Pages: |
1445-1455 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zimmerman SE |
Year: |
2018 |
Journal: |
J Am Soc Nephrol |
Title: |
Nephronectin Regulates Mesangial Cell Adhesion and Behavior in Glomeruli. |
Volume: |
29 |
Issue: |
4 |
Pages: |
1128-1140 |
|
•
•
•
•
•
|
Publication |
First Author: |
Soda K |
Year: |
2012 |
Journal: |
J Clin Invest |
Title: |
Role of dynamin, synaptojanin, and endophilin in podocyte foot processes. |
Volume: |
122 |
Issue: |
12 |
Pages: |
4401-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Song K |
Year: |
2017 |
Journal: |
J Biol Chem |
Title: |
Loss of mucin-type O-glycans impairs the integrity of the glomerular filtration barrier in the mouse kidney. |
Volume: |
292 |
Issue: |
40 |
Pages: |
16491-16497 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schiffer M |
Year: |
2015 |
Journal: |
Nat Med |
Title: |
Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models. |
Volume: |
21 |
Issue: |
6 |
Pages: |
601-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pace JA |
Year: |
2021 |
Journal: |
Sci Adv |
Title: |
Podocyte-specific KLF4 is required to maintain parietal epithelial cell quiescence in the kidney. |
Volume: |
7 |
Issue: |
36 |
Pages: |
eabg6600 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rogg M |
Year: |
2021 |
Journal: |
J Am Soc Nephrol |
Title: |
SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance. |
Volume: |
32 |
Issue: |
3 |
Pages: |
563-579 |
|
•
•
•
•
•
|
Publication |
First Author: |
Christov M |
Year: |
2018 |
Journal: |
JCI Insight |
Title: |
Inducible podocyte-specific deletion of CTCF drives progressive kidney disease and bone abnormalities. |
Volume: |
3 |
Issue: |
4 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Verissimo T |
Year: |
2023 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
PCK1 is a key regulator of metabolic and mitochondrial functions in renal tubular cells. |
Volume: |
324 |
Issue: |
6 |
Pages: |
F532-F543 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rayes J |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
The podoplanin-CLEC-2 axis inhibits inflammation in sepsis. |
Volume: |
8 |
Issue: |
1 |
Pages: |
2239 |
|
•
•
•
•
•
|
Publication |
First Author: |
Payne H |
Year: |
2017 |
Journal: |
Blood |
Title: |
Mice with a deficiency in CLEC-2 are protected against deep vein thrombosis. |
Volume: |
129 |
Issue: |
14 |
Pages: |
2013-2020 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sachs N |
Year: |
2012 |
Journal: |
J Clin Invest |
Title: |
Blood pressure influences end-stage renal disease of Cd151 knockout mice. |
Volume: |
122 |
Issue: |
1 |
Pages: |
348-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schell C |
Year: |
2013 |
Journal: |
J Am Soc Nephrol |
Title: |
N-wasp is required for stabilization of podocyte foot processes. |
Volume: |
24 |
Issue: |
5 |
Pages: |
713-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tagawa A |
Year: |
2016 |
Journal: |
Diabetes |
Title: |
Impaired Podocyte Autophagy Exacerbates Proteinuria in Diabetic Nephropathy. |
Volume: |
65 |
Issue: |
3 |
Pages: |
755-67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Höhne M |
Year: |
2013 |
Journal: |
Am J Pathol |
Title: |
Light microscopic visualization of podocyte ultrastructure demonstrates oscillating glomerular contractions. |
Volume: |
182 |
Issue: |
2 |
Pages: |
332-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bechtel W |
Year: |
2013 |
Journal: |
J Am Soc Nephrol |
Title: |
Vps34 deficiency reveals the importance of endocytosis for podocyte homeostasis. |
Volume: |
24 |
Issue: |
5 |
Pages: |
727-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pedigo CE |
Year: |
2016 |
Journal: |
J Clin Invest |
Title: |
Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury. |
Volume: |
126 |
Issue: |
9 |
Pages: |
3336-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee SR |
Year: |
2024 |
Journal: |
iScience |
Title: |
Nox4-SH3YL1 complex is involved in diabetic nephropathy. |
Volume: |
27 |
Issue: |
2 |
Pages: |
108868 |
|
•
•
•
•
•
|
Publication |
First Author: |
Henique C |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
Genetic and pharmacological inhibition of microRNA-92a maintains podocyte cell cycle quiescence and limits crescentic glomerulonephritis. |
Volume: |
8 |
Issue: |
1 |
Pages: |
1829 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rogg M |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
The WD40-domain containing protein CORO2B is specifically enriched in glomerular podocytes and regulates the ventral actin cytoskeleton. |
Volume: |
7 |
Issue: |
1 |
Pages: |
15910 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hartleben B |
Year: |
2010 |
Journal: |
J Clin Invest |
Title: |
Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice. |
Volume: |
120 |
Issue: |
4 |
Pages: |
1084-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Potla U |
Year: |
2014 |
Journal: |
J Clin Invest |
Title: |
Podocyte-specific RAP1GAP expression contributes to focal segmental glomerulosclerosis-associated glomerular injury. |
Volume: |
124 |
Issue: |
4 |
Pages: |
1757-69 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gödel M |
Year: |
2011 |
Journal: |
J Clin Invest |
Title: |
Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. |
Volume: |
121 |
Issue: |
6 |
Pages: |
2197-209 |
|
•
•
•
•
•
|
Publication |
First Author: |
Faria D |
Year: |
2014 |
Journal: |
Kidney Int |
Title: |
The calcium-activated chloride channel Anoctamin 1 contributes to the regulation of renal function. |
Volume: |
85 |
Issue: |
6 |
Pages: |
1369-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ren J |
Year: |
2022 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
IL-1 receptor signaling in podocytes limits susceptibility to glomerular damage. |
Volume: |
322 |
Issue: |
2 |
Pages: |
F164-F174 |
|
•
•
•
•
•
|
Publication |
First Author: |
Eremina V |
Year: |
2008 |
Journal: |
N Engl J Med |
Title: |
VEGF inhibition and renal thrombotic microangiopathy. |
Volume: |
358 |
Issue: |
11 |
Pages: |
1129-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
An YA |
Year: |
2023 |
Journal: |
Mol Metab |
Title: |
Endotrophin neutralization through targeted antibody treatment protects from renal fibrosis in a podocyte ablation model. |
Volume: |
69 |
|
Pages: |
101680 |
|
•
•
•
•
•
|
Publication |
First Author: |
May CJ |
Year: |
2023 |
Journal: |
Kidney Int |
Title: |
Podocyte protease activated receptor 1 stimulation in mice produces focal segmental glomerulosclerosis mirroring human disease signaling events. |
Volume: |
104 |
Issue: |
2 |
Pages: |
265-278 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu H |
Year: |
2013 |
Journal: |
Mol Cell Biol |
Title: |
Rac1 activation in podocytes induces rapid foot process effacement and proteinuria. |
Volume: |
33 |
Issue: |
23 |
Pages: |
4755-64 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor Tg(NPHS2-rtTA2*M2)1Jbk/Tg(NPHS2-rtTA2*M2)1Jbk Tg(tetO-cre)LC1Bjd/Tg(tetO-cre)LC1Bjd |
Background: |
involves: 129S4/SvJaeSor * BALB/c * C57BL/6 * FVB/N |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor Tg(NPHS2-rtTA2*M2)1Jbk/Tg(NPHS2-rtTA2*M2)1Jbk Tg(tetO-cre)LC1Bjd/? |
Background: |
involves: 129S4/SvJaeSor * BALB/c * C57BL/6 * FVB/N |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
353
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
212
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
286
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
287
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
287
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
399
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
197
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
399
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
399
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
287
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Stewart GW |
Year: |
1997 |
Journal: |
Int J Biochem Cell Biol |
Title: |
Stomatin. |
Volume: |
29 |
Issue: |
2 |
Pages: |
271-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Peng M |
Year: |
2008 |
Journal: |
PLoS Genet |
Title: |
Primary coenzyme Q deficiency in Pdss2 mutant mice causes isolated renal disease. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e1000061 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mitrofanova A |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
SMPDL3b modulates insulin receptor signaling in diabetic kidney disease. |
Volume: |
10 |
Issue: |
1 |
Pages: |
2692 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bollée G |
Year: |
2011 |
Journal: |
Nat Med |
Title: |
Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis. |
Volume: |
17 |
Issue: |
10 |
Pages: |
1242-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pitera JE |
Year: |
2012 |
Journal: |
Genesis |
Title: |
Generation of mice with a conditional null Fraser syndrome 1 (Fras1) allele. |
Volume: |
50 |
Issue: |
12 |
Pages: |
892-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fu J |
Year: |
2016 |
Journal: |
J Am Soc Nephrol |
Title: |
Comparison of Glomerular and Podocyte mRNA Profiles in Streptozotocin-Induced Diabetes. |
Volume: |
27 |
Issue: |
4 |
Pages: |
1006-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hathaway CK |
Year: |
2015 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Low TGFβ1 expression prevents and high expression exacerbates diabetic nephropathy in mice. |
Volume: |
112 |
Issue: |
18 |
Pages: |
5815-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang L |
Year: |
2017 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Podocyte-specific knockout of cyclooxygenase 2 exacerbates diabetic kidney disease. |
Volume: |
313 |
Issue: |
2 |
Pages: |
F430-F439 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jarad G |
Year: |
2011 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Dystroglycan does not contribute significantly to kidney development or function, in health or after injury. |
Volume: |
300 |
Issue: |
3 |
Pages: |
F811-20 |
|
•
•
•
•
•
|